The impact of population ageing on the labour force participation rate in Spain

Rationale Population ageing is one of the greatest structural challenges facing the Spanish economy. Foremost among its multiple effects is its contractionary impact on labour supply, which will foreseeably have major implications on both the functioning of the labour market and the potential growth or sustainability of public finances. Takeaways •Population ageing over the past decade has had an estimated negative impact of around 3.4 percentage points (pp) on Spain’s participation rate in 2022. This impact has been uneven by regions, with a sharper fall in the Cantabrian regions (Asturias, Cantabria and the Basque Country). •According to the latest National Statistics Institute’s population projections, the participation rate is set to drop a further 2.8 pp by 2030 owing to the continuing ageing process. Excluding the support of net immigration flows, the drop would be 1.6 pp greater. •In addition, the impact of ageing may deepen regional divergences, since the regions that have an older population and lower GDP per capita may be expected to experience the sharpest falls in the participation rate

Análisis del mercado objetivo del Centro de Estudio y Reparación de Maquinaria – CERMAQ FPM, Lima, 2021

El presente estudio es de tipo descriptivo donde se presenta como finalidad efectuar el respectivo análisis del mercado objetivo del Centro de Estudio y Reparación de Maquinaria – CERMAQ FPM, Lima, 2021. El cual se dedica a la formación técnica minera como en el sector automotor, en técnicas de operación, mantenimiento, reparación de equipos pesados. Una vez realizado el análisis del mercado se concluye que: El Centro de Estudio y Reparación de Maquinaria tiene como mercado objetivo mujeres y hombres con edad entre 20 a 50 años de los distritos segmentados de Lima. Egresados del colegio y que no pueden acceder estudios universitarios. De acuerdo con el análisis FODA finalmente se concluye que el Centro de Estudio y Reparación de Maquinaria – CERMAQ FPM puede obtener el posicionamiento dentro del mercado Limeño si es que considera las diferentes tácticas que le faciliten vencer debilidades y riesgos, y beneficiándose de las fortalezas y oportunidades. El análisis realizado será de gran beneficio para esta empresa ya que va facilitar para poner en práctica estrategias idóneas así lograr mejores resultados en cuanto a su crecimiento y rentabilidad

El impacto del envejecimiento poblacional sobre la evolución de la tasa de actividad en España

Motivación El proceso de envejecimiento poblacional supone uno de los mayores retos estructurales que afronta la economía española. Entre sus múltiples efectos, cabe destacar el impacto contractivo sobre la oferta de trabajo, que, previsiblemente, tendrá importantes repercusiones tanto sobre el funcionamiento del mercado de trabajo como sobre el crecimiento potencial o la sostenibilidad de las finanzas públicas. Ideas principales •El envejecimiento poblacional experimentado durante la última década habría tenido un impacto negativo de unos 3,4 puntos porcentuales (pp) sobre el nivel de la tasa de actividad en 2022 en España. Este impacto habría sido heterogéneo por regiones, con una caída más intensa en las regiones del Cantábrico. •De acuerdo con las últimas proyecciones poblacionales del Instituto Nacional de Estadística, la tasa de actividad caería, debido a la continuación del proceso de envejecimiento, 2,8 pp adicionales hasta 2030. Si no se tuviera en cuenta el soporte de los flujos netos de inmigración, la caída sería 1,6 pp superior. •Además, el impacto del envejecimiento puede ahondar las divergencias regionales, ya que las comunidades autónomas más envejecidas y con menor PIB per cápita experimentarían las mayores caídas de la tasa de actividad

Analysis of Arterial Blood Gas Values Based on Storage Time Since Sampling: An Observational Study

[Abstract] Aim: To evaluate the influence of time on arterial blood gas values after artery puncture is performed. Method: Prospective longitudinal observational study carried out with gasometric samples from 86 patients, taken at different time intervals (0 (T0), 15 (T15), 30 (T30) and 60 (T60) min), from 21 October 2019 to 21 October 2020. The study variables were: partial pressure of carbon dioxide, bicarbonate, hematocrit, hemoglobin, potassium, lactic acid, pH, partial pressure of oxygen, saturation of oxygen, sodium and glucose. Results: The initial sample consisted of a total of 90 patients. Out of all the participants, four were discarded as they did not understand the purpose of the study; therefore, the total number of participants was 86, 51% of whom were men aged 72.59 on average (SD: 16.23). In the intra-group analysis, differences in PCO2, HCO3, hematocrit, Hb, K+ and and lactic acid were observed between the initial time of the test and the 15, 30 and 60 min intervals. In addition, changes in pH, pO2, SO2, Na and glucose were noted 30 min after the initial sample had been taken. Conclusions: The variation in the values, despite being significant, has no clinical relevance. Consequently, the recommendation continues to be the analysis of the GSA at the earliest point to ensure the highest reliability of the data and to provide the patient with the most appropriate treatment based on those results

Cell viability assay in corneal endothelium

Resumen del póster publicado en el II Annual Meeting CINBIO abstracts book [Internet], p. 65[Abstract] Introduction: Endothelium is the inner layer of the cornea, which must be viable for transplanting. The limited availability of corneas makes necessary the developing of preservation techniques that allow a long storage without losing endothelial viability.Objectives: Optimization of a cell viability assay in preserved corneas.Methods: One half of an endothelium from a cornea that was storage in hypothermic conditions and an endothelium of a cryopreserved cornea were stained with LIVE/DEAD imaging kit and Hoechst. The other half of endothelium was the negative control. Corneal endothelia were imaged using a fluorescence microscope.Results: Four sort of cells were visualized on both endothelia: viable cells with high esterase activity, intermediate cells with low esterase activity, non-viable cells without esterase activity, and cells only stained by Hoechst. Conclusions: Triple stain is effectiveto detect different sort of cells in endothelium of preserved corneas, included viable cells, depending on their esterase enzymatic activity and on cell and nuclear membrane damage

The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients

Background: Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three days of mechanical ventilation in patients with COVID-19 intubated at ICU admission. Methods: Multicenter, observational, cohort study includes consecutive patients with COVID-19 admitted to 44 Spanish ICUs between February 25 and July 31, 2020, who required intubation at ICU admission and mechanical ventilation for more than three days. We collected demographic and clinical data prior to admission; information about clinical evolution at days 1 and 3 of mechanical ventilation; and outcomes. Results: Of the 2,095 patients with COVID-19 admitted to the ICU, 1,118 (53.3%) were intubated at day 1 and remained under mechanical ventilation at day three. From days 1 to 3, PaO2/FiO2 increased from 115.6 [80.0-171.2] to 180.0 [135.4-227.9] mmHg and the ventilatory ratio from 1.73 [1.33-2.25] to 1.96 [1.61-2.40]. In-hospital mortality was 38.7%. A higher increase between ICU admission and day 3 in the ventilatory ratio (OR 1.04 [CI 1.01-1.07], p = 0.030) and creatinine levels (OR 1.05 [CI 1.01-1.09], p = 0.005) and a lower increase in platelet counts (OR 0.96 [CI 0.93-1.00], p = 0.037) were independently associated with a higher risk of death. No association between mortality and the PaO2/FiO2 variation was observed (OR 0.99 [CI 0.95 to 1.02], p = 0.47). Conclusions: Higher ventilatory ratio and its increase at day 3 is associated with mortality in patients with COVID-19 receiving mechanical ventilation at ICU admission. No association was found in the PaO2/FiO2 variation

Guía Mexicana para el Diagnóstico y el Tratamiento de la Urticaria

La urticaria es una enfermedad que padece una quinta parte de la población en algún momento de su vida. Las guías inter- nacionales recientes han propuesto unos cambios de fondo en su diagnóstico y tratamiento, por lo que había la necesidad de crear una guía nacional y multidisciplinaria, con base amplia en los gremios de especialistas y médicos de primer contacto en México. ABSTRACT Urticaria is a disease that a fifth of the population shall suffer once in a lifetime. Recent clinical guidelines have proposed some fundamental changes in the diagnosis and treatment of urticaria, making the development of a national, multidisciplinary guideline, with wide acceptability among different professional groups –both specialists and primary health care workers–, necessary in Mexico

Resultados Semilleros de Investigación 2009-2010

La publicación recoge los doce informes finales de investigación presentados por los estudiantes de ocho Semilleros 1 y cuatro Semilleros 2, correspondientes a la convocatoria 2009–2010 y se constituye en el Número 25 de la Serie de Investigaciones en Construcción, si bien este es el primer Número publicado en formato digital que UNIJUS se permite poner a disposición no sólo de la comunidad universitaria, sino también de la sociedad colombiana e internacional, interesada en los temas estudiados por los jóvenes investigadores de la Facultad de Derecho, Ciencias Políticas y Sociales de la Universidad Nacional de Colombia