Riparian species and flow regime: ecological studies for application in environmental flow assessments and river restoration (Mijares river, Spain)

Riparian species and flow regime: ecological studies for application in environmental flow assessments and river restoration (Mijares river, Spain

Fauna de Ammonites del tránsito complejo Urgoniano-Flysch negro entre Germka y Deba (Albiense medio y superior, region Vascocantábrica Septentrional)

En este trabajo se describe la fauna de ammonites de los complejos Urgoniano y Supraurgoniano (Flysch Negro), entre Gernika y Deba (Bizkaia y Gipuzkoa). El Complejo Urgoniano está formado por altos carbonatados y surcos lutíticos separados por fallas activas. Las calizas son fundamentalmente micríticas con corales y rudistas, y las lutitas adyacentes presentan megabrechas calizas y conglomerados silíceos resedimentados. El Flysch Negro está constituido por capas métricas de areniscas turbidIticas que pasan lateralmente a lutitas y areniscas turbiditicas delgadas y a areniscas bioturbadas. Los ammonites encontrados en estas dos unidades se agrupan en dos asociaciones principales, que corresponden al Albiense medio (Complejo Urgoniano) y a la parte inferior del Albiense superior (Flysch Negro). Dentro de la primera asociación se incluyen especies de los siguientes géneros: Phylloceras, Anagaudryceras, Kossmatella, Tetragonites, Puzosia, Desmoceras, Lyelliceras, Tegoceras, Neophlycticeras, Metahamites y Hamites. La segunda asociación se caracteriza por la presencia de especies de: Kossmatella, Puzosia, Hysteroceras y Morton iceras. La fauna descrita es cosmopolita y presenta caracteres tanto atlánticos como del Tethys.The fauna of ammonites from the Urgonian and Supraurgonian (Black Flysch) complexes, between Gemika and Deba (Bizkaia and Gipuzkoa), is described. The Urgonian consist of limestone horsts and lutite troughs separated by active faults. Limestones are mainly rudist and coral micrites and the adjacent lutites enclose resedimented limestone megabreccias and quartz conglomerates. The Black Flysch is made up of thick sandy turbidites passing laterally to lutites and thin sandy turbidites and to thoroughly bioturbated sandstones. Two ammonite associations are distinguished from these units, corresponding to the Middle Albian (Urgoman complex) and to the early Upper Albian (Black Flysch complex). Species of the following genera are described within the first association (Middle Albian): Phylloceras, Anagaudryceras, Kossmatella, Tetragonites, Puzosia, Desmoceras, Lyeiiceras, Tegoceros, Neophlycticeras, Metahamites and Hamites. The second association (early Upper Albian) includes species of: Kossmatella, Puzosia, Hysteroceras and Mortoniceras. The fauna described is cosmopolitan and its constituent taxa show atlantic as well as tethyan characteristics

ESTUDIO PROSPECTIVO DE LA LECTURA DE LA TEMPERATURA TIMPÁNICA EN UNA UCI POLIVALENTE.

Es un estudio sobre la lectura de la temperatura timpánica comparándola con otros métodos de temperatura. El objetivo es conocer y determinar temperaturas medias que nos sirvan de referencia así como establecer diferencias con otras variables. Es un estudio prospectivo y observacional realizado en una UCI polivalente pequeña. Se midió la temperatura timpánica en ambos oídos, en axila, en arteria pulmonar y en el box a todos los pacientes posibles. Como resultados se obtuvieron 535 casos, edad media 68 años, 312 varones (58,3%), Temperatura en oído izquierdo (O.I.)37,087ºC, O.D.37, 001ºC, axilar 36,69ºC, arteria pulmonar 37,672ºC. Se obtuvo diferencia estadísticamente significativa entre las distintas lecturas con

Keypoint descriptor fusion with Dempster-Shafer Theory

Keypoint matching is the task of accurately nding the location of a scene point in two images. Many keypoint descriptors have been proposed in the literature aiming at providing robustness against scale, translation and rotation transformations, each having advantages and disadvantages. This paper proposes a novel approach to fuse the information from multiple keypoint descriptors using Dempster-Shafer Theory of evidence [1], which has proven particularly e cient in combining sources of information providing incomplete, imprecise, biased, and con ictive knowledge. The matching results of each descriptor are transformed into an evidence distribution on which a con dence factor is computed making use of its entropy. Then, the evidence distributions are fused using Dempster-Shafer Theory (DST), considering its con dence. As result of the fusion, a new evidence distribution that improves the result of the best descriptor is obtained. Our method has been tested with SIFT, SURF, ORB, BRISK and FREAK descriptors using all possible combinations of them. Results on the Oxford keypoint dataset [2] shows that the proposed approach obtains an improvement of up to 10% compared to the best one (FREAK)

Correction: Management of bleeding following major trauma: a European guideline

SCOPUS: er.jinfo:eu-repo/semantics/publishe

Consensus of experts from the Spanish Pharmacogenetics and Pharmacogenomics Society and the Spanish Society of Medical Oncology for the genotyping of DPYD in cancer patients who are candidates for treatment with fluoropyrimidines

5-Fluorouracil (5-FU) and oral fluoropyrimidines, such as capecitabine, are widely used in the treatment of cancer, especially gastrointestinal tumors and breast cancer, but their administration can produce serious and even lethal toxicity. This toxicity is often related to the partial or complete deficiency of the dihydropyrimidine dehydrogenase (DPD) enzyme, which causes a reduction in clearance and a longer half-life of 5-FU. It is advisable to determine if a DPD deficiency exists before administering these drugs by genotyping DPYD gene polymorphisms. The objective of this consensus of experts, in which representatives from the Spanish Pharmacogenetics and Pharmacogenomics Society and the Spanish Society of Medical Oncology participated, is to establish clear recommendations for the implementation of genotype and/or phenotype testing for DPD deficiency in patients who are candidates to receive fluoropyrimidines. The genotyping of DPYD previous to treatment classifies individuals as normal, intermediate, or poor metabolizers. Normal metabolizers do not require changes in the initial dose, intermediate metabolizers should start treatment with fluoropyrimidines at doses reduced to 50%, and poor metabolizers are contraindicated for fluoropyrimidines

Zinc and silica are active components to efficiently treat in vitro simulated eroded dentin.

Objectives: Biomaterials for treating dentin hypersensitivity and dentin wear were evaluated, to efficiently occlude the dentinal tubules and to increase dentin resistance to abrasion. Materials and Methods: 24 dentin surfaces were treated with EDTA to expose dentinal tubules, and were: 1) non-brushed, 2) brushed with distilled water, or with pastes containing 3) Monetite, 4) Brushite, 5) Zn-Monetite, 6) Zn-Brushite, 7) Silica-Brushite and 8) NovaMin®. Topography, nanomechanical and chemical analysis were assessed on dentin surfaces (n=3) after artificial saliva immersion for 24 h, and after citric acid challenge. 21 further dentin specimens were created to evaluate dentin permeability after brushing, saliva storage and acid application (n=3). ANOVA, Student-Newman-Keuls (p<0.05) and Student t-test (p<0.001) were used. Results: Particles containing major proportion of silica attained intratubular occlusion by carbonate crystals (Raman carbonate peak heights: 15.17 and 19.24 au; complex modulus: 110 and 140 GPa, at intratubular dentin). When brushing with pastes containing higher proportion of silica or zinc, phosphate calcium compounds were encountered into tubules and over dentin surfaces (Raman intratubular phosphate peak heights: 49 to 70 au, and at the intertubular dentin: 78 to 92). The formed carbonated apatite and calcium phosphate layer were resistant to citric acid application. Zinc compounds drastically increased tubule occlusion, decreased dentin permeability (up to 30%) and augmented mechanical properties at the intertubular dentin (90-130 GPa), it was maintained after acid challenging. Conclusions: Zinc-containing pastes occluded dentinal tubules and improved dentin mechanical properties. Clinical Relevance: Using zinc as an active component to treat eroded dentin is encouraged.Projects RTC-2014-1731-1 and MAT2014-52036-P supported by the Ministry of Economy and Competitiveness and European Regional Development Fund

2013. Documento Sevilla de Consenso sobre Alternativas a la Transfusión de Sangre Alogénica. Actualización del Documento Sevilla

La transfusión de sangre alogénica (TSA) no es inocua, y como consecuencia han surgido múltiples alternativas a la misma (ATSA). Existe variabilidad respecto a las indicaciones y buen uso de las ATSA. Dependiendo de la especialidad de los médicos que tratan a los pacientes, el grado de anemia, la política transfusional, la disponibilidad de las ATSA y el criterio personal, estas se usan de forma variable. Puesto que las ATSA tampoco son inocuas y pueden no cumplir criterios de coste-efectividad, la variabilidad en su uso es inaceptable. Las sociedades españolas de Anestesiología y Reanimación (SEDAR), Hematología y Hemoterapia (SEHH), Farmacia Hospitalaria (SEFH), Medicina Intensiva y Unidades Coronarias (SEMICYUC), Trombosis y Hemostasia (SETH) y Transfusiones Sanguíneas (SETS) han elaborado un documento de consenso para el buen uso de la ATSA. Un panel de expertos de las 6 sociedades ha llevado a cabo una revisión sistemática de la literatura médica y elaborado el 2013. Documento Sevilla de Consenso sobre Alternativas a la Transfusión de Sangre Alogénica. Solo se contempla las ATSA dirigidas a disminuir la transfusión de concentrado de hematíes. Se definen las ATSA como toda medida farmacológica y no farmacológica encaminada a disminuir la transfusión de concentrado de hematíes, preservando siempre la seguridad del paciente. La cuestión principal que se plantea en cada ítem se formula, en forma positiva o negativa, como: «La ATSA en cuestión reduce/no reduce la tasa transfusional». Para formular el grado de recomendación se ha usado la metodología Grades of Recommendation Assessment, Development and Evaluation (GRADE)

Incidence, clinical characteristics and management of inflammatory bowel disease in Spain: large-scale epidemiological study

(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD—Crohn’s disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)—during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100, 000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31–56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p < 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery. © 2021 by the authors. Licensee MDPI, Basel, Switzerland