154 research outputs found

    Multi-objective engineering shape optimization using differential evolution interfaced to the Nimrod/O tool

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    This paper presents an enhancement of the Nimrod/O optimization tool by interfacing DEMO, an external multiobjective optimization algorithm. DEMO is a variant of differential evolution – an algorithm that has attained much popularity in the research community, and this work represents the first time that true multiobjective optimizations have been performed with Nimrod/O. A modification to the DEMO code enables multiple objectives to be evaluated concurrently. With Nimrod/O’s support for parallelism, this can reduce the wall-clock time significantly for compute intensive objective function evaluations. We describe the usage and implementation of the interface and present two optimizations. The first is a two objective mathematical function in which the Pareto front is successfully found after only 30 generations. The second test case is the three-objective shape optimization of a rib-reinforced wall bracket using the Finite Element software, Code_Aster. The interfacing of the already successful packages of Nimrod/O and DEMO yields a solution that we believe can benefit a wide community, both industrial and academic

    Geographical disparities in core population coverage indicators for roll back malaria in Malawi

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    BACKGROUND: Implementation of known effective interventions would necessitate the reduction of malaria burden by half by the year 2010. Identifying geographical disparities of coverage of these interventions at small area level is useful to inform where greatest scaling-up efforts should be concentrated. They also provide baseline data against which future scaling-up of interventions can be compared. However, population data are not always available at local level. This study applied spatial smoothing methods to generate maps at subdistrict level in Malawi to serve such purposes. METHODS: Data for the following responses from the 2000 Malawi Demographic and Health Survey (DHS) were aggregated at subdistrict level: (1) households possessing at least one bednet; (2) children under 5 years who slept under a bednet the night before the survey; (3) bednets retreated with insecticide within past 6-12 months preceding the survey; (4) children under 5 who had fever two weeks before the survey and received treatment within 24 hours from the onset of fever; and (5) women who received intermittent preventive treatment of malaria during their last pregnancy. Each response was geographically smoothed at subdistrict level by applying conditional autoregressive models using Markov Chain Monte Carlo simulation techniques. RESULTS: The underlying geographical patterns of coverage of indicators were more clear in the smoothed maps than in the original unsmoothed maps, with relatively high coverage in urban areas than in rural areas for all indicators. The percentage of households possessing at least one bednet was 19% (95% credible interval (CI): 16-21%), with 9% (95% CI: 7-11%) of children sleeping under a net, while 18% (95% CI: 16-19%) of households had retreated their nets within past 12 months prior to the survey. The northern region and lakeshore areas had high bednet coverage, but low usage and re-treatment rates. Coverage rate of children who received antimalarial treatment within 24 hours after onset of fever was consistently low for most parts of the country, with mean coverage of 4.8% (95% CI: 4.5-5.0%). About 48% (95% CI: 47-50%) of women received antimalarial prophylaxis during their pregnancy, with highest rates in the southern and northern areas. CONCLUSION: The striking geographical patterns, for example between predominantly urban and rural areas, may reflect spatial differences in provider compliance or coverage, and can partly be explained by socio-economic and cultural differences. The wide gap between high bed net coverage and low retreatment rates may reflect variation in perceptions about malaria, which may be addressed by implementing information, education and communication campaigns or introducing long lasting insecticide nets. Our results demonstrate that DHS data, with appropriate methodology, can provide acceptable estimates at sub-national level for monitoring and evaluation of malaria control goals

    Developing critical and theoretical approaches to educational technology research and practice

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    Considerable prior literature reflecting on the evolution of the field of educational technology by numerous research experts has considered the extent of criticality within the field and found it somewhat wanting (Bulfin, Johnson & Bigum, 2015; Haßler, Major & Hennessy, 2016; Jameson, 2013; Latchem, 2014; Oliver, 2011, 2016; Selwyn, 2007, 2011, 2015). Challenges include considerations of whether research findings (OECD, 2015)indicating worrying findings about the negative influence of excessive computer usage are really being considered and taken up in research, policy and practice in the field. This 50th Anniversary Special Section called for submissions to consider the extent to which Selwyn and others are justified in asserting that much research in the field has engaged in 'previous decades of technological "boosterism," hyperbole, and outright evangelism' rather than genuine searching inquiry (Selwyn, 2015). The section considers the need for greater critical (Bulfin et al., 2015), challenging and questioning 'e-leadership' of the field by those who are practising within it (Jameson, 2015). Prior evaluation of theoretical perspectives such as Activity Theory and theories on e-learning, relate to this (Isssroff and Scanlon, 2002; Nichols, 2003). The paper considers the extent to which the evidence emerging from research findings in educational technology is really engaging in a critical way with important global issues (Selwyn, 2015) to effect a beneficial influence on education policy, theory and practice, including, particularly, outcomes for learners. To what extent are educational technology researchers really leading, critiquing and shaping the field

    Primary health care delivery models in rural and remote Australia – a systematic review

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    © 2008 Wakerman et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Background One third of all Australians live outside of its major cities. Access to health services and health outcomes are generally poorer in rural and remote areas relative to metropolitan areas. In order to improve access to services, many new programs and models of service delivery have been trialled since the first National Rural Health Strategy in 1994. Inadequate evaluation of these initiatives has resulted in failure to garner knowledge, which would facilitate the establishment of evidence-based service models, sustain and systematise them over time and facilitate transfer of successful programs. This is the first study to systematically review the available published literature describing innovative models of comprehensive primary health care (PHC) in rural and remote Australia since the development of the first National Rural Health Strategy (1993–2006). The study aimed to describe what health service models were reported to work, where they worked and why. Methods A reference group of experts in rural health assisted in the development and implementation of the study. Peer-reviewed publications were identified from the relevant electronic databases. 'Grey' literature was identified pragmatically from works known to the researchers, reference lists and from relevant websites. Data were extracted and synthesised from papers meeting inclusion criteria. Results A total of 5391 abstracts were reviewed. Data were extracted finally from 76 'rural' and 17 'remote' papers. Synthesis of extracted data resulted in a typology of models with five broad groupings: discrete services, integrated services, comprehensive PHC, outreach models and virtual outreach models. Different model types assume prominence with increasing remoteness and decreasing population density. Whilst different models suit different locations, a number of 'environmental enablers' and 'essential service requirements' are common across all model types. Conclusion Synthesised data suggest that, moving away from Australian coastal population centres, sustainable models are able to address diseconomies of scale which result from large distances and small dispersed populations. Based on the service requirements and enablers derived from analysis of reported successful PHC service models, we have developed a conceptual framework that is particularly useful in underpinning the development of sustainable PHC models in rural and remote communities

    A review of population-based prevalence studies of physical activity in adults in the Asia-Pacific region

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    Background: Physical activity (PA) surveillance is an important component of non-communicable disease risk factor monitoring, and occurs through national and international surveillance systems. This review identifies population PA estimates for adults in the Asia-Pacific region, and examines variation in trends and prevalence rates obtained using different PA measures.Methods: Data were obtained from a MEDLINE search; World Health Organization&rsquo;s Global Health Infobase; Government websites and reference lists of relevant papers. Inclusion criteria included: national studies or those reporting large scale population-level data; data published from 2000 to 2010 and trend data prior; sample sizes over n = 1000, or fewer subjects in small nations.Results: In total, 56 population surveys from 29 Asia-Pacific countries were identified. Data on &lsquo;sufficient physical activity&rsquo; amongst adults were available from 45 studies (80%), with estimates ranging from 7% to 93% (median 62%, inter-quartile range 40%-85%). For 14 countries, estimates of &lsquo;sufficient activity&rsquo; were documented in multiple surveys using different methods, with the largest variation from 18% to 92% in Nepal. Median or mean METminutes/ day, reported in 20 studies, ranged from 6 to 1356. Serial trend data were available for 11 countries (22%), for periods spanning 2-10 years. Of these, five countries demonstrated increases in physical activity over time, four demonstrated decreases and three showed no changes.Conclusions: Many countries in the Asia-Pacific region collect population-level PA data. This review highlights differences in estimates within and between countries. Some differences may be real, others due to variation in the PA questions asked and survey methods used. Use of standardized protocols and measures, and combined reporting of data are essential goals of improved international PA surveillance.<br /

    Study of the doubly charmed tetraquark T+cc

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    Quantum chromodynamics, the theory of the strong force, describes interactions of coloured quarks and gluons and the formation of hadronic matter. Conventional hadronic matter consists of baryons and mesons made of three quarks and quark-antiquark pairs, respectively. Particles with an alternative quark content are known as exotic states. Here a study is reported of an exotic narrow state in the D0D0π+ mass spectrum just below the D*+D0 mass threshold produced in proton-proton collisions collected with the LHCb detector at the Large Hadron Collider. The state is consistent with the ground isoscalar T+cc tetraquark with a quark content of ccu⎯⎯⎯d⎯⎯⎯ and spin-parity quantum numbers JP = 1+. Study of the DD mass spectra disfavours interpretation of the resonance as the isovector state. The decay structure via intermediate off-shell D*+ mesons is consistent with the observed D0π+ mass distribution. To analyse the mass of the resonance and its coupling to the D*D system, a dedicated model is developed under the assumption of an isoscalar axial-vector T+cc state decaying to the D*D channel. Using this model, resonance parameters including the pole position, scattering length, effective range and compositeness are determined to reveal important information about the nature of the T+cc state. In addition, an unexpected dependence of the production rate on track multiplicity is observed

    Solar photocatalytic activity of anatase TiO2 nanocrystals synthesized by non-hydrolitic sol–gel method

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    Nanocrystalline anatase TiO2 was prepared through modified non-hydrolitic sol–gel method by reacting TiCl4 with benzyl alcohol at room temperature. The as synthesized anatase TiO2 was calcined at 450 °C for 5 h. The size and morphology of the as synthesized and calcined TiO2 nanoparticles were characterized using X-ray diffraction (XRD), field emission scanning electron microscope (FESEM), transmission electron microscopy (TEM) and BET surface area analysis. The band gap energy was measured using Kulbeka-Munk function and the electronic state of the prepared TiO2 was determined by X-ray photoelectron spectroscopy (XPS). The photocatalytic activity of the prepared samples was investigated by degrading 50 mg/L of 2,4-dichlorophenol (2,4-DCP) under natural sunlight as a source of irradiation. The obtained XRD patterns of both as synthesized and calcined TiO2 matches completely with the tetragonal anatase phase of TiO2. The as synthesized sample showed higher surface area (147.34 m2/g) with particles size ranging between 3 and 6 nm than the calcined titania (64.92 m2/g) of prarticle size ranging between 11 and 15 nm. Both the TiO2 samples showed excellent photocatalytic activity for the degradation of 2,4-DCP under natural sunlight irradiation. The complete removal of 2,4-DCP is obtained after 2.5 h for calcined TiO2 and 3.5 h for as synthesized TiO2 suggests that the prepared photocatalysts have the potential to degrade the organic pollutants. The degradation of 2,4-DCP followed first order kinetics
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