The Presence of Precursors of Benign Pre-B Lymphoblasts (Hematogones) in the Bone Marrow of a Paediatric Patient with Cytomegalovirus Infection

Hematogones are normal B-lymphoid precursors that multiply in the bone marrow of small children and of adults with ferropenic anaemia, neuroblastoma or idiopathic thrombocytopenic purpura. They are not normally found in peripheral blood, and the immunophenotype is virtually indistinguishable from that of B lymphoblasts. We discuss the case of a 3-month infant with an active cytomegalovirus infection, with hepatitis and pancytopenia associated with 13% hematogones in the bone marrow

Duración de la gestación en el ganado vacuno de raza Retinta

Este trabajo ha sido extraído de la tesina de licenciatura "Duración de la gestación en el ganado vacuno Retinto: Aplicación práctica en el plan de mejora", realizada por J. M. Pastor y dirigida por A. Molina. Esta fue delendida en la Universidad de Córdoba en 1996, obteniendo la calificación de Sobresaliente

Reactive Flash Sintering of High Entropy (Mn0.2Co0.2Ni0.2Cu 0.2X 0.2)Fe2O4 (X=Fe, Mg) Spinel Oxides

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Glauconite and phosphate peloids in Mesozoic carbonate sediments (eastern Subbetic Zone, Betic Cordilleras, SE Spain)

13 páginas, 4 figuras, 3 tablas.Glauconite and Ca phosphate peloids occur in Jurassic and Cretaceous bioclastic carbonate rocks from pelagic swell sequences of the Algayat-Crevillente Unit (Subbetic Zone). The size and morphology of the peloids are controlled by the bioclasts. The glauconite in both stratigraphic positions is K rich (>0.69 atoms p.f.u.) and shows well-defined 10 Aa lattice fringes. Poorly crystalline areas with a composition of Fe-smectite are found within the peloids, indicating the nature of the glauconitic precursor. This precursor would be formed in the shielded microenvironments of the bioclast and later transformed to glauconite by equilibration of peloids with sea water that culminated with the crystallization of a phosphatic phase. The greater presence of smectite areas in the Jurassic peloids and the lower K contents (0.69-0.81) of these glauconites, compared with the Cretaceous glauconites (0.81-0.89) can be explained by the calcitic early diagenetic cementation which stopped the process of glauconitization.Financial support was provided by the Research Groups 4065 and 4135 of the Junta de Andalucía and the Projects PB92-0961 and PB93-1150-CO2 of DGICYT.Peer reviewe

Utilization of centrate for the production of the marine microalgae Nannochloropsis gaditana

In this paper, the production of the microalga Nannochloropsis gaditana using centrate from the anaerobic digestion of treated urban wastewater is studied. For this, semicontinuous cultures were performed indoors at laboratory scale, under controlled conditions, supplying seawater with different centrate percentages from a real wastewater treatment plant as the culture medium. It was demonstrated that N. gaditana can be produced using solely centrate as the nutrient source but only at percentages below 50%. Above this level, inhibition is caused by an excess of ammonia, thus reducing productivity. In the 30-50% centrate range, biomass productivity was 0.4 g·l-1·day-1, equal to that measured when using Algal culture medium. Moreover, the biochemical composition of the biomass was also equal to that measured when using Algal culture medium, with the protein content in the 30-40%d.wt. range; whereas the lipid content ranged from 20 to 25%d.wt. Under these conditions, phosphorus depuration from the culture medium was in the 80-90% range while nitrogen depuration was only between 20 and 40%, indicating an excess of nitrogen in the centrate with respect to phosphorus. In spite of this phosphorus limitation, in the optimal centrate range (30-50% in the culture medium), the cells performed under optimal conditions, removing up to 35 mgN·l-1·day-1 and 5.7 mgP·l-1·day-1, with quantum yield values measuring 1.0-1.3 g·E-1. By supplying additional phosphorus, it was possible to enhance productivity and increase nitrate and phosphorus depuration to over 80%. The use of centrate is confirmed as a useful method for reducing microalgae production costs while also increasing process sustainability, especially when using biomass for bioenergy applications

The diagnosis of hereditary angioedema: family caregivers’ experiences

The aim of this study was to understand the experiences of family caregivers in the process of diagnosing hereditary angioedema. An interpretive and qualitative research methodology based on Gadamer’s philosophical hermeneutics was carried out. Data collection took place between May 2015 and August 2016 and included a focus group and in-depth interviews with 16 family caregivers. Two themes define the experiences of family caregivers: “Family life focuses on identifying the problem” and “Discovering and coping with a complex diagnosis.” The process of diagnosis generates fear, anxiety, uncertainty, and incomprehension. Family caregivers are the main support for patients diagnosed with hereditary angioedema. As they share in the patients’ suffering, they need a diagnosis to be established to be able to cope with the disease and offer support. Family health nurses can contribute to improving the coping process in this phase of the disease

Factores que afectan al crecimiento individual de terneros retintos en cebo

En este trabajo se han estudiado los principales factores que influyen sobre el comportamiento en cebo de terneros puros de raza Retinta. A pesar de que las condiciones en las que acceden al cebo los terneros Retintos están en la actualidad muy estandarizadas, siguen existiendo factores de mucho peso que condicionan el resultado del cebo. En este sentido destacan factores como la campaña y época de inicio del cebo. Otros factores significativos han sido el peso al destete y al inicio del cebo y la duración del cebo. Este trabajo complementa el publicado en el número anterior de esta revista en el cual se estudiaban los estadísticos descriptivos de las variables que caracterizan la fase de cebo de terneros de esta raza (Azor el al., 2004)

Evaluación de la competencia clínica de tutores de residentes de medicina familiar y comunitaria

ObjetivoDescribir la primera experiencia de una evaluación clínica objetiva y estructurada (ECOE) a tutores de residentes realizada en la comunidad autónoma de AndalucíaDiseñoObservacional descriptivoEmplazamientoUnidad Docente de Medicina Familiar y Comunitaria de HuelvaParticipantesTutores de residentes de medicina familiar y comunitariaMediciones principalesLos componentes competenciales que se consensuaron y ponderaron fueron los siguientes: anamnesis, exploración física, comunicación,habilidades técnicas, manejo, atención a la familia y actividades preventivas. La selección de las 10 situaciones clínicas de las que constaba la prueba se realizó utilizando unos criterios de priorización según la prevalencia, gravedad clínica, importancia de la prevención y del diagnóstico precoz, complejidad del caso, evaluación de la capacidad resolutiva del médico y simplicidad evaluativaResultadosRealizaron la ECOE 13 tutores. La edad media ± desviación estándar de los participantes fue de 42,8 ± 3,64 años. La prueba tuvo un coeficiente de fiabilidad (alfa de Cronbach) de 0,73. Por lo que se refiere a los resultados por participantes, la media global fue de 73 ± 6,2. Al analizar los resultados para los diferentes componentes competenciales, los mejores resultados se obtuvieron en la atención a la familia, la comunicación y las habilidades técnicasConclusionesLas pruebas de evaluación clínica objetiva y estructurada pueden ser útiles para la valoración de los tutores, con el objetivo de orientar su formación en los puntos débiles e incluso para, en un futuro no muy lejano, servir como instrumento para acreditar y reacreditar a los tutores de residentes de medicina familiar y comunitariaObjectivesWe show the first experience of the application of an objetive and structured clinical evaluation (OSCE) procedure to family medicine trainers, that has been carried out in Andalucia. The objective is to use a competence evaluation instrument that, in the short term, will be used not only for trainer accreditation but also for other public sanitary professionalsParticipantsTutors of family and commnity medicine residentsDesignObservational descriptiveSettingEducational unity of family medicinePrincipal measurementsThe competencial components to be assessed are the following: anamnesis, physical exploration, communication, technical skill, management, family attention y preventive activities. The clinical situations were selected using the following priority criteria: prevalence, clinical gravity, prevention and early diagnosis importance, case complexity, doctor's capacity of evaluation and simplicityResultsThirteen family medicine trainers took part in the OSCE. Their average age was 42.8±3.6 years. The test had an overall reliability coefficient (Cronbach's alpha) of 0.73. The overall mean score of the participants was 73±6.2. The best results about the competencial components were family attention, communication and technical skillConclusionsThe OSCE can be a convenient tool for family medical trainer evaluation, helping to orientate their education in the weak points and, in the near future, it can also be used as an instrument do accredit family medicine trainer