Gangrena de Fournier en paciente masculino con diabetes mellitus insulinodependiente: reporte de caso clínico

Introduction: congenital dacryocele is a rare entity due to nasolacrimal duct obstruction.Case report: female neonate, 17 days old, born after euthyroid delivery, at term, with no significant prenatal history. She presented with swelling of the right eye since birth, abundant conjunctival secretions and conjunctival hyperemia. Physical examination revealed the presence of an 8 mm diameter tumor in the area of the right lacrimal sac, not painful to palpation, bluish color. Complementary images such as ultrasound were indicated. The diagnosis of congenital dacryocele was determined. Non surgical treatment was decided. Warm compresses were indicated in the area of the affected lacrimal sac for five minutes, three times a day. It was decided to apply antibiotic therapy with tobramycin + dexamethasone in eye drops, one drop every four hours for 10 days. At the end of the treatment, the patient showed improvement, without the need of further interventions. Follow-up by ophthalmology was indicated.Conclusions: congenital dacryocele is a congenital entity of the lacrimal ducts of low incidence. Its diagnosis is clinical; however, imaging tests are necessary to rule out other entities. Conservative medical treatment may lead to resolution of the entity, with massage and antimicrobial therapy being useful; however, surgical intervention may be required.Introducción: el dacriocele congénito es una entidad poco frecuente por obstrucción del conducto nasolagrimal.Presentación del caso: neonato, del sexo femenino, de 17 días de nacida, producto de un parto eutócico, atérmino, sin antecedentes prenatales de importancia. Acude a los servicios por presentar inflamación en ojo derecho desde el nacimiento, secreciones conjuntivales abundantes e hiperemia conjuntival. A examen físico se constata presencia de un tumor de 8 mm de diámetro en zona del saco lagrimal derecho, no doloroso a la palpación, de coloración azulada. Se indica como complementario imágenes como ecografía. Se determina el diagnóstico de dacriocele congénito. Se decidió tratamiento no quirúrgico. Se indicó compresas tibias en la zona del saco lagrimal afectado por cinco minutos, tres veces al día. Se decide colocar antibioticoterapia con tobramicina + dexametasona en colirio, indicada una gota cada cuatro horas por 10 días. Al cabo del tratamiento se mostró mejoría, sin necesidad de otras intervenciones. Se indicó seguimiento por consulta de oftalmología.Conclusiones: el dacriocele congénito constituye una entidad congénita de las vías lagrimales de baja incidencia. Su diagnóstico es clínico, sin embargo, para descartar otras entidades resultan necesarias pruebas de imagen. El tratamiento médico conservador puede llevar a la resolución de la entidad, resultando útil el masaje sumado a terapia antimicrobiana; sin embargo, puede requerirse una intervención quirúrgica

Minimum Relevant Features to Obtain Explainable Systems for Predicting Cardiovascular Disease Using the Statlog Data Set

Learning systems have been focused on creating models capable of obtaining the best results in error metrics. Recently, the focus has shifted to improvement in the interpretation and explanation of the results. The need for interpretation is greater when these models are used to support decision making. In some areas, this becomes an indispensable requirement, such as in medicine. The goal of this study was to define a simple process to construct a system that could be easily interpreted based on two principles: (1) reduction of attributes without degrading the performance of the prediction systems and (2) selecting a technique to interpret the final prediction system. To describe this process, we selected a problem, predicting cardiovascular disease, by analyzing the well-known Statlog (Heart) data set from the University of California’s Automated Learning Repository. We analyzed the cost of making predictions easier to interpret by reducing the number of features that explain the classification of health status versus the cost in accuracy. We performed an analysis on a large set of classification techniques and performance metrics, demonstrating that it is possible to construct explainable and reliable models that provide high quality predictive performance

Teaching field geology in Spain

The Department of Crystallography and Mineralogy (Complutense University, Madrid) carries out every year a field geology course in San José - Rodalquilar (Almería, SE Spain. The region of Almería offers a unique opportunity for the teaching of field geology because of the variety of contrasted geologic scenarios: 1) Alpine metamorphic complexes; 2) Miocene sedimentary basins; 3) Miocene volcanic rocks including world-class pyroclastic deposits of almost every possible type; 4) epithermal gold and industrial minerals deposits; and 5) a second to none large fault zone (Carboneras Fault Zone, Serrata de Níjar). However, what makes different our field geology course is the fact that the students, in teams of 3 to 4 members, simulate a professional survey. Given that most students will end up working for companies, it is important that they receive some practical training before they leave the university. [RESUMEN] El Departamento de Cristalografía y Mineralogía de la Universidad Complutense de Madrid realiza anualmente un curso de geología de campo en San José – Rodalquilar (Almería, Sureste de España). La región de Almería ofrece una oportunidad única para la enseñanza de la geología de campo ya que en ella encontramos una gran variedad de escenarios geológicos: 1) complejos alpinos; 2) cuencas sedimentarias del Mioceno; 3) rocas volcánicas del Mioceno con extraordinarios ejemplos de diferentes tipos de depósitos piroclásticos; 4) yacimientos epitermales de oro, yacimientos de bentonitas, alunita, y zeolitas; y 5) una gran zona de falla (Zona de Falla de Carboneras, Serrata de Níjar). Sin embargo, lo que hace diferente nuestro curso de campo es el hecho de que los alumnos, en equipos de 3 o 4 miembros, simulan estar realizando un trabajo profesional. Dado que la mayor parte de los alumnos acabará trabajando para alguna empresa, nos parece importante que reciban alguna formación práctica antes de que acaben la carrera

Auditory P3a and P3b neural generators in schizophrenia: An adaptive sLORETA P300 localization approach

The present study investigates the neural substrates underlying cognitive processing in schizophrenia (Sz) patients. To this end, an auditory 3-stimulus oddball paradigm was used to identify P3a and P3b components, elicited by rare-distractor and rare-target tones, respectively. Event-related potentials (ERP) were recorded from 31 Sz patients and 38 healthy controls. The P3a and P3b brain-source generators were identified by time-averaging of low-resolution brain electromagnetic tomography (LORETA) current density images. In contrast with the commonly used fixed window of interest (WOI), we proposed to apply an adaptive WOI, which takes into account subjects’ P300 latency variability. Our results showed different P3a and P3b source activation patterns in both groups. P3b sources included frontal, parietal and limbic lobes, whereas P3a response generators were localized over bilateral frontal and superior temporal regions. These areas have been related to the discrimination of auditory stimulus and to the inhibition (P3a) or the initiation (P3b) of motor response in a cognitive task. In addition, differences in source localization between Sz and control groups were observed. Sz patients showed lower P3b source activity in bilateral frontal structures and the cingulate. P3a generators were less widespread for Sz patients than for controls in right superior, medial and middle frontal gyrus. Our findings suggest that target and distractor processing involves distinct attentional subsystems, both being altered in Sz. Hence, the study of neuroelectric brain information can provide further insights to understand cognitive processes and underlying mechanisms in Sz.Postprint (author's final draft

Anatomo-functional organization in brain networks

There are several studies focused on comparing rsFC networks with their structural substrate \cite{hagmann2008, honey2010}. However an accurate description of how anatomo-­functional connections are organized, both at physical and topological levels, is still to be defined. Here we present an approach to quantify the anatomo-functional organization and discuss its consistency

Experimental observation of phase transitions of a deformed Dicke model using a reconfigurable, bi-parametric electronic platform

We experimentally study the infinite-size limit of the Dicke model of quantum optics with a parity-breaking deformation strength that couples the system to an external bosonic reservoir. We focus on the dynamical consequences of such symmetry-breaking, which makes the classical phase space asymmetric with non-equivalent energy wells. We present an experimental implementation of the classical version of the deformed Dicke model using a state-of-the-art bi-parametric electronic platform. Our platform constitutes a playground for studying representative phenomena of the deformed Dicke model in electrical circuits with the possibility of externally controlling parameters and initial conditions. In particular, we investigate the dynamics of the ground state, various phase transitions, and the asymmetry of the energy wells as a function of the coupling strength $\gamma$ and the deformation strength $\alpha$ in the resonant case. Additionally, to characterize the various behavior regimes, we present a two-dimensional phase diagram as a function of the two intrinsic system parameters. The onset of chaos is also analyzed experimentally. Our findings provide a clear connection between theoretical predictions and experimental observations, demonstrating the usefulness of our bi-parametric electronic setup

Use of the entomopathogenic fungi \u3ci\u3eMetarhizium anisopliae, Cordyceps bassiana\u3c/i\u3e and \u3ci\u3eIsaria fumosorosea\u3c/i\u3e to control \u3ci\u3eDiaphorina citri\u3c/i\u3e (Hemiptera: Psyllidae) in Persian lime under field conditions

The Asian citrus psyllid Diaphorina citri Kuwayama is a destructive insect pest in citriculture, because it is an efficient vector of the proteobacteria ‘Candidatus Liberibacter asiaticus’ (Las), ‘Ca. L. africanus’ (Laf) and ‘Ca. L. americanus’ (Lam). These bacteria cause the ‘huanglongbing’ disease or ‘greening’ or ‘yellow dragon’ disease. The disease kills the plant and reduces fruit production. This insect pest is susceptible to entomopathogenic fungi, and we report the use of different strains of Metarhizium anisopliae, Cordyceps bassiana and Isaria fumosorosea against the nymphs and adults of D. citri under field conditions. The fungi were applied four times using a concentration of 2 £ 1013 conidia/ha with a time interval of 15 days between applications. The percentage of control of Cb 108, Ma 65, Ma 14 and Ifr 4 was 60, 50, 40 and 35% in nymphs, and 50, 50, 42 and 22% in adults, respectively. Metarhizium anisopliae, C. bassiana and I. fumosorosea applied on Persian lime groves are more effective in reducing higher density of nymphs than adults of D. citri

Topography of activation deficits in schizophrenia during P300 task related to cognition and structural connectivity

Background The study of cerebral underpinnings of schizophrenia may benefit from the high temporal resolution of electromagnetic techniques, but its spatial resolution is low. However, source imaging approaches such as low-resolution brain electromagnetic tomography (LORETA) allow for an acceptable compromise between spatial and temporal resolutions. Methods We combined LORETA with 32 channels and 3-Tesla diffusion magnetic resonance (Dmr) to study cerebral dysfunction in 38 schizophrenia patients (17 first episodes, FE), compared to 53 healthy controls. The EEG was acquired with subjects performing an odd-ball task. Analyses included an adaptive window of interest to take into account the interindividual variability of P300 latency. We compared source activation patters to distractor (P3a) and target (P3b) tones within- and between-groups. Results Patients showed a reduced activation in anterior cingulate and lateral and medial prefrontal cortices, as well as inferior/orbital frontal regions. This was also found in the FE patients alone. The activation was directly related to IQ in the patients and controls and to working memory performance in controls. Symptoms were unrelated to source activation. Fractional anisotropy in the tracts connecting lateral prefrontal and anterior cingulate regions predicted source activation in these regions in the patients. Conclusions These results replicate the source activation deficit found in a previous study with smaller sample size and a lower number of sensors and suggest an association between structural connectivity deficits and functional alterations.Postprint (author's final draft

Cooperative games and physical activities workshop

Talleres[ES] El objetivo de este taller es conocer y analizar las diferencias entre los conceptos de: “actividad física cooperativa” y “juego cooperativo”. Para ello se ha organizado el taller en dos partes: en la primera se realizará una sesión práctica, en la que vivenciar las características de ambos tipos de situación motriz; en la segunda parte se realizará una puesta en común entre todos los participantes, para analizar lo vivido y dejar claras las características propias de cada uno de los tipos de situación motriz practicado, reflexionando sobre sus posibilidades educativas y las alternativas para enriquecerlas desde una perspectiva pedagógica

Effect of pelagic Sargassum on in vitro dry matter and organic matter degradation, gas production, and protozoa population

This study determined the effect of pelagic Sargassum on in vitro dry matter and organic matter degradation, total gas production (TGP), and protozoa population. The treatments were different levels of Sargassum inclusion on a basal substrate (Stargrass hay; Cynodon nlemfuensis) as follows: T0 (control treatment based on Stargrass hay), T10 (90% Stargrass hay + 10% Sargassum), T20 (80% Stargrass hay + 20% Sargassum), and T30 (70% Stargrass hay + 30% Sargassum). Ruminal fermentation kinetics and protozoa population were determined during 72 h of in vitro incubations. Compared to control, dry matter degradability at 48 and 72 h and organic matter degradability at 24 and 48 h were higher in Sargassum treatments. TGP was lower with T20 at 48 h. The total population of protozoa and the concentration of Entodinium spp. were lower at T20 at 48 h and T30 at 72 h. Cl, S, Ca, K, and Zn (103, 5.97, 88.73, 285.70 g/kg, and 15,900 mg/kg) were high in Sargassum, reaching twice or even nine times higher than the contents in Stargrass (11.37, 1.60, 43.53, 87.73 g/kg, and 866.67 mg/kg). Overall, up to 30% pelagic Sargassum could be included in hay-based substrates from tropical grasses without negative effects on in vitro dry matter and organic matter degradability