1,865 research outputs found
Understanding and Modeling Currency Crises and Contagion
In the course of this thesis, I plan to explain and model currency crises and contagion. The rest of the thesis is organized as follows: Section II provides a literature review of currency crises and contagion. Section III describes the case of currency crisis in East Asia. Section IV tells the story of Thailand before and during the crisis from the perspective of a typical news reader. Section V brings the reader to the present situation of the topic and Section VI tries to replicate the role of investors in these events using a cellular automata model. Section VII concludes
Au@TiO2 Nanocomposites Synthesized by X-ray Radiolysis as Potential Radiosensitizers
Radiosensitization is a novel targeted therapy strategy where chemical compounds are being explored to enhance the sensitivity of the tissue to the effects of ionizing radiation. Among the different radiosensitizers alternatives, nanomaterials have shown promising results by enhancing tumor injury through the production of free radicals and reactive oxygen species (ROS). In this work, Gold-supported titania (Au@TiO2) nanocomposites were synthesized through an innovative strategy using X-ray irradiation, and their potential as radiosensitizers was investigated. Radiosensitization of Au@TiO2 nanocomposites was assessed by monitoring the decomposition of Methylene Blue (MB) under X-ray irradiation in the presence of the nanomaterial. Radiosensitization of Au@TiO2 was thoroughly investigated as a function of parameters such as Au loading, TiO2 particle size, nanomaterial concentration, different irradiation voltages, and dose rates. Results showed that the presence of Au@TiO2 increases significantly the absorbed dose, thus enhancing MB decomposition. The mechanism behind Au@TiO2 radiosensitization relies on their interaction with X-rays. TiO2 produces reactive ROS whereas Au leads to the generation of photoelectrons and Auger electrons upon exposure to X-rays. These species lead to an enhanced degradation rate of the dye, a feature that could translate to cancerous cells damage with minimal side effects. The radiosensitization effect of Au@TiO2 nanocomposites was also tested in biological settings using Microcystis Aeruginosa cells. The results showed an increase in cell damage when irradiated in the presence of Au@TiO2 nanocomposites. Au@TiO2 nanocomposites were fabricated using X-ray radiolytic synthesis, a method that diverges from conventional fabrication processes and leads to negligible by-product formation, an important feature for medical and catalytic applications. In this work, Au nanoparticles are supported on TiO2 with a mean particle size of either 6.5 nm or 21.6 nm, using different ligands such as NaOH or urea, and under different absorbed doses to determine the effects of these parameters on the nanomaterials’ characteristics. Overall, Au@TiO2 synthesized by X-rays showed remarkable promise as radiosensitizers, a concept relevant to a number of medical, biological and environmental applications
Microwave-assisted synthesis of 3-aminobenzo[b]thiophene scaffolds for the preparation of kinase inhibitors
Microwave irradiation of 2-halobenzonitriles and methyl thioglycolate in the presence of triethylamine in DMSO at 130 °C provides rapid access to 3-aminobenzo[b]thiophenes in 58–96% yield. This transformation has been applied in the synthesis of the thieno[2,3-b]pyridine core motif of LIMK1 inhibitors, the benzo[4,5]thieno[3,2-e][1,4]diazepin-5(2H)-one scaffold of MK2 inhibitors and a benzo[4,5]thieno[3,2-d]pyrimidin-4-one inhibitor of the PIM kinases
Design Aspects of a Broadband Beam-Reconfigurable Leaky-Wave Antenna
Design aspects of a novel beam-reconfigurable pla-nar series-fed array are addressed to achieve beam steering with frequency tunability over a relatively broad bandwidth. The design is possible thanks to the use of the complementary strip-slot, which is an innovative broadly matched microstrip radiator, and the careful selection of the phase shifter parameters.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
Primers resultats de l'eficàcia de depuració i de producció de biogàs d'un filtre anaerobi que tracta l'aigua residual de la fabricació de midó de patata
Different Responses in Mandarin Cultivars Uncover a Role of Cuticular Waxes in the Resistance to Citrus Canker
[EN] 'Okitsu' is a mandarin cultivar showing substantial resistance to X. citri subsp. citri (X. citri). We have previously shown that this cultivar has significantly lower canker incidence and severity than 'Clemenules', particularly during early stages of leaf development in the field. This differential response is only seen when the leaves are inoculated by spraying, suggesting that leaf surface contributes to resistance. In this work, we have studied structural and chemical properties of leaf surface barriers of both cultivars. Ultrastructural analysis showed a thicker cuticle covering epidermal surface and guard cells in young 'Okitsu' leaves than in 'Clemenules'. This thicker cuticle was associated with a smaller stomatal aperture and reduced cuticle permeability. These findings correlated with an accumulation of cuticular wax components, including primary alcohols, alkanes, and fatty acids. None of these differences were observed in mature leaves, where both cultivars are equally resistant to the bacterium. Remarkably, mechanical alteration of cuticular thickness of young 'Okitsu' leaves allows canker development. Furthermore, cuticular waxes extracted from young 'Okitsu' leaves have higher antibacterial activity against X. citri than 'Clemenules'. Taken together, these data suggest that a faster development of epicuticular waxes in 'Okitsu' leaves play a central role in its resistance to X. citri.This work was mainly supported by the Agencia Nacional de Promoción Cientifica y Tecnologica (PICT-2016-1222) to M. R. Marano, (PICT-2015-0261) to M. A. Favaro and by a Programa de Cooperacion Bilateral CONICET-CSIC PCB II 2013 to M. R. Marano and J. Gadea. M. R. Marano, M. A. Favaro, and R. A. Roeschlin are Career Investigators of CONICET; M. A. Favaro, R. A. Roeschlin, and M. C. Molina were supported by postdoctoral and doctoral scholarships from CONICET.Favaro, MA.; Molina, MC.; Roeschlin, RA.; Gadea Vacas, J.; Gariglio, N.; Marano, MR. (2020). Different Responses in Mandarin Cultivars Uncover a Role of Cuticular Waxes in the Resistance to Citrus Canker. Phytopathology. 110(11):1791-1801. https://doi.org/10.1094/PHYTO-02-20-0053-RS179118011101
Floristic patterns in Isoeto-Nanojuncetea communities on the Iberian Peninsula
Oral PresentationN/
Engegada d'un reactor anaerobi de llit de llots (UASB) per a la depuració de l'aigua residual d'una feculera
Bioactive and nutritional potential of medicinal and aromatic plant (MAP) seasoning mixtures
Medicinal and aromatic plants (MAPs), worldwide appreciated and used as condiments, dyes, and preservatives, possess several biological properties that justify their continuous application in the food industry. In the present study, the nutritional and chemical profiles, as well as the bioactive properties of four combinations of condiments, sold for seasoning poultry, meat, fish, and salads, were evaluated. Twenty-five phenolic compounds (HPLC-DAD-ESI/MS) were identified, with apigenin-O-malonyl-pentoside-hexoside as the major compound detected in all extracts. Oxalic and citric acids were identified in all mixtures (UFLC-PDA), as well as all the four tocopherol isoforms (HPLC-fluorescence). Regarding bioactivities, the mixtures for meat and salads (TBARS) and meat and poultry (OxHLIA) stood out for their antioxidant potential, whereas for the anti-inflammatory and antitumor properties, the mixtures revealing the greatest results were those for poultry and salad, respectively. In terms of antimicrobial activity, all the mixtures revealed the capacity to inhibit the growth of some bacterial strains. In brief, condiment mixtures showed to be a good source of bioactive compounds, as they confer health benefits, validating the importance of their inclusion in the human diet as a good dietary practice.The authors are grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support through national funds FCT/MCTES to CIMO (UIDB/00690/2020); national funding by F.C.T. and P.I., through the institutional scientific employment program-contract for C.P., M.I.D., R.C.C. and L.B. contracts and A.K.M. (2020.06231.BD) and M.A.-O. (2020.06297.BD) PhD
grants. To FEDER-Interreg España-Portugal programme for financial support through the project TRANSCoLAB 0612_TRANS_CO_LAB_2_P; to ERDF through the Regional Operational Program North 2020, within the scope of Project GreenHealth-Norte-01-0145-FEDER-000042.info:eu-repo/semantics/publishedVersio
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