Computer Generation of Metal Components by Simultaneous Deposition of Mould, Cores and Part

A new solid freeforming method based on co-delivery of mould powder materials and part powder materials using vibration-controlled, dry powder valves is presented in this paper. Thin layers of stainless steel powder are delivered to the forming area according to the cross-section of the CAD file to produce the component. Mould powder which has low sinterability is delivered to the non-forming areas of the same layer. All powders are delivered by computer-controlled, acoustic powder valves. The flow rate and switching of the valves provides the composition and shape control during fabrication. The stacked layers of loose powder are then sintered in a conventional furnace. The mould materials are removed after sintering. This method avoids the high thermal stress problem in selective laser sintering, avoids high capitalisation, makes use of conventional furnaces and allows for the incorporation of three dimensional function gradients. Test pieces including step wedge and Spierpinski’s cube were fabricated. Advantages, limitations and problems are discussed.Mechanical Engineerin

Prevalence of smoking among the students resided at dormitories in Golestan university of medical sciences, Iran

Introduction: Cigarette smoking leads to harmful physical and emotional problems and also is a predisposed factor for the addiction. The aim of this study was an attempt to determine the rate of prevalence and causes of smoking among the students of Golestan University of Medical Sciences who resided in the dormitories. Material & Methods: A cross-sectional analytical study conducted among the resident students of dormitories in 2010. The sample size consisted of all the university dormitory students. The data gathered using a validated and reliable questionnaire. The data analyzed using SPSS software and statistical tests including Chi-square, Logistic regression and Independent t-test. Results: Of 669 students, 538 (80%) of them filled out the questionnaires completely. 67.3% (362 subjects) were female. 6.1% (33 students) were smoker and 83.5% of them had experiences of cigarette smoking. The most important reasons for the smoking tendency were “having a smoker friend in 33%, a personal interest 27% and as hobby in 24% of the cases”. There were significant relation between “age, sex, region and year of education” with smoking (P0.05). Conclusion: The results indicated low prevalence of cigarette smoking among the students. However, preventive measures should be taken to conduit youth toward healthier behaviors. It seems parental control and monitoring children’s friend finding are crucial issue. © 2014, Bangladesh Journal of Medical Science. All rights reserved

Velocity Curve Analysis of the Spectroscopic Binary Stars V373 Cas, V2388 Oph, V401 Cyg, GM Dra, V523 Cas, AB And, and HD 141929 by Artificial Neural Networks

We used an Artificial Neural Network (ANN) to derive the orbital parameters of spectroscopic binary stars. Using measured radial velocity data of seven double-lined spectroscopic binary systems V373 Cas, V2388 Oph, V401 Cyg, GM Dra, V523 Cas, AB And, and HD 141929, we found corresponding orbital and spectroscopic elements. Our numerical results are in good agreement with those obtained by others using more traditional methods.Comment: 13 pages, 8 figures, 14 Table

Application of a New Non-Linear Least Squares Velocity Curve Analysis Technique for Spectroscopic Binary Stars

Using measured radial velocity data of nine double lined spectroscopic binary systems NSV 223, AB And, V2082 Cyg, HS Her, V918 Her, BV Dra, BW Dra, V2357 Oph, and YZ Cas, we find corresponding orbital and spectroscopic elements via the method introduced by Karami & Mohebi (2007a) and Karami & Teimoorinia (2007). Our numerical results are in good agreement with those obtained by others using more traditional methods.Comment: 6 pages, 3 figures. Accepted for publication in Astrophysics & Space Scienc

Epidemiological alteration in pathogens found in ground meat in Iran: unexpected predominance of vancomycin-resistant Enterococcus faecalis

Colonization of the human and animal intestinal tract with potential pathogenic bacteria is correlated with the risk of contamination of food products. The current study analyzed the prevalence of Enterococcus faecalis and Escherichia coli O157H7 in ground meat in Ilam, Iran. Both index organisms were identified following standard food microbiological methods. For E. faecalis, the susceptibility to vancomycin was tested, and PCR was used to check for the vanA gene. E. faecalis was present in all 24 ground meat samples, with no E. coli O157H7 detected in samples. The analysis showed the presence of the vanA gene in 5/24 vancomycin resistant enterococci. In conclusion, this study for the first time demonstrates the presence of vancomycin-resistant enterococci in ground meat in Iran. This observation warrants further epidemiologic investigation and should be followed up in the future

Laboratories risks evaluation of Persian Gulf and Oman Sea Ecological Research Center

In this study, to assess and classify risks associated with working in the laboratories of Persian Gulf and Oman Sea Ecological Research Center, the method of "Failure Mode Effects Analysis" (FMEA) as well as some statistical methods were used. The results of the risk assessment in the 11 affiliated laboratories showed that the risk levels in all cases, except for benthos laboratory, could be evaluated as moderate or high and therefore appropriate corrective actions must be implemented. Based on the results of the Kruskal-Wallis tests both before and after the corrective actions, there were significant differences between the laboratories from the viewpoint of risk priority number (RPN). The post hoc tests showed the lowest risk levels for the benthose and histology laboratories, while the highest risks identified in the laboratory of instrumental analysis. The results of the classification of the laboratories using cluster analysis are largely similar to those of the posthoc tests. According to Mann-Whitney U test, only in the case of the samples preparation laboratory, significant differences between the values of the RPN before and after the corrective actions could be observed (p> 0.05), however, the risk levels still remained high. In general it can be concluded that FMEA is an effective method for risk assessment in the research laboratories and appropriate statistical methods can also be used for complementary analysis

Cardiorenal Biomarkers, Canagliflozin, and Outcomes in Diabetic Kidney Disease: The CREDENCE Trial

BACKGROUND: People with type 2 diabetes and albuminuria are at an elevated risk for cardiac and renal events. The optimal biomarkers to aid disease prediction and to understand the benefits of sodium-glucose cotransporter-2 inhibition remain unclear. METHODS: Among 2627 study participants in the CREDENCE trial (Canagliflozin and Renal Events in Diabetes With Established Nephropathy Clinical Evaluation), concentrations of NT-proBNP (N-terminal pro-B-type natriuretic peptide), high-sensitivity cardiac troponin T, growth differentiation factor-15, and IGFBP7 (insulin-like growth factor binding protein 7) were measured. The effect of canagliflozin on biomarker concentrations was evaluated. The prognostic potential of each biomarker on the primary outcome (a composite of end-stage kidney disease [dialysis, transplantation, or a sustained estimated glomerular filtration rate of <15 mL·min-1·1.73 m-2], doubling of the serum creatinine level, or renal death or cardiovascular death) was assessed. RESULTS: The median (quartiles 1 and 3) concentration of each biomarker was generally elevated: NT-proBNP, 180 ng/L (82, 442 ng/L); high-sensitivity cardiac troponin T, 19 ng/L (12, 29 ng/L); growth differentiation factor-15, 2595 ng/L (1852, 3775 ng/L); and IGFBP7, 121.8 ng/mL (105.4, 141.5 ng/mL). At 1 year, the biomarkers all rose by 6% to 29% in the placebo arm but only by 3% to 10% in the canagliflozin arm (all P<0.01 in multivariable linear mixed-effect models). Baseline concentrations of each biomarker were strongly predictive of cardiac and renal outcomes. When the biomarkers were analyzed together in a multimarker panel, individuals with high risk scores (hazard ratio [HR], 4.01 [95% CI, 2.52-6.35]) and moderate risk scores (HR, 2.39 [95% CI, 1.48-3.87]) showed a higher risk for the primary outcome compared with those with low risk scores. By 1 year, a 50% increase in NT-proBNP (HR, 1.11 [95% CI, 1.08-1.15]), high-sensitivity cardiac troponin T (HR, 1.86 [95% CI, 1.64-2.10]), growth differentiation factor-15 (HR, 1.45 [95% CI, 1.24-1.70]), and IGFBP7 (HR, 3.76 [95% CI, 2.54-5.56]) was associated with risk of the primary outcome. CONCLUSIONS: Multiple cardiorenal stress biomarkers are strongly prognostic in people with type 2 diabetes and albuminuria. Canagliflozin modestly reduced the longitudinal trajectory of rise in each biomarker. Change in the biomarker level in addition to the baseline level augments the primary outcome prediction. REGISTRATION: URL: https://www. CLINICALTRIALS: gov; Unique identifier: NCT02065791

Characterization of antimicrobial resistance pattern and molecular analysis among extended spectrum β-lactamase-producing Escherichia coli

Background: Infection is a serious problem in medicine and appropriate antibiotic therapy is very important. Because of broad spectrum activity and low toxicity of β-lactam antibiotics, they are the most commonly used drugs. But, bacterial resistance to β-lactam antibiotics, has been considered as the global healthcare concern. The aim of study was to evaluate the antimicrobial resistance pattern and molecular characterization among ESBL-producing Escherichia coli isolated from patients with diarrhea admitted to a hospital in Ilam, Iran. Methods: Totally, fifty E. coli isolates were investigated. Confirmatory tests for phenotypic detection of ESBLs were performed. Molecular identification of the blaTEM and blaSHV genes was carried out by PCR method. To identify genetic relatedness among isolates, Randomly Amplified Polymorphic DNA (RAPD) analysis was performed. Results: The antibiotic susceptibility results showed that the most effective antibiotic was imipenem and minimum effect was related to gentamicin. Thirty-one isolates (62) were ESBL-producing organisms according to phenotypic method. The distribution of blaTEM and blaSHV genes among ESBL-producing isolates were 20 (64.5) and 6 (19.3), respectively. RAPD-PCR typing among isolates gave us eight different types. Twelve isolates were clustered in genotype A and all of them were ESBL-producer. Conclusion: The present study showed noticeable incidence of ESBL-producing E. coli isolated from outpatients and hospitalized patients with diarrhea. Therefore, it seems that constant supervision is crucial to monitor the ESBL-producing microorganisms in hospitals and community. © 2016 The Authors

Production of Artemia in Fesendoz earthpond

In order to optimal using of constructed earthpond in fesendoz area which in not used for the maine objective (warm water fish culture) because of previous drought years, the possibility of them for Artemia culture with drainage (40 ppt) and salin well (90ppt) waters between 2012-13 were evaluated. In the first year 2 ha and in the second year 7 ha were prepared according to standard method and artemia nauplii were released 60 /L then fertilized with fertilization method in order to obtain 40 cm transparency with using sechi disc. After reaching to adalt stage and in order to fertilization management Artemai biomass were harvested daily 300 to 1000 g base of the early and late production periods. After observed the cysts it gathered by using sachok, proccess and maintain in freezer for stopping diapousthen dried and canned in 330g can with 7±1 % humidity. All the production costs for biomass 100000 Rials and for cyst 1800000 rials while they selling 250000 rials and 2500000 Rilas respectively