UTP e-Mart

Because oflthe hassle, an e-Mart is going to be developed which is an e-connnerce website that is going to sell goods to the UTP students, and have the goods ordered delivered to the students' doorstep. This website will help ease the students to buy goods without having to go outside of UTP campus. The website will sell products that are actually frolfl the brick-and-mortar stores that most students go to, to buy goods. Students can make orders, and have the goods delivered. Finding the market owners will be a challqnge, as this will be on online orders. The website will act as the intermediaries between the market and the students to make a purchase. The website will be the first one to be introduced in UTP that able the students to buy goods online. This report explains the progress of building the system where all the aspects involves explained in the result and discussion part of this text. The objective of this section states all the progress of building the system. It also researches on the online grocery shopping and also the Systems Analysis and Design of the Systems Development Life Cycle (SDLC). The methodology and also the findings from the SDLC are also discussed. There is also feasibility study that consists of three aspects to look into which are the operational study, technical study and also the economic study. The whole document discusses the progress of building the system where all the aspects involved are explained in the result and discussion part of this text

UTP e-Mart

Because oflthe hassle, an e-Mart is going to be developed which is an e-connnerce website that is going to sell goods to the UTP students, and have the goods ordered delivered to the students' doorstep. This website will help ease the students to buy goods without having to go outside of UTP campus. The website will sell products that are actually frolfl the brick-and-mortar stores that most students go to, to buy goods. Students can make orders, and have the goods delivered. Finding the market owners will be a challqnge, as this will be on online orders. The website will act as the intermediaries between the market and the students to make a purchase. The website will be the first one to be introduced in UTP that able the students to buy goods online. This report explains the progress of building the system where all the aspects involves explained in the result and discussion part of this text. The objective of this section states all the progress of building the system. It also researches on the online grocery shopping and also the Systems Analysis and Design of the Systems Development Life Cycle (SDLC). The methodology and also the findings from the SDLC are also discussed. There is also feasibility study that consists of three aspects to look into which are the operational study, technical study and also the economic study. The whole document discusses the progress of building the system where all the aspects involved are explained in the result and discussion part of this text

Evaluation of kenaf yarn properties as affected by different linear densities for woven fabric laminated composite production

Currently, there is a growing interest of using woven material in composite production for many applications such as structural applications, non-structural applications, household utilities, parts for automobile, aerospace components, flooring and ballistic laminate composites. The structure and properties of the woven fabric is very important as it dictate the woven composite properties. The properties of yarn like linear density, twist factor and strength can influence most of the woven fabric properties. Strength of woven fabric is one of the most important properties which make it superior in final composite applications. In this study, the effects of linear density i.e. 500, 1000, 1500 and 2000 tex on physical and mechanical properties of kenaf yarn were evaluated. The assessment on twist type, twist angle, yarn diameter, yarn structure, fibre density, moisture content, water absorption and mechanical properties were carried out on kenaf yarns. The yarn mechanical properties were tested on the tensile strength, Young’s Modulus and elongation. It was found that, different linear density of yarn exhibited different behavior of yarn properties. Higher linear density yarn produced wider yarn diameter compared to lower linear density yarn, resulting to higher fibre and moisture content yarn. Yarn tensile strength has increased by 46% when linear density was changed from 500 to 2000 tex due to higher amount of individual fibres. However, for Young’s Modulus, the values reduced as the yarn linear density increased due to several factors including number of fibres and moisture content of yarn

Evaluation of kenaf yarn properties as affected by different linear densities for woven fabric laminated composite production

Currently, there is a growing interest of using woven material in composite production for many applications such as structural applications, non-structural applications, household utilities, parts for automobile, aerospace components, flooring and ballistic laminate composites. The structure and properties of the woven fabric is very important as it dictate the woven composite properties. The properties of yarn like linear density, twist factor and strength can influence most of the woven fabric properties. Strength of woven fabric is one of the most important properties which make it superior in final composite applications. In this study, the effects of linear density i.e. 500, 1000, 1500 and 2000 tex on physical and mechanical properties of kenaf yarn were evaluated. The assessment on twist type, twist angle, yarn diameter, yarn structure, fibre density, moisture content, water absorption and mechanical properties were carried out on kenaf yarns. The yarn mechanical properties were tested on the tensile strength, Young’s Modulus and elongation. It was found that, different linear density of yarn exhibited different behavior of yarn properties. Higher linear density yarn produced wider yarn diameter compared to lower linear density yarn, resulting to higher fibre and moisture content yarn. Yarn tensile strength has increased by 46% when linear density was changed from 500 to 2000 tex due to higher amount of individual fibres. However, for Young’s Modulus, the values reduced as the yarn linear density increased due to several factors including number of fibres and moisture content of yarn

The effect of yarn linear density on mechanical properties of plain woven kenaf reinforced unsaturated polyester composite

To produce a good quality of dry fabric for reinforced material in a natural-based polymer composite, yarn linear density should be in consideration. A woven kenaf dry fabric with three different linear densities of 276tex, 413.4tex and 759tex were produced. The fabrics with different linear densities were been optimize with the assistance of WiseTex software. The optimized dry fabrics were infused with unsaturated polyester to produce composite panel using vacuum infusion process. The composites properties were tested on the tensile strength, flexural strength and the impact strength. The result shows that the mechanical properties of the composite increased when the yarn linear densities increased

The effect of alkali treatment on impact strength of woven kenaf reinforced unsaturated polyester composite using vacuum infusion process

Nowadays, natural fibres are used in many applications such as automotive, due to its material properties and being environmental friendly. This study is on woven Kenaf reinforced unsaturated polyester focusing on the effect of alkali treatment towards the impact strength of the textile composite. The experiment consists of two different yarn size woven in plain weave and infused using vacuum infusion process into a composite panel. Optic microscopy was used to determine the swelling of fibre, fabrics and composites before and after alkali treatment. The high speed puncture was used to evaluate the impact strength of pure unsaturated polyester and the composite. The results showed that alkali treatment enhanced the impact strength of the composite compared to pure polyester and untreated composite. The swelling of the fibres caused the yarns to expand throughout the thickness and the width of each composite. The gap between the yarns interlacing was reduced due to the expansion of yarns which has increased the covering area of the reinforced material

The effect of alkaline treatment on tensile strength and morphological properties of kenaf fibres for yarn production

This paper investigates the effect of alkali treatment and mechanical properties of kenaf (Hibiscus cannabinus)fibre for the development of yarn. Two different fibre sources are used for the yarn production. Kenaf fibres were treated with sodium hydroxide (NaOH) in the concentration of 3, 6, 9, and 12% prior to fibre opening process and tested for their tensile strength and Young’s modulus. Then, the selected fibres were introduced to fibre opener at three different opening processing parameters; namely, speed of roller feeder, small drum, and big drum. The diameter size, surface morphology, and fibre durability towards machine of the fibres were characterized. The results show that concentrations of NaOH used have greater effects on fibre mechanical properties. From this study, the tensile and modulus properties of the treated fibres for both types have improved significantly as compared to untreated fibres, especially at the optimum level of 6% NaOH. It is also interesting to highlight that 6% NaOH is the optimum concentration for the alkaline treatment. The untreated and treated fibres at 6% NaOH were then introduced to fibre opener, and it was found that the treated fibre produced higher fibre diameter with better surface morphology compared to the untreated fibre. Higher speed parameter during opening was found to produce higher yield of opened-kenaf fibres

Synthesis, modelling and kinetic assays of potent inhibitors of purple acid phosphatase

Purple acid phosphatases (PAPs) are binuclear metallohydrolases that have been isolated from various mammals, plants, fungi and bacteria. In mammals PAP activity is associated with bone resorption and can lead to bone metabolic disorders such as osteoporosis; thus human PAP is an attractive target to develop anti-osteoporotic drugs. Based on a previous lead compound and rational drug design, acyl derivatives of alpha-aminonaphthylmethylphosphonic acid were synthesised and tested as PAP inhibitors. Kinetic analysis showed that they are good PAP inhibitors whose potencies improve with increasing acyl chain length. Maximum potency is reached when the number of carbons in the acyl chain is between 12 and 14. The most potent inhibitor of red kidney bean PAP is the dodecyl-derivative with K-ic = 5 mu M, while the most potent pig PAP inhibitor is the tetradecyl-derivative with K-ic = 8 mu M, the most potent inhibitor of a mammalian PAP yet reported. Crown Copyright (C) 2011 Published by Elsevier Ltd. All rights reserved

Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics

Purple acid phosphatases are metalloenzymes found in animals, plants and fungi. They possess a binuclear metal centre to catalyse the hydrolysis of phosphate esters and anhydrides under acidic conditions. In humans, elevated purple acid phosphatases levels in sera are correlated with the progression of osteoporosis and metabolic bone malignancies, making this enzyme a target for the development of new chemotherapeutics to treat bone-related illnesses. To date, little progress has been achieved towards the design of specific and potent inhibitors of this enzyme that have drug-like properties. Here, we have undertaken a fragment-based screening approach using a 500-compound library identifying three inhibitors of purple acid phosphatases with Ki values in the 3060 mu m range. Ligand efficiency values are 0.390.44 kcal/mol per heavy atom. X-ray crystal structures of these compounds in complex with a plant purple acid phosphatases (2.32.7 angstrom resolution) have been determined and show that all bind in the active site within contact of the binuclear centre. For one of these compounds, the phenyl ring is positioned within 3.5 angstrom of the binuclear centre. Docking simulations indicate that the three compounds fit into the active site of human purple acid phosphatases. These studies open the way to the design of more potent and selective inhibitors of purple acid phosphatases that can be tested as anti-osteoporotic drug leads