81 research outputs found
Teachersâ Perceptions about Language Learning Difficulties in English as a Foreign Language EFL Classes
The research aimed at verifying English language teachers' perceptions about English language learning difficulties in their classes. Using a descriptive analytical approach, it utilized a questionnaire which included (60) items which were divided over four parts; the first was about the basic concepts, the second was about the intervention techniques, the third included class barriers while the fourth was about class assessment techniques. The second instrument is an online reflection journal to record participants' views about language learning difficulties. The participants (N. 99) were English language teachers from different stages at The Red Sea Governorate in Egypt. Following a descriptive analytical research design, the research utilized the instruments to record the results and interpret them in the light of its hypotheses. Results showed that there was a strong correlation between participants' concepts over the four parts of the questionnaire (basic concepts, intervention techniques, class barriers and assessment techniques. Results also showed that there were significant mean differences between participant's scores in the four parts of the questionnaire favoring the concepts part. Recommendations of the research included integrating language learning difficulties modules in both pre-service and in-service teachersâ education and training programs as well as highlighting intervention techniques in EFL curricula as well as LD assessment procedures and techniques
Rock Mass Fracture Detection and Modelling Using GPR for Evaluation and Production Optimization of Ornamental Stone Deposits
The thesis presents new solutions for the fractures problem in ornamental stone quarries which entails economic and material loses. The thesis aimed at developing methodologies and providing solutions for evaluation and production optimization of ornamental stone deposits. Ground Penetrating Radar (GPR) was selected, among several methods, as a fracture detection tool for this research. A combination of the use of a low frequency GPR antenna and laboratory rock tests for evaluation of an ornamental stone deposit showed encouraging results. Based on GPR survey, particularly high frequency antennas, a 3D deterministic fracture modeling approach was developed and implemented in several case studies of block and bench scales. A fracture index was proposed for deposit evaluation based on fracture detections from GPR survey. Additionally, an in-situ GPR test allowed formulating a propagation velocity model for 3D mapping of the dielectric constant of the medium, within macro and micro scale of the rock mass of a bench in a sandstone quarry. This finding is significant for future improvement of the deterministic accuracy level of the developed fracture modeling approach and, generally, for the GPR applications in rock mass. Regarding quarrying optimization, two 3D algorithms, based on fracture modeling or mapping, were developed for production and/or revenue optimization of cutting slabs from blocks and cutting blocks from benches. The algorithms were coded in two software packages named SlabCutOpt and BlockCutOpt. SlabCutOpt was applied to a case study of a limestone block through testing 37 different commercial-sizes of slabs, investigating the optimization results in terms of recovery ratio (a geo-environmental direction) and revenue (an economic direction). BlockCutOpt was applied to two case studies (quarries) with different site characteristics. The results showed that optimum cutting direction of blocks can vertically and horizontally vary, giving geometric information about the cutting grid of blocks that optimizes the production
Interferon therapy shifts natural killer subsets among Egyptian patients with chronic hepatitis C
AbstractNatural killer cells can be divided into five subpopulations based on the relative expression of CD16 and CD56 markers. The majority of natural killer cells are CD56dim, which are considered to be the main cytotoxic effectors. A minority of the natural killer cells are CD56bright, and function as an important source of immune-regulatory cytokines. Shifts of these subsets have been reported in patients with chronic hepatitis C virus infection. We sought to investigate the shift of natural killer subsets among Egyptian patients with chronic HCV and to analyze the influence of interferon therapy on this shift. We applied a flow cytometric analysis of peripheral blood natural killer subsets for 12 interferon-untreated and 12 interferon-treated patients with chronic HCV, in comparison to 10 control subjects. Among interferon-untreated patients, there was a significant reduction of CD56-16+ (immature natural killer) cells. Among interferon-treated patients, the absolute count of natural killer cells was reduced, with expansion of the CD56bright subset and reduction of the CD56dim16+ subset. Natural killer subset counts were not significantly correlated to HCV viral load and were not significantly different among interferon responders and non-responders. In conclusion, HCV infection in Egyptian patients has been observed to be statistically and significantly associated with reduction of the CD56-16+NK subset, while a statistically significant expansion of CD56bright and reduction of CD56dim16+ subsets were observed after interferon therapy. Further studies are required to delineate the molecular basis of interferon-induced shift of natural killer subsets among patients with HCV
Clinical Assessment of the Efficiency of Low Level Laser Therapy in the Treatment of Oral Lichen Planus
BACKGROUND: Oral lichen planus (OLP) is a chronic inflammatory disease of the oral mucosa of uncertain etiology.AIM: To evaluate the effect of using low level laser therapy (LLLT (970 nm Siro laser Advance) for the treatment of symptomatic (OLP).SUBJECTS AND METHODS: The present study was conducted on ten patients suffering from persistent oral lichen planus (OLP).Patients were treated with diode laser (970nm) for the symptomatic relief of pain and burning sensation. The patients were assessed before, during and after the completion of the laser treatment which was done twice weekly for two successive months with maximum of ten sessions. The assessment was performed using visual analogue scale (VAS) and clinical investigation for each patient.RESULTS: Detailed significant reduction in lesion size and showed complete remission of burning sensation and pain. No reported complications or therapy side effects were observed in any of the treated patients.CONCLUSION: Diode laser therapy seems to be an effective adjunctive treatment modality for relieving pain and clinical symptoms of OLP
The effect of diode laser and topical steroid on serum level of TNF-alpha in oral lichen planus patients
Oral lichen planus (OLP) is a common chronic inflammatory mucosal disease with a multifactorial etiology. It is a T-cell mediated autoimmune disease in which the cytotoxic CD8+T cells trigger apoptosis of the basal cells of oral epithelium. Various treatment regimens have been employed for management of symptomatic OLP. This study was carried out to evaluate the effect of topical steroids as well as laser on the clinical signs and symptoms detected by reticular, atrophic, erosive score (RAE score) and tumor necrosis factor- α (TNF-α) level in the serum of patients with symptomatic OLP.
The study was conducted on twenty-four patients (18 females and 6 males) with symptomatic OLP that were allocated into two groups. Each included twelve patients. The first group treated either with diode laser (970nm SIROLaser Advance class IIIb, SIRONA The Dental Company, Germany) twice weekly with maximum of ten sessions while the second group were treated with topical corticosteroids (0.1% triamcinolone acetonide orabase, Kenacort-A Orabase Pomad, DEVA HOLDING A.È, Istanbul, Turkey) for four weeks.
Corticosteroids group showed less clinical signs and symptoms of reticular, atrophic, erosive RAE score (p=0.02) and TNF-α serum level (p=0.028) than diode laser group with no reported therapy side effects or complications in any of the treated patients.
Topical steroids reduce pain, reticular, atrophic, erosive RAE score and TNF-α serum level more than laser treatment. Moreover, laser treatment can be used as an alternative treatment when steroids are contraindicated for the treatment of symptomatic OLP
Plasma soluble CD 163 level as a marker of oesophageal varices in cirrhotic patients
Background: Variceal bleeding (VB), the most common lethal complication of cirrhosis, associated with high mortality. Timely prediction of esophageal varices (EV) represents a real challenge for the medical team. This study evaluated the level of plasma soluble CD 163 as a marker of the presence of EVs and to compare it with other noninvasive clinical, laboratory and ultrasonographic parameters as well as endoscopy.Methods: This prospective controlled study was conducted on 80 adults. Gp I had no oesophageal varices, gp II had small varices, gp IIIa had large varices, gp IIIb are the same patients of gp IIIa but after eradication of varices and gp IV as healthy controls. Serum samples were assayed for soluble CD 163.Results: soluble CD163 was statistically significant different between controls and all liver cirrhosis. it showed a statistically significant difference between group I and II (p = 0.009) and between group I and IIIa (p < 0.001) and between group II and IIIa (p < 0.001) but, no difference between group IIIa and IIIb (p = 0.179).Conclusion: Serum soluble CD163 is a good noninvasive predictor for the presence of EVs and it may be used for grading of EVs. Its level does not change after esophageal varices eradication.Trial registration: IRB No: 00007589 FWA No: 00015712 The Ethics Committee of the faculty of medicine Alexandria University.Keywords: Hepatic, Cirrhosis, Varices, CD163, Endoscopy, Ultrasonograph
Lean partially premixed turbulent flame equivalence ratio measurements using laser-induced breakdown spectroscopy
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.The creation of a more stable flame along with the extension of flammability limits under lean mixture combustion was the main motivation to develop a new burner design, which has been investigated in this research. The current burner configuration was utilized to create a wide range of higher turbulent intensities and to produce different degrees of mixture inhomogeneity, which acted to promote minimum pollution, highest performance and higher flame stability. The burner stability assessment was investigated using two types of fuel: natural gas (NG) and liquefied petroleum gas (LPG). They were tested under different degrees of partial premixing, and two turbulence generator disks for lean mixture at an equivalence ratio of ÏâŻ=âŻ0.8 were used. Following this, the Laser Induced Breakdown Spectroscopy (LIBS) technique was utilized to characterize and quantify the impact of changing the disk slit diameter on the distributions profiles of equivalence ratio or mixture fraction for a NG/air partially premixed flame. A series of homogeneous NG/air mixtures with different equivalence ratios were used to obtain the correlations between the measured emission lines of LIBS spectra and the global flame equivalence ratio. Consequently, the emission spectral lines ratios of H/N, H/O and C/NâŻ+âŻO were utilized to predict the equivalence ratio distributions. The results demonstrated that for all of the mixing lengths, NG/air mixture with larger disk generator diameter yielded the maximum burner stability, whilst the LPG/air mixture with a larger disk generator diameter resulted in the minimum burner stability. Furthermore, the flame associated with the larger disk slit diameter had a uniform local equivalence ratio distribution and lower RMS fluctuation profiles of equivalence ratio in comparison to the lower disk slit diameter
Erectile Dysfunction in Hemodialysis Patients in Fayoum (Egypt)
Erectile dysfunctio
Diagnostic efficacy of monoclonal antibody based sandwich enzyme linked immunosorbent assay (ELISA) for detection of Fasciola gigantica excretory/secretory antigens in both serum and stool
<p>Abstract</p> <p>Background</p> <p>This research was carried out to develop a reliable monoclonal antibody (MoAb)-based sandwich enzyme linked immunosorbent assay (ELISA) for the diagnosis of active <it>Fasciola gigantica </it>infection in both serum and stool for comparative purposes.</p> <p>Methods</p> <p>From a panel of MoAbs raised against <it>F. gigantica </it>excretory/secretory antigens (ES Ags), a pair (12B/11D/3F and 10A/9D/10G) was chosen due to its high reactivity and strict specificity to <it>F. gigantica </it>antigen by indirect ELISA.</p> <p>Results</p> <p>The two MoAbs were of the IgG<sub>1 </sub>and IgG<sub>2a </sub>subclasses, respectively. Using SDS-PAGE and EITB, the selected MoAbs recognized 83, 64, 45 and 26 kDa bands of ES Ags. The lower detection limit of ELISA assay was 3 ng/ml. In stool, the sensitivity, specificity and diagnostic efficacy of ELISA was 96%, 98.2 and 97.1%; while in serum they were 94%, 94.6% and 94.3%, respectively. Moreover, a positive correlation was found between ova count in stool of <it>F. gigantica </it>infected patients and the OD readings of ELISA in both stool and serum samples (<it>r </it>= 0.730, p < 0.01 and r = 0.608; p < 0.01, respectively).</p> <p>Conclusions</p> <p>These data showed that the use of MoAb-based sandwich ELISA for the detection of <it>F. gigantica </it>coproantigens in stool specimens was superior to serum samples; it provides a highly efficient, non-invasive technique for the diagnosis of active <it>F. gigantica </it>infection.</p
- âŠ