Frontal brain asymmetries as effective parameters to assess the quality of audiovisual stimuli perception in adult and young cochlear implant users

How is music perceived by cochlear implant (CI) users? This question arises as "the next step" given the impressive performance obtained by these patients in language perception. Furthermore, how can music perception be evaluated beyond self-report rating, in order to obtain measurable data? To address this question, estimation of the frontal electroencephalographic (EEG) alpha activity imbalance, acquired through a 19-channel EEG cap, appears to be a suitable instrument to measure the approach/withdrawal (AW index) reaction to external stimuli. Specifically, a greater value of AW indicates an increased propensity to stimulus approach, and vice versa a lower one a tendency to withdraw from the stimulus. Additionally, due to prelingually and postlingually deafened pathology acquisition, children and adults, respectively, would probably differ in music perception. The aim of the present study was to investigate children and adult CI users, in unilateral (UCI) and bilateral (BCI) implantation conditions, during three experimental situations of music exposure (normal, distorted and mute). Additionally, a study of functional connectivity patterns within cerebral networks was performed to investigate functioning patterns in different experimental populations. As a general result, congruency among patterns between BCI patients and control (CTRL) subjects was seen, characterised by lowest values for the distorted condition (vs. normal and mute conditions) in the AW index and in the connectivity analysis. Additionally, the normal and distorted conditions were significantly different in CI and CTRL adults, and in CTRL children, but not in CI children. These results suggest a higher capacity of discrimination and approach motivation towards normal music in CTRL and BCI subjects, but not for UCI patients. Therefore, for perception of music CTRL and BCI participants appear more similar than UCI subjects, as estimated by measurable and not self-reported parameters

A study of methyl formate in astrochemical environments

Several complex organic molecules are routinely detected in high abundances towards hot cores and hot corinos. For many of them, their paths of formation in space are uncertain, as gas phase reactions alone seem to be insufficient. In this paper, we investigate a possible solid-phase route of formation for methyl formate (HCOOCH3). We use a chemical model updated with recent results from an experiment where simulated grain surfaces were irradiated with 200 keV protons at 16 K, to simulate the effects of cosmic ray irradiation on grain surfaces. We find that this model may be sufficient to reproduce the observed methyl formate in dark clouds, but not that found in hot cores and corinos.Comment: 6 pages, 2 figures, 2 tables Accepted by MNRA

Droplet minimizers for the Gates-Lebowitz-Penrose free energy functional

We study the structure of the constrained minimizers of the Gates-Lebowitz-Penrose free-energy functional ${\mathcal F}_{\rm GLP}(m)$, non-local functional of a density field $m(x)$, $x\in {\mathcal T}_L$, a $d$-dimensional torus of side length $L$. At low temperatures, ${\mathcal F}_{\rm GLP}$ is not convex, and has two distinct global minimizers, corresponding to two equilibrium states. Here we constrain the average density L^{-d}\int_{{\cal T}_L}m(x)\dd x to be a fixed value $n$ between the densities in the two equilibrium states, but close to the low density equilibrium value. In this case, a "droplet" of the high density phase may or may not form in a background of the low density phase, depending on the values $n$ and $L$. We determine the critical density for droplet formation, and the nature of the droplet, as a function of $n$ and $L$. The relation between the free energy and the large deviations functional for a particle model with long-range Kac potentials, proven in some cases, and expected to be true in general, then provides information on the structure of typical microscopic configurations of the Gibbs measure when the range of the Kac potential is large enough

Gold amides as anticancer drugs: synthesis and activity studies

Modular gold amide chemotherapeutics: Access to modern chemotherapeutics with robust and flexible synthetic routes that are amenable to extensive customisation is a key requirement in drug synthesis and discovery. A class of chiral gold amide complexes featuring amino acid derived ligands is reported herein. They all exhibit in vitro cytotoxicity against two slow growing breast cancer cell lines with limited toxicity towards normal epithelial cells

Reverse Electrodialysis with saline waters and concentrated brines: a laboratory investigation towards technology scale-up

The use of concentrated brines and brackish water as feed solutions in reverse electrodialysis represents a valuable alternative to the use of river/sea water, allowing the enhancement of power output through the increase of driving force and reduction of internal stack resistance. Apart from a number of theoretical works, very few experimental investigations have been performed so far to explore this possibility. In the present work, two RED units of different size were tested using artificial saline solutions. The effects of feed concentration, temperature and flowrate on process performance parameters were analysed, adopting two different sets of membranes. These experiments allowed to identify the most favourable conditions for maximising the power output within the presently investigated range, i.e. 0.1 M NaCl as diluate and 5 M NaCl as concentrate at 40°C. Under these conditions a power density equal to 12 W/m2cell_pair was reached, among the highest so far reported in the literature. Increasing the unit size a slight reduction in power density was observed. These results indicate new directions for a successful scale-up and development of the Reverse Eletrodialysis technology

Symmetry of Traveling Wave Solutions to the Allen-Cahn Equation in \Er^2

In this paper, we prove even symmetry of monotone traveling wave solutions to the balanced Allen-Cahn equation in the entire plane. Related results for the unbalanced Allen-Cahn equation are also discussed

DigiArt: towards a virtualization of Cultural Heritage

DigiArt is a Europe-wide project aimed at providing a new, cost efficient solution to the capture, processing and display of cultural artefacts. The project will change the ways in which the public interact with cultural objects and spaces in a dramatic way. This project is unique in its collaborative approach: cultural heritage professionals working directly with electrical, mechanical, optical and software engineers to develop a solution to current issues faced by the museum sector. The innovations created by the engineers are driven by the demand of the cultural heritage sector. The diversity of the objects and spaces of the three test museums are challenging the engineers to provide a tool useful for a broad variety of indoor and outdoor museums in the future. This goes from using Unmanned Aerial Vehicle (UAVs or drones) to fly and record large sites, to using scanners to record fine jewellery. As a case study, we present here the use-case of Scladina Cave. At the end of the project, the Scladina Cave Archaeological Centre will offer two different visitor experiences. The first uses virtual reality, which will be available anytime, anywhere, to anyone with an internet connected device. The second will use augmented reality technologies within the cave site. The augmented reality visit of the cave will enhance the tour of Scladina by offering visits that would not be possible where it not for the augmented reality, where 3D objects and animations will contribute to offer a new 3D-immersive experience

On the structure of phase transition maps for three or more coexisting phases

This paper is partly based on a lecture delivered by the author at the ERC workshop "Geometric Partial Differential Equations" held in Pisa in September 2012. What is presented here is an expanded version of that lecture.Comment: 23 pages, 6 figure

Off-nuclear star formation and obscured activity in the luminous infrared galaxy NGC 2623

New optical Hubble Space Telescope (HST), Spitzer Space Telescope, and XMM observations of the luminous infrared galaxy (LIRG) NGC 2623 are presented. This galaxy was observed as part of the Great Observatories All-sky LIRG Survey (GOALS). The prominent 3.2 kpc southern extension to the nucleus has been resolved by HST observations into ~100 star clusters, making it one of the richest off-nuclear concentrations of bright clusters observed in GOALS. The clusters have M_(F555W) ~-6.6 to -12.6 mag, which is within the magnitude range of Antennae galaxy clusters and in excess of 30 Doradus clusters at the high end. Their optical colors are primarily consistent with ages of ~1–100 Myr. Archival GALEX data show the off-nuclear region to be extremely bright in the far-ultraviolet, being equivalent in luminosity to the resolved nuclear region at 0.15 µm, but becoming less energetically significant at increasing wavelengths. In addition, [Ne v] 14.3 µm emission is detected with Spitzer IRS, confirming the inference from the X-ray and radio data that an active galactic nucleus (AGN) is present. Thus, the off-nuclear optical clusters are associated with a secondary burst of activity corresponding to a star formation rate ~0.1–0.2 M⊙ yr^(-1); the bulk of infrared (and thus bolometric) luminosity is generated via star formation and an AGN embedded behind dust within the inner kiloparsec of the system. If the infrared luminosity is primarily reprocessed starlight, the off-nuclear starburst accounts for <1% of the present star formation in NGC 2623

e-MERLIN and VLBI observations of the luminous infrared galaxy IC883: a nuclear starburst and an AGN candidate revealed

The high star formation rates of luminous infrared galaxies (LIRGs) make them ideal places for core-collapse supernova (CCSN) searches. At radio frequencies, free from dust extinction, it is possible to detect compact components within the innermost LIRG nuclear regions, such as SNe and SN remnants, as well as AGN buried deep in the LIRG nuclei. We studied the LIRG IC883 aiming at: (i) investigating its (circum-)nuclear regions using the e-EVN at 5GHz, and e-MERLIN at 6.9GHz, complemented by archival VLBI data; (ii) detecting at radio frequencies the two recently reported circumnuclear SNe 2010cu and 2011hi, which were discovered by near-IR (NIR) adaptive optics observations of IC883; and (iii) further investigating the nature of SN2011hi at NIR by means of observations with Gemini-North. The circumnuclear regions traced by e-MERLIN at 6.9GHz have an extension of ~1kpc, and show a striking double-sided structure, which very likely corresponds to a warped rotating ring, in agreement with previous studies. Our e-EVN observations at 5GHz and complementary archival VLBI data at 5GHz and 8.4GHz, reveal the presence of various milliarcsec compact components in the nucleus of IC883. A single compact source, an AGN candidate, dominates the emission at both nuclear and circumnuclear scales, as imaged with the e-EVN and e-MERLIN, respectively. The other milliarcsec components are very suggestive of ongoing nuclear CCSN activity. Our e-EVN observations also resulted in upper limits to the radio luminosity of the two SNe in IC883 recently discovered at NIR. We refine the classification of SN2011hi as a Type IIP SN according to our latest Gemini-North epoch from 2012, in agreement with a low-luminosity radio SN nature. We estimate a CCSN rate lower limit of 1.1_{-0.6}^{+1.3} yr^{-1} for the entire galaxy, based on three nuclear radio SNe and the circumnuclear SNe 2010cu and 2011hi. (abridged)Comment: 9 pages, 5 figures and 2 tables. Accepted for publication in A&