365 research outputs found

    Le Messager: A Franco-American Newspaper and its Impact

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    I grew up in Lewiston as a Franco-American on both sides of my family. My heritage has always been a fascination of mine. Anyone who studies Franco-Americans can’t help but notice that there is a striking sense of what it means to be a part of the big-C Community. Franco Americans are good Catholics, their work ethic is unmatched, families are generally on the large side, and they generally vote Democrat (this is changing a bit, but historically is the case). This social order is well known to those in the community. The idea that Francos have a strongly bonded sense of identity has been well established in the realm of Franco-American Studies. Historians like Mark Paul Richard in his book Loyal But French have done an extensive amount of research and come to this conclusion. What I want to know, though, is what caused this to happen? After doing my undergraduate thesis seminar in the history of written media, I believe that the newspaper Le Messager from Lewiston had a heavy part to play in forging this sense of identity and homogeneity for the community. In order to prove this point, I’m going to try to prove to you three things: That this newspaper was an integral source of information dissemination within the community, that the Francos really did have the overt sense of identity and homogeneity that I think they do, and that the paper consciously pushed this sense of identity on the community. To do this, I’m going to try to focus mostly on the early 20th century, an era which I believe saw the full force of this identity movement

    Encontros Telemáticos do Sudeste do Deserto Americano

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    Telematic Encounters From the American Desert Southwest recounts the early experiences in distance performance at Arizona State University leading up to the Cellbytes 2000 project, the formation of ADaPT, the Association of Dance and Performance Telematics, and other international collaborations.Encontros Telemáticos do Sudeste do Deserto Americano narra as primeiras experiências em performance a distância da Arizona State University, que antecederam o projeto Cellbytes 2000, a formação da ADaPT – Association of Dance and Performance Telematics (Associação de Dança e Performance Telemática e de outras colaborações internacionais

    Unstable Identities: The European Court of Human Rights and the Margin of Appreciation

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    All legal systems work under a master narrative – the self-conception of most actors of the system itself. A master narrative is a short and simple story and it is the underlying premise upon which any legal system is based. It is a simple story because it paints the system in quick broad brushstrokes and at (most) times is oblivious to the paradoxes within it. Furthermore, a master narrative is important for legitimization purposes because the actors’ legitimacy will depend on their (perceived) conformity with the system’s master narrative. Therefore, legitimacy is self-referential; the yardsticks for a legitimate action are contained within the system’s master narrative, not outside of it. When talking about different international courts it is important to remember that they are embedded within a master narrative that is contextual and contingent and, at different points, more or less contested. This paper explores the question of what happens when the master-narrative is in a period of transition (from a state cantered to a post-national world order) and when the actors’ legitimacy, their interpretative endeavours the very fundamentals are in a state of flux. I use the margin of appreciation discussion as a focal point of describing the conflicting narratives under which the European Court of Human Rights works, narratives in which the different actors (judges, attorneys, NGO activists, government agents) and their consequences in terms of the interpretation of the European Convention on Human Rights

    An Investigation of Four Wings of Square Plan Form at a Mach Number of 6.9 in the Langley 11-inch Hypersonic Tunnel

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    The results of pressure-distribution and force tests of four wings at a Mach number of about 6.9 and a Reynolds number of 0.98 x 10(6) in the Langley 11-inch hypersonic tunnel are presented. The wings had a square plan form, a 5-percent-chord maximum thickness, and diamond, half-diamond, wedge, and half-circular sections

    Birc2/Iap1 regulates endothelial cell integrity and blood vessel homeostasis.

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    none4noneM. SANTORO; TEMESGEN SAMUEL; TRACY MITCHEL; JOHN C. REED AND DIDIER Y. STAINIERSantoro, Massimo; Temesgen, Samuel; Tracy, Mitchel; JOHN C. REED AND DIDIER Y., Stainie

    Metabolic Profiling of IDH Mutation and Malignant Progression in Infiltrating Glioma.

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    Infiltrating low grade gliomas (LGGs) are heterogeneous in their behavior and the strategies used for clinical management are highly variable. A key factor in clinical decision-making is that patients with mutations in the isocitrate dehydrogenase 1 and 2 (IDH1/2) oncogenes are more likely to have a favorable outcome and be sensitive to treatment. Because of their relatively long overall median survival, more aggressive treatments are typically reserved for patients that have undergone malignant progression (MP) to an anaplastic glioma or secondary glioblastoma (GBM). In the current study, ex vivo metabolic profiles of image-guided tissue samples obtained from patients with newly diagnosed and recurrent LGG were investigated using proton high-resolution magic angle spinning spectroscopy (1H HR-MAS). Distinct spectral profiles were observed for lesions with IDH-mutated genotypes, between astrocytoma and oligodendroglioma histologies, as well as for tumors that had undergone MP. Levels of 2-hydroxyglutarate (2HG) were correlated with increased mitotic activity, axonal disruption, vascular neoplasia, and with several brain metabolites including the choline species, glutamate, glutathione, and GABA. The information obtained in this study may be used to develop strategies for in vivo characterization of infiltrative glioma, in order to improve disease stratification and to assist in monitoring response to therapy

    Phenotypic integration of behavioural and physiological traits is related to variation in growth among stocks of Chinook salmon

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    The selection for a single organismal trait like growth in breeding programs of farmed aquaculture species can counterintuitively lead to lowered harvestable biomass. We outbred a domesticated aquaculture stock of Chinook salmon (Oncorhynchus tshawytscha (Walbaum in Artedi, 1792)) with seven wild stocks from British Columbia, Canada. We then examined how functionally related traits underlying energy management – diel variation in cortisol and foraging, social, and movement behaviours — predicted stock-level variation in growth during the freshwater life history stage, which is a performance metric under aquaculture selection. Outbreeding generated significant variation in diel cortisol secretion and behaviours across stocks, and these traits co-varied, suggesting tight integration despite hybridization. The coupling of nighttime cortisol exposure with the daytime behavioural phenotype was the strongest predictor of stock-level variation in body mass. Our results suggest that selection for an integrated phenotype rather than on a single mechanistic trait alone can generate the greatest effect on aquaculture fish growth under outbreeding practices. Furthermore, selecting for these traits at the stock level may increase efficiency of farming methods designed to consistently maximize fish performance on a large scale

    Phenotypic integration of behavioural and physiological traits is related to variation in growth among stocks of Chinook salmon

    Get PDF
    The selection for a single organismal trait like growth in breeding programs of farmed aquaculture species can counter-intuitively lead to lowered harvestable biomass. We outbred a domesticated aquaculture stock of Chinook salmon (Oncorhynchus tshawytscha) with 7 wild stocks from British Columbia, Canada. We then examined how functionally related traits underlying energy management - diel variation in cortisol; foraging, social, and movement behaviours - predicted stock-level variation in growth during the freshwater life history stage, a performance metric under aquaculture selection. Outbreeding generated significant variation in diel cortisol secretion and behaviours across stocks, and these traits covaried, suggesting tight integration despite hybridization. The coupling of nighttime cortisol exposure with daytime behavioural phenotype was the strongest predictor of stock-level variation in body mass. Our results suggest selecting for an integrated phenotype rather than on single mechanistic traits alone can generate the greatest effect on aquaculture fish growth under outbreeding practices. Furthermore, selecting for these traits at the stock level may increase efficiency of farming methods designed to consistently maximize fish performance on a large scale
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