Vascularization of the cloacal bursa in Gallus gallus domesticus (master gris cou plumé lineage)

Estudou-se a vascularização da bolsa cloacal em aves da linhagem Master Gris Cou Plumé, quanto a sua origem, número e distribuição dos vasos. Procedeu-se a dissecação dos vasos por meio de duas incisões paramedianas na base do pigóstilo, em 20 exemplares de seis semanas de idade após fixação em solução aquosa de formol a 10%. Anteriormente à fixação, a artéria isquiádica direita foi canulada para perfusão do sistema arterial com solução aquosa a 50% de Neoprene Látex “450”, corado com pigmento vermelho. A bolsa cloacal foi irrigada pelas artérias: bursocloacal direita, presente em 19 exemplares (95%) apresentando de um a cinco ramos arteriais; bursocloacal esquerda, presente em todos os casos (100%), apresentando de um a cinco ramos arteriais; cloacal direita, observada em 13 aves (65%), exibindo de um a quatro ramos arteriais; cloacal esquerda, presente em 13 aves (65%), emitindo de dois a três ramos arteriais; e ilíacas internas direita e esquerda, observadas uma única vez (5%), que enviaram dois ramos arteriais. Quanto à distribuição, pode-se afirmar que os quadrantes caudais da bolsa cloacal, de ambos antímeros, foram os que mais receberam ramos arteriais, sendo que o esquerdo recebeu ramos da A. bursocloacal, A. cloacal e A. ilíaca interna em 19 casos (95%), 13 (65%) e um (5%), respectivamente. Os quadrantes craniais direito e esquerdo foram irrigados por ramos da A. bursocloacal em cinco (25%) e quatro casos (20%), respectivamente. Foram observadas grandes variações no aporte sanguíneo da bolsa cloacal da linhagem estudada em relação às demais da espécie Gallus gallus domesticus, concluindo-se que estas diferenças podem estar associadas à maior ou menor funcionalidade do órgão, ou mesmo das características morfofuncionais da linhagem empregada. Estatisticamente não foram observadas diferenças em relação às artérias responsáveis pelo suprimento sanguíneo, quando considerado o antímero e o número de ramos arteriais enviados à bolsa cloacal. _________________________________________________________________________________ ABSTRACTThe vascularization of the cloacal bursa in fowls from Master Gris Cou Plumé lineage was studied in relation to origin, number and distribution of vessels. After cannulation of the right sciatic artery in 20 specimens of six-week-old, the arterial system was perfused with a 50% aqueous solution of Neoprene Latex "450" colored with red pigment. Subsequently the specimens were fixated in aqueous 10% formaldehyde. Vessels were dissected through two paramedian incisions at the base of the pygostyle. The cloacal bursa showed to be irrigated by the arteries: right bursocloacal, present in 19 specimens (95%) with one to five arterial branches; left bursocloacal, present in all cases (100%) and showing one to five arterial branches; right cloacal, observed in 13 birds (65%) with one to four arterial branches; left cloacal, also present in 13 birds, sending two to three arterial branches; and right and left internal iliac arteries, observed only in a single individual (5%), which sent two arterial branches. As for distribution, it can be stated that the caudal quadrants of both sides of cloacal bursa were the ones that most received arterial branches. The left one received branches from the bursocloacal, cloacal and internal iliac arteries in 19 (95%), 13 (65%) and one (5%) cases, respectively. The right and the left cranial quadrants were irrigated, respectively, by branches of the bursocloacal artery in five cases (25%) and in four cases (20%). Great variations in blood supply of cloacal bursa were observed in the lineage studied in relation to others lineages of the species Gallus gallus domesticus, concluding that these differences may be associated with greater or lesser functionality of this organ, or even the morphofunctional characteristics of the tested lineage. Statistically were not found significant differences in relation to the arteries responsible by blood supply when considered antimere and number of arterial branches sent to the cloacal bursa

Post-intervention Status in Patients With Refractory Myasthenia Gravis Treated With Eculizumab During REGAIN and Its Open-Label Extension

OBJECTIVE: To evaluate whether eculizumab helps patients with anti-acetylcholine receptor-positive (AChR+) refractory generalized myasthenia gravis (gMG) achieve the Myasthenia Gravis Foundation of America (MGFA) post-intervention status of minimal manifestations (MM), we assessed patients' status throughout REGAIN (Safety and Efficacy of Eculizumab in AChR+ Refractory Generalized Myasthenia Gravis) and its open-label extension. METHODS: Patients who completed the REGAIN randomized controlled trial and continued into the open-label extension were included in this tertiary endpoint analysis. Patients were assessed for the MGFA post-intervention status of improved, unchanged, worse, MM, and pharmacologic remission at defined time points during REGAIN and through week 130 of the open-label study. RESULTS: A total of 117 patients completed REGAIN and continued into the open-label study (eculizumab/eculizumab: 56; placebo/eculizumab: 61). At week 26 of REGAIN, more eculizumab-treated patients than placebo-treated patients achieved a status of improved (60.7% vs 41.7%) or MM (25.0% vs 13.3%; common OR: 2.3; 95% CI: 1.1-4.5). After 130 weeks of eculizumab treatment, 88.0% of patients achieved improved status and 57.3% of patients achieved MM status. The safety profile of eculizumab was consistent with its known profile and no new safety signals were detected. CONCLUSION: Eculizumab led to rapid and sustained achievement of MM in patients with AChR+ refractory gMG. These findings support the use of eculizumab in this previously difficult-to-treat patient population. CLINICALTRIALSGOV IDENTIFIER: REGAIN, NCT01997229; REGAIN open-label extension, NCT02301624. CLASSIFICATION OF EVIDENCE: This study provides Class II evidence that, after 26 weeks of eculizumab treatment, 25.0% of adults with AChR+ refractory gMG achieved MM, compared with 13.3% who received placebo

Minimal Symptom Expression' in Patients With Acetylcholine Receptor Antibody-Positive Refractory Generalized Myasthenia Gravis Treated With Eculizumab

The efficacy and tolerability of eculizumab were assessed in REGAIN, a 26-week, phase 3, randomized, double-blind, placebo-controlled study in anti-acetylcholine receptor antibody-positive (AChR+) refractory generalized myasthenia gravis (gMG), and its open-label extension

ATLANTIC-PRIMATES: a dataset of communities and occurrences of primates in the Atlantic Forests of South America

Primates play an important role in ecosystem functioning and offer critical insights into human evolution, biology, behavior, and emerging infectious diseases. There are 26 primate species in the Atlantic Forests of South America, 19 of them endemic. We compiled a dataset of 5,472 georeferenced locations of 26 native and 1 introduced primate species, as hybrids in the genera Callithrix and Alouatta. The dataset includes 700 primate communities, 8,121 single species occurrences and 714 estimates of primate population sizes, covering most natural forest types of the tropical and subtropical Atlantic Forest of Brazil, Paraguay and Argentina and some other biomes. On average, primate communities of the Atlantic Forest harbor 2 ± 1 species (range = 1–6). However, about 40% of primate communities contain only one species. Alouatta guariba (N = 2,188 records) and Sapajus nigritus (N = 1,127) were the species with the most records. Callicebus barbarabrownae (N = 35), Leontopithecus caissara (N = 38), and Sapajus libidinosus (N = 41) were the species with the least records. Recorded primate densities varied from 0.004 individuals/km 2 (Alouatta guariba at Fragmento do Bugre, Paraná, Brazil) to 400 individuals/km 2 (Alouatta caraya in Santiago, Rio Grande do Sul, Brazil). Our dataset reflects disparity between the numerous primate census conducted in the Atlantic Forest, in contrast to the scarcity of estimates of population sizes and densities. With these data, researchers can develop different macroecological and regional level studies, focusing on communities, populations, species co-occurrence and distribution patterns. Moreover, the data can also be used to assess the consequences of fragmentation, defaunation, and disease outbreaks on different ecological processes, such as trophic cascades, species invasion or extinction, and community dynamics. There are no copyright restrictions. Please cite this Data Paper when the data are used in publications. We also request that researchers and teachers inform us of how they are using the data. © 2018 by the The Authors. Ecology © 2018 The Ecological Society of Americ

Educomunicação e suas áreas de intervenção: Novos paradigmas para o diálogo intercultural

oai:omp.abpeducom.org.br:publicationFormat/1O material aqui divulgado representa, em essência, a contribuição do VII Encontro Brasileiro de Educomunicação ao V Global MIL Week, da UNESCO, ocorrido na ECA/USP, entre 3 e 5 de novembro de 2016. Estamos diante de um conjunto de 104 papers executivos, com uma média de entre 7 e 10 páginas, cada um. Com este rico e abundante material, chegamos ao sétimo e-book publicado pela ABPEducom, em seus seis primeiros anos de existência. A especificidade desta obra é a de trazer as “Áreas de Intervenção” do campo da Educomunicação, colocando-as a serviço de uma meta essencial ao agir educomunicativo: o diálogo intercultural, trabalhado na linha do tema geral do evento internacional: Media and Information Literacy: New Paradigms for Intercultural Dialogue

Fuzzy Controller Applied to a Remote Energy Harvesting Emulation Platform

In the last decades, a lot of effort has been made in order to improve the use of environmentally friendly and renewable energy sources. In a context of small energy usage, energy harvesting takes place and thermal energy sources are one of its main energy sources because there are several unused heat sources available in the environment that may be used as renewable energy sources. To rapidly evaluate the energy potential of such thermal sources is a hard task, therefore, a way to perform this is welcome. In this work, a thermal pattern emulation system to evaluate potential thermal source in a easy way is proposed. The main characteristics of the proposed system is that it is online and remote, that is, while the thermal-source-under-test is being measured, the system is emulating it and evaluating the generated energy remotely. The main contribution of this work was to replace the conventional Proportional Integral Derivative (PID) controller to a Fuzzy-Proportional Integral (PI) controller. In order to compare both controllers, three tests were carried out, namely: (a) step response, (b) perturbation test, (c) thermal emulation of the thermal pattern obtained from a potential thermal source: tree trucks. Experimental results show that the Fuzzy-PI controller was faster than the PID, achieving a setting time 41.26% faster, and also was more efficient with a maximum error 53% smaller than the PID

Postural hypotension in geriatric outpatient clinic of the Hospital do Servidor Público Estadual de São Paulo

OBJECTIVE: Assess the frequency of orthostatic hypotension and its symptoms in outpatients and identify possible risk factors for the patient's profile. METHOD: A hundred elderly aged 65 years old or over it of both sexes that sought outpatient care at "Hospital do Servidor P&uacute;blico Estadual", had their the blood pressure measured in the supine position after a resting of 3 minutes in this position and in a standing position after 1 - 3 minutes, when the patient was asked about the symptoms. The risk factors for orthostatic hypotension were asked previously. RESULTS: Frequency of orthostatic hypotension was 38% and of these only 11% had symptoms. The association of changes in systolic and diastolic blood pressure was more frequent, 24%, compared to isolated changes. One or more risk factors were found in all patients of the sample, and the use of medications and hypertension were the most common. CONCLUSION: There is a high frequency of orthostatic hypotension in ambulatory elderly, especially chronic users of drugs and hypertense elders.</p

Escalas de Borg e OMINI na prescrição de exercício em cicloergômetro

As escalas de percepção de esforço de Borg e OMNI são amplamente validadas para identificação da intensidade do exercício. O estudo teve como objetivo testar a correspondência entre as categorias das Escalas de Borg (6-20) e OMNI-Ciclismo na prescrição de exercícios em cicloergômetro e propor uma nova tabela de conversão entre as escalas. Vinte seis homens (17-41 anos de idade), praticantes de Ciclismo Indoor, pedalaram por 3 minutos, em 6 cargas auto selecionadas correspondentes às categorias de percepção de esforço 9, 11, 13, 15, 17, 19 para Borg, em uma sessão e 2, 4, 5, 7, 8 e 10 para OMNI, em outra sessão. Ao final de cada estágio, a frequência cardíaca (FC) e a potência (W) foram registradas. Calculou-se a correlação de Pearson entre as escalas. A correspondência entre as categorias das escalas foi testada pela ANOVA para medidas repetidas, seguida do teste de Tuckey (p < 0,05). Foi encontrada alta correlação entre as duas escalas (r = 0,87; P < 0,05) e diferença significativa na FC para as três primeiras categorias. Quanto a W, encontrou-se diferença significativa apenas nas duas primeiras categorias. A conversão testada mostrou correlação significante. Entretanto, há diferenças significantes na FC para as três primeiras categorias e na W para as duas primeiras. A seguinte correspondência foi proposta: Borg 11, 13, 15, 17 e 19; para OMNI 2, 4, 7, 8 e 10

<b>OMNI and Borg scales for the prescription of cycle ergometer exercise.</b> DOI: 10.5007/1980-0037.2011v13n2p117

The Borg and OMNI scales of perceived exertion have been widely validated for the identification of exercise intensity. The objective of this study was to test the agreement between the categories of the Borg (6-20) and OMNI-Cycle scales for the prescription of cycle ergometer exercise and to propose a new conversion table. Twenty-six male indoor cyclists (17-41 years) pedalled for 3 min at six self-selected increasing loads. These loads corresponded to categories 9, 11, 13, 15, 17, and 19 of the Borg scale in one session, and to categories 2, 4, 5, 7, 8, and 10 of the OMNI scale in the other session. At the end of each stage, heart rate (HR) and power (W) were recorded. Pearson’s correlation coefficient between scales was calculated. Agreement between the categories of the scales was tested by ANOVA for repeated measures, followed by the Tukey test (p < 0.05). The correlation between the two scales was high (r = 0.87, p < 0.05). Significant difference between the two scales was observed for HR in the first three categories. W differed significantly only in the first two categories. The conversion tested showed a significant correlation. However, there were significant differences in HR in the first three categories and in W in the first two. The following agreement is proposed: Borg 11, 13, 15, 17, and 19 corresponding to OMNI 2, 4, 7, 8, and 10