1,628 research outputs found
Observation of zero-point quantum fluctuations of a single-molecule magnet through the relaxation of its nuclear spin bath
A single-molecule magnet placed in a magnetic field perpendicular to its
anisotropy axis can be truncated to an effective two-level system, with easily
tunable energy splitting. The quantum coherence of the molecular spin is
largely determined by the dynamics of the surrounding nuclear spin bath. Here
we report the measurement of the nuclear spin--lattice relaxation in a single
crystal of the single-molecule magnet Mn-ac, at mK in
perpendicular fields up to 9 T. Although the molecular spin is in
its ground state, we observe an increase of the nuclear relaxation rates by
several orders of magnitude up to the highest . This unique finding
is a consequence of the zero-point quantum fluctuations of the Mn-ac
spin, which allow it to efficiently transfer energy from the excited nuclear
spin bath to the lattice. Our experiment highlights the importance of quantum
fluctuations in the interaction between an `effective two-level system' and its
surrounding spin bath.Comment: 5 pages, 4 figure
Complex-linear invariants of biochemical networks
The nonlinearities found in molecular networks usually prevent mathematical
analysis of network behaviour, which has largely been studied by numerical
simulation. This can lead to difficult problems of parameter determination.
However, molecular networks give rise, through mass-action kinetics, to
polynomial dynamical systems, whose steady states are zeros of a set of
polynomial equations. These equations may be analysed by algebraic methods, in
which parameters are treated as symbolic expressions whose numerical values do
not have to be known in advance. For instance, an "invariant" of a network is a
polynomial expression on selected state variables that vanishes in any steady
state. Invariants have been found that encode key network properties and that
discriminate between different network structures. Although invariants may be
calculated by computational algebraic methods, such as Gr\"obner bases, these
become computationally infeasible for biologically realistic networks. Here, we
exploit Chemical Reaction Network Theory (CRNT) to develop an efficient
procedure for calculating invariants that are linear combinations of
"complexes", or the monomials coming from mass action. We show how this
procedure can be used in proving earlier results of Horn and Jackson and of
Shinar and Feinberg for networks of deficiency at most one. We then apply our
method to enzyme bifunctionality, including the bacterial EnvZ/OmpR osmolarity
regulator and the mammalian
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase glycolytic regulator,
whose networks have deficiencies up to four. We show that bifunctionality leads
to different forms of concentration control that are robust to changes in
initial conditions or total amounts. Finally, we outline a systematic procedure
for using complex-linear invariants to analyse molecular networks of any
deficiency.Comment: 36 pages, 6 figure
Nuevas tecnologías en la corrección de las deformidades de la columna vertebral. Sistema Transpine
Los sistemas de corrección de última generación para el tratamiento de las deformidades del ra
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quis han suscitado gran controversia. Realizamos un recuerdo histórico del tratamiento quirúrgico de las afeccio
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nes de la columna y describimos un sistema de última generación que permite montajes híbridos (uñas, tornillos
pediculares y cables de tracción). Se han intervenido un total de 200 escoliosis idiopáticas neuropáticas y congé
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nitas desde 2004 hasta 2010 con el sistema Transpine
®
mediante montaje híbrido. Todos los pacientes han sido
intervenidos por el mismo cirujano. Se analizó el porcentaje de corrección posoperatoria obtenida. Se observa
un cambio 70% y 30% del eje coronal y sagital respectivamente (P<0.001). Las pérdidas angular fueron <10º. El
sistema Transpine
®
permite la posibilidad de realizar montajes híbridos sin complicaciones para el tratamiento de
las deformidades. Los resultados obtenidos son comparables con los publicados en la bibliografía.Correction systems of the latest generation for the treatment of spinal deformities have aroused
great controversy. We conducted a historical review of the surgical treatment and we describe a new system that
allows the use of hybrid assemblies (claws, pedicle screws and pull cable wires). A total of 200 patients from
2004 to 2010 with idiopathic scoliosis, congenital neuropathic were operated with the Transpine
®
system using
hybrid assembly. The correction percentage of postoperative obtained was analyzed. Change 70% and 30% res
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pectively of the coronal and sagittal axis was observed (P <0.001). The angular losses were <10º. The Transpine
®
system let surgeons to perform uncomplicated hybrid safely assemblies for treatment of deformities. The results
are comparable with those published in the literature
Color pattern recognition with circular component whitening
Polychromatic object recognition based on circular whitening preprocessing of red-green-blue components and multichannel matched filtering is described. Computer simulations and experimental results are provided to facilitate recognizing a color target among objects of similar shape but with different color contents. Experimental results are obtained with an optical correlator with two spatial light modulators, one to introduce the scene and the second one to introduce the filter
Observation of zero-point quantum fluctuations of a single-molecule magnet through the relaxation of its nuclear spin bath
Under the terms of the Creative Commons Attribution License 3.0 (CC-BY).A single-molecule magnet placed in a magnetic field perpendicular to its anisotropy axis can be truncated to an effective two-level system, with easily tunable energy splitting. The quantum coherence of the molecular spin is largely determined by the dynamics of the surrounding nuclear spin bath. Here we report the measurement of the nuclear spin-lattice relaxation rate 1/T1n in a single crystal of the single-molecule magnet Mn12-ac, at T≈30 mK in perpendicular fields B⊥ up to 9 T. The relaxation channel at B≈0 is dominated by incoherent quantum tunneling of the Mn12-ac spin S, aided by the nuclear bath itself. However for B⊥>5 T we observe an increase of 1/T1n by several orders of magnitude up to the highest field, despite the fact that the molecular spin is in its quantum mechanical ground state. This striking observation is a consequence of the zero-point quantum fluctuations of S, which allow it to mediate the transfer of energy from the excited nuclear spin bath to the crystal lattice at much higher rates. Our experiment highlights the importance of quantum fluctuations in the interaction between an >effective two-level system> and its surrounding spin bath. © 2014 American Physical Society.This work has been part of the research program of the “Stichting FOM.”Peer Reviewe
Photon creation in a spherical oscillating cavity
We study the photon creation inside a perfectly conducting, spherical
oscillating cavity. The electromagnetic field inside the cavity is described by
means of two scalar fields which satisfy Dirichlet and (generalized) Neumann
boundary conditions. As a preliminary step, we analyze the dynamical Casimir
effect for both scalar fields. We then consider the full electromagnetic case.
The conservation of angular momentum of the electromagnetic field is also
discussed, showing that photons inside the cavity are created in singlet
states.Comment: 14 pages, no figure
Reverse engineering the euglenoid movement
Euglenids exhibit an unconventional motility strategy amongst unicellular eukaryotes, consisting of large-amplitude highly concerted deformations of the entire body (euglenoid movement or metaboly). A plastic cell envelope called pellicle mediates these deformations. Unlike ciliary or flagellar motility, the biophysics of this mode is not well understood, including its efficiency and molecular machinery. We quantitatively examine video recordings of four euglenids executing such motions with statistical learning methods. This analysis reveals strokes of high uniformity in shape and pace. We then interpret the observations in the light of a theory for the pellicle kinematics, providing a precise understanding of the link between local actuation by pellicle shear and shape control. We systematically understand common observations, such as the helical conformations of the pellicle, and identify previously unnoticed features of metaboly. While two of our euglenids execute their stroke at constant body volume, the other two exhibit deviations of about 20% from their average volume, challenging current models of low Reynolds number locomotion. We find that the active pellicle shear deformations causing shape changes can reach 340%, and estimate the velocity of the molecular motors. Moreover, we find that metaboly accomplishes locomotion at hydrodynamic efficiencies comparable to those of ciliates and flagellates. Our results suggest new quantitative experiments, provide insight into the evolutionary history of euglenids, and suggest that the pellicle may serve as a model for engineered active surfaces with applications in microfluidics
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