Solmec: an efficient c++ library to solve linear and nonlinear elasticity problems

A C++ library based on local maximum-entropy approximation schemes to solve linear and nonlinear elasticity problem is presented. The available tools are briefly described, and several implementation details are also mentioned. Selected numerical examples are shown in order to illustrate the capabilities of the library. The current and future developments are indicated.Peer Reviewe

Numerical integration by using local-node gauss-hermite cubature

A local–node numerical integration scheme for meshless methods is presented in this work. The distinguishing characteristic of the introduced scheme is that not support mesh or grid to perform numerical integration is needed, besides the fact that gauss cubature points for each node are generated in a properly fashion and that the extension of the methodology to high dimensions is straightforward. The numerical integration is computed with the Gauss–Hermite cubature formulas, and the partition of unity is employed to introduce the Gaussian weight in a natural way. Selected numerical tests in two-dimensions are used to illustrate the validity of the proposed methodology. Although the obtained results are encouraging, the behavior of the integration error is not still well understood when the dimensionless parameter which control the width of the Gaussian kernel varies

LABORATORIOS DE INNOVACIÓN PÚBLICA EN AMÉRICA LATINA: CAMBIO Y ESTABILIDAD EN GOBIERNOS LOCALES

Con la finalidad de aportar elementos más puntuales sobre el fenómeno de los Laboratorios de Innovación Pública, LIP en términos organizacionales y de política pública, en la presente tesis se hace una revisión exhaustiva de tres casos de LIP de América Latina: (011).lab (Brasil), LABcapital (Colombia) y Lab León (México). En este sentido, cada uno de los casos identificados tienen un abordaje particular, en función de sus características específicas, además de la recolección bibliográfica, documental y electrónica, así como la solicitud de información vía electrónica de forma directa con los coordinadores de los laboratorios. La estrategia adoptada en la presente investigación es el análisis de datos cualitativos derivados de: i) entrevistas a informantes calificados seleccionados y ii) fuentes documentales secundarias relevantes para una serie de casos seleccionados a partir del resultado de la exploración de LIP. Los resultados sugieren que los LIP se desarrollan y estabilizan cuando se definen como instituciones gubernamentales inmersas en la estructura organizacional de los gobiernos en los que actúan, cuando plantean dos entornos integrales de acción: el interno y el externo. Al visualizar y actuar de forma integral generando capacidades estatales y ciudadanas de innovación, especifican de forma clara la finalidad de generar un cambio profundo en la cultura y dinámica de innovación para el mejoramiento de los servicios públicos, actuando en ambos frentes y propiciando la colaboración de ambos entornos

Freedom of Speech in Spain Based on the Case Law of the European Court of Human Rights

Resumen: El derecho a la libertad de expresión se caracteriza por ser uno de los derechos más valiosos dentro de las sociedades democráticas avanzadas. Tal es así que el Convenio Europeo de Derechos Humanos dota a este derecho fundamental de un elevado ámbito de protección. A través de su jurisprudencia, el Tribunal Europeo de Derechos Humanos ha reforzado una serie de garantías para no desnaturalizarlo, siendo muy aprensivo a la hora de restringir la libertad de expresión de los ciudadanos europeos, como vemos a lo largo del presente trabajo. No dudamos tampoco que debido a las redes de comunicación contemporáneas nos encontramos con nuevos problemas que debemos afrontar conjuntamente de manera universal, para evitar abusos en el derecho a la libertad de expresión de las personas en internet. La protección del Tribunal Europeo a la libertad de expresión ha dado lugar a importantes sentencias contra España en los casos Otegi y Stern Taulats y Roura Capellera. Ambas centran nuestro estudio con el fin de averiguar si los tribunales españoles están aplicando adecuadamente la jurisprudencia que se deriva de las mismas en los asuntos sobre libertad de expresión de mayor impacto social y mediático en la actualidad.Abstract: The right to freedom of speech is characterized for being one of the most valuable rights in advanced democratic societies. So that, the European Convenion on Human Rights gives this fundamental right a high level protection. Throughout its case law, the European Court of Human Rights has intensified guarantees as not to denature it, being very apprehensive about restricting the freedom of expression of European citizens. In 3 addition, due to contemporary communication networks we must deal with new problems that we should face together in a universal way, in order to avoid abuses of the right to freedom of speech for people on internet. The European Court's protection of freedom of speech has led to important judgments against Spain in the Otegi and Stern Taulats and Roura Capellera cases. Besides both focus our study so as to find out if the spanish courts are adequately applying the jurisprudence derived from them in matters of freedom of speech with the greatest social and media impact nowadays.Grado en Derech

Advances in aquatic and subterranean beetles research: a tribute to Ignacio Ribera

It has been a bit longer than two years since our friend and colleague Ignacio (Nacho) Ribera passed away. The memory of him remains among those of us who were lucky enough to meet Nacho. This monograph is dedicated to him, bringing a set of scientific contributions from his colleagues whose topics are part of the main research lines (and passions) of his scientific work: taxonomy, systematics, biogeography and evolution of aquatic and subterranean beetles. In the last two years, several contributions have highlighted Nacho’ scientific and personal profile, including the complete list of his publications, and both the taxa described by and dedicated to him (BELLÉS, 2020; CEHRE, 2020; DELOCADO et al., 2020; FAILLE et al., 2020, 2021; JÄCH, 2020; MELIC, 2020; MILLÁN et al., 2020a, b; VALLADARES & MILLÁN, 2020). Nacho was a passionate biologist, interested in everything concerning beetles, especially their diversity, distributions, adaptations and evolution of aquatic and cave beetles. He published a total of 285 papers, in which he described 107 species new to science, highlighting the discovery of the Aspyditidae family. Besides, 7 species and subspecies, and one new genus have been dedicated to him in this monograph, extending to a total of 15 species and two genera. Concerning the aquatic beetles, we would like to emphasise his crucial contributions, such as the first complete checklist of aquatic and semi-aquatic beetles of the Iberian Peninsula. He was a pioneer in studying the adaptive morphology of the family Dytiscidae, and more importantly, he deepens in the phylogeny of the aquatic beetles, shedding light on the systematics and evolution of the families Dytiscidae and Hydraenidae. He postulated the “Habitat Constraint” hypothesis which, from an evolutionary point of view, highlights the importance of habitat stability as a determinant of species range sizes (via differences in their dispersal capabilities). He also dealt in-depth with evolutionary studies related to the habitat transition between lotic and lentic water bodies, but also the transition from freshwater to saline water, or vice versa. Certainly, Nacho, due to his work and publications on aquatic beetles, became one of the most prestigious specialists worldwide. Regarding the subterranean environment, Nacho revealed that Dalyat Mateu is a vicariant genus of carabid whose origin must be in the separation of the Iberian plate from the rest of Pangea in the Jurassic-Cretaceous boundary. He also addressed the position of Ildobates neboti Español, confirming it within the Zuphiini tribe. At the same time, he began to study the phylogeny of the hypogeal Trechini of the Pyrenees, and afterwards he addressed the diversification of Troglocharinus Reitter, opening the way to a new perspective on the evolution and dispersion of the subterranean fauna. He published the first morphological phylogeny through cladistic analysis of the Leptodirini tribe (Leiodidae), and the first molecular phylogenies for the two main groups that have colonised the subterranean environment, the tribes Leptodirini and Trechini. His contribution to the knowledge of underground and stygobic environments between 2005 and 2021, postulated him as one of the most important specialists worldwide also in this field. The complete list of scientific works signed by Nacho, the taxa described by him and those dedicated to his person can be found on the web: https://www.um.es/ecoaqua/index.php/external-collaborators. We do not want to extend further. We hope these pages serve as a tribute to his person, but also a tribute to a life and scientific style that would serve as an example for future generations of insect lovers. Our gratitude to the authors and reviewers of the articles that make up this monograph, as well as to the Asociación española de Entomología, which has greatly facilitated its preparation, edition and publication

Estudios sobre la población X-frágil en Aragón

La enfermedad conocida como síndrome X frágil es una de las causas más habituales de discapacidad intelectual y autismo en las sociedades modernas. Este síndrome afecta a la regulación de la transcripción del mRNA de la proteína FMRP en las neuronas, un elemento fundamental en el control de la expresión de otros genes. Actualmente su origen se desconoce y no hay tratamiento, por lo que el diagnóstico temprano juega un papel crucial para mejor calidad de vida de los individuos afectos. En este estudio se han analizado los casos del Hospital Universitario Miguel Servet de Zaragoza con alteraciones genéticas relacionadas con dicho síndrome. Se ha llevado a cabo una comparativa de la metodología empleada para su diagnóstico entre los años 2011 y 2015, así como un estudio en profundidad de un caso particular en el que no hay una correlación entre el genotipo característico del síndrome de X frágil y el fenotipo que cabría esperar. Además se ha realizado una investigación para intentar demostrar la relación de esta alteración genética con el polimorfismo C667T de la metil tetrahidrofolato reductasa (MTHR) como apuntan algunos estudios recientes pero sin llegar a resultados concluyentes

Antioxidant, antidiabetic, and anti-obesity properties of apple pulp extracts (Malus Domestica Bork): a comparative study of 15 local and commercial cultivars from Spain

Apples (Malus domestica Borkh.) have a great agricultural and economic impact worldwide; they also present an interesting nutritional value, and their consumption has been associated with beneficial health effects. In this study, 15 apple varieties (three commercial, 12 autochthonous genotypes) were collected from mountainous areas in Spain and were evaluated for their phenolic content, antioxidant, anti-obesity and antidiabetic activities. Quercetin was tested as the reference substance in bioassays due to its role as one of the most common flavonoids in apples and other vegetables. Total Phenolic Content (TPC) of apple pulp extracts was quantified using the Folin-Ciocalteu method. The antioxidant activity was determined by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging and xanthine/xanthine oxidase (X/XO) scavenging assays. Antidiabetic and anti-obesity potential were evaluated by inhibition of alpha-glucosidase (α-GLU), advance glycation end products (AGEs) formation and pancreatic lipase. The results showed in general higher phenol content in autochthonous varieties than in commercial apple pulp extracts. Phenolic-rich extracts showed better antioxidant profiles and significantly inhibited AGEs production and the α-glucosidase enzyme in a dose-dependent manner. None of them showed pancreatic lipase inhibitory effects but in general, the genotype known as “Amarilla de Octubre” was the best in terms of TPC and bioactive properties

Manejo clínico de las lesiones endoperiodontales. A próposito de varios casos

El endodonto y el periodonto son dos entidades íntimamente relacionadas que comparten estrechas interacciones embriológicas, anatómicas, fisiopatológicas y funcionales. Esta proximidad proporciona a la pulpa y a los tejidos periodontales un intercambio continuo a través de numerosas y variadas vías de comunicación endo-periodontales.Una patología en uno de los dos tejidos repercute en consecuencia en el otro, aunque el origen primario de la infección (endodóntica y/o periodontal) es difícil de determinar. En este sentido, un enfoque clínico riguroso en el cual se adopta un razonamiento pertinente basado en la historia de laenfermedad, con los exámenes clínicos y radiográficos completos resulta necesario para establecer el diagnóstico de una lesión endo-periodontal combinada, del que se derive una terapia endodóntica y periodontal.El presente trabajo de fin de grado pretende describir la relación entre el tejido pulpar y periodontal, aclarar la etiología de las lesiones endoperiodontales y arrojar luz, a través de una serie de casos clínicos, sobre el enfoque diagnóstico y terapéutico de este tipo de lesiones, basándonos en la literatura científica más adecuada y actualizada.<br /

High efficient luminescence in type-II GaAsSb-capped InAs quantum dots upon annealing

The photoluminescence efficiency of GaAsSb-capped InAs/GaAs type II quantum dots (QDs) can be greatly enhanced by rapid thermal annealing while preserving long radiative lifetimes which are ∼20 times larger than in standard GaAs-capped InAs/GaAs QDs. Despite the reduced electron-hole wavefunction overlap, the type-II samples are more efficient than the type-I counterparts in terms of luminescence, showing a great potential for device applications. Strain-driven In-Ga intermixing during annealing is found to modify the QD shape and composition, while As-Sb exchange is inhibited, allowing to keep the type-II structure. Sb is only redistributed within the capping layer giving rise to a more homogeneous composition