11,878 research outputs found

    Priming in interpersonal contexts: Implications for affect and behavior

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    Priming stereotypes can lead to a variety of behavioral outcomes, including assimilation, contrast, and response behaviors. However, the conditions that give rise to each of these outcomes are unspecified. Furthermore, theoretical accounts posit that prime-to-behavior effects are either direct (i.e., unmediated) or mediated by cognitive processes, whereas the role of affective processes has been largely unexplored. The present research directly investigated both of these issues. Three experiments demonstrated that priming a threatening social group ("hoodies") influences both affect and behavior in an interpersonal context. Hoodie priming produced both behavioral avoidance and several affective changes (including social apprehension, threat sensitivity, and self-reported anxiety and hostility). Importantly, avoidance following hoodie priming was mediated by anxiety and occurred only under conditions of other-(but not self-) focus. These results highlight multiple routes through which primes influence affect and behavior, and suggest that attention to self or others determine the nature of priming effects

    Type II superlattices for infrared detectors and devices

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    Superlattices consisting of combinations of III-V semiconductors with type II band alignments are of interest for infrared applications because their energy gaps can be made smaller than those of any 'natural' III-V compounds. Specifically, it has been demonstrated that both InSb/InAsxSb1-x superlattices and Ga1-xInxSb/InAs superlattices can possess energy gaps in the 8-14 mu m range. The efforts have focused on the Ga1-xInxSb/InAs system because of its extreme broken gap band alignment, which results in narrow energy gaps for very short superlattice periods. The authors report the use of in situ chemical doping of Ga1-xInxSb/InAs superlattices to fabricate p-n photodiodes. These diodes display a clear photovoltaic response with a threshold near 12 mu m. They have also attained outstanding structural quality in Ga1-xInxSb/InAs superlattices grown on radiatively heated GaSb substrates. Cross-sectional transmission electron microscope images of these superlattices display no dislocations, while high resolution X-ray diffraction scans reveal sharp high-order superlattice satellites and strong Pendellosung fringes

    Supporting the 'Sharing Institution' - Practical Steps Towards a More Open Teaching and Learning Culture

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    4th International Conference on Open RepositoriesThis presentation was part of the session : Conference PresentationsDate: 2009-05-19 03:00 PM – 04:30 PMInstitutional repositories for research output have developed progressively over the last few years. Although a primary motivation is Open Access both institutional and academic needs must also be met in order to foster this spirit effectively. There is now a greater emphasis on creating a more open culture for teaching and learning and institutions are again beginning to play their part more readily. On a larger scale, there are pioneering global examples of courses being preserved and complex learning materials being deposited in national and international databases. But what does fostering a more open culture in the practice of teaching mean for the institution itself and its academics? The virtual learning environment has given greater opportunities for effective administration of courses but in other ways it has had the opposite effect on sharing and re-use. There is potential for institutional solutions which are complementary to the global landscape. In this paper we report on the practical experiences and issues met, in setting up a institutional resource, EdShare, as a vehicle for sharing educational materials more easily in a multi-disciplinary institution. With constructive feedback from faculty, within the EdSpace project, EdShare has migrated into a more visual, web 2.0 style, resource with a flexible deposit process promoting 'micro-sharing'. It now offers a range of sharing options to support the teaching workflow in an encouraging atmosphere. Other features will support the growing emphasis on multidisciplinary teaching and collaboration - both internally and externally.JIS

    Plasma deposition of constrained layer damping coatings

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    Plasma techniques are used to generate constrained layer damping (CLD) coatings on metallic substrates. The process involves the deposition of relatively thick, hard ceramic layers on to soft polymeric damping materials while maintaining the integrity of both layers. Reactive plasma sputter-deposition from an aluminium alloy target is used to deposit alumina layers, with Young's modulus in the range 77-220GPa and thickness up to 335 μ, on top of a silicone film. This methodology is also used to deposit a 40 μ alumina layer on a conventional viscoelastic damping film to produce an integral damping coating. Plasma CLD systems are shown to give at least 50 per cent more damping than equivalent metal-foil-based treatments. Numerical methods for rapid prediction of the performance of such coatings are discussed and validated by comparison with experimental results

    Efficacy of cognitive behaviour therapy versus anxiety management for body dysmorphic disorder: a randomised controlled trial

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    Background: The evidence base for the effectiveness of cognitive behaviour therapy (CBT) for treating Body Dysmorphic Disorder (BDD) is weak. Aims: To determine if CBT is more effective than anxiety management (AM) in an out-patient setting. Method: A single blind, stratified parallel-group randomized controlled trial. The primary endpoint was at 12 weeks, and the Yale Brown Obsessive Compulsive Scale for BDD (BDD-YBOCS) was the primary outcome measure. Secondary measures for BDD included the Brown Assessment of Beliefs (BABS), the Appearance Anxiety Inventory (AAI) and the Body Image Quality of Life Inventory (BIQLI). The outcome measures were collected at baseline and week 12. The CBT group, unlike the AM group, had 4 further weekly sessions that were analysed for their added value. Both groups then completed measures at their 1-month follow-up. Forty-six participants, with DSM-IV diagnosis of BDD including those with a delusional BDD were randomly allocated to either CBT or AM. Results: At 12 weeks, CBT was found to be significantly superior to AM on the BDD-YBOCS ( = -7.19, S.E. () = 2.61, p < .01, C.I. = -12.31, -2.07, d 0.99) as well as the secondary outcome measures of the BABS, AAI and BIQL. Further benefits occurred by Week 16 within the CBT group. There were no differences in outcome for those with delusional BDD or depression. Conclusions: CBT is an effective intervention for people with BDD even with delusional beliefs or depression and is more effective than anxiety management over 12 weeks

    A phase Ib/II study of cabozantinib (XL184) with or without erlotinib in patients with non-small cell lung cancer.

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    PurposeCabozantinib is a multi-kinase inhibitor that targets MET, AXL, and VEGFR2, and may synergize with EGFR inhibition in NSCLC. Cabozantinib was assessed alone or in combination with erlotinib in patients with progressive NSCLC and EGFR mutations who had previously received erlotinib.MethodsThis was a phase Ib/II study (NCT00596648). The primary objectives of phase I were to assess the safety, pharmacokinetics, and pharmacodynamics and to determine maximum tolerated dose (MTD) of cabozantinib plus erlotinib in patients who failed prior erlotinib treatment. In phase II, patients with prior response or stable disease with erlotinib who progressed were randomized to single-agent cabozantinib 100 mg qd vs cabozantinib 100 mg qd and erlotinib 50 mg qd (phase I MTD), with a primary objective of estimating objective response rate (ORR).ResultsSixty-four patients were treated in phase I. Doses of 100 mg cabozantinib plus 50 mg erlotinib, or 40 mg cabozantinib plus 150 mg erlotinib were determined to be MTDs. Diarrhea was the most frequent dose-limiting toxicity and the most frequent AE (87.5% of patients). The ORR for phase I was 8.2% (90% CI 3.3-16.5). In phase II, one patient in the cabozantinib arm (N = 15) experienced a partial response, for an ORR of 6.7% (90% CI 0.3-27.9), with no responses for cabozantinib plus erlotinib (N = 13). There was no evidence that co-administration of cabozantinib markedly altered erlotinib pharmacokinetics or vice versa.ConclusionsDespite responses with cabozantinib/erlotinib in phase I, there were no responses in the combination arm of phase II in patients with acquired resistance to erlotinib. Cabozantinib did not appear to re-sensitize these patients to erlotinib

    Amplitude equations and pattern selection in Faraday waves

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    We present a systematic nonlinear theory of pattern selection for parametric surface waves (Faraday waves), not restricted to fluids of low viscosity. A standing wave amplitude equation is derived from the Navier-Stokes equations that is of gradient form. The associated Lyapunov function is calculated for different regular patterns to determine the selected pattern near threshold. For fluids of large viscosity, the selected wave pattern consists of parallel stripes. At lower viscosity, patterns of square symmetry are obtained in the capillary regime (large frequencies). At lower frequencies (the mixed gravity-capillary regime), a sequence of six-fold (hexagonal), eight-fold, ... patterns are predicted. The regions of stability of the various patterns are in quantitative agreement with recent experiments conducted in large aspect ratio systems.Comment: 12 pages, 1 figure, Revte

    The effect of melt composition and oxygen fugacity on manganese partitioning between apatite and silicate melt

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    Oxygen fugacity and melt composition are both known to have a strong influence on the partitioning of trace elements between coexisting minerals and melt. Previous work has suggested that Mn partitioning between apatite and silicate melt may be strongly affected by oxygen fugacity and could, therefore, act as an oxybarometer. Here, we present a new study on the partitioning of Mn between apatite and melt at high temperature (1400–1250 °C) and 1 GPa pressure, for various melt compositions and oxygen fugacities (NNO +4.7 to NNO -10). We find that there is no demonstrable variation in the partition coefficient for Mn between apatite and silicate melt (D MnAp-m ) across the range of fO 2 conditions studied here. Instead, we find that D MnAp-m varies significantly with melt composition and that in particular, the proportion of non-bridging oxygens strongly influences partitioning of Mn between apatite and melt. We propose that variations in the Mn content of natural apatite, previously thought to reflect variations in fO 2 , are instead related to the degree of melt polymerisation. These findings are consistent with the results of Mn K-edge XANES spectroscopy, which demonstrate that Mn in coexisting apatite and silicate glass is present predominantly as Mn 2+ regardless of fO 2. Furthermore, XANES spectra from a series of silicate glasses synthesised at various oxygen fugacities demonstrate that Mn 2+ is the predominant species, and that the average Mn oxidation state does not vary over a wide range of fO 2 -T conditions

    Surgical Infection Prophylaxis for Left Ventricular Assist Device Implantation

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/86804/1/j.1540-8191.2011.01262.x.pd

    Asymptotic statistics of the n-sided planar Poisson-Voronoi cell. I. Exact results

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    We achieve a detailed understanding of the nn-sided planar Poisson-Voronoi cell in the limit of large nn. Let p_n{p}\_n be the probability for a cell to have nn sides. We construct the asymptotic expansion of logp_n\log {p}\_n up to terms that vanish as nn\to\infty. We obtain the statistics of the lengths of the perimeter segments and of the angles between adjoining segments: to leading order as nn\to\infty, and after appropriate scaling, these become independent random variables whose laws we determine; and to next order in 1/n1/n they have nontrivial long range correlations whose expressions we provide. The nn-sided cell tends towards a circle of radius (n/4\pi\lambda)^{\half}, where λ\lambda is the cell density; hence Lewis' law for the average area A_nA\_n of the nn-sided cell behaves as A_ncn/λA\_n \simeq cn/\lambda with c=1/4c=1/4. For nn\to\infty the cell perimeter, expressed as a function R(ϕ)R(\phi) of the polar angle ϕ\phi, satisfies d2R/dϕ2=F(ϕ)d^2 R/d\phi^2 = F(\phi), where FF is known Gaussian noise; we deduce from it the probability law for the perimeter's long wavelength deviations from circularity. Many other quantities related to the asymptotic cell shape become accessible to calculation.Comment: 54 pages, 3 figure
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