2,002 research outputs found
Two-stage reusable launch system utilizing a winged core vehicle and glideback boosters
A near-term technology launch system is described in which Space Shuttle main engines are used on a manned orbiter and also on twin strap-on unmanned boosters. The orbiter has a circular body and clipped delta wings. The twin strap-on boosters have a circular body and deployable oblique wings for a glideback recovery. The dry and gross weights of the system, capable of delivering 70klb of cargo to orbit, are compared with a similar system with hydrocarbon-fueled boosters and with the current Shuttle
Dual therapy strategies for COPD: the scientific rationale for LAMA + LABA
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity, mortality, and health care expenditure worldwide. Relaxation of airway smooth muscle with inhaled bronchodilators is the cornerstone of treatment for stable COPD, with inhaled corticosteroids reserved for those with a history of exacerbations. Tiotropium has occupied center stage in COPD treatment for over 10 years and improves lung function, quality of life, exercise endurance, and reduces the risk of COPD exacerbation. Long-acting β2-agonists (LABAs) improve lung function, reduce dynamic hyperinflation, increase exercise tolerance, health-related quality of life, and reduce acute exacerbation of COPD. The combination of long-acting muscarinic antagonists (LAMAs) and LABAs is thought to leverage different pathways to induce bronchodilation using submaximal drug doses, increasing the benefits and minimizing receptor-specific side effects. Umeclidinium/vilanterol is the first combination of LAMA/LABA to be approved for use in stable COPD in USA and Europe. Additionally, indacaterol/glycopyrronium and aclidinium/formoterol have been approved in Europe and in numerous locations outside USA. Several other agents are in the late stages of development, most of which offer once-daily dosing. The benefits of new LAMA/LABA combinations include improved pulmonary function, dyspnea, and health-related quality of life, and in some cases, reduced exacerbations. These evolving treatments will provide new opportunities and challenges in the management of COPD
The outsourcing of social care in Britain : what does it mean for voluntary sector workers?
While recent decades have witnessed a growth in the outsourcing of public services in Britain, the post-1997 UK Labour governments have sought to put in place mechanisms aimed at encouraging long-term collaborative contracting relationships marked by less reliance on cost-based competition. This article explores empirically how far these mechanisms have achieved their aims and thereby acted to protect the employment conditions of staff, and links this exploration to debates concerning the employment implications of organizational reforms within public sectors internationally. It concludes that in terms of bringing income security to the voluntary sector and stability to employment terms and conditions these efforts have been unsuccessful, and consequently casts doubts on more optimistic interpretations of the employment effects of organizational restructuring in the British public sector
Bostonia: v. 64, no. 1
Founded in 1900, Bostonia magazine is Boston University's main alumni publication, which covers alumni and student life, as well as university activities, events, and programs
Predicting university performance in psychology: the role of previous performance and discipline-specific knowledge
Recent initiatives to enhance retention and widen participation ensure it is crucial to understand the factors that predict students' performance during their undergraduate degree. The present research used Structural Equation Modeling (SEM) to test three separate models that examined the extent to which British Psychology students' A-level entry qualifications predicted: (1) their performance in years 1-3 of their Psychology degree, and (2) their overall degree performance. Students' overall A-level entry qualifications positively predicted performance during their first year and overall degree performance, but negatively predicted their performance during their third year. Additionally, and more specifically, students' A-level entry qualifications in Psychology positively predicted performance in the first year only. Such findings have implications for admissions tutors, as well as for students who have not studied Psychology before but who are considering applying to do so at university
Entangled Bessel beams
Orbital angular momentum (OAM) entanglement is investigated in the
Bessel-Gauss (BG) basis. Having a readily adjustable radial scale, BG modes
provide a more favourable basis for OAM entanglement over Laguerre-Gaussian
(LG) modes. The OAM bandwidth in terms of BG modes can be increased by
selection of particular radial modes and leads to a flattening of the spectrum.
The flattening of the spectrum allows for higher entanglement. We demonstrate
increased entanglement in terms of BG modes by performing a Bell-type
experiment and violating the appropriate Clauser Horne Shimony Holt (CHSH)
inequality. In addition, we reconstruct the quantum state of BG modes entangled
in high-dimensions.Comment: 8 pages, 4 figure
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