281 research outputs found
ATAMM analysis tool
Diagnostics software for analyzing Algorithm to Architecture Mapping Model (ATAMM) based concurrent processing systems is presented. ATAMM is capable of modeling the execution of large grain algorithms on distributed data flow architectures. The tool graphically displays algorithm activities and processor activities for evaluation of the behavior and performance of an ATAMM based system. The tool's measurement capabilities indicate computing speed, throughput, concurrency, resource utilization, and overhead. Evaluations are performed on a simulated system using the software tool. The tool is used to estimate theoretical lower bound performance. Analysis results are shown to be comparable to the predictions
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Blow-up versus boundedness in a nonlocal and nonlinear Fokker-Planck equation
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Blow-up versus boundedness in a nonlocal and nonlinear Fokker--Planck equation
We consider a Fokker-Planck equation on a compact interval where, as a constraint, the first moment is a prescribed function of time. Eliminating the associated Lagrange multiplier one obtains nonlinear and nonlocal terms. After establishing suitable local existence results, we use the relative entropy as an energy functional. However, the time-dependent constraint leads to a source term such that a delicate analysis is needed to show that the dissipation terms are strong enough to control the work done by the constraint. We obtain global existence of solutions as long as the prescribed first moment stays in the interior of an interval. If the prescribed moment converges to a constant value inside the interior of the interval, then the solution stabilises to the unique steady state
ATAMM enhancement and multiprocessor performance evaluation
ATAMM (Algorithm To Architecture Mapping Model) enhancement and multiprocessor performance evaluation is discussed. The following topics are included: the ATAMM model; ATAMM enhancement; ADM (Advanced Development Model) implementation of ATAMM; and ATAMM support tools
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Session A9: To Fill or Not to Fill: Stream Simulation and Embedded Aquatic Organism Passage Structures
Abstract:
Throughout North America stream simulation and embedded / recessed culverts are used to facilitate the passage of aquatic organisms thru road stream crossings. Although the concept of naturelike streambeds inside these structures is widely embraced, the design methodology and construction practice varies widely between state and federal agencies. Much debate has occurred with one specific requirement, whether or not to place stream bed material inside these structures. Not placing bed material inside structures assumes on going sediment transport processes will fill the structure’s interior with streambed materials. This is assumed to be a cost saving measure from both a design and implementation standpoint. Recent research, monitoring, and historic installations provide evidence that not placing streambed material can produce deleterious effects to the stream and aquatic habitat, cause low flow barriers, may not retain bed material, and potentially cause long term structural failure. Conversely in some channel types or site condition infilling may not be necessary and produce satisfactory results. Casual mechanism of success and failure, stream impacts, and design considerations will be discussed along with recommendations for site specific conditions where infilling structures is required or allowing structures to fill naturally would be successful
Non-equilibrium thermodynamical principles for chemical reactions with mass-action kinetics
We study stochastic interacting particle systems that model chemical reaction networks on the micro scale, converging to the macroscopic Reaction Rate Equation. One abstraction level higher, we study the ensemble of such particle systems, converging to the corresponding Liouville transport equation. For both systems, we calculate the corresponding large deviations and show that under the condition of detailed balance, the large deviations induce a non-linear relation between thermodynamic fluxes and free energy driving force
Design Considerations for Embankment Protection During Road Overtopping Events
This report describes the research conducted by the University of Minnesota and project partners on roadway embankment overtopping by flood water. Roadway overtopping is a major safety concern for Minnesota transportation managers because of the potential for rapid soil erosion and mass wasting resulting in partial or complete failure of the roadway embankment. This multi-year research study focused on various aspects of the roadway embankment overtopping. A robust literature survey was performed to identify research, reports and other published knowledge that would inform the project. A field- based research campaign was developed with the goal of collecting data on the hydraulics associated with full-scale overtopping events. Finally, a series of laboratory experiments were conducted at the St. Anthony Falls Laboratory, University of Minnesota to study the hydraulic and erosional processes associated with embankment overtopping and in particular study of three slope protection techniques under overtopping flow. The largest component of the research project was the laboratory hydraulic testing, which focused on bare soil (base case) and three slope protection technologies. A full- scale laboratory facility was constructed to carry out the testing. Three erosion protection techniques were examined including 1) armored sod, 2) turf reinforcement mat, and 3) flexible concrete geogrid mat. Overtopping depths of up to 1-ft were used to determine the failure point of the protection technique and soil on both the 4h:1V and 6V:1H slopes. The full project report details the testing of each protection technique as well as observations and findings made during the testing
Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor
PrImary decompressive Craniectomy in AneurySmal Subarachnoid hemOrrhage (PICASSO) trial: study protocol for a randomized controlled trial
BACKGROUND: Poor-grade aneurysmal subarachnoid hemorrhage (SAH) is associated with poor neurological outcome and high mortality. A major factor influencing morbidity and mortality is brain swelling in the acute phase. Decompressive craniectomy (DC) is currently used as an option in order to reduce intractably elevated intracranial pressure (ICP). However, execution and optimal timing of DC remain unclear. METHODS: PICASSO resembles a multicentric, prospective, 1:1 randomized standard treatment-controlled trial which analyzes whether primary DC (pDC) performed within 24 h combined with the best medical treatment in patients with poor-grade SAH reduces mortality and severe disability in comparison to best medical treatment alone and secondary craniectomy as ultima ratio therapy for elevated ICP. Consecutive patients presenting with poor-grade SAH, defined as grade 4–5 according to the World Federation of Neurosurgical Societies (WFNS), will be screened for eligibility. Two hundred sixteen patients will be randomized to receive either pDC additional to best medical treatment or best medical treatment alone. The primary outcome is the clinical outcome according to the modified Rankin Scale (mRS) at 12 months, which is dichotomized to favorable (mRS 0–4) and unfavorable (mRS 5–6). Secondary outcomes include morbidity and mortality, time to death, length of intensive care unit (ICU) stay and hospital stay, quality of life, rate of secondary DC due to intractably elevated ICP, effect of size of DC on outcome, use of duraplasty, and complications of DC. DISCUSSION: This multicenter trial aims to generate the first confirmatory data in a controlled randomized fashion that pDC improves the outcome in a clinically relevant endpoint in poor-grade SAH patients. TRIAL REGISTRATION: DRKS DRKS00017650. Registered on 09 June 2019. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13063-022-06969-4
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