Processing of on-board recorded data for quick analysis of aircraft performance

A system of independent computer programs for the processing of digitized pulse code modulated (PCM) and frequency modulated (FM) data is described. Information is stored in a set of random files and accessed to produce both statistical and graphical output. The software system is designed primarily to present these reports within a twenty-four hour period for quick analysis of the helicopter's performance

A computer program to determine the possible daily release window for sky target experiments

A computer program is presented which is designed to determine the daily release window for sky target experiments. Factors considered in the program include: (1) target illumination by the sun at release time and during the tracking period; (2) look angle elevation above local horizon from each tracking station to the target; (3) solar depression angle from the local horizon of each tracking station during the experimental period after target release; (4) lunar depression angle from the local horizon of each tracking station during the experimental period after target release; and (5) total sky background brightness as seen from each tracking station while viewing the target. Program output is produced in both graphic and data form. Output data can be plotted for a single calendar month or year. The numerical values used to generate the plots are furnished to permit a more detailed review of the computed daily release windows

On Slip Bands Obtained by Tension on Aluminium Specimens

IN RECENT studies'- ' we have been able to reveal the fine structure of Slip hands : we could also, on the other hand, determine the influence of deformation hands and adjacent crystals on their structure. In the present paper our aim is to define the mutual relations existing bctwween micro-hardness and slip bands. We are also examining the influence exerted by dimensions of the specimen and state of initial perfection on the development of these slip hands during plastic deformation. To avoid any anibiguity, we are explaining below what we mean by the following phrases : "Kink band" : unhent zone consisting of two kink hands in opposite ends. "Kink band": in knee" zone of great curvature separating two unbent ,zones. "Deformation band" : kink band, kink hand in knee, secondary slip hand. "Slip line"' : intersection of the surface of the specimen and only one slip plane. "Slip band" ; grouping of parallel slip lines

Understanding the Economic Consequences of Shifting Trends in Population Health

The public economic burden of shifting trends in population health remains uncertain. Sustained increases in obesity, diabetes, and other diseases could reduce life expectancy − with a concomitant decrease in the public-sector's annuity burden − but these savings may be offset by worsening functional status, which increases health care spending, reduces labor supply, and increases public assistance. Using a microsimulation approach, we quantify the competing public-finance consequences of shifting trends in population health for medical care costs, labor supply, earnings, wealth, tax revenues, and government expenditures (including Social Security and income assistance). Together, the reduction in smoking and the rise in obesity have increased net public-sector liabilities by $430bn, or approximately 4% of the current debt burden. Larger effects are observed for specific public programs: annual spending is 10% higher in the Medicaid program, and 7% higher for Medicare.disability, health care costs, social security, microsimulation

International Differences in Longevity and Health and Their Economic Consequences

In 1975, 50 year-old Americans could expect to live slightly longer than their European counterparts. By 2005, American life expectancy at that age has diverged substantially compared to Europe. We find that this growing longevity gap is primarily the symptom of real declines in the health of near-elderly Americans, relative to their European peers. In particular, we use a microsimulation approach to project what US longevity would look like, if US health trends approximated those in Europe. We find that differences in health can explain most of the growing gap in remaining life expectancy. In addition, we quantify the public finance consequences of this deterioration in health. The model predicts that gradually moving American cohorts to the health status enjoyed by Europeans could save up to $1.1 trillion in discounted total health expenditures from 2004 to 2050.disability, mortality, international comparisons, microsimulation

Host plant mediates foraging behavior and mutual interference among adult Stethorus gilvifrons (Coleoptera: Coccinellidae) preying on Tetranychus urticae (Acari: Tetranychidae)

Citation: Bayoumy, M. H., Osman, M. A., & Michaud, J. P. (2014). Host plant mediates foraging behavior and mutual interference among adult Stethorus gilvifrons (Coleoptera: Coccinellidae) preying on Tetranychus urticae. Retrieved from http://krex.ksu.eduPhysical plant characteristics can influence predator foraging and their behavioral responses to each other. This study examined the searching efficiency and functional response of adult female Stethorus gilvifrons Mulsant foraging for Tetranychus urticae Koch (Acari: Tetranychidae) on castor bean, common bean, and cucumber leaves. Experiments conducted on leaf discs in arenas for 12 h revealed a type II functional response for S. gilvifrons on all host plants. Per capita searching efficiency and killing power decreased with increasing predator density on all plants, but most notably on common bean, the plant with the highest prey consumption rates, due to greater mutual interference. Attack rates were highest on common bean and lowest on castor bean, whereas handling times were shortest on common bean and longest on cucumber, such that the daily predation rate was maximal on common bean. Host plant interacted with predator and prey densities to affect searching efficiency and functional response, the differences in mite consumption among host plants increasing with predator and prey densities. The waxy layers of castor bean leaves and high trichome counts of cucumber leaves appeared to reduce predator foraging efficiency. Thus, the efficacy of S. gilvifrons against T. urticae is likely to be greatest on plants such as Phaeseolus vulgaris L. that have relatively smooth leaves

Sexualité des adolescents et sida: processus et négociations autour des relations sexuelles et du choix de la contraception

Cette étude a permis d'explorer, auprès d'adolescents de 16 à 20 ans, l'entrée dans la vie sexuelle et l'utilisation de contraception et de protection vis à vis des maladies sexuellement transmissibles en abordant les perceptions, les attitudes et les croyances qui y sont liées et en étudiant les interactions et les négociations entre les partenaires. Les résultats confirment un certain nombre d'informations déjà disponibles en Suisse et issues d'autres enquêtes auprès des adolescents. Mais ils apportent aussi des indications quelquefois inattendues sur des sujets non encore explorés par la recherche auprès des adolescents. [...] Par rapport à la plupart des enquêtes sur la sexualité des adolescents et la prévention du sida, elle s'attache à considérer les comportements sexuels dans une perspective biographique, à les situer dans leur contexte et à mettre en évidence les aspects relationnels des décisions prises en couple au cours des différentes relations. L'originalité de cette enquête tient d'une part au contenu du questionnaire qui apporte des informations non disponibles en Suisse jusqu'ici et d'autre part aux méthodes utilisées. [P. 5]]]> HIV Infections/prevention &amp; control ; Acquired Immunodeficiency Syndrome/prevention &amp; control; Sex Education ; Sexual Behavior ; Attitude to Health ; Adolescent ; Child ; Program Evaluation ; Condoms/utilization ; Health Knowledge, Attitudes, Practice ; Questionnaires ; Switzerland fre https://serval.unil.ch/resource/serval:BIB_1691.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_16916 info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_16916 info:eu-repo/semantics/submittedVersion info:eu-repo/semantics/openAccess Copying allowed only for non-profit organizations https://serval.unil.ch/disclaimer application/pdf oai:serval.unil.ch:BIB_16918 2022-05-07T01:11:13Z <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_16918 Chemitry and Pharmacology of Asian Plants and Validation of Phytopharmaceuticals, Proceedings of the IOCD - International Symposium Chulabhorn, M Hostettmann, K info:eu-repo/semantics/book book 2000 oai:serval.unil.ch:BIB_16919 2022-05-07T01:11:13Z <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_16919 The Fugu rubripes tyrosinase gene promoter targets transgene expression to pigment cells in the mouse. Camacho-Hübner, A Rossier, A Beermann, F info:eu-repo/semantics/article article 2000 Genesis, vol. 28, pp. 99-105 oai:serval.unil.ch:BIB_1691E41DA533 2022-05-07T01:11:13Z ehelvetica openaire documents phdthesis urnserval <oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd"> https://serval.unil.ch/notice/serval:BIB_1691E41DA533 Methylation of GpG Island promoters in uveal melanoma Moulin, A.-P. Université de Lausanne, Faculté de biologie et médecine info:eu-repo/semantics/doctoralThesis phdthesis 2008 <![CDATA[ABSTRACT : Background: Inactivation of tumour-related genes by promoter hypermethylation is a common epigenetic event in the development of a variety of tumours. Aim: To investigate in primary uveal melanoma the status of promoter methylation of genes thought to be involved in tumour development: p16, TIMP3, RASSF1, RARB, FHIT, hTERT and APC. Methods: Gene promoter methylation was studied by methylation-sensitive single-strand conformation analysis and dot-blot assay in a series of 23 primary uveal melanomas. All DNA samples were obtained from paraffin-embedded formalin-fixed tissue blocks. Results: hTERT promoter methylation was found with a relatively high frequency (52%). Promoter methylation of p16, TIMP3, RASSF1, RARB, FHIT and APC was a rare event. For none of these genes did promoter methylation exceed 15% of tumour samples, and, for some genes (FHIT and APC), no methylation was found at all. Furthermore, promoter methylation was absent in 39% (9/ 23) of cases. In only 22% (5/23) of cases was hypermethylation of at least two promoters observed. Conclusions: Promoter methylation of hTERT is a regular event in uveal melanoma. Hypermethylation of the other genes studied does not seem to be an essential element in the development of this tumour. As promoter methylation of APC, RASSF1 and RARB is often observed in cutaneous melanoma, these results suggest that different epigenetic events occur in the development of cutaneous and uveal melanoma. RAPPORT DE SYNTHESE : L'inactivation de gènes par une hyperméthylation de leur promoteur apparaît être un événement épigénétique fréquent, se retrouvant dans de nombreuses tumeurs. Dans cette étude, nous avons investigué dans des mélanomes primaires de l'uvée l'état de méthylation du promoteur de gènes fréquemment impliqués dans le développent tumoral tels que p16, TIMP3, RASSFI, RARB, FHIT, hTERT et APC. La méthylation des promoteurs de gènes a été étudiée par methylationsensitive single-strand conformation analysis (MS-SSCA) et dot blot assay (MS-DBA) dans une série de 23 mélanomes primaires de l'uvée. Tous les échantillons tissulaires provenaient de matériel fixé dans le formol et conservé dans des blocs de parraffine. Nous avons identifié une fréquence relativement élevée (52%) pour la méthylation du promoteur de hTERT. En ce qui concerne le reste des gènes étudiés, nous avons retrouvé des fréquences de méthylation de promoteurs relativement basses avec 13% pour RASSF1, 13% pour RARB 13%, 9% pour TIMP3 et 4% pour p16. Nous n'avons pas retrouvé d'hyperméthylation des promoteurs des gènes APC et FRIT. La méthylation de hTERT apparaît être un événement important dans la biologie du mélanome de l'uvée. L'hyperméthylation des autres gènes évalués ne semble pas être cruciale dans le développent de cette tumeur. Comme la méthylation des promoteurs des gènes APC, RASSF1 et RARB a été fréquemment observée dans le mélanome de la peau, notre étude tend à démontrer que des mécanismes épigénétiques différents surviennent dans le développement respectif de ces tumeurs

Xylem surfactants introduce a new element to the cohesion-tension theory

Vascular plants transport water under negative pressure without constantly creating gas bubbles that would disable their hydraulic systems. Attempts to replicate this feat in artificial systems almost invariably result in bubble formation, except under highly controlled conditions with pure water and only hydrophilic surfaces present. In theory, conditions in the xylem should favor bubble nucleation even more: there are millions of conduits with at least some hydrophobic surfaces, and xylem sap is saturated or sometimes supersaturated with atmospheric gas and may contain surface-active molecules that can lower surface tension. So how do plants transport water under negative pressure? Here, we show that angiosperm xylem contains abundant hydrophobic surfaces as well as insoluble lipid surfactants, including phospholipids, and proteins, a composition similar to pulmonary surfactants. Lipid surfactants were found in xylem sap and as nanoparticles under transmission electron microscopy in pores of intervessel pit membranes and deposited on vessel wall surfaces. Nanoparticles observed in xylem sap via nanoparticle-tracking analysis included surfactant-coated nanobubbles when examined by freeze-fracture electron microscopy. Based on their fracture behavior, this technique is able to distinguish between dense-core particles, liquid-filled, bilayer-coated vesicles/liposomes, and gas-filled bubbles. Xylem surfactants showed strong surface activity that reduces surface tension to low values when concentrated as they are in pit membrane pores. We hypothesize that xylem surfactants support water transport under negative pressure as explained by the cohesion-tension theory by coating hydrophobic surfaces and nanobubbles, thereby keeping the latter below the critical size at which bubbles would expand to form embolisms

Molecular autopsy in sudden cardiac death and its implication for families: discussion of the practical, legal and ethical aspects of the multidisciplinary collaboration.

Sudden cardiac death (SCD) is a major cause of premature death in young adults and children in developed countries. Standard forensic autopsy procedures are often unsuccessful in determining the cause of SCD. Post-mortem genetic testing, also called molecular autopsy, has revealed that a non-negligible number of these deaths are a result of inherited cardiac diseases, including arrhythmic disorders such as congenital long QT syndrome and Brugada syndrome. Due to the heritability of these diseases, the potential implications for living relatives must be taken into consideration. Advanced diagnostic analyses, genetic counselling, and interdisciplinary collaboration should be integral parts of clinical and forensic practice. In this article we present a multidisciplinary collaboration established in Lausanne, with the goal of properly informing families of these pathologies and their implications for surviving family members. In Switzerland, as in many other countries, legal guidelines for genetic testing do not address the use of molecular tools for post-mortem genetic analyses in forensic practice. In this article we present the standard practice guidelines established by our multidisciplinary team

A Renaissance study of Am stars. I. The mass ratio distribution

Triggered by the study of Carquillat & Prieur (2007, MNRAS, 380, 1064) of Am binaries, I reanalyse their sample of 60 orbits to derive the mass ratio distribution (MRD), assuming as they did a priori functional forms, i.e. a power law or a Gaussian. The sample is then extended using orbits published by several groups and a full analysis of the MRD is made, without any assumption on the functional form. I derive the MRD using a Richardson-Lucy inversion method, assuming a fixed mass of the Am primary and randomly distributed orbital inclinations. Using the large sub-sample of double-lined spectroscopic binaries, I show that this methodology is indeed perfectly adequate. Using the inversion method, applied to my extended sample of 162 systems, I find that the final MRD can be approximated by a uniform distribution.Comment: 7 pages, 9 figures; Accepted by A&