186 research outputs found

    Not a Matter of Interpretation

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    This Article explores the basic question of statutory interpretation. The disagreement among scholars is a theoretical one - it is a dispute about what the proper object of interpretation should be, about whether it should be what Scalia calls the objective indication of the words (what the authors said), or whether it should be the intent of the legislature (what the authors meant)

    Educational Impact on Therapists’ Knowledge, Beliefs, and Actions: A Pilot Study

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    ABSTRACT Purpose: Collaborative goal setting has been shown to be an effective way to promote client engagement leading to improved outcomes; however, healthcare professionals face challenges when implementing collaborative goal setting into their clinical practice. The purpose of this study was to evaluate the effectiveness of educational workshops to 1) increase a therapist’s knowledge of motivational interviewing and action planning, 2) promote collaboration between therapists and their patients/clients, 3) promote collaboration between therapists and their interdisciplinary team and 4) increase the ease of implementation of motivational interviewing and action planning skills into a therapist’s clinical practice. Method: A mixed-methods design was utilized. Occupational therapists and physical therapists were recruited via email to participate. Data were collected via online surveys at three different times (before the first educational workshop, after the second workshop, and three months after the second workshop) consisting of quantitative related survey questions assessing the participants’ knowledge, beliefs, actions, and perceived self-efficacy related to motivational interviewing and action planning and qualitative questions focused on typical goal development processes, level of collaboration and challenges associated with developing goals with clients and interdisciplinary team members and anticipated/resultant impact and meaning of participation in the educational workshops. Results: The sample included 19 participants. Quantitative data demonstrated a statistically significant increase in self-scoring related to knowledge, beliefs, and actions when comparing all the pre-education to the post-education scores, except for one (collaboration with interdisciplinary team members). A follow-up analysis on this criterion demonstrated no statistically significant changes over the three-month period, potentially indicative of retention of the material covered. The qualitative data provided further insight into the challenges faced by participants and the perceived benefits of participating in the educational workshops. Conclusion: The educational workshops appeared to be effective in addressing some of the barriers to collaborative goal setting (e.g. lack of time, knowledge/skills, appropriate patients, concern for duplication of services) found in the literature, most notably providing the participants with the knowledge and skills needed, which is the first step when implementing collaborative goal setting into clinical practice. Further research in this area is recommended

    ATXR5 and ATXR6 are H3K27 monomethyltransferases required for chromatin structure and gene silencing.

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    Constitutive heterochromatin in Arabidopsis thaliana is marked by repressive chromatin modifications, including DNA methylation, histone H3 dimethylation at Lys9 (H3K9me2) and monomethylation at Lys27 (H3K27me1). The enzymes catalyzing DNA methylation and H3K9me2 have been identified; alterations in these proteins lead to reactivation of silenced heterochromatic elements. The enzymes responsible for heterochromatic H3K27me1, in contrast, remain unknown. Here we show that the divergent SET-domain proteins ARABIDOPSIS TRITHORAX-RELATED PROTEIN 5 (ATXR5) and ATXR6 have H3K27 monomethyltransferase activity, and atxr5 atxr6 double mutants have reduced H3K27me1 in vivo and show partial heterochromatin decondensation. Mutations in atxr5 and atxr6 also lead to transcriptional activation of repressed heterochromatic elements. Notably, H3K9me2 and DNA methylation are unaffected in double mutants. These results indicate that ATXR5 and ATXR6 form a new class of H3K27 methyltransferases and that H3K27me1 represents a previously uncharacterized pathway required for transcriptional repression in Arabidopsis

    Observation of an oxygen isotope effect in YBa\u3csub\u3e2\u3c/sub\u3eCu\u3csub\u3e3\u3c/sub\u3eO\u3csub\u3e7\u3c/sub\u3e

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    A small decrease in Tc of 0.3 K to 0.5 K is observed when as much as 90% of the 16O in YBa2Cu3O7 is substituted with18O. This result is consistent with our observation that there is an oxygen isotope effect in La1.85Sr0.15CuO4, but in contrast with previous reports that there is no isotope effect for YBa2Cu3O7. This new result suggests that phonons play an important role in the electron-pairing mechanism in YBa2Cu3O7

    Observation of an Isotope Shift in the Superconducting Transition Temperature of La\u3csub\u3e1.85\u3c/sub\u3eSr\u3csub\u3e0.15\u3c/sub\u3eCuO\u3csub\u3e4\u3c/sub\u3e

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    An oxygen isotope shift is observed in superconducting La1.85Sr0.15CuO4 when 18O is substituted partially for 16O; the superconducting transition temperature Tc is lowered by 0.3 to 1.0 K in different samples. We examine these results using conventioanl phonon-mediated BCS theory and conclude that, for La1.85Sr0.15CuO4, phonons play an important role in the pairing mechanism
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