Software Sustainability: The Modern Tower of Babel

<p>The aim of this paper is to explore the emerging definitions of software sustainability from the field of software engineering in order to contribute to the question, what is software sustainability?</p

Scenario-based design and evaluation for capability

Scenarios are frequently used within techniques for planning and designing systems. They are an especially helpful means of visualizing and understanding the incorporation of new systems within systems of systems. If used as the basis for decisions about candidate designs, then it is important that such decisions can be rationalized and quantitative assessment is particularly important. In this paper, an approach for developing complex scenarios, which incorporates the phases of systems development and deployment, is presented and a quantitative method of comparison is described. This approach is based on the development of measures of merit and measures of performance. The techniques are illustrated using cases that are relevant to Network Enabled Capability

Blazars in the Fermi Era: The OVRO 40-m Telescope Monitoring Program

The Large Area Telescope (LAT) aboard the Fermi Gamma-ray Space Telescope provides an unprecedented opportunity to study gamma-ray blazars. To capitalize on this opportunity, beginning in late 2007, about a year before the start of LAT science operations, we began a large-scale, fast-cadence 15 GHz radio monitoring program with the 40-m telescope at the Owens Valley Radio Observatory (OVRO). This program began with the 1158 northern (declination>-20 deg) sources from the Candidate Gamma-ray Blazar Survey (CGRaBS) and now encompasses over 1500 sources, each observed twice per week with a ~4 mJy (minimum) and 3% (typical) uncertainty. Here, we describe this monitoring program and our methods, and present radio light curves from the first two years (2008 and 2009). As a first application, we combine these data with a novel measure of light curve variability amplitude, the intrinsic modulation index, through a likelihood analysis to examine the variability properties of subpopulations of our sample. We demonstrate that, with high significance (7-sigma), gamma-ray-loud blazars detected by the LAT during its first 11 months of operation vary with about a factor of two greater amplitude than do the gamma-ray-quiet blazars in our sample. We also find a significant (3-sigma) difference between variability amplitude in BL Lacertae objects and flat-spectrum radio quasars (FSRQs), with the former exhibiting larger variability amplitudes. Finally, low-redshift (z<1) FSRQs are found to vary more strongly than high-redshift FSRQs, with 3-sigma significance. These findings represent an important step toward understanding why some blazars emit gamma-rays while others, with apparently similar properties, remain silent.Comment: 23 pages, 24 figures. Submitted to ApJ

Energetic Particles of Cosmic Accelerators I: Galactic Accelerators

The high-energy universe has revealed that energetic particles are ubiquitous in the cosmos and play a vital role in the cultivation of cosmic environments on all scales. Our pursuit of more than a century to uncover the origins and fate of these cosmic energetic particles has given rise to some of the most interesting and challenging questions in astrophysics. Energetic particles in our own galaxy, galactic cosmic rays (GCRs), engage in a complex interplay with the interstellar medium and magnetic fields in the galaxy, giving rise to many of its key characteristics. For instance, GCRs act in concert with galactic magnetic fields to support its disk against its own weight. GCR ionization and heating are essential ingredients in promoting and regulating the formation of stars and protostellar disks. GCR ionization also drives astrochemistry, leading to the build up of complex molecules in the interstellar medium. GCR transport throughout the galaxy generates and maintains turbulence in the interstellar medium, alters its multi-phase structure, and amplifies magnetic fields. GCRs could even launch galactic winds that enrich the circumgalactic medium and alter the structure and evolution of galactic disks. As crucial as they are for many of the varied phenomena in our galaxy, there is still much we do not understand about GCRs. While they have been linked to supernova remnants (SNRs), it remains unclear whether these objects can fully account for their entire population, particularly at the lower (approximately less than 1 GeV per nucleon) and higher (~PeV) ends of the spectrum. In fact, it is entirely possible that the SNRs that have been found to accelerate CRs merely re-accelerate them, leaving the origins of the original GCRs a mystery. The conditions for particle acceleration that make SNRs compelling source candidates are also likely to be present in sources such as protostellar jets, superbubbles, and colliding wind binaries (CWBs), but we have yet to ascertain their roles in producing GCRs. For that matter, key details of diffusive shock acceleration (DSA) have yet to be revealed, and it remains to be seen whether DSA can adequately explain particle acceleration in the cosmos. This White Paper is the first of a two-part series highlighting the most well-known high-energy cosmic accelerators and contributions that MeV gamma-ray astronomy will bring to understanding their energetic particle phenomena. For the case of GCRs, MeV astronomy will: 1) Search for fresh acceleration of GCRs in SNRs; 2) Test the DSA process, particularly in SNRs and CWBs; 3) Search for signs of CR acceleration in protostellar jets and superbubbles

Scenario-based design and evaluation for capability

Scenarios are frequently used within techniques for planning and designing systems. They are an especially helpful means of visualizing and understanding the incorporation of new systems within systems of systems. If used as the basis for decisions about candidate designs, then it is important that such decisions can be rationalized and quantitative assessment is particularly important. In this paper, an approach for developing complex scenarios, which incorporates the phases of systems development and deployment, is presented and a quantitative method of comparison is described. This approach is based on the development of measures of merit and measures of performance. The techniques are illustrated using cases that are relevant to Network Enabled Capability

Energetic Particles of Cosmic Accelerators II: Active Galactic Nuclei and Gamma-ray Bursts

The high-energy universe has revealed that energetic particles are ubiquitous in the cosmos and play a vital role in the cultivation of cosmic environments on all scales. Though they play a key role in cultivating the cosmological environment and/or enabling our studies of it, there is still much we do not know about AGNs and GRBs, particularly the avenue in which and through which they supply radiation and energetic particles, namely their jets. This White Paper is the second of a two-part series highlighting the most well-known high-energy cosmic accelerators and contributions that MeV gamma-ray astronomy will bring to understanding their energetic particle phenomena. The focus of this white paper is active galactic nuclei and gamma-ray bursts.Comment: 11 pages (including references), 2 figures; Submitted to the Astro2020 call for science white paper

Catching Element Formation In The Act

Gamma-ray astronomy explores the most energetic photons in nature to address some of the most pressing puzzles in contemporary astrophysics. It encompasses a wide range of objects and phenomena: stars, supernovae, novae, neutron stars, stellar-mass black holes, nucleosynthesis, the interstellar medium, cosmic rays and relativistic-particle acceleration, and the evolution of galaxies. MeV gamma-rays provide a unique probe of nuclear processes in astronomy, directly measuring radioactive decay, nuclear de-excitation, and positron annihilation. The substantial information carried by gamma-ray photons allows us to see deeper into these objects, the bulk of the power is often emitted at gamma-ray energies, and radioactivity provides a natural physical clock that adds unique information. New science will be driven by time-domain population studies at gamma-ray energies. This science is enabled by next-generation gamma-ray instruments with one to two orders of magnitude better sensitivity, larger sky coverage, and faster cadence than all previous gamma-ray instruments. This transformative capability permits: (a) the accurate identification of the gamma-ray emitting objects and correlations with observations taken at other wavelengths and with other messengers; (b) construction of new gamma-ray maps of the Milky Way and other nearby galaxies where extended regions are distinguished from point sources; and (c) considerable serendipitous science of scarce events -- nearby neutron star mergers, for example. Advances in technology push the performance of new gamma-ray instruments to address a wide set of astrophysical questions.Comment: 14 pages including 3 figure

Genome-Wide Functional Profiling Reveals Genes Required for Tolerance to Benzene Metabolites in Yeast

Benzene is a ubiquitous environmental contaminant and is widely used in industry. Exposure to benzene causes a number of serious health problems, including blood disorders and leukemia. Benzene undergoes complex metabolism in humans, making mechanistic determination of benzene toxicity difficult. We used a functional genomics approach to identify the genes that modulate the cellular toxicity of three of the phenolic metabolites of benzene, hydroquinone (HQ), catechol (CAT) and 1,2,4-benzenetriol (BT), in the model eukaryote Saccharomyces cerevisiae. Benzene metabolites generate oxidative and cytoskeletal stress, and tolerance requires correct regulation of iron homeostasis and the vacuolar ATPase. We have identified a conserved bZIP transcription factor, Yap3p, as important for a HQ-specific response pathway, as well as two genes that encode putative NAD(P)H:quinone oxidoreductases, PST2 and YCP4. Many of the yeast genes identified have human orthologs that may modulate human benzene toxicity in a similar manner and could play a role in benzene exposure-related disease

All-sky Medium Energy Gamma-ray Observatory: Exploring the Extreme Multimessenger Universe

The All-sky Medium Energy Gamma-ray Observatory (AMEGO) is a probe class mission concept that will provide essential contributions to multimessenger astrophysics in the late 2020s and beyond. AMEGO combines high sensitivity in the 200 keV to 10 GeV energy range with a wide field of view, good spectral resolution, and polarization sensitivity. Therefore, AMEGO is key in the study of multimessenger astrophysical objects that have unique signatures in the gamma-ray regime, such as neutron star mergers, supernovae, and flaring active galactic nuclei. The order-of-magnitude improvement compared to previous MeV missions also enables discoveries of a wide range of phenomena whose energy output peaks in the relatively unexplored medium-energy gamma-ray band