505 research outputs found

    Agencyā€”Principal Held Notified Through Agent Acting for Both Seller and Purchaser of Real Property

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    Farr v. Newman, 14 N.Y.2d 183, 199 N.E.2d 369, 250 N.Y.S.2d 272 (1964)

    Municipal Corporationsā€”Fellow Servant Rule Not a Valid Defense to Liability of City for Negligence of Its Employee in Operating a Municipal Vehicle

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    Poniatowski v. City of New York, 14 N.Y.2d 76, 198 N.E.2d 237, 248 N.Y.S.2d 849 (1964)

    Global Perspectives on Democracy and Public Stadium Finance

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    Arenas, ballparks, and stadiums built for professional sports teams or mega-events all around the world often come with large public costs. In democratic states, citizens are assumed to have a role in public policymaking, but previous research suggests the strength of this role can vary case-to-case. To examine the incidence of public stadium finance and public participation across the geopolitical landscape, a collective case study was employed and organized into regime type (i.e., full democracies, flawed democracies, hybrid regimes, authoritarian regimes). The results of the study show clear contrasts in the financing mechanisms within and between regime types. Additionally, each case-study grouping contained examples of citizen-led public participation, though the efficacy of these democratic actions is questionable. This review complements the growing literature on public policy and stadium finance by assessing public engagement in current stadium-subsidy debates around the world

    Maximum and minimum toughness of graphs of small genus

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    AbstractA new lower bound on the toughness t(G) of a graph G in terms of its connectivity Ļ°(G) and genus Ī³(G) is obtained. For Ī³ > 0, the bound is sharp via an infinite class of extremal graphs all of girth 4. For planar graphs, the bound is t(G) > Ļ°(G)/2 āˆ’ 1. For Ļ° = 1 this bound is not sharp, but for each Ļ° = 3, 4, 5 and any Ļµ > 0, infinite families of graphs {G(Ļ°, Ļµ)} are provided with Ļ°(G(Ļ°, Ļµ)) = Ļ°, but t(G(Ļ°, Ļµ)) < Ļ°/2 āˆ’ 1 + Ļµ.Analogous investigations on the torus are carried out, and finally the question of upper bounds is discussed. Several unanswered questions are posed

    Efficient generation of vesicular stomatitis virus (VSV)-pseudotypes bearing morbilliviral glycoproteins and their use in quantifying virus neutralising antibodies

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    Morbillivirus neutralising antibodies are traditionally measured using either plaque reduction neutralisation tests (PRNTs) or live virus microneutralisation tests (micro-NTs). While both test formats provide a reliable assessment of the strength and specificity of the humoral response, they are restricted by the limited number of viral strains that can be studied and often present significant biological safety concerns to the operator. In this study, we describe the adaptation of a replication-defective vesicular stomatitis virus (VSVĪ”G) based pseudotyping system for the measurement of morbillivirus neutralising antibodies. By expressing the haemagglutinin (H) and fusion (F) proteins of canine distemper virus (CDV) on VSVĪ”G pseudotypes bearing a luciferase marker gene, neutralising antibody titres could be measured rapidly and with high sensitivity. Further, by exchanging the glycoprotein expression construct, responses against distinct viral strains or species may be measured. Using this technique, we demonstrate cross neutralisation between CDV and peste des petits ruminants virus (PPRV). As an example of the value of the technique, we demonstrate that UK dogs vary in the breadth of immunity induced by CDV vaccination; in some dogs the neutralising response is CDV-specific while, in others, the neutralising response extends to the ruminant morbillivirus PPRV. This technique will facilitate a comprehensive comparison of cross-neutralisation to be conducted across the morbilliviruses
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