66 research outputs found
Cryogenic Characterization of Commercial SiC Power MOSFETs
The cryogenic performance of two commercially available SiC power MOSFETs are presented in this work. The devices are characterised in static and dynamic tests at 10 K intervals from 20-320 K. Static current-voltage characterisation indicates that at low temperatures threshold voltage, turn-on voltage, on-state resistance, transconductance, and the body diode turn-on voltage all increase while saturation current decreases. Dynamic, 60 V, 3A switching tests within the cryogenic chamber are also reported and the trends of switching speed, losses, and total power losses, which rise at low temperature, are presented. Overall, both MOSFETs are fully operable down to 20 K with both positive and negative changes in behaviour.</p
Quantum magneto-oscillations in a two-dimensional Fermi liquid
Quantum magneto-oscillations provide a powerfull tool for quantifying
Fermi-liquid parameters of metals. In particular, the quasiparticle effective
mass and spin susceptibility are extracted from the experiment using the
Lifshitz-Kosevich formula, derived under the assumption that the properties of
the system in a non-zero magnetic field are determined uniquely by the
zero-field Fermi-liquid state. This assumption is valid in 3D but, generally
speaking, erroneous in 2D where the Lifshitz-Kosevich formula may be applied
only if the oscillations are strongly damped by thermal smearing and disorder.
In this work, the effects of interactions and disorder on the amplitude of
magneto-oscillations in 2D are studied. It is found that the effective mass
diverges logarithmically with decreasing temperature signaling a deviation from
the Fermi-liquid behavior. It is also shown that the quasiparticle lifetime due
to inelastic interactions does not enter the oscillation amplitude, although
these interactions do renormalize the effective mass. This result provides a
generalization of the Fowler-Prange theorem formulated originally for the
electron-phonon interaction.Comment: 4 pages, 1 figur
Inter-Laboratory Robustness of Next-Generation Bile Acid Study in Mice and Humans: International Ring Trial Involving 12 Laboratories
Abstract
Background
The increasing relevance of individual bile acids quantification in biological samples requires analytical standardization to guarantee robustness and reliability of laboratory results. We have organized the first international ring trial, carried out in 12 laboratories, to evaluate the newly developed LC-MS/MSâbased test kit for bile acid analysis.
Methods
Each laboratory received a BiocratesÂź Bile Acids Kit including system suitability test (SST) protocol. The kit is designed to analyze 16 individual human and 19 mouse bile acids. A set of 9 human and mouse plasma samples was measured in replicates. Laboratories were first required to pass the acceptance criteria for the SST. Within the subset of laboratories passing SST criteria, we evaluated how many laboratories met the target criteria of 80% of reported values with a relative accuracy within the 70%â130% range and analytical precisions (%CV) below 30%.
Results
A total of 12 of 16 participating laboratories passed the SST as the prerequisite to enter the ring trial. All 12 laboratories were then able to successfully run the kit and ring trial samples. Of the overall reported values, 94% were within 70%â130% relative accuracy range. Mean precision was 8.3% CV. The condition of CV <30% was fulfilled by 99% of the reported values.
Conclusions
The first publically available interlaboratory ring trial for standardized bile acids quantification in human and mouse plasma samples showed very good analytical performance, within acceptance criteria typically applied in the preclinical environment. The kit is therefore suitable for standardized quantitative bile acid analysis and the establishment of reference values
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A protocol for an intercomparison of biodiversity and ecosystem services models using harmonized land-use and climate scenarios
To support the assessments of the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES), the IPBES Expert Group on Scenarios and Models is carrying out an intercomparison of biodiversity and ecosystem services models using harmonized scenarios (BES-SIM). The goals of BES-SIM are (1) to project the global impacts of land-use and climate change on biodiversity and ecosystem services (i.e., nature's contributions to people) over the coming decades, compared to the 20th century, using a set of common metrics at multiple scales, and (2) to identify model uncertainties and research gaps through the comparisons of projected biodiversity and ecosystem services across models. BES-SIM uses three scenarios combining specific Shared Socio-economic Pathways (SSPs) and Representative Concentration Pathways (RCPs)-SSP1xRCP2.6, SSP3xRCP6.0, SSP5xRCP8.6-to explore a wide range of land-use change and climate change futures. This paper describes the rationale for scenario selection, the process of harmonizing input data for land use, based on the second phase of the Land Use Harmonization Project (LUH2), and climate, the biodiversity and ecosystem services models used, the core simulations carried out, the harmonization of the model output metrics, and the treatment of uncertainty. The results of this collaborative modeling project will support the ongoing global assessment of IPBES, strengthen ties between IPBES and the Intergovernmental Panel on Climate Change (IPCC) scenarios and modeling processes, advise the Convention on Biological Diversity (CBD) on its development of a post-2020 strategic plans and conservation goals, and inform the development of a new generation of nature-centred scenarios
Synthesizing the scientific evidence to inform the development of the post-2020 Global Framework on Biodiversity
Fil: DĂaz, Sandra. Universidad Nacional de CĂłrdoba; Argentina.Fil: Broadgate, Wendy. Future Earth; Suecia.Fil: Declerck, Fabrice. Bioversity International; Italia.Fil: Dobrota, Susanna. Future Earth; Suecia.Fil: Krug, Cornelia. bioDISCOVERY; Suecia.Fil: Moersberg, Hannah. Future Earth; Francia.Fil: Obura, David. Coastal Oceans Research and Development â Indian Ocean; Kenya.Fil: Spehn, Eva. Forum Biodiversity; Suiza.Fil: Tewksbury, Joshua. Future Earth; Estados Unidos.Fil: Verburg, Peter. Vrije Universiteit Amsterdam; PaĂses Bajos.Fil: Zafra Calvo, Noelia. Future Earth; Suecia.Fil: Bellon, Mauricio. ComisiĂłn Nacional para el Conocimiento y Uso de la Biodiversidad; MĂ©xico.Fil: Burgess, Neil. United Nations Environment Programme World Conservation Monitoring Centre; Reino Unido.Fil: Cariño, Joji. Forest Peoples Programme; Reino Unido.Fil: Castañeda Alvarez, Nora. Global Crop Diversity Trust; Alemania.Fil: Cavender-Bares, Jeannine. University of Minnesota; Estados Unidos.Fil: Chaplin Kramer, Rebecca. Stanford University; Estados Unidos.Fil: De Meester, Luc. Katholieke Universiteit Leuven; BĂ©lgica.Fil: Dulloo, Ehsan. Consultative Group for International Agricultural Research; Francia.Fil: FernĂĄndez-Palacios, JosĂ© MarĂa. Universidad de La Laguna; España.Fil: Garibaldi, Lucas A. Universidad Nacional de RĂo Negro. Instituto de Investigaciones en Recursos Naturales, AgroecologĂa y Desarrollo Rural; Argentina.Fil: Garibaldi, Lucas A. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Instituto de Investigaciones en Recursos Naturales, AgroecologĂa y Desarrollo Rural; Argentina.Fil: Hill, Samantha. United Nations Environment Programme World Conservation Monitoring Centre; Reino Unido.Fil: Isbell, Forest. University of Minnesota; Estados Unidos.Fil: Leadley, Paul. UniversitĂ© Paris-Saclay; Francia.Fil: Liu, Jianguo. Michigan State University; Estados Unidos.Fil: Mace, Georgina M. University College London; Reino Unido.Fil: Maron, Martine. The University of Queensland; Australia.Fil: MartĂn-LĂłpez, Berta. Leuphana University LĂŒneburg; Alemania.Fil: McGowan, Philip. University of Newcastle; Australia.Fil: Pereira, Henrique. German Centre for Integrative Biodiversity Research; Alemania.Fil: Purvis, Andy. Imperial College London. Grand Challenges in Ecosystems and the Environment; Reino Unido.Fil: Reyes-GarcĂa, Victoria. Universidad AutĂłnoma de Barcelona; España.Fil: Rocha, Juan. Future Earth; Suecia.Fil: Rondinini, Carlo. Sapienza-UniversitĂ di Roma; Italia.Fil: Shannon, Lynne. University of Cape Town; SudĂĄfrica.Fil: Shaw, Rebecca. World Wildlife Fund; Estados Unidos.Fil: Shin, Yunne Jai. University of Cape Town. Marine Research Institute. Department of Biological Sciences; SudĂĄfrica.Fil: Snelgrove, Paul. Memorial University of Newfoundland; CanadĂĄ.Fil: Strassburg, Bernardo. International Institute for Sustainability; Brasil.Fil: Subramanian, Suneetha.United Nations University; JapĂłn.Fil: Visconti, Piero. International Institute for Applied Systems Analysis; Austria.Fil: Watson, James. Wildlife Conservation Society; Estados Unidos.Fil: Zanne, Amy. The George Washington University; Estados Unidos.Fil: Bruford, Michael. Cardiff University; Gales.Fil: Colli, Licia. UniversitĂ Cattolica del Sacro Cuore; Italia.Fil: Azeredo de Dornelas, Maria. University of St Andrews; Escocia.Fil: Bascompte, Jordi. UniversitĂ€t ZĂŒrich; Suiza.Fil: Forest, Felix. Royal Botanic Gardens; Reino Unido.Fil: Hoban, Sean. The Morton Arboretum; Estados Unidos.Fil: Jones, Sarah. Consultative Group for International Agricultural Research; Francia.Fil: Jordano, Pedro. Consejo Superior de Investigaciones CientĂficas; España.Fil: Kassen, Rees. University of Ottawa; CanadĂĄ.Fil: Khoury, Colin. Consultative Group for International Agricultural Research; Francia.Fil: Laikre, Linda. Stockholms Universitet; Suecia.Fil: Maxted, Nigel. University of Birmingham; Reino Unido.Fil: Miloslavich, Patricia. Universidad SimĂłn BolĂvar; Venezuela.Fil: Moreno Mateos, David. Basque Centre for Climate Change; España.Fil: Ogden, Rob. The University of Edinburgh; Reino Unido.Fil: Segelbacher, Gernot. Albert-Ludwigs-UniversitĂ€t Freiburg; Alemania.Fil: Souffreau, Caroline. Katholieke Universiteit Leuven; BĂ©lgica.Fil: Svenning, Jens Christian. Aarhus University; Dinamarca.Fil: VĂĄzquez, Ella. Universidad Nacional AutĂłnoma de MĂ©xico; MĂ©xico.This report is the result of a meeting which aimed to offer scientific guidance to the development under the Convention on Biological Diversity (CBD) of the post-2020 Global Biodiversity Framework focussing on its contribution to the 2030 Mission and 2050 Vision. We provide a synthesis of the scientific and technical justification, evidence base and feasibility for outcome-oriented goals on nature and its contributions to people, including biodiversity at different levels from genes to biomes. The report is structured to respond to the Zero Draft of the post-2020 Global Biodiversity Framework
TRY plant trait database â enhanced coverage and open access
Plant traits - the morphological, anatomical, physiological, biochemical and phenological characteristics of plants - determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of traitâbased plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits - almost complete coverage for âplant growth formâ. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and traitâenvironmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives
TRY plant trait database â enhanced coverage and open access
Plant traitsâthe morphological, anatomical, physiological, biochemical and phenological characteristics of plantsâdetermine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait-based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traitsâalmost complete coverage for âplant growth formâ. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and traitâenvironmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives.Rest of authors: Decky Junaedi, Robert R. Junker, Eric Justes, Richard Kabzems, Jeffrey Kane, Zdenek Kaplan, Teja Kattenborn, Lyudmila Kavelenova, Elizabeth Kearsley, Anne Kempel, Tanaka Kenzo, Andrew Kerkhoff, Mohammed I. Khalil, Nicole L. Kinlock, Wilm Daniel Kissling, Kaoru Kitajima, Thomas Kitzberger, Rasmus KjĂžller, Tamir Klein, Michael Kleyer, Jitka KlimeĆĄovĂĄ, Joice Klipel, Brian Kloeppel, Stefan Klotz, Johannes M. H. Knops, Takashi Kohyama, Fumito Koike, Johannes Kollmann, Benjamin Komac, Kimberly Komatsu, Christian König, Nathan J. B. Kraft, Koen Kramer, Holger Kreft, Ingolf KĂŒhn, Dushan Kumarathunge, Jonas Kuppler, Hiroko Kurokawa, Yoko Kurosawa, Shem Kuyah, Jean-Paul Laclau, Benoit Lafleur, Erik Lallai, Eric Lamb, Andrea Lamprecht, Daniel J. Larkin, Daniel Laughlin, Yoann Le Bagousse-Pinguet, Guerric le Maire, Peter C. le Roux, Elizabeth le Roux, Tali Lee, Frederic Lens, Simon L. Lewis, Barbara Lhotsky, Yuanzhi Li, Xine Li, Jeremy W. Lichstein, Mario Liebergesell, Jun Ying Lim, Yan-Shih Lin, Juan Carlos Linares, Chunjiang Liu, Daijun Liu, Udayangani Liu, Stuart Livingstone, Joan LlusiĂ , Madelon Lohbeck, Ălvaro LĂłpez-GarcĂa, Gabriela Lopez-Gonzalez, ZdeĆka LososovĂĄ, FrĂ©dĂ©rique Louault, BalĂĄzs A. LukĂĄcs, Petr LukeĆĄ, Yunjian Luo, Michele Lussu, Siyan Ma, Camilla Maciel Rabelo Pereira, Michelle Mack, Vincent Maire, Annikki MĂ€kelĂ€, Harri MĂ€kinen, Ana Claudia Mendes Malhado, Azim Mallik, Peter Manning, Stefano Manzoni, Zuleica Marchetti, Luca Marchino, Vinicius Marcilio-Silva, Eric Marcon, Michela Marignani, Lars Markesteijn, Adam Martin, Cristina MartĂnez-Garza, Jordi MartĂnez-Vilalta, Tereza MaĆĄkovĂĄ, Kelly Mason, Norman Mason, Tara Joy Massad, Jacynthe Masse, Itay Mayrose, James McCarthy, M. Luke McCormack, Katherine McCulloh, Ian R. McFadden, Brian J. McGill, Mara Y. McPartland, Juliana S. Medeiros, Belinda Medlyn, Pierre Meerts, Zia Mehrabi, Patrick Meir, Felipe P. L. Melo, Maurizio Mencuccini, CĂ©line Meredieu, Julie Messier, Ilona MĂ©szĂĄros, Juha Metsaranta, Sean T. Michaletz, Chrysanthi Michelaki, Svetlana Migalina, Ruben Milla, Jesse E. D. Miller, Vanessa Minden, Ray Ming, Karel Mokany, Angela T. Moles, Attila MolnĂĄr V, Jane Molofsky, Martin Molz, Rebecca A. Montgomery, Arnaud Monty, Lenka MoravcovĂĄ, Alvaro Moreno-MartĂnez, Marco Moretti, Akira S. Mori, Shigeta Mori, Dave Morris, Jane Morrison, Ladislav Mucina, Sandra Mueller, Christopher D. Muir, Sandra Cristina MĂŒller, François Munoz, Isla H. Myers-Smith, Randall W. Myster, Masahiro Nagano, Shawna Naidu, Ayyappan Narayanan, Balachandran Natesan, Luka Negoita, Andrew S. Nelson, Eike Lena Neuschulz, Jian Ni, Georg Niedrist, Jhon Nieto, Ălo Niinemets, Rachael Nolan, Henning Nottebrock, Yann Nouvellon, Alexander Novakovskiy, The Nutrient Network, Kristin Odden Nystuen, Anthony O'Grady, Kevin O'Hara, Andrew O'Reilly-Nugent, Simon Oakley, Walter Oberhuber, Toshiyuki Ohtsuka, Ricardo Oliveira, Kinga Ăllerer, Mark E. Olson, Vladimir Onipchenko, Yusuke Onoda, Renske E. Onstein, Jenny C. Ordonez, Noriyuki Osada, Ivika Ostonen, Gianluigi Ottaviani, Sarah Otto, Gerhard E. Overbeck, Wim A. Ozinga, Anna T. Pahl, C. E. Timothy Paine, Robin J. Pakeman, Aristotelis C. Papageorgiou, Evgeniya Parfionova, Meelis PĂ€rtel, Marco Patacca, Susana Paula, Juraj Paule, Harald Pauli, Juli G. Pausas, Begoña Peco, Josep Penuelas, Antonio Perea, Pablo Luis Peri, Ana Carolina Petisco-Souza, Alessandro Petraglia, Any Mary Petritan, Oliver L. Phillips, Simon Pierce, ValĂ©rio D. Pillar, Jan Pisek, Alexandr Pomogaybin, Hendrik Poorter, Angelika Portsmuth, Peter Poschlod, Catherine Potvin, Devon Pounds, A. Shafer Powell, Sally A. Power, Andreas Prinzing, Giacomo Puglielli, Petr PyĆĄek, Valerie Raevel, Anja Rammig, Johannes Ransijn, Courtenay A. Ray, Peter B. Reich, Markus Reichstein, Douglas E. B. Reid, Maxime RĂ©jou-MĂ©chain, Victor Resco de Dios, Sabina Ribeiro, Sarah Richardson, Kersti Riibak, Matthias C. Rillig, Fiamma Riviera, Elisabeth M. R. Robert, Scott Roberts, Bjorn Robroek, Adam Roddy, Arthur Vinicius Rodrigues, Alistair Rogers, Emily Rollinson, Victor Rolo, Christine Römermann, Dina Ronzhina, Christiane Roscher, Julieta A. Rosell, Milena Fermina Rosenfield, Christian Rossi, David B. Roy, Samuel Royer-Tardif, Nadja RĂŒger, Ricardo Ruiz-Peinado, Sabine B. Rumpf, Graciela M. Rusch, Masahiro Ryo, Lawren Sack, Angela Saldaña, Beatriz Salgado-Negret, Roberto Salguero-Gomez, Ignacio Santa-Regina, Ana Carolina Santacruz-GarcĂa, Joaquim Santos, Jordi Sardans, Brandon Schamp, Michael Scherer-Lorenzen, Matthias Schleuning, Bernhard Schmid, Marco Schmidt, Sylvain Schmitt, Julio V. Schneider, Simon D. Schowanek, Julian Schrader, Franziska Schrodt, Bernhard Schuldt, Frank Schurr, Galia Selaya Garvizu, Marina Semchenko, Colleen Seymour, Julia C. Sfair, Joanne M. Sharpe, Christine S. Sheppard, Serge Sheremetiev, Satomi Shiodera, Bill Shipley, Tanvir Ahmed Shovon, Alrun SiebenkĂ€s, Carlos Sierra, Vasco Silva, Mateus Silva, Tommaso Sitzia, Henrik Sjöman, Martijn Slot, Nicholas G. Smith, Darwin Sodhi, Pamela Soltis, Douglas Soltis, Ben Somers, GrĂ©gory Sonnier, Mia Vedel SĂžrensen, Enio Egon Sosinski Jr, Nadejda A. Soudzilovskaia, Alexandre F. Souza, Marko Spasojevic, Marta Gaia Sperandii, Amanda B. Stan, James Stegen, Klaus Steinbauer, Jörg G. Stephan, Frank Sterck, Dejan B. Stojanovic, Tanya Strydom, Maria Laura Suarez, Jens-Christian Svenning, Ivana SvitkovĂĄ, Marek Svitok, Miroslav Svoboda, Emily Swaine, Nathan Swenson, Marcelo Tabarelli, Kentaro Takagi, Ulrike Tappeiner, RubĂ©n Tarifa, Simon Tauugourdeau, Cagatay Tavsanoglu, Mariska te Beest, Leho Tedersoo, Nelson Thiffault, Dominik Thom, Evert Thomas, Ken Thompson, Peter E. Thornton, Wilfried Thuiller, LubomĂr TichĂœ, David Tissue, Mark G. Tjoelker, David Yue Phin Tng, Joseph Tobias, PĂ©ter Török, Tonantzin Tarin, JosĂ© M. Torres-Ruiz, BĂ©la TĂłthmĂ©rĂ©sz, Martina Treurnicht, Valeria Trivellone, Franck Trolliet, Volodymyr Trotsiuk, James L. Tsakalos, Ioannis Tsiripidis, Niklas Tysklind, Toru Umehara, Vladimir Usoltsev, Matthew Vadeboncoeur, Jamil Vaezi, Fernando Valladares, Jana Vamosi, Peter M. van Bodegom, Michiel van Breugel, Elisa Van Cleemput, Martine van de Weg, Stephni van der Merwe, Fons van der Plas, Masha T. van der Sande, Mark van Kleunen, Koenraad Van Meerbeek, Mark Vanderwel, Kim AndrĂ© Vanselow, Angelica VĂ„rhammar, Laura Varone, Maribel Yesenia Vasquez Valderrama, Kiril Vassilev, Mark Vellend, Erik J. Veneklaas, Hans Verbeeck, Kris Verheyen, Alexander Vibrans, Ima Vieira, Jaime VillacĂs, Cyrille Violle, Pandi Vivek, Katrin Wagner, Matthew Waldram, Anthony Waldron, Anthony P. Walker, Martyn Waller, Gabriel Walther, Han Wang, Feng Wang, Weiqi Wang, Harry Watkins, James Watkins, Ulrich Weber, James T. Weedon, Liping Wei, Patrick Weigelt, Evan Weiher, Aidan W. Wells, Camilla Wellstein, Elizabeth Wenk, Mark Westoby, Alana Westwood, Philip John White, Mark Whitten, Mathew Williams, Daniel E. Winkler, Klaus Winter, Chevonne Womack, Ian J. Wright, S. Joseph Wright, Justin Wright, Bruno X. Pinho, Fabiano Ximenes, Toshihiro Yamada, Keiko Yamaji, Ruth Yanai, Nikolay Yankov, Benjamin Yguel, KĂĄtia Janaina Zanini, Amy E. Zanne, David ZelenĂœ, Yun-Peng Zhao, Jingming Zheng, Ji Zheng, Kasia ZiemiĆska, Chad R. Zirbel, Georg Zizka, IriĂ© Casimir Zo-Bi, Gerhard Zotz, Christian Wirth.Max Planck Institute for Biogeochemistry;
Max Planck Society;
German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig;
International Programme of Biodiversity Science (DIVERSITAS);
International Geosphere-Biosphere Programme (IGBP);
Future Earth;
French Foundation for Biodiversity Research (FRB);
GIS âClimat, Environnement et SociĂ©tĂ©'.http://wileyonlinelibrary.com/journal/gcbhj2021Plant Production and Soil Scienc
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