101 research outputs found

    Multi-View Priors for Learning Detectors from Sparse Viewpoint Data

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    While the majority of today's object class models provide only 2D bounding boxes, far richer output hypotheses are desirable including viewpoint, fine-grained category, and 3D geometry estimate. However, models trained to provide richer output require larger amounts of training data, preferably well covering the relevant aspects such as viewpoint and fine-grained categories. In this paper, we address this issue from the perspective of transfer learning, and design an object class model that explicitly leverages correlations between visual features. Specifically, our model represents prior distributions over permissible multi-view detectors in a parametric way -- the priors are learned once from training data of a source object class, and can later be used to facilitate the learning of a detector for a target class. As we show in our experiments, this transfer is not only beneficial for detectors based on basic-level category representations, but also enables the robust learning of detectors that represent classes at finer levels of granularity, where training data is typically even scarcer and more unbalanced. As a result, we report largely improved performance in simultaneous 2D object localization and viewpoint estimation on a recent dataset of challenging street scenes.Comment: 13 pages, 7 figures, 4 tables, International Conference on Learning Representations 201

    3D Object Class Detection in the Wild

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    Object class detection has been a synonym for 2D bounding box localization for the longest time, fueled by the success of powerful statistical learning techniques, combined with robust image representations. Only recently, there has been a growing interest in revisiting the promise of computer vision from the early days: to precisely delineate the contents of a visual scene, object by object, in 3D. In this paper, we draw from recent advances in object detection and 2D-3D object lifting in order to design an object class detector that is particularly tailored towards 3D object class detection. Our 3D object class detection method consists of several stages gradually enriching the object detection output with object viewpoint, keypoints and 3D shape estimates. Following careful design, in each stage it constantly improves the performance and achieves state-ofthe-art performance in simultaneous 2D bounding box and viewpoint estimation on the challenging Pascal3D+ dataset

    Europäische Integration aus historischer Erfahrung. Ein Zeitzeugengespräch mit Michael Gehler = European integration from historical experience. An eyewitness conversation with Michael Gehler. ZEI Discussion Paper C 251 / 2019

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    Günther H. Oettinger, born in 1953 in Stuttgart, served as Prime Minister of the state of Baden-Wuerttemberg from 2005 to 2010. He was European Commissioner for Energy (2010-2014) in the Barroso-Commission II. and in 2014 he also was Vice-President of the European Commission. In the Juncker-Commission, he served as Commissioner for Digital Economy and Society from 2014 to 2017 and in 2017 he became Commissioner for Budget & Human Resources - a particular high challenge in the light of the Brexit-debate. In this eyewitness dialogue, he talks about his family background, his professional career and political party affiliation, the Barroso Commission II, his functions as Energy Commissioner and his experience with the difficult common European energy policy. His greatest political success was resolving the gas dispute between Russia and Ukraine in September 2014. This very informative paper also deals with issues concerning the development and priorities of the European Commission and with the future of the European Union

    [68Ga]-DOTATOC-PET/CT for meningioma IMRT treatment planning

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    <p>Abstract</p> <p>Purpose</p> <p>The observation that human meningioma cells strongly express somatostatin receptor (SSTR 2) was the rationale to analyze retrospectively in how far DOTATOC PET/CT is helpful to improve target volume delineation for intensity modulated radiotherapy (IMRT).</p> <p>Patients and Methods</p> <p>In 26 consecutive patients with preferentially skull base meningioma, diagnostic magnetic resonance imaging (MRI) and planning-computed tomography (CT) was complemented with data from [<sup>68</sup>Ga]-DOTA-D Phe<sup>1</sup>-Tyr<sup>3</sup>-Octreotide (DOTATOC)-PET/CT. Image fusion of PET/CT, diagnostic computed tomography, MRI and radiotherapy planning CT as well as target volume delineation was performed with OTP-Masterplan<sup>®</sup>. Initial gross tumor volume (GTV) definition was based on MRI data only and was secondarily complemented with DOTATOC-PET information. Irradiation was performed as EUD based IMRT, using the Hyperion Software package.</p> <p>Results</p> <p>The integration of the DOTATOC data led to additional information concerning tumor extension in 17 of 26 patients (65%). There were major changes of the clinical target volume (CTV) which modify the PTV in 14 patients, minor changes were realized in 3 patients. Overall the GTV-MRI/CT was larger than the GTV-PET in 10 patients (38%), smaller in 13 patients (50%) and almost the same in 3 patients (12%). Most of the adaptations were performed in close vicinity to bony skull base structures or after complex surgery. Median GTV based on MRI was 18.1 cc, based on PET 25.3 cc and subsequently the CTV was 37.4 cc. Radiation planning and treatment of the DOTATOC-adapted volumes was feasible.</p> <p>Conclusion</p> <p>DOTATOC-PET/CT information may strongly complement patho-anatomical data from MRI and CT in cases with complex meningioma and is thus helpful for improved target volume delineation especially for skull base manifestations and recurrent disease after surgery.</p

    Design of a dual species atom interferometer for space

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    Atom interferometers have a multitude of proposed applications in space including precise measurements of the Earth's gravitational field, in navigation & ranging, and in fundamental physics such as tests of the weak equivalence principle (WEP) and gravitational wave detection. While atom interferometers are realized routinely in ground-based laboratories, current efforts aim at the development of a space compatible design optimized with respect to dimensions, weight, power consumption, mechanical robustness and radiation hardness. In this paper, we present a design of a high-sensitivity differential dual species 85^{85}Rb/87^{87}Rb atom interferometer for space, including physics package, laser system, electronics and software. The physics package comprises the atom source consisting of dispensers and a 2D magneto-optical trap (MOT), the science chamber with a 3D-MOT, a magnetic trap based on an atom chip and an optical dipole trap (ODT) used for Bose-Einstein condensate (BEC) creation and interferometry, the detection unit, the vacuum system for 10−1110^{-11} mbar ultra-high vacuum generation, and the high-suppression factor magnetic shielding as well as the thermal control system. The laser system is based on a hybrid approach using fiber-based telecom components and high-power laser diode technology and includes all laser sources for 2D-MOT, 3D-MOT, ODT, interferometry and detection. Manipulation and switching of the laser beams is carried out on an optical bench using Zerodur bonding technology. The instrument consists of 9 units with an overall mass of 221 kg, an average power consumption of 608 W (819 W peak), and a volume of 470 liters which would well fit on a satellite to be launched with a Soyuz rocket, as system studies have shown.Comment: 30 pages, 23 figures, accepted for publication in Experimental Astronom

    Transcriptional Responses of Cultured Rat Sympathetic Neurons during BMP-7-Induced Dendritic Growth

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    Dendrites are the primary site of synapse formation in the vertebrate nervous system; however, relatively little is known about the molecular mechanisms that regulate the initial formation of primary dendrites. Embryonic rat sympathetic neurons cultured under defined conditions extend a single functional axon, but fail to form dendrites. Addition of bone morphogenetic proteins (BMPs) triggers these neurons to extend multiple dendrites without altering axonal growth or cell survival. We used this culture system to examine differential gene expression patterns in naïve vs. BMP-treated sympathetic neurons in order to identify candidate genes involved in regulation of primary dendritogenesis.To determine the critical transcriptional window during BMP-induced dendritic growth, morphometric analysis of microtubule-associated protein (MAP-2)-immunopositive processes was used to quantify dendritic growth in cultures exposed to the transcription inhibitor actinomycin-D added at varying times after addition of BMP-7. BMP-7-induced dendritic growth was blocked when transcription was inhibited within the first 24 hr after adding exogenous BMP-7. Thus, total RNA was isolated from sympathetic neurons exposed to three different experimental conditions: (1) no BMP-7 treatment; (2) treatment with BMP-7 for 6 hr; and (3) treatment with BMP-7 for 24 hr. Affymetrix oligonucleotide microarrays were used to identify differential gene expression under these three culture conditions. BMP-7 significantly regulated 56 unique genes at 6 hr and 185 unique genes at 24 hr. Bioinformatic analyses implicate both established and novel genes and signaling pathways in primary dendritogenesis.This study provides a unique dataset that will be useful in generating testable hypotheses regarding transcriptional control of the initial stages of dendritic growth. Since BMPs selectively promote dendritic growth in central neurons as well, these findings may be generally applicable to dendritic growth in other neuronal cell types
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