A COMPARATIVE STUDY ON THE EFFECT OF LIQUOR RATIO OF ACID AND NEUTRAL(POWDER) ENZYME ON DENIM GARMENTS

Young people as well as older people have now great passion for the denim cloth. Today jeans are available in many colors and designs. In this study we tried to reveal the difference in between two types of cellulase enzymes acid and neutral (powder) enzyme. To do this, denim samples were collected and prepared according to the recipe of equal amount of enzyme by varying the liquor ratio. Basically there were no differences found in between acid and powder enzyme on different fastness properties like rubbing, washing, perspiration, light fastness test. But there was a significant difference in weight loss%. Acid enzyme exhibited little bit more enzymatic effect than powder enzyme and it also showed more weight loss % . But the neutral enzyme required less money rather than acid enzyme and no need to control pH, easy to use. Moreover, lower liquor ratio gave higher abrasion. Acid enzyme gave more back staining than neutral enzyme

Application of New Synthetic Fifth Generation Thickeners for Printing Cotton Fabric with Reactive Dyes

In this study,  fifth generation thickener EM620R (polyacrylate emulsion) was developed for reactive printing due to traditional thickener sodium alginate and synthetic thickener caused less saturation of color and increased fabric stiffness.  Printing was evaluated for the depth of the shade as well as other properties. The properties was obtained not only depending on the thickener and reactive dye but also depends on the concentration of NaHCO3, Urea in Printing paste, condition of fixation and storing time.  After comparison with synthetic thickener and sodium alginate on the basis of K/S  value in different situation, AATCC method fastness test; an extra ordinary  result came out which was shown as like EM620R (polyacrylate emulsion) EM620 (polyacrylate emulsion) Sodium Alginate. Although EM620R (polyacrylate emulsion) development solved the problem and increased the properties which create unthinkable impact on the world market for cost effectiveness

The impact of viral mutations on recognition by SARS-CoV-2 specific T cells.

We identify amino acid variants within dominant SARS-CoV-2 T cell epitopes by interrogating global sequence data. Several variants within nucleocapsid and ORF3a epitopes have arisen independently in multiple lineages and result in loss of recognition by epitope-specific T cells assessed by IFN-γ and cytotoxic killing assays. Complete loss of T cell responsiveness was seen due to Q213K in the A∗01:01-restricted CD8+ ORF3a epitope FTSDYYQLY207-215; due to P13L, P13S, and P13T in the B∗27:05-restricted CD8+ nucleocapsid epitope QRNAPRITF9-17; and due to T362I and P365S in the A∗03:01/A∗11:01-restricted CD8+ nucleocapsid epitope KTFPPTEPK361-369. CD8+ T cell lines unable to recognize variant epitopes have diverse T cell receptor repertoires. These data demonstrate the potential for T cell evasion and highlight the need for ongoing surveillance for variants capable of escaping T cell as well as humoral immunity.This work is supported by the UK Medical Research Council (MRC); Chinese Academy of Medical Sciences(CAMS) Innovation Fund for Medical Sciences (CIFMS), China; National Institute for Health Research (NIHR)Oxford Biomedical Research Centre, and UK Researchand Innovation (UKRI)/NIHR through the UK Coro-navirus Immunology Consortium (UK-CIC). Sequencing of SARS-CoV-2 samples and collation of data wasundertaken by the COG-UK CONSORTIUM. COG-UK is supported by funding from the Medical ResearchCouncil (MRC) part of UK Research & Innovation (UKRI),the National Institute of Health Research (NIHR),and Genome Research Limited, operating as the Wellcome Sanger Institute. T.I.d.S. is supported by a Well-come Trust Intermediate Clinical Fellowship (110058/Z/15/Z). L.T. is supported by the Wellcome Trust(grant number 205228/Z/16/Z) and by theUniversity of Liverpool Centre for Excellence in Infectious DiseaseResearch (CEIDR). S.D. is funded by an NIHR GlobalResearch Professorship (NIHR300791). L.T. and S.C.M.are also supported by the U.S. Food and Drug Administration Medical Countermeasures Initiative contract75F40120C00085 and the National Institute for Health Research Health Protection Research Unit (HPRU) inEmerging and Zoonotic Infections (NIHR200907) at University of Liverpool inpartnership with Public HealthEngland (PHE), in collaboration with Liverpool School of Tropical Medicine and the University of Oxford.L.T. is based at the University of Liverpool. M.D.P. is funded by the NIHR Sheffield Biomedical ResearchCentre (BRC – IS-BRC-1215-20017). ISARIC4C is supported by the MRC (grant no MC_PC_19059). J.C.K.is a Wellcome Investigator (WT204969/Z/16/Z) and supported by NIHR Oxford Biomedical Research Centreand CIFMS. The views expressed are those of the authors and not necessarily those of the NIHR or MRC

Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission

Understanding SARS-CoV-2 transmission in higher education settings is important to limit spread between students, and into at-risk populations. In this study, we sequenced 482 SARS-CoV-2 isolates from the University of Cambridge from 5 October to 6 December 2020. We perform a detailed phylogenetic comparison with 972 isolates from the surrounding community, complemented with epidemiological and contact tracing data, to determine transmission dynamics. We observe limited viral introductions into the university; the majority of student cases were linked to a single genetic cluster, likely following social gatherings at a venue outside the university. We identify considerable onward transmission associated with student accommodation and courses; this was effectively contained using local infection control measures and following a national lockdown. Transmission clusters were largely segregated within the university or the community. Our study highlights key determinants of SARS-CoV-2 transmission and effective interventions in a higher education setting that will inform public health policy during pandemics