Ten Broeck Cottage for Sears Company/Willis Group Holding in Columbia County, New York

Material of interest: Metal. Material used: Corten steel. Material properties: Corten Steel was used for the exterior cladding of this structure. This type of metal is created due to natural rusting. It allows for the building facade to age naturally without regular maintenance.https://openscholarship.wustl.edu/bcs/1125/thumbnail.jp

The sphaeromatid genus Paracilicaea Stebbing 1910 (Crustacea Isopoda) from the Western Indian Ocean with the description of five new species

Seven species of Paracilicaea are recorded from intertidal habitats on the coasts of Somalia and the Yemen, Western Indian Ocean. Paracilicaea falcata n. sp., P. mirabilis n. sp., P. nodosa n. sp., P. peniculata n. sp. and P. uncinata n. sp. are described. The genus Paracilicaea Stebbing 1910 from the Indo-Pacific region is revised and redefined. Four species are excluded from Paracilicaea and are here regarded as "incertae sedis": P. dakini (Tattersall 1922), P. fimbriata Kussakin et al. 1990, P. hamata (Baker 1908) and P. septemdentata (Baker 1910). A key to the species of the genus is given, together with a synoptic list of all species, with their synonymy and distribution

Pongycarcinia xiphidiourus n. gen. n. sp.,a new Brazilian Calabozoidae (Crustacea Isopoda)

The discovery of a second species of Calabozoidae, in a cave of an ancient karstic zone of the Bahia State (Brazil), provides new insights into the suborder Calabozoidea, described by VAN LIESHOUT in 1983 and represented until now by a single species Calabozoa pellucida Van Lieshout 1983 inhabiting the subterranean waters of Venezuela. The new finding expands the distribution range of the suborder and permits further studies to clarify its uncertain phylogeny. It also demonstrates a greater diversity of the isopod taxa in Brazilian subterranean waters than previously known. This suggests that a more detailed search would increase the chances of finding further interesting specimens of Crustacea in this region. The belonging of the newly discovered specimens to a new genus and species Pongycarcinia xiphidiourus is justified by the presence of peculiar characters, such as the shape of the second male pleopod and of some structures of the stomach. The two theories of the phylogeny of this isopod taxon, one linking it to the suborder Asellota through common ancestors, the other considering it more closely related to Oniscoidea, are discussed. KEY WORDS: stygofauna, Calabozoidea, Brazil, new genus, new species

Prevention of Peritonitis in Peritoneal Dialysis

Reducing the frequency of peritonitis for patients undergoing peritoneal dialysis ( PD ) continues to be a challenge. This review focuses on recent updates in catheter care and other patient factors that influence infection rates. An experienced nursing staff plays an important role in teaching proper PD technique to new patients, but nursing staff must be cognizant of each patient's unique educational needs. Over time, many patients become less adherent to proper dialysis technique, such as washing hands or wearing a mask. This behavior is associated with higher risk of peritonitis and is modifiable with re‐training. Prophylactic antibiotics before PD catheter placement can decrease the infection risk immediately after catheter placement. In addition, some studies suggest that prophylaxis against fungal superinfection after antibiotic exposure is effective in reducing fungal peritonitis, although larger randomized studies are needed before this practice can be recommended for all patients. Over time, exit site and nasal colonization with pathogenic organisms can lead to exit‐site infections and peritonitis. For patients with S taphylococcus aureus colonization, exit‐site prophylaxis with either mupirocin or gentamicin cream reduces clinical infection with this organism. Although there are limited data for support, antibiotic prophylaxis before gastrointestinal, gynecologic, or dental procedures may also help reduce the risk of peritonitis.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/99100/1/sdi12114.pd

NAMPT and NAPRT: Two Metabolic Enzymes With Key Roles in Inflammation

Nicotinamide phosphoribosyltransferase (NAMPT) and nicotinate phosphoribosyltransferase (NAPRT) are two intracellular enzymes that catalyze the first step in the biosynthesis of NAD from nicotinamide and nicotinic acid, respectively. By fine tuning intracellular NAD levels, they are involved in the regulation/reprogramming of cellular metabolism and in the control of the activity of NAD-dependent enzymes, including sirtuins, PARPs, and NADases. However, during evolution they both acquired novel functions as extracellular endogenous mediators of inflammation. It is well-known that cellular stress and/or damage induce release in the extracellular milieu of endogenous molecules, called alarmins or damage-associated molecular patterns (DAMPs), which modulate immune functions through binding pattern recognition receptors (PRRs), such as Toll-like receptors (TLRs), and activate inflammatory responses. Increasing evidence suggests that extracellular (e)NAMPT and eNAPRT are novel soluble factors with cytokine/adipokine/DAMP-like actions. Elevated eNAMPT were reported in several metabolic and inflammatory disorders, including obesity, diabetes, and cancer, while eNAPRT is emerging as a biomarker of sepsis and septic shock. This review will discuss available data concerning the dual role of this unique family of enzymes