Physical Education Teachers\u27 Experiences With Remote Instruction During The Initial Phase Of The Covid-19 Pandemic

This study investigated physical education (PE) teachers\u27 experiences with remote instruction in the United States during the initial outbreak of COVID-19. PE teachers (n = 4,362) from all 50 states completed a survey identifying their experiences with remote instruction in May, 2020. Survey responses were analyzed by geographic region, district type, and school level. Teachers reported having students submit assignments (51% yes), using video instruction (37% yes), being less effective when instructing remotely (20% yes), and emphasizing student outcomes focused on health-related fitness (32% yes), and physical activity value/ enjoyment (43% yes). Access to technology (40% yes) and required student assignments (43% yes) were lowest among teachers from the South. Rural teachers reported the least access to technology (37% yes) and rated themselves as least effective (24% yes). Secondary level teachers reported the highest percentage of required assignments (84% yes). Teachers\u27 responses identify unique challenges to delivering equitable and effective remote PE instruction

Elongation factor Tu's nucleotide binding is governed by a thermodynamic landscape unique among bacterial translation factors.

Molecular switches such as GTPases are powerful devices turning "on" or "off" biomolecular processes at the core of critical biological pathways. To develop molecular switches de novo, an intimate understanding of how they function is required. Here we investigate the thermodynamic parameters that define the nucleotide-dependent switch mechanism of elongation factor (EF) Tu as a prototypical molecular switch. EF-Tu alternates between GTP- and GDP-bound conformations during its functional cycle, representing the "on" and "off' states, respectively. We report for the first time that the activation barriers for nucleotide association are the same for both nucleotides, suggesting a guanosine nucleoside or ribose-first mechanism for nucleotide association. Additionally, molecular dynamics (MD) simulations indicate that enthalpic stabilization of GDP binding compared to GTP binding originates in the backbone hydrogen bonding network of EF-Tu. In contrast, binding of GTP to EF-Tu is entropically driven by the liberation of bound water during the GDP- to GTP-bound transition. GDP binding to the apo conformation of EF-Tu is both enthalpically and entropically favored, a feature unique among translational GTPases. This indicates that the apo conformation does not resemble the GDP-bound state. Finally, we show that antibiotics and single amino acid substitutions can be used to target specific structural elements in EF-Tu to redesign the thermodynamic landscape. These findings demonstrate how, through evolution, EF-Tu has fine-tuned the structural and dynamic features that define nucleotide binding, providing insight into how altering these properties could be exploited for protein engineering

The effects of room design on computer-supported collaborative learning in a multi-touch classroom.

While research indicates that technology can be useful for supporting learning and collaboration, there is still relatively little uptake or widespread implementation of these technologies in classrooms. In this paper, we explore one aspect of the development of a multi-touch classroom, looking at two different designs of the classroom environment to explore how classroom layout may influence group interaction and learning. Three classes of students working in groups of four were taught in the traditional forward-facing room condition, while three classes worked in a centered room condition. Our results indicate that while the outcomes on tasks were similar across conditions, groups engaged in more talk (but not more off-task talk) in a centered room layout, than in a traditional forward-facing room. These results suggest that the use of technology in the classroom may be influenced by the location of the technology, both in terms of the learning outcomes and the interaction behaviors of students. The findings highlight the importance of considering the learning environment when designing technology to support learning, and ensuring that integration of technology into formal learning environments is done with attention to how the technology may disrupt, or contribute to, the classroom interaction practices

The Production of Epistemic Culture and Agency during a First-Grade Engineering Design Unit in an Urban Emergent School

Primary school practices are often bound by traditions that perpetuate compliance and skills-based, decontextualized, rote memorization activities. These histories of practice, prevalent in schools serving mostly Black and Brown children, make it inordinately difficult for students to author themselves as knowledge builders (i.e., with epistemic agency), which is a form of injustice. Engineering is a potentially fertile context to support the creation of epistemic culture, whereby young students’ assets are recognized, named, and leveraged as they create and shape the group’s disciplinary knowledge. The authors investigated this potential. The primary research question was: How do first-grade students in an urban emergent school author themselves as epistemic agents during an engineering design unit? Using a social practice theory lens and ethnographic methods, the authors studied 29 days of a materials engineering unit focusing on the teacher’s epistemic commitments, implicit meanings of knowledge in classroom discourse, and practices that opened space for students’ epistemic agency. Data collection included fieldnotes and video of class activities and teacher and student interviews. Class discussions about the properties and uses of materials yielded a rich context for studying epistemic culture. The teacher’s epistemic commitments included an eschewing of disciplinary silos, recognizing the nonlinear nature of knowledge-building about engineering, and acknowledging children’s thinking as an asset for engineering knowledge production. Examples of students’ discursive moves demonstrating epistemic agency included: reminding others about the relevance of previous lessons to the current topic, mirroring the teacher’s instructional moves, claiming voice, space, time, and material resources for knowledge-building, translating one another’s ideas, and making unsolicited connections to their lives. Young children’s intellectual assets can too easily be overlooked in traditional learning contexts. This study demonstrates the affordances of responsive engineering instruction in recognizing and building on youths’ intellectual curiosity and enthusiasm for substantively contributing to the classroom’s knowledge-generating practices

Real time plasma equilibrium reconstruction in a Tokamak

The problem of equilibrium of a plasma in a Tokamak is a free boundary problemdescribed by the Grad-Shafranov equation in axisymmetric configurations. The right hand side of this equation is a non linear source, which represents the toroidal component of the plasma current density. This paper deals with the real time identification of this non linear source from experimental measurements. The proposed method is based on a fixed point algorithm, a finite element resolution, a reduced basis method and a least-square optimization formulation

Maternal and postnatal overnutrition differentially impact appetite regulators and fuel metabolism

Maternal obesity is increasing, and it is known that the intrauterine experience programs fetal and newborn metabolism. However, the relative contributions of pre- or postnatal factors are unknown. We hypothesized that maternal overnutrition caused by long-term maternal obesity would exert a stronger detrimental impact than postnatal overnutrition on offspring metabolic homeostasis, with additional postnatal overnutrition exaggerating these alterations. Female Sprague Dawley rats were exposed to chow or high-fat cafeteria diet for 5 wk before mating and throughout gestation and lactation. On postnatal d 1, litters were adjusted to three per litter to induce postnatal overnutrition (vs. 12 in control). Hypothalamic appetite regulators neuropeptide Y and proopiomelanocortin, glucose transporter 4, and lipid metabolic markers were measured. At postnatal d 20, male pups born of obese dams, or those overnourished postnatally, were 42% heavier than controls; combining both interventions led to 80% greater body weight. Maternal obesity increased pup adiposity and led to glucose intolerance in offspring; these were exaggerated by additional postnatal overnutrition during lactation. Maternal obesity was also linked to hyperlipidemia in offspring and reduced hypothalamic neuropeptide Y and increased proopiomelanocortin mRNA expression. Postnatal overnutrition of offspring from obese dams amplified these hypothalamic changes. Both maternal and postnatal overnutrition reduced muscle glucose transporter 4. Adipose carnitine palmitoyl-transferase-1 and adipose triglyceride lipase mRNA was up-regulated only by postnatal overnutrition. Maternal overnutrition appears to alter central appetite circuits and promotes early-onset obesity; postnatal overnutrition interacted to cause peripheral lipid and glucose metabolic disorders, supporting the critical message to reduce early-life adverse nutritional impact. Copyright © 2008 by The Endocrine Society

Juvenile vervet monkeys rely on others when responding to danger

Funding: Open access funding provided by University of Lausanne. Funding was provided by FP7 Ideas: European Research Council, 283871, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, 310030_143359, PP00P3_170624, Branco Weiss Fellowship-Society in Science.Primate alarm calls are mainly hardwired but individuals need to adapt their calling behaviours according to the situation. Such learning necessitates recognising locally relevant dangers and may take place via their own experience or by observing others. To investigate monkeys alarm calling behaviour, we carried out a field experiment in which we exposed juvenile vervet monkeys to unfamiliar raptor models in the presence of audiences that differed in experience and reliability. We used audience age as a proxy for experience and relatedness as a proxy for reliability, while quantifying audience reactions to the models. We found a negative correlation between alarm call production and callers’ age. Adults never alarm called, compared to juveniles. We found no overall effect of audience composition and size, with juveniles calling more when with siblings than mothers or unrelated individuals. Finally, concerning audience reactions to the models, we observed juveniles remained silent with vigilant mothers and only alarm called with ignoring mothers, whereas we observed the opposite for siblings: juveniles remained silent with ignoring siblings and called with vigilant siblings. Despite the small sample size, juvenile vervet monkeys, confronted with unfamiliar and potentially dangerous raptors, seem to rely on others to decide whether to alarm call, demonstrating that the choice of the model may play an important key role in the ontogeny of primate alarm call behaviour.Publisher PDFPeer reviewe

Validation of surface velocity estimated from satellite images

This report concerns the validation of surface velocity estimated from satellite images. The estimation is obtained with a dynamic model based on shallow-water equations. We first compare the stationary assumption to the shallow-water heuristics to justify our choice. Second, we quantify the quality of the estimation by measuring the misfit between the model output and the altimetry measures. Experiments are achieved on Sea Surface Temperature data acquired by the NOAA/AVHRR satellites over the Black Sea. The altimetry measures are obtained by two radar sensors: Envisat and GFO. The good adequacy between the shallow-water output and the altimetry data validates our motion estimation approach.Ce rapport de recherche concerne la validation de l'estimation de la vitesse de surface à partir d'images satellite. Cette estimation est effectuée avec un modèle de la dynamique, basé sur les équations shallow-water. Nous comparons d'abord l'hypothèse de stationnarité aux équations shallow-water afin de justifier notre choix. Puis, nous quantifions la qualité des estimations en mesurant l'écart entre la sortie du modèle et les mesures d'altimétrie. Les expérimentations sont effectuées en utilisant des données de température de surface, acquises au-dessus de la Mer Noire avec les satellites NOAA/AVHRR. Les mesures altimétriques proviennent de deux capteurs radar : Envisat et GFO. La bonne adéquation entre la sortie du modèle shallow-water et les données altimétriques valide notre approche d'estimation du mouvement

Measurement of the electron electric dipole moment using GdIG

A new method for the detection of the electron edm using a solid is described. The method involves the measurement of a voltage induced across the solid by the alignment of the samples magnetic dipoles in an applied magnetic field, H. A first application of the method to GdIG has resulted in a limit on the electron edm of 5E-24 e-cm, which is a factor of 40 below the limit obtained from the only previous solid-state edm experiment. The result is limited by the imperfect discrimination of an unexpectedly large voltage that is even upon the reversal of the sample magnetization.Comment: 10 pages, 5 figures, v2:references corrected, submitted to PRL, v3:added labels to figure