462 research outputs found

    EVALUATION OF SEMEN QUALITY IN RABBIT OF LOCAL ALGERIAN POPULATION AND SYNTHETIC LINE IN THE SUMMER SEASON: A COMPARATIVE STUDY

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    The aim of our study was to compare the libido and semen characteristics in 24 rabbits of local and synthetic line during summer season. Results showed that both breeds had similar (p ˃0.05) libido (13.92 vs 16.85 s). Gel free volume (0.88 vs. 0.87 mL), pH (7.51 vs. 7.65), and live sperm (56.21 vs. 55.88%) were similar. Local population had higher semen concentration (398.50 x106 /mL vs. 328.90 x106 /mL) and percentage of abnormal spermatozoa (36.54 vs 30.28%). Massal and individual motility (p=0.006 and p=0.008) were significantly increased in local population. Kinetic traits for Local population were significantly greater (P<0.05), except for VCL, ALH and BCF. We conclude that, rabbit bucks of local population had a good ability of adaptation to produce in a hot climate

    Spectrum of the Relativistic Particles in Various Potentials

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    We extend the notion of Dirac oscillator in two dimensions, to construct a set of potentials. These potentials becomes exactly and quasi-exactly solvable potentials of non-relativistic quantum mechanics when they are transformed into a Schr\"{o}dinger-like equation. For the exactly solvable potentials, eigenvalues are calculated and eigenfunctions are given by confluent hypergeometric functions. It is shown that, our formulation also leads to the study of those potentials in the framework of the supersymmetric quantum mechanics

    Building biosecurity for synthetic biology.

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    The fast-paced field of synthetic biology is fundamentally changing the global biosecurity framework. Current biosecurity regulations and strategies are based on previous governance paradigms for pathogen-oriented security, recombinant DNA research, and broader concerns related to genetically modified organisms (GMOs). Many scholarly discussions and biosecurity practitioners are therefore concerned that synthetic biology outpaces established biosafety and biosecurity measures to prevent deliberate and malicious or inadvertent and accidental misuse of synthetic biology's processes or products. This commentary proposes three strategies to improve biosecurity: Security must be treated as an investment in the future applicability of the technology; social scientists and policy makers should be engaged early in technology development and forecasting; and coordination among global stakeholders is necessary to ensure acceptable levels of risk

    Circulating senescent myeloid cells drive blood brain barrier breakdown and neurodegeneration

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    Neurodegenerative diseases (ND) are characterized by progressive loss of neuronal function. Mechanisms of ND pathogenesis are incompletely understood, hampering the development of effective therapies. Langerhans cell histiocytosis (LCH) is an inflammatory neoplastic disorder caused by hematopoietic progenitors expressing MAPK activating mutations that differentiate into senescent myeloid cells that drive lesion formation. Some patients with LCH subsequently develop progressive and incurable neurodegeneration (LCH-ND). Here, we show that LCH-ND is caused by myeloid cells that are clonal with peripheral LCH cells. We discovered that circulating BRAF V600E +^{+} myeloid cells cause the breakdown of the blood-brain barrier (BBB), enhancing migration into the brain parenchyma where they differentiate into senescent, inflammatory CD11a +^{+} macrophages that accumulate in the brainstem and cerebellum. Blocking MAPK activity and senescence programs reduced parenchymal infiltration, neuroinflammation, neuronal damage and improved neurological outcome in preclinical LCH-ND. MAPK activation and senescence programs in circulating myeloid cells represent novel and targetable mechanisms of ND

    Data Resource Profile: The Mental Health of Children and Young People Surveys (MHCYP).

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    This is the author accepted manuscript. The final version is available from Oxford University Press via the DOI in this record.England’s Department of Health and Social Car

    UNDERWATER PHOTOGRAMMETRY, CODED TARGET AND PLENOPTIC TECHNOLOGY: A SET OF TOOLS FOR MONITORING RED CORAL IN MEDITERRANEAN SEA IN THE FRAMEWORK OF THE ”PERFECT” PROJECT

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    PErfECT "Photogrammetry, gEnetic, Ecology for red coral ConservaTion" is a project leaded by the Laboratoire des Sciences de lInformation et des Systmes (LSIS - UMR 7296 CNRS) from the Aix-Marseille University (France) in collaboration with the Spanish National Agency for Scientific Research (CSIC, Spain). The main objective of the project is to develop innovative Tools for the conservation of the Mediterranean red coral, Corallium rubrum. PErfECT was funded by the Total Fundation. The adaptation of digital photogrammetric techniques for use in submarine is rapidly increasing in recent years. In fact, these techniques are particularly well suited for use in underwater environments. PErfECT developed different photogrammetry tools to enhance the red coral population surveys based in: (i) automatic orientation on coded quadrats, (ii) use of NPR (Non Photo realistic Rendering) techniques, (iii) the calculation of distances between colonies within local populations and finally (iv) the use of plenoptic approaches in underwater conditions

    Photogrammetric surveys and geometric processes to analyse and monitor red coral colonies

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    This article describes the set of photogrammetric tools developed for the monitoring of Mediterranean red coral Corallium rubrum populations. The description encompasses the full processing chain: from the image acquisition to the information extraction and data interpretation. The methods applied take advantage of existing tools and new, innovative and specific developments in order to acquire data on relevant ecological information concerning the structure and functioning of a red coral population. The tools presented here are based on: (i) automatic orientation using coded quadrats; (ii) use of non-photorealistic rendering (NPR) and 3D skeletonization techniques; (iii) computation of distances between colonies from a same site; and (iv) the use of a plenoptic approach in an underwater environment. © 2018 by the authors.This work is partially done in the framework of the PERfECT project, funded by the Foundation TOTAL, project 2014/257. The plenoptic camera was bought in the frame of the DGA RAPID LORI project (LOcalisation et Reconnaissance d’objets Immergés
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