Funders: the missing link in equitable global health research?

Global health research is mired by inequities, some of which are linked to current approaches to research funding. The role of funders and donors in achieving greater equity in global health research needs to be clearly defined. Imbalances of power and resources between high income countries (HICs) and low- and middle-income countries (LMICs) is such that many funding approaches do not centre the role of LMIC researchers in shaping global health research priorities and agenda. Relative to need, there is also disparity in financial investment by LMIC governments in health research. These imbalances put at a disadvantage LMIC health professionals and researchers who are at forefront of global health practice. Whilst many LMICs do not have the means (due to geopolitical, historical, and economic reasons) for direct investment, if those with means were to invest more of their own funds in health research, it may help LMICs become more self-sufficient and shift some of the power imbalances. Funders and donors in HICs should address inequities in their approach to research funding and proactively identify mechanisms that assure greater equity–including via direct funding to LMIC researchers and direct funding to build local LMIC-based, led, and run knowledge infrastructures. To collectively shape a new approach to global health research funding, it is essential that funders and donors are part of the conversation. This article provides a way to bring funders and donors into the conversation on equity in global health research

Brazils Highway BR-319: The road to the collapse of the Amazon and the violation of indigenous rights

One of the greatest threats to the Brazilian Amazon is the reconstruction and paving of the formerly abandoned Highway BR-319, which would link one of the most conserved blocks in the Amazon forest to the “arc of deforestation” on the southern edge of the region where most forest has already been destroyed. BR-319 and its planned side roads would allow the actors and processes from the arc of deforestation to move into vast areas of unprotected rainforest. In the specific case of this highway, a judicial decision that is not subject to further appeal established that environmental studies for the first section of the highway to be reconstructed (“Lot C”) must be carried out before paving. The federal highway department and the “Civil House” of President Bolsonaro’s presidential office ignored this decision and issued a call for bids for the construction work. Due to the current lack of governance in the BR-319 area and the history of deforestation whenever Amazonian highways are built, the decision on whether to suspend the contract for the “Lot C” is critical for the maintenance of both the ecosystem services of the Amazon forest and the way of life of indigenous and riverside people. This decision is expected to be made shortly by a single person

Capitalizing on opportunities provided by pasture sudden death to enhance livestock sustainable management in Brazilian Amazonia

Brazil has the largest commercial beef cattle stock on Earth, and most of the cattle produced in the country is bred and finished on pastures. The cattle ranching sector represents a significant source of the country's greenhouse gas (GHG) emissions. Agricultural intensification has been highlighted as one of the main strategies in reaching global food security and reducing deforestation. The Sudden Death Disease (SDD) of pastures, which affects the most planted cultivar of Urochloa brizantha, is degrading pastures in the Amazon, contributing to low production yields and high emission rates. This paper discusses the intensification of pasture production systems and SDD, to examine the potential for pasture renovation to address livestock productivity and GHG balance, emissions and potential sinks. Does SDD represent a blessing or a curse to climate change mitigation in the Brazilian Amazon? A collection of pasture samples were assessed to measure wet and dry weight in areas with and without SDD, which were related to remote sensing data to provide an overall estimate of the total area affected by the SDD in Alta Floresta, a municipal county of southern Brazilian Amazonia. We found that 77.1% of all pastures had been committed to the syndrome, which has forced farmers to renew their pastures. This also has great potential in increasing soil carbon stocks, effectively reducing the CO2 footprint of meat production in those areas. Therefore, we firmly believe that SDD management has provided an opportunity to rebalance the emissions/sequestration equation associated with meat production by the cattle ranching sector in this Amazonin frontier

Wildfire incidence throughout the Brazilian Pantanal is driven by local climate rather than bovine stocking density

The Pantanal is the world’s largest and most biodiverse continental sheet-flow wetland. Recently, vast tracts of the Pantanal have succumbed to the occurrence of fires, raising serious concerns over the future integrity of the biodiversity and ecosystem services of this biome, including revenues from ecotourism. These wildfires degrade the baseline of natural ecosystems and the ecotourism economy across the region. Local residents (“Pantaneiros”) anecdotally state that extensive cattle herbivory can solve the contemporary flammability problem of the Pantanal by controlling vegetation biomass, thereby preventing or reducing both fuel loads and fires across the region. Here, we examine the covariation between the presence and density of cattle and the incidence of fires across the Brazilian Pantanal. Variables assessed included bovine cattle density, SPI (Standardized Precipitation Index), GPP (Gross Primary Productivity)/biomass estimate, and fire foci along a 19-year time series (2001 to 2019). Our findings show that fire foci across the Pantanal biome are related to climatic variables, such as lower annual precipitation and higher annual drought indices (SPI) rather than to cattle stocking rates. Therefore, the notion of “cattle firefighting”, a popular concept often discussed in some academic circles, cannot be validated because cattle numbers are unrelated to aboveground phytomass. Gross primary productivity further invalidated the “cattle herbivory” hypothesis because GPP was found to be strongly correlated with cattle density but not with the spatial distribution of fires. Fires throughout the Pantanal are currently aggravated by the presence of livestock and result from a combination of extreme weather events and outdated agricultural practices

Estrutura morfológica do fígado de tambaqui Colossoma macropomum (Cuvier, 1818)

Este trabalho teve como objetivo descrever macro e microscopicamente o fígado do Tambaqui Colossoma macropomum, Teleósteo de água doce da Família Characidae, de grande interesse econômico da bacia Amazônica. Foram utilizados seis (6) exemplares jovens com idade entre seis meses e um ano, oriundos da Chácara Esteio, Alta Floresta, MT, que desenvolve principalmente a prática da piscicultura. O órgão foi fotodocumentado in situ e descrito macroscopicamente, em seguida procedeu-se a retirada de fragmentos deste, que foram processados pelas técnicas histológicas rotineiras para inclusão em parafina e coloração de HE. O fígado localizou-se ventral à bexiga natatória e craniodorsalmente ao estômago, apresentou coloração amarronzada a vermelho, constituído por três lobos hepáticos, o lobo lateral direito, o lobo lateral esquerdo e o lobo ventral. Microscopicamente, o parênquima era constituído por hepatócitos com formato que variou do arredondado irregular hexagonal ao redondo com núcleo grande e central, arranjados em cordões lineares limitados por sinusóides que irradiam para veias centrais, e com ausência de lóbulos hepáticos. As veias centrais estavam distribuídas pelo parênquima, enquanto que o espaço porta, na maioria das vezes, era constituído apenas por uma veia hepática e o ducto biliar, em outros locais foi observado, uma artéria e um ducto. Não foi observada a formação de tríades portais. Foram frequentemente observados melano macrófagos centrais dispersos pelo parênquima. O estudo morfofuncional do Aparelho Digestório de peixes da bacia Amazônica, se faz pertinente com vistas ao conhecimento do aproveitamento de ganho de peso e produção em alta escala para consumo humano e preservação da espécie, além da importância de estarem sendo utilizados como bioindicadores atualmente