The protective effects of self-compassion on alcohol-related problems among first nation adolescents

Given the disproportionate alcohol-related consequences experienced by North American Indigenous youth, there is a critical need to identify related risk and protective factors. Self-compassion, which has been found to mitigate the effects of trauma exposure, may serve as one such protective factor given the high degree of historical trauma and contemporary discrimination identified as contributing to the alcohol-related disparities experienced by Indigenous communities. However, no research has examined how self-compassion (i.e. the ability to be kind and accepting and to extend compassion toward oneself) plays a unique role in Indigenous peoples’ experiences with alcohol. First Nation adolescents between the ages of 11 and 18 living on a reserve in Eastern Canada (N = 106, Mage = 14.6, 50.0% female) completed a pencil-and-paper survey regarding their alcohol use, alcohol-related problems, and self-compassion. Self-compassion was significantly inversely associated with alcohol-related problems (b = -.51, p =.01, 95%CI [-.90, −.12], and significantly interacted with frequency of alcohol use in predicting alcohol-related problems (b = -.42, p =.04, 95%CI [-.82, −.03]). Simple slopes analyses revealed that the association between frequency of alcohol use and frequency of experiencing alcohol-related problems was significant and positive at low (b = 4.68, p \u3c.001, 95%CI [2.62, 6.73]), but was not significant at high (b = -.29, p =.89, 95%CI [−4.35, 3.77]) levels of self-compassion. Binary logistic regression revealed that higher scores of self-compassion were associated with a lower odds of being in the high-risk group for AUD (OR = 0.90, 95%CI [0.83, 0.98], p =.02). Our results suggest self-compassion may be protective against experiencing alcohol problems in Indigenous youth and thus may be a target for behavioral interventions

Testing the competing life reinforcers model for substance use in reserve-dwelling First Nation youth

PURPOSE: North American Indigenous (NAI) communities often cite substance misuse as problematic in their communities. The Competing Life Reinforcers (CLRs) model suggests that when reinforcers are valued, important, and incompatible with substance use, they will be associated with less substance misuse. Three categories of CLRs were identified in our formative work and include the following: cultural, social, and extracurricular activities. The aims of the current study were to test the associations among valuing and availability of CLRs and NAI adolescent alcohol and marijuana use. METHODS: Adolescents living in rural First Nation reserve communities (N = 106, 50.0% female) reported their substance use and perceived availability and valuing of CLRs (e.g., smudging and after school activities). FINDINGS: Greater value placed on cultural reinforcers was significantly associated with reduced likelihood of past 3-month drinking to get drunk (OR = 0.85, 95% CI[0.73, 0.98]). Greater value placed on social reinforcers was associated with lower likelihood of past 3-month drinking (OR = 0.94, 95% CI[0.89, 0.995]) and past-3 month drinking to get drunk (OR = 0.94, 95% CI[0.88, 0.99]). Greater valuing extracurricular activities were associated with lower likelihood of past month marijuana use (OR = 0.84, 95% CI[0.72, 098]), past 3-month drinking (OR = 0.77, 95% CI[0.64, 0.92]), and past 3-month drinking to get drunk (OR = 0.76, 95% CI[0.63, 0.92]). CONCLUSIONS: CLRs may be protective against NAI adolescent substance use and may be useful targets for prevention and treatment for NAI adolescent substance use. (PsycInfo Database Record (c) 2021 APA, all rights reserved)

Oral health 4 life: Design and methods of a semi-pragmatic randomized trial to promote oral health care and smoking abstinence among tobacco quitline callers

Smokers are at high risk for oral disease. As a result, they represent an important target group for population-level, public oral health promotion efforts. While dental health professionals often address smoking with their patients, no systematic efforts have been made to offer smokers an intervention to improve their use of oral health care. This paper details the rationale, design, and methods of a large, semi-pragmatic, randomized clinical trial designed to address this gap. Participants are recruited via the Oregon, Nebraska and Louisiana state-sponsored tobacco quitlines and randomized to receive standard quitline care versus standard care plus a multi-modal oral health promotion program (Oral Health 4 Life) integrated within the quitline services. All participants are followed for 6months to assess the impact of the intervention on smoking abstinence and utilization of professional dental care. In addition, the study will assess the cost of the intervention and provide practical guidance to states on whether the intervention is financially feasible to implement, should the intervention be effective. This study protocol may be useful to others interested in promoting oral health among smokers, those interested in partnering with tobacco quitlines to extend standard services to address other high risk health behaviors among smokers, or those interested in semi-pragmatic trial design

The NEALS primary lateral sclerosis registry

Primary lateral sclerosis (PLS) is a neurodegenerative disease characterized by progressive upper motor neuron dysfunction. Because PLS patients represent only 1 to 4% of patients with adult motor neuron diseases, there is limited information about the disease's natural history. The objective of this study was to establish a large multicenter retrospective longitudinal registry of PLS patients seen at Northeast ALS Consortium (NEALS) sites to better characterize the natural progression of PLS. Methods: Clinical characteristics, electrophysiological findings, laboratory values, disease-related symptoms, and medications for symptom management were collected from PLS patients seen between 2000 and 2015. Results: The NEALS registry included data from 250 PLS patients. Median follow-up time was 3 years. The mean rate of functional decline measured by ALSFRS-R total score was -1.6 points/year (SE:0.24, n = 124); the mean annual decline in vital capacity was -3%/year (SE:0.55, n = 126). During the observational period, 18 patients died, 17 patients had a feeding tube placed and 7 required permanent assistive ventilation. Conclusions: The NEALS PLS Registry represents the largest available aggregation of longitudinal clinical data from PLS patients and provides a description of expected natural disease progression. Data from the registry will be available to the PLS community and can be leveraged to plan future clinical trials in this rare disease