The SCRA Public Policy Committee in Action: Advocacy, Collaboration, and Capacity Building

Interest in social policy work has been on the rise in the Society for Community Research and Action (SCRA). SCRA’s Public Policy Committee aims to affect local, state, and national policy on topics relevant to community psychology through advocacy, collaboration, and capacity building. To communicate SCRA’s perspective on pressing social issues, the Public Policy Committee created a policy position statement procedure to address ongoing problems and a rapid response action procedure for urgent matters (e.g., advocacy campaigns). Options for dissemination of policy initiatives include The Community Psychologist (TCP), American Journal of Community Psychology (AJCP), SCRA listservs, and others. Examples of position statements approved or under development include mass incarceration, juvenile justice, immigration reform, and global climate change. Examples of past rapid response actions include the areas of gun legislation, sequester cuts, and psychologists’ involvement in torture. To expand SCRA’s policy reach, SCRA has partnered with other organizations in capacity building efforts. For example, SCRA and the Public Policy Committee partnered with the Society for the Psychological Study of Social Issues (SPSSI) to conduct a Short Course in Policy Involvement and an advocacy training day on Capitol Hill (United States Congress). Finally, the Public Policy Committee has engaged in strategic initiatives to increase the capacity of SCRA members to engage in policy and advocacy work. Strategic initiatives include the annual SCRA Public Policy Small Grants Program, student practicum positions on the Public Policy Committee, surveys of SCRA membership regarding policy and advocacy engagement, and a policy track at SCRA biennial conferences

The SCRA Public Policy Committee in Action: Advocacy, Collaboration, and Capacity Building

Interest in social policy work has been on the rise in the Society for Community Research and Action (SCRA). SCRA’s Public Policy Committee aims to affect local, state, and national policy on topics relevant to community psychology through advocacy, collaboration, and capacity building. To communicate SCRA’s perspective on pressing social issues, the Public Policy Committee created a policy position statement procedure to address ongoing problems and a rapid response action procedure for urgent matters (e.g., advocacy campaigns). Options for dissemination of policy initiatives include The Community Psychologist (TCP), American Journal of Community Psychology (AJCP), SCRA listservs, and others. Examples of position statements approved or under development include mass incarceration, juvenile justice, immigration reform, and global climate change. Examples of past rapid response actions include the areas of gun legislation, sequester cuts, and psychologists’ involvement in torture. To expand SCRA’s policy reach, SCRA has partnered with other organizations in capacity building efforts. For example, SCRA and the Public Policy Committee partnered with the Society for the Psychological Study of Social Issues (SPSSI) to conduct a Short Course in Policy Involvement and an advocacy training day on Capitol Hill (United States Congress). Finally, the Public Policy Committee has engaged in strategic initiatives to increase the capacity of SCRA members to engage in policy and advocacy work. Strategic initiatives include the annual SCRA Public Policy Small Grants Program, student practicum positions on the Public Policy Committee, surveys of SCRA membership regarding policy and advocacy engagement, and a policy track at SCRA biennial conferences

Community Psychology and Public Policy: Research, Advocacy and Training in International Contexts

We introduce a special issue on public policy research, advocacy, and training by community psychologists that grew out of the Fifth International Community Psychology Conference held in Fortaleza, Brazil. Two papers from Portugal propose changes in sex education policies in schools and communities to promote adolescents’ rights and drug abuse policies based on decriminalization of use and possession, risk and harm reduction, and health promotion. An article from Spain addresses transformative policies to reduce public health disparities for the Roma population in that country. Three contributions from Brazil examine a Landless Workers Movement popular education and agroforestry project to support children and adolescents’ rights and participation; another social movement to control public policy on youth and adult literacy and education; and racist environmental and natural resource policies that ignore the territorial rights of indigenous Amazonian populations. A paper from Chile describes the creation of a regular public forum to reduce stigma and promote human rights in community mental health care. Another paper examines the development and presents examples of social-community psychologists’ involvement in policy work in Puerto Rico, the process of training students for this endeavor and how to improve training. Finally, three articles cover recent trends in policy advocacy by community psychologists in the United States including its promotion and capacity building by the Society for Community Research and Action; using social media as a tool to enhance effectiveness of advocacy efforts; and an assessment of advocates’ and legislators’ capacity, knowledge, and perceptions of child injury prevention to inform policy change efforts

Community Psychology and Public Policy: Research, Advocacy and Training in International Contexts

We introduce a special issue on public policy research, advocacy, and training by community psychologists that grew out of the Fifth International Community Psychology Conference held in Fortaleza, Brazil. Two papers from Portugal propose changes in sex education policies in schools and communities to promote adolescents’ rights and drug abuse policies based on decriminalization of use and possession, risk and harm reduction, and health promotion. An article from Spain addresses transformative policies to reduce public health disparities for the Roma population in that country. Three contributions from Brazil examine a Landless Workers Movement popular education and agroforestry project to support children and adolescents’ rights and participation; another social movement to control public policy on youth and adult literacy and education; and racist environmental and natural resource policies that ignore the territorial rights of indigenous Amazonian populations. A paper from Chile describes the creation of a regular public forum to reduce stigma and promote human rights in community mental health care. Another paper examines the development and presents examples of social-community psychologists’ involvement in policy work in Puerto Rico, the process of training students for this endeavor and how to improve training. Finally, three articles cover recent trends in policy advocacy by community psychologists in the United States including its promotion and capacity building by the Society for Community Research and Action; using social media as a tool to enhance effectiveness of advocacy efforts; and an assessment of advocates’ and legislators’ capacity, knowledge, and perceptions of child injury prevention to inform policy change efforts

Characterization of the Physical Stability of a Lyophilized IgG1 mAb After Accelerated Shipping-like Stress

Upon exposure to shaking stress, an IgG1 mAb formulation in both liquid and lyophilized state formed subvisible particles. Since freeze-drying is expected to minimize protein physical instability under these conditions, the extent and nature of aggregate formation in the lyophilized preparation was examined using a variety of particle characterization techniques. The effect of formulation variables such as residual moisture content, reconstitution rate, and reconstitution medium were examined. Upon reconstitution of shake-stressed lyophilized mAb, differences in protein particle size and number were observed by Microflow Digital Imaging (MFI), with the reconstitution medium having the largest impact. Shake-stress had minor effects on the structure of protein within the particles as shown by SDS-PAGE and FTIR analysis. The lyophilized mAb was shake-stressed to different extents and stored for 3 months at different temperatures. Both extent of cake collapse and storage temperature affected the physical stability of the shake-stressed lyophilized mAb upon subsequent storage. These findings demonstrate that physical degradation upon shaking of a lyophilized IgG1 mAb formulation includes not only cake breakage, but also results in an increase in subvisible particles and turbidity upon reconstitution. The shaking-induced cake breakage of the lyophilized IgG1 mAb formulation also resulted in decreased physical stability upon storage

Learning to become an online editor: the editathon as a learning environment

This study explores Wikipedia as a site for learning. In particular it traces how people learn to become Wikipedia editors through engagement in an editathon, a training event for people who want to become a volunteer editor. The study is original in its emphasis on the various types of knowledge editors acquire as they develop expertise. Determining the knowledge needed to contribute to Wikipedia is significant in terms of understanding Wikipedia as a site for learning. Data was gathered from nine participants who took part in an ‘editathon’ event on the theme of the Edinburgh Seven. The study used a rigorous methodology, combining quantitative social network analysis, documenting the online activity of participants as they created and edited Wikipedia pages, with qualitative interviews, which recorded participants reflections on their participation in the editathon. A key finding is that conceptual and procedural knowledge are representative of the foundational knowledge needed to contribute to Wikipedia actively as an editor. However, this knowledge on its own is not sufficient. Editors also develop socio-cultural and relational knowledge forms of knowledge to enable them to operate and problem-solve effectively. The relationship between the physical and the digital is important, since socio-cultural and relational knowledge are developed through active experimentation as the editathon engage with physical objects to create the online wiki pages

Prediction of Breast Cancer-Related Lymphedema By Dermal Backflow Detected With Near-infrared Fluorescence Lymphatic Imaging

PURPOSE: Mild breast cancer-related lymphedema (BCRL) is clinically diagnosed as a 5%-10% increase in arm volume, typically measured no earlier than 3-6 months after locoregional treatment. Early BCRL treatment is associated with better outcomes, yet amid increasing evidence that lymphedema exists in a latent form, treatment is typically delayed until arm swelling is obvious. In this study, we investigated whether near-infrared fluorescence lymphatic imaging (NIRF-LI) surveillance could characterize early onset of peripheral lymphatic dysfunction as a predictor of BCRL. METHODS: In a prospective, longitudinal cohort/observational study (NCT02949726), subjects with locally advanced breast cancer who received axillary lymph node dissection and regional nodal radiotherapy (RT) were followed serially, between 2016 and 2021, before surgery, 4-8 weeks after surgery, and 6, 12, and 18 months after RT. Arm volume was measured by perometry, and lymphatic (dys) function was assessed by NIRF-LI. RESULTS: By 18 months after RT, 30 of 42 study subjects (71%) developed mild-moderate BCRL (i.e., ≥ 5% arm swelling relative to baseline), all manifested by dermal backflow of lymph into lymphatic capillaries or interstitial spaces. Dermal backflow had an 83% positive predictive value and 86% negative predictive value for BCRL, with a sensitivity of 97%, specificity of 50%, accuracy of 83%, positive likelihood ratio of 1.93, negative likelihood ratio of 0.07, and odds ratio of 29.00. Dermal backflow appeared on average 8.3 months, but up to 23 months, before the onset of mild BCRL. CONCLUSION: BCRL can be predicted by dermal backflow, which often appears months before arm swelling, enabling early treatment before the onset of edema and irreversible tissue changes

2005 AAPP Monograph Series

The African American Professors Program (AAPP) at the University of South Carolina is proud to publish the fifth edition of its annual monograph series. The program recognizes the significance of offering its scholars avenue to engage actively in research and publish papers related thereto. Parallel with the publication of their refereed manuscripts is the opportunity to gain visibility among scholars throughout institutions worldwide. Scholars who have contributed manuscripts for this monograph are to be commended for adding this additional responsibility to their academic workload. Writing across disciplines adds to the intellectual diversity of these papers. From neophytes, relatively speaking, to an array of very experienced individuals, the chapters have been researched and comprehensively written. Founded in 1997 through the Department of Educational Leadership and Policies in the College of Education, AAPP was designed to address the underrepresentation of African American professors on college and university campuses. Its mission is to expand the pool of these professors in critical academic and research areas. Sponsored by the University of South Carolina, the W. K. Kellogg Foundation, and the South Carolina General Assembly, the program recruits doctoral students for disciplines in which African Americans currently are underrepresented among faculty in higher education. The continuation of this monograph series is seen as responding to a window of opportunity to be sensitive to an academic expectation of graduates as they pursue career placement and, at the same time, one that allows for the dissemination of AAPP products to a broader community. The importance of this monograph series has been voiced by one of our 2002 AAPP graduates, Dr. Shundele LaTjuan Dogan, a recent Administrative Fellow at Harvard University and now a Program Officer for the Southern Education Foundation, Atlanta, Georgia. Dr. Dogan wrote: One thing in particular that I want to thank you for is having the African American Professors Program scholars publish articles for the monograph. I have to admit that writing the articles seemed like extra work at the time. However, in my recent interview process, organizations have asked me for samples of my writing. Including an article from a published monograph helped to make my portfolio much more impressive. You were \u27right on target\u27 in having us do the monograph series. (MPP 2003 Monograph, p. xi) The African American Professors Program offers this 2005 publication as a contribution to its readership and hopes that you will be inspired by this select group of manuscripts. John McFadden, Ph.D. The Benjamin Elijah Mays Professor Director, African American Professors Program University of South Carolinahttps://scholarcommons.sc.edu/mcfadden_monographs/1007/thumbnail.jp

The Multifunctional LigB Adhesin Binds Homeostatic Proteins with Potential Roles in Cutaneous Infection by Pathogenic Leptospira interrogans

Leptospirosis is a potentially fatal zoonotic disease in humans and animals caused by pathogenic spirochetes, such as Leptospira interrogans. The mode of transmission is commonly limited to the exposure of mucous membrane or damaged skin to water contaminated by leptospires shed in the urine of carriers, such as rats. Infection occurs during seasonal flooding of impoverished tropical urban habitats with large rat populations, but also during recreational activity in open water, suggesting it is very efficient. LigA and LigB are surface localized proteins in pathogenic Leptospira strains with properties that could facilitate the infection of damaged skin. Their expression is rapidly induced by the increase in osmolarity encountered by leptospires upon transition from water to host. In addition, the immunoglobulin-like repeats of the Lig proteins bind proteins that mediate attachment to host tissue, such as fibronectin, fibrinogen, collagens, laminin, and elastin, some of which are important in cutaneous wound healing and repair. Hemostasis is critical in a fresh injury, where fibrinogen from damaged vasculature mediates coagulation. We show that fibrinogen binding by recombinant LigB inhibits fibrin formation, which could aid leptospiral entry into the circulation, dissemination, and further infection by impairing healing. LigB also binds fibroblast fibronectin and type III collagen, two proteins prevalent in wound repair, thus potentially enhancing leptospiral adhesion to skin openings. LigA or LigB expression by transformation of a nonpathogenic saprophyte, L. biflexa, enhances bacterial adhesion to fibrinogen. Our results suggest that by binding homeostatic proteins found in cutaneous wounds, LigB could facilitate leptospirosis transmission. Both fibronectin and fibrinogen binding have been mapped to an overlapping domain in LigB comprising repeats 9–11, with repeat 11 possibly enhancing binding by a conformational effect. Leptospirosis patient antibodies react with the LigB domain, suggesting applications in diagnosis and vaccines that are currently limited by the strain-specific leptospiral lipopolysaccharide coats

On the notion of home and the goals of palliative care

The notion of home is well known from our everyday experience, and plays a crucial role in all kinds of narratives about human life, but is hardly ever systematically dealt with in the philosophy of medicine and health care. This paper is based upon the intuitively positive connotation of the term “home.” By metaphorically describing the goal of palliative care as “the patient’s coming home,” it wants to contribute to a medical humanities approach of medicine. It is argued that this metaphor can enrich our understanding of the goals of palliative care and its proper objectives. Four interpretations of “home” and “coming home” are explored: (1) one’s own house or homelike environment, (2) one’s own body, (3) the psychosocial environment, and (4) the spiritual dimension, in particular, the origin of human existence. Thinking in terms of coming home implies a normative point of view. It represents central human values and refers not only to the medical-technical and care aspects of health care, but also to the moral context