Survival in pulmonary fibrosis combined with emphysema: likely defined by characteristics of specific patient subpopulations

Authors' Reply to letter from Cottin et al

Challenges for ecolabeling growth: lessons from the EU Ecolabel in Spain

Purpose The European Ecolabel (EU Flower) has the mission to encourage cleaner production and influence consumers to promote Europe's transition to a circular economy. Nonetheless, little is known about EU Ecolabel evolution; it is not clear what the drivers that encourage its implementation are. Thus, this study aims to assess the growing acceptance of the EU Ecolabel in the European Union, and Spain more specifically, by examining product and service categories and geographical regions. Methods The methodological approach taken in this study is a mixed methodology based on the triangulation method by consulting the EU Ecolabel scheme database, EU Ecolabel delegates from some autonomous regions, and the academic literature. Also, a geographic analysis was run in the ArcGIS Software with data about the accumulation of licenses assigned in 2016. Results and discussion The analysis shows that most products in Spain that have been awarded the EU Ecolabel belong to the following categories: Do-It-Yourself Products (paint and varnish), Paper Products, Cleaning Up Products, and Electronic Equipment. At the same time, the study showed that this ecolabel faces significant obstacles in its diffusion, such as the competition with environmental labels launched previously in Europe and other regional labels. Conclusions The results of this study indicate the existence of five drivers that may encourage the implementation of EU Flower in a region: (1) public management, (2) communication strategy, (3) sustainable public procurement criteria, (4) local income per capita, and (5) international trade incentives. Finally, this study provides essential recommendations for policymakers to trigger ecolabeling practices such as the need to improve the understanding of the EU ecolabel impact in different levels of activity, which means countries, regions, industrial clusters, firms, and consumers. Also, this investigation identifies areas for further research, and it expresses the need to develop business case studies about ecolabeling with the objective to visualize this phenomenon as an eco-innovation process

Characterizing SL2S galaxy groups using the Einstein radius

We analyzed the Einstein radius, $\theta_E$, in our sample of SL2S galaxy groups, and compared it with $R_A$ (the distance from the arcs to the center of the lens), using three different approaches: 1.- the velocity dispersion obtained from weak lensing assuming a Singular Isothermal Sphere profile ($\theta_{E,I}$), 2.- a strong lensing analytical method ($\theta_{E,II}$) combined with a velocity dispersion-concentration relation derived from numerical simulations designed to mimic our group sample, 3.- strong lensing modeling ($\theta_{E,III}$) of eleven groups (with four new models presented in this work) using HST and CFHT images. Finally, $R_A$ was analyzed as a function of redshift $z$ to investigate possible correlations with L, N, and the richness-to-luminosity ratio (N/L). We found a correlation between $\theta_{E}$ and $R_A$, but with large scatter. We estimate $\theta_{E,I}$ = (2.2 $\pm$ 0.9) + (0.7 $\pm$ 0.2)$R_A$, $\theta_{E,II}$ = (0.4 $\pm$ 1.5) + (1.1 $\pm$ 0.4)$R_A$, and $\theta_{E,III}$ = (0.4 $\pm$ 1.5) + (0.9 $\pm$ 0.3)$R_A$ for each method respectively. We found a weak evidence of anti-correlation between $R_A$ and $z$, with Log$R_A$ = (0.58$\pm$0.06) - (0.04$\pm$0.1)$z$, suggesting a possible evolution of the Einstein radius with $z$, as reported previously by other authors. Our results also show that $R_A$ is correlated with L and N (more luminous and richer groups have greater $R_A$), and a possible correlation between $R_A$ and the N/L ratio. Our analysis indicates that $R_A$ is correlated with $\theta_E$ in our sample, making $R_A$ useful to characterize properties like L and N (and possible N/L) in galaxy groups. Additionally, we present evidence suggesting that the Einstein radius evolves with $z$.Comment: Accepted for publication in Astronomy & Astrophysics. Typos correcte

Reconfiguración de nanopartículas de plata obtenidas por ablación láser en líquido

Estudia la reconfiguración de la nanopartículas de plata coloidal, obtenidos por ablación láser en líquido a diferentes pulsos láser y su caracterización por espectroscopia de absorción UV-Vis y microscopia STEM

Discriminating the short-term action of root and foliar application of humic acids on plant growth: emerging role of jasmonic acid

Humic substances (HS, fulvic and humic acids) are widely used as fertilizers or plant growth stimulants, although their mechanism of action still remains partially unknown. Humic substances may be applied either directly to the soil or as foliar sprays. Despite both kind of application are commonly used in agricultural practices, most of the studies regarding the elicited response in plants induced by HS are based on the root-application of these substances. The present work aimed at discriminating between the mechanisms of action of foliar application versus root application of a sedimentary humic acid (SHA) on plant development. For this purpose, six markers related to plant phenotype, plant morphology, hormonal balance and root-plasma membrane H+-ATPase were selected. Both application strategies improved the shoot and root growth. Foliar applied- and root applied-SHA shared the capacity to increase the concentration of indole-3-acetic acid in roots and cytokinins in shoots. However, foliar application did not lead to short-term increases in either abscisic acid root-concentration or root-plasma membrane H+-ATPase activity which are, however, two crucial effects triggered by SHA root-application. Both application modes increased the root concentrations of jasmonic acid and jasmonoyl-isoleucine. These hormonal changes caused by foliar application could be a stress-related symptom and connected to the loss of leaves trichomes and the diminution of chloroplasts size seen by scanning electron microscopy. These results support the hypothesis that the beneficial effects of SHA applied to roots or leaves may result from plant adaptation to a mild transient stress caused by SHA application

Genotype-by-Environment Interaction in Interspecific \u3cem\u3eUrochloa\u3c/em\u3e Hybrids Using Factor Analytic Models

Environmental factors can influence plant phenotypes shaping the expression of pastures. The ability to test genotypes in multiple environments is critical in a breeding program because important traits are heavily influenced by the environment. Nutritional quality is critical in forage breeding because it affects the rate of live weight gain in livestock as well as the quality of end products such as milk and meat. However, there is not much information on the environmental effect on agronomic and nutritional quality traits in tropical forages. For this reason, the objective of the present study was to investigate the genotype-by-environment interaction in a breeding population of interspecific Urochloa hybrids evaluated for agronomic and nutritional quality traits across four locations in Colombia, using factor analytic mixed models. Phenotypic correlations among traits ranged from 0.26 (plant area vs dry weight) to 0.93 (fresh weight vs dry weight), indicating a strong interaction in some traits. Genetic correlations among environments showed different ranges depending on the variable evaluated. For example, plant height genetic correlations among environments ranged from 0.16 to 0.9, indicating high genotype-byenvironment interaction. The factor analytic analysis revealed that two factors explained more than 60% of the genetic variance in all traits evaluated and that 80% of the environments were clustered in the first factor. Factor analytic biplot indicates that Llanos location differed strongly from other locations evaluated. Based on the results obtained, the factor analytic analysis is a useful tool to stratify environments and identify Urochloa cultivars adapted to different ecological niches

Human Blood Lipoprotein Predictions from ¹H NMR Spectra:Protocol, Model Performances, and Cage of Covariance

Lipoprotein subfractions are biomarkers for the early diagnosis of cardiovascular diseases. The reference method, ultracentrifugation, for measuring lipoproteins is time-consuming, and there is a need to develop a rapid method for cohort screenings. This study presents partial least-squares regression models developed using 1H nuclear magnetic resonance (NMR) spectra and concentrations of lipoproteins as measured by ultracentrifugation on 316 healthy Danes. This study explores, for the first time, different regions of the 1H NMR spectrum representing signals of molecules in lipoprotein particles and different lipid species to develop parsimonious, reliable, and optimal prediction models. A total of 65 lipoprotein main and subfractions were predictable with high accuracy, Q2 of >0.6, using an optimal spectral region (1.4-0.6 ppm) containing methylene and methyl signals from lipids. The models were subsequently tested on an independent cohort of 290 healthy Swedes with predicted and reference values matching by up to 85-95%. In addition, an open software tool was developed to predict lipoproteins concentrations in human blood from standardized 1H NMR spectral recordings

From thermal rectifiers to thermoelectric devices

We discuss thermal rectification and thermoelectric energy conversion from the perspective of nonequilibrium statistical mechanics and dynamical systems theory. After preliminary considerations on the dynamical foundations of the phenomenological Fourier law in classical and quantum mechanics, we illustrate ways to control the phononic heat flow and design thermal diodes. Finally, we consider the coupled transport of heat and charge and discuss several general mechanisms for optimizing the figure of merit of thermoelectric efficiency.Comment: 42 pages, 22 figures, review paper, to appear in the Springer Lecture Notes in Physics volume "Thermal transport in low dimensions: from statistical physics to nanoscale heat transfer" (S. Lepri ed.