13 research outputs found
Myofascial Release Therapy in the Treatment of Occupational Mechanical Neck Pain: A Randomized Parallel Group Study
Objective: As myofascial release therapy is currently under development, the objective of this study was to compare the effectiveness of myofascial release therapy with manual therapy for treating occupational mechanical neck pain. Design: A randomized, single-blind parallel group study was developed. The sample (n = 59) was divided into GI, treated with manual therapy, and GII, treated with myofascial release therapy. Variables studied were intensity of neck pain, cervical disability, quality of life, craniovertebral angle, and ranges of cervical motion. Results: At five sessions, clinical significance was observed in both groups for all the variables studied, except for flexion in GI. At this time point, an intergroup statistical difference was observed, which showed that GII had better craniovertebral angle (P = 0.014), flexion (P = 0.021), extension (P = 0.003), right side bending (P = 0.001), and right rotation (P = 0.031). A comparative analysis between therapies after intervention showed statistical differences indicating that GII had better craniovertebral angle (P = 0.000), right (P = 0.000) and left (P = 0.009) side bending, right (P = 0.024) and left (P = 0.046) rotations, and quality of life. Conclusions: The treatment of occupational mechanical neck pain by myofascial release therapy seems to be more effective than manual therapy for correcting the advanced position of the head, recovering range of motion in side bending and rotation, and improving quality of life
The mitochondrial inhibitor oligomycin induces an inflammatory response in the rat knee joint
[Abstract]
Background. Recent findings support a connection between mitochondrial dysfunction and activation of inflammatory pathways in articular cells. This study investigates in vivo in an acute model whether intra-articular administration of oligomycin, an inhibitor of mitochondrial function, induces an oxidative and inflammatory response in rat knee joints.
Methods. Oligomycin was injected into the rat left knee joint on days 0, 2, and 5 before joint tissues were obtained on day 6. The right knee joint served as control. Results were evaluated by macroscopy and histopathology and by measuring cellular and mitochondrial reactive oxygen species (ROS), 4-hydroxy-2-nonenal (4-HNE, a marker of lipid peroxidation), nuclear factor erythroid 2-related factor 2 (Nrf2), and CD68 (macrophages) and chemokine levels. The marker of mitochondrial mass COX-IV was also evaluated.
Results. The macroscopic findings showed significantly greater swelling in oligomycin-injected knees than in control knees. Likewise, the histological score of synovial damage was also increased significantly. Immunohistochemical studies showed high expression of IL-8, coinciding with a marked infiltration of polymorphonuclears and CD68+ cells in the synovium. Mitochondrial mass was increased in the synovium of oligomycin-injected joints, as well as cellular and mitochondrial ROS production, and 4-HNE. Relatedly, expression of the oxidative stress-related transcription factor Nrf2 was also increased. As expected, no histological differences were observed in the cartilage; however, cytokine-induced neutrophil chemoattractant-1 mRNA and protein expression were up-regulated in this tissue.
Conclusions. Mitochondrial failure in the joint is able to reproduce the oxidative and inflammatory status observed in arthritic joints.Instituto de Salud Carlos III; 09/02340Instituto de Salud Carlos III, RD12/0009/0018, RIERGalicia. Consellería de Innovación, Industria e Comercio; PXIB916357PRInstituto de Salud Carlos III; PI12/02771Xunta de Galicia; PS09/56Galicia. Consellería de Economía e Industria; INCITE 09E1R916139ESGalicia. Consellería de Economía e Industria; IN845B2010/176Galicia. Consellería de Economía e Industria; 10CSA916035P
Técnicas y tecnologías en hidrología médica e hidroterapia
El objetivo del presente informe es difundir entre los profesionales médicos la información que contribuya a orientarles en la materia, conocer las aplicaciones terapéuticas o rehabilitadoras que pueden ofrecer los distintos centros termales y explorar su interacción con los tratamientos médicos habituales a los que suelen estar sometidos los usuarios de estos programas de termalismo
Aportacion a la cura balneoterapica en el balneario de Lugo
Centro de Informacion y Documentacion Cientifica (CINDOC). C/Joaquin Costa, 22. 28002 Madrid. SPAIN / CINDOC - Centro de Informaciòn y Documentaciòn CientìficaSIGLEESSpai
Actualidad de la medicina termal
[Resumen] El uso del agua minero-medicinal, arraigado en la cultura occidental desde muy antiguo, ha
persistido hasta la actualidad con gran vigencia como una tradicional modalidad terapéutica
complementaria en diversas enfermedades crónicas. La Hidrología médica, balneoterapia o
medicina termal comprende un amplio espectro de modalidades terapéuticas que utilizan las
aguas minero-medicinales y productos termales acompañados de otros recursos terapéuticos
fundamentalmente medicina física, educación sanitaria, ejercicio, dieta y factores ambienta-
les, utilizados durante la estancia en un establecimiento termal. A partir de finales de los
años 80 del siglo pasado, la hidrología médica comienza a adquirir una nueva dimensión y
reconocimiento debido a diversos factores derivados de los importantes cambios en la
demografía socio-sanitaria actual y a los avances en la investigación orientada a demostrar
la eficacia terapéutica con las bases metodológicas de la Medicina basada en la evidencia.
También la investigación básica ha hecho importantes avances en el conocimiento de los
mecanismos de acción de la balneoterapia permitiendo establecer un enfoque científico
actual de la medicina termal. En la actualidad, los tratamientos termales se utilizan con 3
objetivos: el manejo de enfermedades crónicas habitualmente acompañadas de comorbilidad,
siendo la patología músculo-esquelética la más frecuente, seguida a gran distancia por las
enfermedades respiratorias; en segundo lugar, en la prevención de enfermedades comunes, y
en tercer lugar en la recuperación después de procesos agudos y en la rehabilitación.[Abstract] The use of mineral-medicinal water, ingrained in Western culture since ancient times, has
persisted until today with great validity as a traditional complementary therapeutic modality
in various chronic diseases. Medical Hydrology, Balneotherapy or Thermal medicine
comprises a wide spectrum of therapeutic modalities that use mineral-medicinal waters and
thermal products accompanied by other therapeutic resources, mainly physical medicine, health education, exercise, diet and environmental factors, used during the stay in a thermal
establishment. Since the late 80s of the last century, medical hydrology begins to acquire a
new dimension and recognition due to various factors derived from the important changes in
current socio-sanitary demography and to advances in research aimed at demonstrating
therapeutic efficacy with the methodological bases of evidence-based medicine. Basic
research has also made important advances in the knowledge of the mechanisms of action of
balneotherapy allowing to establish a current scientific approach to thermal medicine.
Currently, thermal treatments are used with 3 objectives: the management of chronic diseas-
es usually accompanied by comorbidity, with musculoskeletal pathology being the most
frequent, followed at a great distance by respiratory diseases; secondly in the prevention of
common diseases, and thirdly in recovery after acute processes and in rehabilitation medi-
cine
Medicina termal en enfermedades reumáticas: evidencia científica y actualidad de los mecanismos de acción
[Resumen] La patología músculo-esquelética es la responsable en la actualidad de la mayoría de las prescripciones de la curas termales en diversos países. La eficacia de la balneoterapia en reumatología, ha sido confirmada con una importante cantidad de ensayos clínicos aleatorizados, publicados en las dos últimas décadas, que le han permitido ganar en la comunidad científica internacional cierto grado de consenso acerca de su efectividad especialmente en artrosis de miembros y raquialgias. En los últimos años se han hecho además importantes avances en el conocimiento de los mecanismos de acción a través de los cuales se producen los reconocidos efectos terapéuticos de la balneoterapia en los pacientes con artrosis y patologías músculo-esqueléticas. Estos mecanismos son complejos y multifactoriales interviniendo sobre el control del dolor y sobre el daño tisular generador de fenómenos nociceptivos e inflamatorios. La cura termal produce efectos fisiológicos locales y generales en el organismo, que se ejercen a través de las propiedades físicas (especialmente calor y presión hidrostática), y de las propiedades químicas y biológicas del agua mineral, de los peloides y gases. Estos efectos van a contribuir a acelerar los fenómenos de reparación a nivel tisular, celular y molecular. En la actualidad, los avances científicos están permitiendo ampliar los conocimientos sobre los efectos en el organismo de las diferentes características físicoquímicas de las aguas mineromedicinales y en concreto de las aguas sulfuradas, mostrando efectos antiinflamatorios, antioxidantes, anticatabólicos y protectores en el cartílago articular.[Abstract] Musculoskeletal pathology is currently responsible for most of the prescriptions for thermal cures in various countries. The efficacy of balneotherapy in rheumatology has been confirmed with a significant number of randomized clinical trials, published in the last two decades, which have allowed it to gain some degree of consensus in the international scientific community about its effectiveness especially in osteoarthritis of limbs and spinal pain.
In recent years, important advances have also been made in the knowledge of the mechanisms of action through which the recognized therapeutic effects of balneotherapy occur in patients with osteoarthritis and musculoskeletal pathologies. These mechanisms are complex and multifactorial, intervening on pain control and on tissue damage that generates nociceptive and inflammatory phenomena. The thermal cure produces local and general physiological effects in the organism, which are exerted through the physical properties (especially heat and hydrostatic pressure), and the chemical and biological properties of mineral water, peloids and gases. These effects will contribute to accelerate the phenomena of repair at the tissue, cellular and molecular levels. At present, scientific advances are making it possible to broaden knowledge about the effects on the body of the different physicochemical characteristics of mineral-medicinal waters and in particular of sulphurous waters, showing antiinflammatory, antioxidant, anti-catabolic and protective effects on articular cartilage
Revista galega do ensino
Se describen los objetivos generales y los distintos tipos de Fisioterapia. A continuación, se explica el plan de estudios de la carrera, que se realiza en 3 años, donde se deben adquirir unos conocimientos básico de Anatomía, Fisiología y Patología y una formación más específica con las materias complementarias y optativas. Después, se exponen las actitudes que debe tener un fisioterapeuta y las salidas profesionales existentes.GaliciaBiblioteca de Educación del Ministerio de Educación, Cultura y Deporte; Calle San Agustín, 5 - 3 Planta; 28014 Madrid; Tel. +34917748000; [email protected]