2,169 research outputs found
The hullaballoo over e-learning? Technology and pluralism in economics
E-learning vs. “talk and chalk”: this binary opposition presents a conflict that has dominated existing pedagogical research. That technological innovation offers an alternative for pressured educationists to improve efficiency and question the cost-effectiveness of traditional teaching methods creates a false dichotomy. This paper addresses the influence of the erroneous “either/or” position and discards it. It claims that there is no fundamental antagonism between the two methods of instruction and proffers the alternative found in blended learning methods. The meticulous splicing of e-learning and traditional lectures liberates the Economics lecturer to deliver a pluralist perspective. Thus, technology becomes a vital tool enabling educators to escape from the limitation of monist teaching methods and guarantees that economics students can fully engage with the discipline’s vibrant debates. “Contest and controversy; orthodoxy and heterodoxy; critique and reject”: technology’s real role is to facilitate a workable space for the free thinking mind
Efficacy of Online Training for Improving Camp Staff Competency
Preparing competent staff is a critical issue within the camp community. This quasi-experimental study examined the effectiveness of an online course for improving staff competency in camp healthcare practices among college-aged camp staff and a comparison group (N = 55). We hypothesized that working in camp would increase competency test scores due to opportunities for staff to experientially apply knowledge learned online. Hierarchical linear modeling was used to analyse the cross-level effects of a between-individuals factor (assignment to experimental or comparison group) and within-individual effects of time (pre-test, post-test #1, and post-test #2) on online course test scores. At post-test #2, the difference in average test scores between groups was ~30 points, with the treatment group scoring lower on average than the comparison group. Factors that may have influenced these findings are explored, including fatigue and the limited durability of online learning. Recommendations for research and practice are discussed
Hypothalamic CaMKK2 Contributes to the Regulation of Energy Balance
SummaryDetailed knowledge of the pathways by which ghrelin and leptin signal to AMPK in hypothalamic neurons and lead to regulation of appetite and glucose homeostasis is central to the development of effective means to combat obesity. Here we identify CaMKK2 as a component of one of these pathways, show that it regulates hypothalamic production of the orexigenic hormone NPY, provide evidence that it functions as an AMPKα kinase in the hypothalamus, and demonstrate that it forms a unique signaling complex with AMPKα and β. Acute pharmacologic inhibition of CaMKK2 in wild-type mice, but not CaMKK2 null mice, inhibits appetite and promotes weight loss consistent with decreased NPY and AgRP mRNAs. Moreover, the loss of CaMKK2 protects mice from high-fat diet-induced obesity, insulin resistance, and glucose intolerance. These data underscore the potential of targeting CaMKK2 as a therapeutic intervention
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创新教学报告2015 —探索教学、学习与评价的新形式 [Innovating Pedagogy 2015]
本报告提出了在教学应用方面呈现端倪的“十大创新教学法”,包括跨界学习、论证学习、随机 学习、基于情境的学习、计算思维、利用远程实验室在科学实验中学习、具身学习、适应性教学、情绪分析 和隐性评价,预期这些方法有可能在教育实践中,尤其是在学校后继续教育中引发重大变革
Import of cytochrome c into mitochondria
The import of cytochrome c into mitochondria can be resolved into a number of discrete steps. Here we report on the covalent attachment of heme to apocytochrome c by the enzyme cytochrome c heme lyase in mitochondria from Neurospora crassa.
A new method was developed to measure directly the linkage of heme to apocytochrome c. This method is independent of conformational changes in the protein accompanying heme attachment. Tryptic peptides of [35S]cysteine-labelled apocytochrome c, and of enzymatically formed holocytochrome c, were resolved by reverse-phase HPLC. The cysteine-containing peptide to which heme was attached eluted later than the corresponding peptide from apocytochrome c and could be quantified by counting 35S radioactivity as a measure of holocytochrome c formation. Using this procedure, the covalent attachment of heme to apocytochrome c, which is dependent on the enzyme cytochrome c heme lyase, could be measured. Activity required heme (as hemin) and could be reversibly inhibited by the analogue deuterohemin. Holocytochrome c formation was stimulated 5–10-fold by NADH > NADPH > glutathione and was independent of a potential across the inner mitochondrial membrane. NADH was not required for the binding of apocytochrome c to mitochondria and was not involved in the reduction of the cysteine thiols prior to heme attachment. Holocytochrome c formation was also dependent on a cytosolic factor that was necessary for the heme attaching step of cytochrome c import. The factor was a heat-stable, protease-insensitive, low-molecular-mass component of unknown function.
Cytochrome c heme lyase appeared to be a soluble protein located in the mitochondrial intermembrane space and was distinct from the previously identified apocytochrome c binding protein having a similar location. A model is presented in which the covalent attachment of heme by cytochrome c heme lyase also plays an essential role in the import pathway of cytochrome c
Estimation of wood volume and height of olive tree plantations using airborne discrete-return LiDAR data
The aim of this study is to analyze methodologies based on airborne LiDAR (light detection and ranging) technology of low pulse density points (0.5m(-2)) for height and volume quantification of olive trees in Viver (Spain). A total of 29 circular plots, each with a radius of 20m, were sampled and their volumes and heights were obtained by dendrometric methods. For these estimations, several statistics derived from LiDAR data were calculated in each plot. Regression models were used to predict volume and height. The results showed good performance for estimating volume (R-2=0.70) and total height (R-2=0.67).The authors appreciate the financial support provided by the Spanish Ministerio de Ciencia e Innovacion (Ministry for Science & Innovation) within the framework of the project AGL2010-15334 and by the Vice-Rectorate for Research of the Universitat Politecnica de Valencia [Grant PAID-06-12-3297; SP20120534].Estornell Cremades, J.; Velázquez Martí, B.; López Cortés, I.; Salazar Hernández, DM.; Fernández-Sarría, A. (2014). Estimation of wood volume and height of olive tree plantations using airborne discrete-return LiDAR data. GIScience and Remote Sensing. 51(1):17-29. https://doi.org/10.1080/15481603.2014.883209S1729511Estornell, J., Ruiz, L. A., Velázquez-Martí, B., & Fernández-Sarría, A. (2011). Estimation of shrub biomass by airborne LiDAR data in small forest stands. Forest Ecology and Management, 262(9), 1697-1703. doi:10.1016/j.foreco.2011.07.026García, M., Riaño, D., Chuvieco, E., & Danson, F. M. (2010). Estimating biomass carbon stocks for a Mediterranean forest in central Spain using LiDAR height and intensity data. Remote Sensing of Environment, 114(4), 816-830. doi:10.1016/j.rse.2009.11.021Hyyppa, J., Kelle, O., Lehikoinen, M., & Inkinen, M. (2001). A segmentation-based method to retrieve stem volume estimates from 3-D tree height models produced by laser scanners. IEEE Transactions on Geoscience and Remote Sensing, 39(5), 969-975. doi:10.1109/36.921414Kim, Y., Yang, Z., Cohen, W. B., Pflugmacher, D., Lauver, C. L., & Vankat, J. L. (2009). Distinguishing between live and dead standing tree biomass on the North Rim of Grand Canyon National Park, USA using small-footprint lidar data. Remote Sensing of Environment, 113(11), 2499-2510. doi:10.1016/j.rse.2009.07.010Moorthy, I., Miller, J. R., Berni, J. A. J., Zarco-Tejada, P., Hu, B., & Chen, J. (2011). Field characterization of olive (Olea europaea L.) tree crown architecture using terrestrial laser scanning data. Agricultural and Forest Meteorology, 151(2), 204-214. doi:10.1016/j.agrformet.2010.10.005Næsset, E. (2004). Accuracy of forest inventory using airborne laser scanning: evaluating the first nordic full-scale operational project. Scandinavian Journal of Forest Research, 19(6), 554-557. doi:10.1080/02827580410019544Popescu, S. C. (2007). Estimating biomass of individual pine trees using airborne lidar. Biomass and Bioenergy, 31(9), 646-655. doi:10.1016/j.biombioe.2007.06.022Popescu, S. C., Wynne, R. H., & Nelson, R. F. (2002). Estimating plot-level tree heights with lidar: local filtering with a canopy-height based variable window size. Computers and Electronics in Agriculture, 37(1-3), 71-95. doi:10.1016/s0168-1699(02)00121-7Velázquez-Martí, B., Estornell, J., López-Cortés, I., & Martí-Gavilá, J. (2012). Calculation of biomass volume of citrus trees from an adapted dendrometry. Biosystems Engineering, 112(4), 285-292. doi:10.1016/j.biosystemseng.2012.04.011Velázquez-Martí, B., Fernández-González, E., Estornell, J., & Ruiz, L. A. (2010). Dendrometric and dasometric analysis of the bushy biomass in Mediterranean forests. Forest Ecology and Management, 259(5), 875-882. doi:10.1016/j.foreco.2009.11.027Velázquez-Martí, B., Fernández-González, E., López-Cortés, I., & Salazar-Hernández, D. M. (2011). Quantification of the residual biomass obtained from pruning of trees in Mediterranean olive groves. Biomass and Bioenergy, 35(7), 3208-3217. doi:10.1016/j.biombioe.2011.04.042Yu, X., Hyyppä, J., Kaartinen, H., & Maltamo, M. (2004). Automatic detection of harvested trees and determination of forest growth using airborne laser scanning. Remote Sensing of Environment, 90(4), 451-462. doi:10.1016/j.rse.2004.02.00
Software for Generating Troposphere Corrections for InSAR Using GPS and Weather Model Data
Atmospheric errors due to the troposphere are a limiting error source for spaceborne interferometric synthetic aperture radar (InSAR) imaging. This software generates tropospheric delay maps that can be used to correct atmospheric artifacts in InSAR data. The software automatically acquires all needed GPS (Global Positioning System), weather, and Digital Elevation Map data, and generates a tropospheric correction map using a novel algorithm for combining GPS and weather information while accounting for terrain. Existing JPL software was prototypical in nature, required a MATLAB license, required additional steps to acquire and ingest needed GPS and weather data, and did not account for topography in interpolation. Previous software did not achieve a level of automation suitable for integration in a Web portal. This software overcomes these issues. GPS estimates of tropospheric delay are a source of corrections that can be used to form correction maps to be applied to InSAR data, but the spacing of GPS stations is insufficient to remove short-wavelength tropospheric artifacts. This software combines interpolated GPS delay with weather model precipitable water vapor (PWV) and a digital elevation model to account for terrain, increasing the spatial resolution of the tropospheric correction maps and thus removing short wavelength tropospheric artifacts to a greater extent. It will be integrated into a Web portal request system, allowing use in a future L-band SAR Earth radar mission data system. This will be a significant contribution to its technology readiness, building on existing investments in in situ space geodetic networks, and improving timeliness, quality, and science value of the collected dat
Observation of direct-photon collective flow in sqrt(s_NN)=200 GeV Au+Au collisions
The second Fourier component v_2 of the azimuthal anisotropy with respect to
the reaction plane was measured for direct photons at midrapidity and
transverse momentum (p_T) of 1--13 GeV/c in Au+Au collisions at sqr(s_NN)=200
GeV. Previous measurements of this quantity for hadrons with p_T < 6 GeV/c
indicate that the medium behaves like a nearly perfect fluid, while for p_T > 6
GeV/c a reduced anisotropy is interpreted in terms of a path-length dependence
for parton energy loss. In this measurement with the PHENIX detector at the
Relativistic Heavy Ion Collider we find that for p_T > 4 GeV/c the anisotropy
for direct photons is consistent with zero, as expected if the dominant source
of direct photons is initial hard scattering. However, in the p_T < 4 GeV/c
region dominated by thermal photons, we find a substantial direct photon v_2
comparable to that of hadrons, whereas model calculations for thermal photons
in this kinematic region significantly underpredict the observed v_2.Comment: 384 authors, 6 pages, 3 figures, and 1 table. Submitted to Phys. Rev.
Lett. v2 has minor changes to match the submission version. Plain text data
tables for the points plotted in the figures are publicly available at
http://www.phenix.bnl.gov/phenix/WWW/info/data/ppg126_data.htm
Azimuthal anisotropy of pi^0 and eta mesons in Au+Au collisions at sqrt(s_NN)=200 GeV
The azimuthal anisotropy coefficients v_2 and v_4 of pi^0 and eta mesons are
measured in Au+Au collisions at sqrt(s_NN)=200 GeV, as a function of transverse
momentum p_T (1-14 GeV/c) and centrality. The extracted v_2 coefficients are
found to be consistent between the two meson species over the measured p_T
range. The ratio of v_4/v_2^2 for pi^0 mesons is found to be independent of p_T
for 1-9 GeV/c, implying a lack of sensitivity of the ratio to the change of
underlying physics with p_T. Furthermore, the ratio of v_4/v_2^2 is
systematically larger in central collisions, which may reflect the combined
effects of fluctuations in the initial collision geometry and finite viscosity
in the evolving medium.Comment: 384 authors, 71 institutions, 11 pages, 9 figures, and 2 tables.
Submitted to Physical Review C. Plain text data tables for the points plotted
in figures for this and previous PHENIX publications are (or will be)
publicly available at http://www.phenix.bnl.gov/papers.htm
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