405 research outputs found
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The effects of storytelling on student writing: A tool for the English language learner classroom
This thesis examines the use of storytelling as a tool to facilitate writing in English language learners. It examines specifically the effects storytelling had on the student use of expressive language, story structure and creativity in their writing. It also analyzed the enjoyment level storytelling brought to the writing experience of the student
Temperature, light and nitrate sensing coordinate Arabidopsis seed dormancy cycling resulting in winter and summer annual phenotypes
Seeds use environmental cues to sense the seasons and their surroundings to initiate the plants life cycle. Dormancy cycling underlying this process is extensively described, but the molecular mechanism is largely unknown. To address this we selected a range of representative genes from published array experiments in the laboratory and investigated their expression patterns in seeds of Arabidopsis ecotypes, having contrasting life cycles, over an annual dormancy cycle in the field. We show how mechanisms identified in the laboratory are coordinated in response to the soil environment to determine dormancy cycles that result in winter and summer annual phenotypes. Our results are consistent with a seed specific response to seasonal temperature patterns (temporal sensing) involving the gene DELAY OF GERMINATION1 (DOG1) that indicates the correct season; and concurrent temporally driven co-opted mechanisms that sense spatial signals i.e. nitrate via CBL-INTERACTING PROTEIN KINASE 23 (CIPK23) phosphorylation of the NITRATE TRANSPORTER 1 (NRT1.1) and light via PHYTOCHROME A (PHYA). In both ecotypes studied, when all three genes have low expression there is enhanced GIBBERELLIN 3 BETA-HYDROXYLASE 1 (GA3ox1) expression, exhumed seeds have the potential to germinate in the laboratory, and the initiation of seedling emergence occurs following soil disturbance (exposure to light) in the field. Unlike DOG1, expression of MOTHER of FLOWERING TIME (MFT) has an opposite thermal response in seeds of the two ecotypes indicating a role in determining their different dormancy cycling phenotypes
Is the Medium the Message?
Michael Dominick, of the Metropolitan Museum of Art, will moderate this important panel discussion. Panelists include Heather Pesanti, Albright-Knox Art Gallery, Buffalo NY, Gerald Mead, State University of New York College at Buffalo and Virginial Steel, Grounds for Sculpture, Hamilton, NJ.
An inquiry into why cast iron is used as an art medium and the mania that surrounds it. An important thread in this discussion will consider the possibility that this choice may be hindering your artistic career, and if so, how can this be rectified
Evaluating for Impact: Professional Development Educational Content Delivery Through Learning Communities
The National 4-H Council Learning Priorities team developed educational content for professional development to increase evaluation capacity and evaluation skills for 4-H educators. Extension specialists in Oregon, Vermont, and Virginia piloted Evaluating for Impact curriculum through learning communities. Lessons learned from the pilot project include the overall success of content in increasing individual participant evaluation skills, reflection on the comprehensive and academically rigorous nature of the curriculum, a need for an experienced evaluator to lead the circles, and an ability to customize the curriculum to the evaluation levels of participants
Formulation-dependent stability mechanisms affecting dissolution performance of directly compressed griseofulvin tablets
During drug product development, stability studies are used to ensure that the safety and efficacy of a product are not affected during storage. Any change in the dissolution performance of a product must be investigated, as this may indicate a change in the bioavailability. In this study, three different griseofulvin formulations were prepared containing microcrystalline cellulose (MCC) with either mannitol, lactose monohydrate, or dibasic calcium phosphate anhydrous (DCPA). The tensile strength, porosity, contact angle, disintegration time, and dissolution rate were measured after storage under five different accelerated temperature and humidity conditions for 1, 2, and 4 weeks. The dissolution rate was found to decrease after storage for all three batches, with the change in dissolution rate strongly correlating with the storage humidity. The changes in physical properties of each formulation were found to relate to either the premature swelling (MCC/DCPA, MCC/lactose) or dissolution (MCC/mannitol) of particles during storage. These results are also discussed with consideration of the performance- and stability-controlling mechanisms of placebo tablets of the same formulations [1, 2]
Tablet disintegration performance : effect of compression pressure and storage conditions on surface liquid absorption and swelling kinetics
The disintegration process of pharmaceutical tablets is a crucial step in the oral delivery of a drug. Tablet disintegration does not only refer to the break up of the interparticle bonds, but also relates to the liquid absorption and swelling behaviour of the tablet. This study demonstrates the use of the sessile drop method coupled with image processing and models to analyse the surface liquid absorption and swelling kinetics of four filler combinations (microcrystalline cellulose (MCC)/mannitol, MCC/lactose, MCC/dibasic calcium phosphate anhydrous (DCPA) and DCPA/lactose) with croscarmellose sodium as a disintegrant. Changes in the disintegration performance of these formulations were analysed by quantifying the effect of compression pressure and storage condition on characteristic liquid absorption and swelling parameters. The results indicate that the disintegration performance of the MCC/mannitol and MCC/lactose formulations are driven by the liquid absorption behaviour. For the MCC/DCPA formulation, both liquid absorption and swelling characteristics affect the disintegration time, whereas DCPA/lactose tablets is primarily controlled by swelling characteristics of the various excipients. The approach discussed in this study enables a rapid (< 1 min) assessment of characteristic properties that are related to tablet disintegration to inform the design of the formulation, process settings and storage conditions
LMDA Newsletter, July 1, 2016
Contents include: Letter from the Editor; A Message from our LMDA President; Canadian Fellows: Vicki Stroich & Bob White in Conversation; Freelancing Across America: On the Road with Heather Helinsky; From Producing to Freelancing: Artistic Leaders Jayne Wenger & Mead Hunter; Freelancing in Canada: David Geary Talks Shop & Indigenous Dramaturgy; Early Career Projects: Anna Woodruff Collaborates with Melis Aker; Benches We Have Shared: Elizabeth Bennett & Liz Engelman Talk Life after Institutional Dramaturgy; Upcoming Events.https://soundideas.pugetsound.edu/lmdanewsletter/1008/thumbnail.jp
The Grizzly, October 11, 1994
The Last Pledging Season? • Homecoming \u2794 a Success • The American Sexual Landscape • Fire, Fire! • Religious Sect Linked to Murder-Suicides • Campus Artwork Encounters Vandalism • Soup Kitchen Visit Provides Eye-Opening Experience • Retired Officer Expresses Thanks to Ursinus Community • Celebrate National Coming Out Day with GALA • Red and Gold Students Storm the Campus • Security Officer Larry Kirlin Leaves Ursinus • Memories of Homecoming 1994 • A Healthy Outlook on Life • Update From Career Planning & Placement • An Open Letter to President Richter • UC Soccer Wins in Closing Minutes • Walker Memorial Winners • Golley Wins McIntyre Award • UC Wins On Homecoming, 21-20https://digitalcommons.ursinus.edu/grizzlynews/1343/thumbnail.jp
Interventions for treating children and adolescents with overweight and obesity:An overview of Cochrane reviews
Children and adolescents with overweight and obesity are a global health concern. This is an integrative overview of six Cochrane systematic reviews, providing an up-to-date synthesis of the evidence examining interventions for the treatment of children and adolescents with overweight or obesity. The data extraction and quality assessments for each review were conducted by one author and checked by a second. The six high quality reviews provide evidence on the effectiveness of behaviour changing interventions conducted in children <6 years (7 trials), 6-11 years (70 trials), adolescents 12-17 years (44 trials) and interventions that target only parents of children aged 5-11 years (20 trials); in addition to interventions examining surgery (1 trial) and drugs (21 trials). Most of the evidence was derived from high-income countries and published in the last two decades. Collectively, the evidence suggests that multi-component behaviour changing interventions may be beneficial in achieving small reductions in body weight status in children of all ages, with low adverse event occurrence were reported. More research is required to understand which specific intervention components are most effective and in whom, and how best to maintain intervention effects. Evidence from surgical and drug interventions was too limited to make inferences about use and safety, and adverse events were a serious consideration
The Grizzly, September 29, 1992
Yes, Mom, I Really Do Live Here: Parents Day 1992 • APO and Demas Honored • Taking Time to Talk with New Faculty • How Ursinus Rates • International Wednesday • Literature? At Ursinus? • Spotlight: Milo Winter • Nothing to Do? Then Make Something Happen! • An Alternative to Litigation • Letters to the Editor • An Educated Vote • The Cross-Country Steamroller • Sports Week in Reviewhttps://digitalcommons.ursinus.edu/grizzlynews/1299/thumbnail.jp
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