867 research outputs found
Compiling Linguistic Constraints into Finite State Automata
International audienceThis paper deals with linguistic constraints encoded in the form of (binary) tables, generally called lexicon-grammar tables. We describe a unified method to compile sets of tables of linguistic constraints into Finite State Automata. This method has been practically implemented in the linguistic platform Unitex
A conceptual exoskeleton shoulder design for the assistance of upper limb movement
© Springer International Publishing AG, part of Springer Nature 2018. There is an increased interest on wearable technologies for rehabilitation and human augmentation. Systems focusing on the upper limbs are attempting to replicate the musculoskeletal structures found in humans, reproducing existing behaviors and capabilities. The current work is expanding on existing systems with a novel design that ensures the maximum range of motion while at the same time allowing for lockable features ensuring higher manipulation payloads at minimum energy and fatigue costs. An analysis of the biomechanics of the shoulder is being done and a detailed system design for structural as well actuation elements of a parallel mechanism is given. The benefits for the use are discussed of reduced weight, maximum range of motion at minimum energy cost
PIONIER: a visitor instrument for the VLTI
PIONIER is a 4-telescope visitor instrument for the VLTI, planned to see its
first fringes in 2010. It combines four ATs or four UTs using a pairwise ABCD
integrated optics combiner that can also be used in scanning mode. It provides
low spectral resolution in H and K band. PIONIER is designed for imaging with a
specific emphasis on fast fringe recording to allow closure-phases and
visibilities to be precisely measured. In this work we provide the detailed
description of the instrument and present its updated status.Comment: Proceedings of SPIE conference Optical and Infrared Interferometry II
(Conference 7734) San Diego 201
WISP-2 expression induced by Teriparatide treatment affects in vitro osteoblast differentiation and improves in vivo osteogenesis
The Osteocyte, recognized as a major orchestrator of osteoblast and osteoclast activity, is the most important key player during bone remodeling processes. Imbalances occurring during bone remodeling, caused by hormone perturbations or by mechanical loading alterations, can induce bone pathologies such as osteoporosis. Recently, the active fraction of parathormone, PTH (1-34) or Teriparatide (TPTD), was chosen as election treatment for osteoporosis. The effect of such therapy is dependent on the temporal manner of administration. The molecular reasons why the type of administration regimen is so critical for the fate of bone remodeling are numerous and not yet well known. Our study attempts to analyze diverse signaling pathways directly activated in osteocytes upon TPTD treatment. By means of gene array analysis, we found many molecules upregulated or downregulated in osteocytes. Later, we paid attention to Wisp-2, a protein involved in the Wnt pathway, that is secreted by MLO-Y4 cells and increases upon TPTD treatment and that is able to positively influence the early phases of osteogenic differentiation. We also confirmed the pro osteogenic property of Wisp-2 during mesenchymal stem cell differentiation into the preliminary osteoblast phenotype. The same results were confirmed with an in vivo approach confirming a remarkable Wisp-2 expression in metaphyseal trabecular bone. These results highlighted the anabolic roles unrolled by osteocytes in controlling the action of neighboring cells, suggesting that the perturbation of certain signaling cascades, such as the Wnt pathway, is crucial for the positive regulation of bone formation
SPHERE: the exoplanet imager for the Very Large Telescope
Observations of circumstellar environments to look for the direct signal of
exoplanets and the scattered light from disks has significant instrumental
implications. In the past 15 years, major developments in adaptive optics,
coronagraphy, optical manufacturing, wavefront sensing and data processing,
together with a consistent global system analysis have enabled a new generation
of high-contrast imagers and spectrographs on large ground-based telescopes
with much better performance. One of the most productive is the
Spectro-Polarimetic High contrast imager for Exoplanets REsearch (SPHERE)
designed and built for the ESO Very Large Telescope (VLT) in Chile. SPHERE
includes an extreme adaptive optics system, a highly stable common path
interface, several types of coronagraphs and three science instruments. Two of
them, the Integral Field Spectrograph (IFS) and the Infra-Red Dual-band Imager
and Spectrograph (IRDIS), are designed to efficiently cover the near-infrared
(NIR) range in a single observation for efficient young planet search. The
third one, ZIMPOL, is designed for visible (VIR) polarimetric observation to
look for the reflected light of exoplanets and the light scattered by debris
disks. This suite of three science instruments enables to study circumstellar
environments at unprecedented angular resolution both in the visible and the
near-infrared. In this work, we present the complete instrument and its on-sky
performance after 4 years of operations at the VLT.Comment: Final version accepted for publication in A&
Post conjunction detection of Pictoris b with VLT/SPHERE
With an orbital distance comparable to that of Saturn in the solar system,
\bpic b is the closest (semi-major axis \,9\,au) exoplanet that has
been imaged to orbit a star. Thus it offers unique opportunities for detailed
studies of its orbital, physical, and atmospheric properties, and of
disk-planet interactions. With the exception of the discovery observations in
2003 with NaCo at the Very Large Telescope (VLT), all following astrometric
measurements relative to \bpic have been obtained in the southwestern part of
the orbit, which severely limits the determination of the planet's orbital
parameters. We aimed at further constraining \bpic b orbital properties using
more data, and, in particular, data taken in the northeastern part of the
orbit.
We used SPHERE at the VLT to precisely monitor the orbital motion of beta
\bpic b since first light of the instrument in 2014. We were able to monitor
the planet until November 2016, when its angular separation became too small
(125 mas, i.e., 1.6\,au) and prevented further detection. We redetected \bpic b
on the northeast side of the disk at a separation of 139\,mas and a PA of
30 in September 2018. The planetary orbit is now well constrained.
With a semi-major axis (sma) of au (1 ), it
definitely excludes previously reported possible long orbital periods, and
excludes \bpic b as the origin of photometric variations that took place in
1981. We also refine the eccentricity and inclination of the planet. From an
instrumental point of view, these data demonstrate that it is possible to
detect, if they exist, young massive Jupiters that orbit at less than 2 au from
a star that is 20 pc away.Comment: accepted by A&
Highlights from the Pierre Auger Observatory
The Pierre Auger Observatory is the world's largest cosmic ray observatory.
Our current exposure reaches nearly 40,000 km str and provides us with an
unprecedented quality data set. The performance and stability of the detectors
and their enhancements are described. Data analyses have led to a number of
major breakthroughs. Among these we discuss the energy spectrum and the
searches for large-scale anisotropies. We present analyses of our X
data and show how it can be interpreted in terms of mass composition. We also
describe some new analyses that extract mass sensitive parameters from the 100%
duty cycle SD data. A coherent interpretation of all these recent results opens
new directions. The consequences regarding the cosmic ray composition and the
properties of UHECR sources are briefly discussed.Comment: 9 pages, 12 figures, talk given at the 33rd International Cosmic Ray
Conference, Rio de Janeiro 201
The density-matrix renormalization group
The density-matrix renormalization group (DMRG) is a numerical algorithm for
the efficient truncation of the Hilbert space of low-dimensional strongly
correlated quantum systems based on a rather general decimation prescription.
This algorithm has achieved unprecedented precision in the description of
one-dimensional quantum systems. It has therefore quickly acquired the status
of method of choice for numerical studies of one-dimensional quantum systems.
Its applications to the calculation of static, dynamic and thermodynamic
quantities in such systems are reviewed. The potential of DMRG applications in
the fields of two-dimensional quantum systems, quantum chemistry,
three-dimensional small grains, nuclear physics, equilibrium and
non-equilibrium statistical physics, and time-dependent phenomena is discussed.
This review also considers the theoretical foundations of the method, examining
its relationship to matrix-product states and the quantum information content
of the density matrices generated by DMRG.Comment: accepted by Rev. Mod. Phys. in July 2004; scheduled to appear in the
January 2005 issu
Reconstruction of inclined air showers detected with the Pierre Auger Observatory
We describe the method devised to reconstruct inclined cosmic-ray air showers
with zenith angles greater than detected with the surface array of
the Pierre Auger Observatory. The measured signals at the ground level are
fitted to muon density distributions predicted with atmospheric cascade models
to obtain the relative shower size as an overall normalization parameter. The
method is evaluated using simulated showers to test its performance. The energy
of the cosmic rays is calibrated using a sub-sample of events reconstructed
with both the fluorescence and surface array techniques. The reconstruction
method described here provides the basis of complementary analyses including an
independent measurement of the energy spectrum of ultra-high energy cosmic rays
using very inclined events collected by the Pierre Auger Observatory.Comment: 27 pages, 19 figures, accepted for publication in Journal of
Cosmology and Astroparticle Physics (JCAP
A search for point sources of EeV photons
Measurements of air showers made using the hybrid technique developed with
the fluorescence and surface detectors of the Pierre Auger Observatory allow a
sensitive search for point sources of EeV photons anywhere in the exposed sky.
A multivariate analysis reduces the background of hadronic cosmic rays. The
search is sensitive to a declination band from -85{\deg} to +20{\deg}, in an
energy range from 10^17.3 eV to 10^18.5 eV. No photon point source has been
detected. An upper limit on the photon flux has been derived for every
direction. The mean value of the energy flux limit that results from this,
assuming a photon spectral index of -2, is 0.06 eV cm^-2 s^-1, and no celestial
direction exceeds 0.25 eV cm^-2 s^-1. These upper limits constrain scenarios in
which EeV cosmic ray protons are emitted by non-transient sources in the
Galaxy.Comment: 28 pages, 10 figures, accepted for publication in The Astrophysical
Journa
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