110 research outputs found

    The Effectiveness of the NFL’s Rooney Rule

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    The Rooney Rule in the NFL was created in order to create an atmosphere of racial equality and fairness when relating to hiring practices. The general consensus on the Rooney Rule is that it has been successful so far, but there is still a lot to do in order to counteract racial bias when it comes to hiring employees. After nine years of validation, it is still yet to be seen if the Rooney Rule has made changes to the NFL. This research explores the positions of Offensive Coordinator, Defensive Coordinator, and General Manager in all 32 NFL franchises to determine if the implementation of the Rooney Rule has impacted the racial diversity of those holding the positions. The effectiveness of the Rooney Rule can is measured by not only the impact that the rule has had on positions that require an interview for minority candidates, but also the “trickledown” effect for those positions that do not require a minority candidate interview for a vacancy. Aspects of racism, reverse racism, and Title VII are used to contextualize the findings. Of the positions that were analyzed, only General Manager showed a significant increase in minority held positions

    Evaluation of the long term impacts of an infiltration BMP

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    Proceedings of the Seventh International Conference on Hydroscience and Engineering, Philadelphia, PA, September 2006. http://hdl.handle.net/1860/732The natural hydrologic cycle is severely disrupted by development because the water that used to infiltrate into the ground is now running off into nearby streams. The negative impact of development on streams includes increased stream bank erosion, pollutant levels, and decreased base flow. Best management practices (BMPs) are recommended by regulatory agencies because they can mitigate peak flow, provide treatment, and partially restore the natural hydrologic cycle. BMP is a broad term used to describe a host of structures and activities; they are classified as structural (e.g. infiltration basin) or non structural (e.g. street cleaning). While infiltration BMPs are gaining acceptance, there is a concern that infiltrating stormwater has solved one problem by improving stream quality, but has caused another by contaminating the groundwater. To date, there have not been many opportunities to study the long term effects of infiltration. However, two 85 to 100 year old infiltration pits were discovered on the campus of Villanova University. Soil samples were collected from these pits and were tested for copper. Copper was selected based on the contaminants seen in the stormwater at other Villanova BMP sites. One of the pits has low infiltration rates and a plan to restore its infiltration capacity is described. This restored infiltration pit will serve as a permanent demonstration and research site, joining a collection of BMPs at Villanova University

    Topological representations of matroid maps

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    The Topological Representation Theorem for (oriented) matroids states that every (oriented) matroid can be realized as the intersection lattice of an arrangement of codimension one homotopy spheres on a homotopy sphere. In this paper, we use a construction of Engstr\"om to show that structure-preserving maps between matroids induce topological mappings between their representations; a result previously known only in the oriented case. Specifically, we show that weak maps induce continuous maps and that the process is a functor from the category of matroids with weak maps to the homotopy category of topological spaces. We also give a new and conceptual proof of a result regarding the Whitney numbers of the first kind of a matroid.Comment: Final version, 21 pages, 8 figures; Journal of Algebraic Combinatorics, 201

    2015 Progress Report: Design And Health Research Consortium

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    The Architects Foundation, along with the American Institute of Architects (AIA) and the Association of Collegiate Schools of Architecture (ACSA), issued this first progress report of the AIA's Design and Health Research Consortium. The consortium helps translate research on design's influence on public health into architectural practice for policymakers, design and public health professionals and the general public.The 2015 report covers consortium activities across a spectrum of research issues where design contributes to public health, from the effects of indoor temperatures on sleep deprivation and depression to a "best design" competition for a mobile isolation treatment unit to combat the Ebola epidemic

    The SAMI Galaxy Survey: impact of black hole activity on galaxy spin-filament alignments

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    The activity of central supermassive black holes might affect the alignment of galaxy spin axes with respect to the closest cosmic filaments. We exploit the SAMI Galaxy Survey to study possible relations between black hole activity and the spin-filament alignments of stars and ionised gas separately. To explore the impact of instantaneous black hole activity, active galaxies are selected according to emission-line diagnostics. Central stellar velocity dispersion (σc\sigma_c) is used as a proxy for black hole mass and its integrated activity. We find evidence for the gas spin-filament alignments to be influenced by AGN, with Seyfert galaxies showing a stronger perpendicular alignment at fixed bulge mass with respect to galaxies where ionisation is consequence of low-ionizaition nuclear emission-line regions (LINERs) or old stellar populations (retired galaxies). On the other hand, the greater perpendicular tendency for the stellar spin-filament alignments of high-bulge mass galaxies is dominated by retired galaxies. Stellar alignments show a stronger correlation with σc\sigma_c compared to the gas alignments. We confirm that bulge mass (MbulgeM_{bulge}) is the primary parameter of correlation for both stellar and gas spin-filament alignments (with no residual dependency left for σc\sigma_c), while σc\sigma_c is the most important property for secular star formation quenching (with no residual dependency left for MbulgeM_{bulge}). These findings indicate that MbulgeM_{bulge} and σc\sigma_c are the most predictive parameters of two different galaxy evolution processes, suggesting mergers trigger spin-filament alignment flips and integrated black hole activity drives star formation quenching.Comment: 20 pages, 16 figures, accepted for publication in MNRA

    New Peptides Isolated from Lyngbya Species: A Review

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    Cyanobacteria of the genus Lyngbya have proven to be prodigious producers of secondary metabolites. Many of these compounds are bioactive and show potential for therapeutic use. This review covers peptides and hybrid polyketide-non-ribosomal peptides isolated from Lyngbya species. The structures and bioactivities of 50 Lyngbya peptides which were reported since 2007 are presented

    Blockade of Mast Cell Activation Reduces Cutaneous Scar Formation

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    Damage to the skin initiates a cascade of well-orchestrated events that ultimately leads to repair of the wound. The inflammatory response is key to wound healing both through preventing infection and stimulating proliferation and remodeling of the skin. Mast cells within the tissue are one of the first immune cells to respond to trauma, and upon activation they release pro-inflammatory molecules to initiate recruitment of leukocytes and promote a vascular response in the tissue. Additionally, mast cells stimulate collagen synthesis by dermal fibroblasts, suggesting they may also influence scar formation. To examine the contribution of mast cells in tissue repair, we determined the effects the mast cell inhibitor, disodium cromoglycate (DSCG), on several parameters of dermal repair including, inflammation, re-epithelialization, collagen fiber organization, collagen ultrastructure, scar width and wound breaking strength. Mice treated with DSCG had significantly reduced levels of the inflammatory cytokines IL-1a, IL-1b, and CXCL1. Although DSCG treatment reduced the production of inflammatory mediators, the rate of re-epithelialization was not affected. Compared to control, inhibition of mast cell activity caused a significant decrease in scar width along with accelerated collagen re-organization. Despite the reduced scar width, DSCG treatment did not affect the breaking strength of the healed tissue. Tryptase b1 exclusively produced by mast cells was found to increase significantly in the course of wound healing. However, DSCG treatment did not change its level in the wounds. These results indicate that blockade of mast cell activation reduces scar formation and inflammation without further weakening the healed wound

    A late Middle Pleistocene Denisovan mandible from the Tibetan Plateau

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    Denisovans are members of a hominin group who are currently only known directly from fragmentary fossils, the genomes of which have been studied from a single site, Denisova Cave in Siberia. They are also known indirectly from their genetic legacy through gene flow into several low-altitude East Asian populations and high-altitude modern Tibetans6. The lack of morphologically informative Denisovan fossils hinders our ability to connect geographically and temporally dispersed fossil hominins from Asia and to understand in a coherent manner their relation to recent Asian populations. This includes understanding the genetic adaptation of humans to the high-altitude Tibetan Plateau, which was inherited from the Denisovans. Here we report a Denisovan mandible, identified by ancient protein analysis, found on the Tibetan Plateau in Baishiya Karst Cave, Xiahe, Gansu, China. We determine the mandible to be at least 160 thousand years old through U-series dating of an adhering carbonate matrix. The Xiahe specimen provides direct evidence of the Denisovans outside the Altai Mountains and its analysis unique insights into Denisovan mandibular and dental morphology. Our results indicate that archaic hominins occupied the Tibetan Plateau in the Middle Pleistocene epoch and successfully adapted to high-altitude hypoxic environments long before the regional arrival of modern Homo sapiens

    Digital reconstruction of the inner ear of Leptictidium auderiense (Leptictida, Mammalia) and North American leptictids reveals new insight into leptictidan locomotor agility

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    Leptictida are basal Paleocene to Oligocene eutherians from Europe and North America comprising species with highly specialized postcranial features including elongated hind limbs. Among them, the European Leptictidium was probably a bipedal runner or jumper. Because the semicircular canals of the inner ear are involved in detecting angular acceleration of the head, their morphometry can be used as a proxy to elucidate the agility in fossil mammals. Here we provide the first insight into inner ear anatomy and morphometry of Leptictida based on high-resolution computed tomography of a new specimen of Leptictidium auderiense from the middle Eocene Messel Pit (Germany) and specimens of the North American Leptictis and Palaeictops. The general morphology of the bony labyrinth reveals several plesiomorphic mammalian features, such as a secondary crus commune. Leptictidium is derived from the leptictidan groundplan in lacking the secondary bony lamina and having proportionally larger semicircular canals than the leptictids under study. Our estimations reveal that Leptictidium was a very agile animal with agility score values (4.6 and 5.5, respectively) comparable to Macroscelidea and extant bipedal saltatory placentals. Leptictis and Palaeictops have lower agility scores (3.4 to 4.1), which correspond to the more generalized types of locomotion (e.g., terrestrial, cursorial) of most extant mammals. In contrast, the angular velocity magnitude predicted from semicircular canal angles supports a conflicting pattern of agility among leptictidans, but the significance of these differences might be challenged when more is known about intraspecific variation and the pattern of semicircular canal angles in non-primate mammals

    Sensory Communication

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    Contains table of contents for Section 2 and reports on five research projects.National Institutes of Health Contract 2 R01 DC00117National Institutes of Health Contract 1 R01 DC02032National Institutes of Health Contract 2 P01 DC00361National Institutes of Health Contract N01 DC22402National Institutes of Health Grant R01-DC001001National Institutes of Health Grant R01-DC00270National Institutes of Health Grant 5 R01 DC00126National Institutes of Health Grant R29-DC00625U.S. Navy - Office of Naval Research Grant N00014-88-K-0604U.S. Navy - Office of Naval Research Grant N00014-91-J-1454U.S. Navy - Office of Naval Research Grant N00014-92-J-1814U.S. Navy - Naval Air Warfare Center Training Systems Division Contract N61339-94-C-0087U.S. Navy - Naval Air Warfare Center Training System Division Contract N61339-93-C-0055U.S. Navy - Office of Naval Research Grant N00014-93-1-1198National Aeronautics and Space Administration/Ames Research Center Grant NCC 2-77
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