An AFLP marker linked to the Pm-1 gene that confers resistance to Podosphaera xanthii race 1 in Cucumis melo

Brazil produced 330,000 metric tons of melons in 2005, principally in the Northeast region where one of the most important melon pathogens is the powdery mildew fungus Podosphaera xanthii. The disease is controlled mainly by incorporating single dominant resistance genes into commercial hybrids. We report on linkage analysis of the Pm-1 resistance gene, introgressed from the AF125Pm-1 Cantalupensis Charentais-type breeding line into the yellow-fleshed melon (Group Inodorus) breeding line AF426-S by backcrossing to produce the resistant line AF426-R, and the amplified fragment length polymorphism (AFLP) marker M75/H35_155 reported to be polymorphic between AF426-S and AF426-R. Segregation analysis of M75/H35_155 using a backcross population of 143 plants derived from [AF426-R x AF426-S] x AF426-S and screened for resistance to P. xanthii race 1 produced a recombination frequency of 4.9%, indicating close linkage between M75/H35_155 and Pm-1. Using the same segregating population, the M75/H35_155 marker had previously been reported to be distantly linked to Prv¹, a gene conferring resistance to papaya ringspot virus-type W. Since M75/H35_155 is linked to Prv¹ at a distance of 40.9 cM it is possible that Pm-1 and Prv¹ are also linked.(FAPESP) São Paulo Research Foundatio

Erratum to "Intermittent treatment of knee osteoarthritis with oral chondroitin sulfate: a one-year, randomized, double-blind, multicenter study versus placebo" [Osteoarthritis Cartilage 12 (2004) 269–276]

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Análise do perfil de mães e crianças expostas intraútero ao HIV nascidas em uma maternidade de hospital público terciário do sul do Brasil

OBJECTIVES: evaluate the profile of children exposed intrauterine to HIV born in a tertiary hospital in southern Brazil, describe the prevalence of children classified as high risk and the rate of vertical transmission in this population. METODOLOGY: cross-sectional analytical-observational study. All HIV-exposed children born in 2019 and 2020 at the Clinical Hospital of the Federal University of Paraná were included. Data were collected from the hospitals operating systems, physical records and SISCEL. Study approved by the hospital ethics committee. RESULTS: 142 patients were included. Among the mothers, 26.06% had a detectable viral load in the last trimester, of which 54.05% were above 1000 copies; 37.32% were diagnosed during pregnancy; 40% of women who were diagnosed during pregnancy had a detectable viral load in the 3rd trimester (p=0.01). Of those who had a detectable viral load in the third trimester, 88.89% used ART irregularly or did not use (p < 0.01); 44.37% of newborns were classified as high risk by the current protocol in the period, while with the current new protocol would be 63.38%. The vertical transmission rate was 1.41%. There was 42.26% of loss of follow-up. CONCLUSION: the prevalence of vertical transmission was low, comparable to developed countries. Quality prenatal care, early diagnosis and adherence to ART are factors that modify the rates of vertical transmission of HIV due to the reduction of maternal viral load in the third trimester

Cruise Summary Report - MEDWAVES survey. MEDiterranean out flow WAter and Vulnerable EcosystemS (MEDWAVES)

The MEDWAVES (MEDiterranean out flow WAter and Vulnerable EcosystemS) cruise targeted areas under the potential influence of the MOW within the Mediterranean and Atlantic realms. These include seamounts where Cold-water corals (CWCs) have been reported but that are still poorly known, and which may act as essential “stepping stones” connecting fauna of seamounts in the Mediterranean with those of the continental shelf of Portugal, the Azores and the Mid-Atlantic Ridge. During MEDWAVES sampling has been conducted in two of the case studies of ATLAS: Case study 7 (Gulf of Cádiz-Strait of Gibraltar-Alboran Sea) and Case study 8 (Azores). The initially targeted areas in the Atlantic were: the Gazul Mud volcano, in the Gulf of Cádiz (GoC) area, included in the case study 7, and the Atlantic seamounts Ormonde (Portuguese shelf) and Formigas (by Azores), both part of the case study 8. In the Mediterranean the targeted areas were The Guadiaro submarine canyon and the Seco de los Olivos (also known as Chella Bank) seamount. Unfortunately it was not possible to sample in Guadiaro due to time constraints originated by adverse meteorological conditions which obligate us to reduce the time at sea focusing only in 4 of the 5 initially planned areas. MEDWAVES was structured in two legs; the first leg took place from the 21st September (departure from Cádiz harbour in Spain) to the 13th October 2016 (arrival in Ponta Delgada, São Miguel, Azores, Portugal took place the 8th of October due to the meteorological conditions that obligated to conclude the first leg earlier as planned). during the Leg 1 sampling was carried out in Gazul, Ormonde and Formigas. The second leg started the 14th October (departure from Ponta Delgada) and finished the 26th October (arrival in Málaga harbour, Spain). MEDWAVES had a total of 30 effective sampling days, being 6 days not operative due to the adverse meteorological conditions experienced during the first leg which forced us to stay in Ponta Delgada from the 08th to the 13th October. During MEDWAVES the daily routine followed a similar scheme, depending of course on the weather and sea conditions. The main activity during the day, starting early in the morning (around 08:00 AM, once the night activities were finished), was the ROV deployment. Generally a single ROV dive of around 8 hours was performed, however in several occasions two dives were carried out in the same day (see General station list, Appendix II). After the ROV (and sometimes between two dives) the Box Corer and/or Van Veen Grab and/or Multicore was deployed. After these activities, during the night CTD-Rosette deployments and MB was conducted. Accordingly to this schema the scientific personnel worked in the day or in the night watch. A total of 215 sampling stations have been covered in MEDWAVES, using the following sampling gears: Multibeam echosounder, CTD-Rosette, LADCP, Box Corer, Van Veen Grab, Multicorer and a Remotely Operated Vehicle (ROV). Table 1 sumamrised the number of sampling stations conducted with each gear in each sampling zone. Additionally MB surveys have been conducted during the transits between area

A EXIGÊNCIA DO ESTUDO DE IMPACTO DE VIZINHANÇA COMO FERRAMENTA DE DEMOCRACIA E FUNÇÃO SOCIAL DA PROPRIEDADE

O adensamento populacional com o crescimento das cidades traz progressivos conflitos de ordem urbano-ambiental nos centros urbanos e com isso novos desafios aos ramos do Direito Urbanístico e Ambiental. O presente artigo propõe evidenciar a importância do Estudo de Impacto de Vizinhança (EIV), previsto na Lei Federal n. 10.257/2001, denominada Estatuto da Cidade, em vista dos Princípios da Gestão Democrática das Cidades, da Justiça Social e da Função Social da Propriedade. Além disso, busca-se investigar a possibilidade de se exigir o referido Estudo mesmo quando da omissão legislativa municipal em regulamentar os critérios do EIV. A importância da temática advém do caráter difuso do direito à cidade sustentável, de modo a buscar meios de efetivar os direitos fundamentais expressos na Constituição Federal de 1988, como o direito ao meio ambiente natural e urbano e os outros correspondentes à dignidade da pessoa humana, às presentes e futuras gerações.PALAVRAS-CHAVE: Direito Urbanístico; Estudo de Impacto de Vizinhança; Exigibilidade.ABSTRACT: The population densification with the growth of cities brings progressive conflicts of urban-environmental order in the urban centers and with this new challenges to the areas of Urban and Environmental Law. The present article proposes to highlight the importance of the Neighborhood Impact Study (EIV), foreseen in Federal Law n. 10.257/2001, called the City Statute, in view of the Principles of Democratic Management of Cities, Social Justice and the Social Function of Property. In addition, it is sought to investigate the possibility of requiring the said Study even when the municipal legislative omission to regulate the EIV criteria. The importance of this theme stems from the diffuse character of the right to a sustainable city, in order to seek ways to realize the fundamental rights expressed in the Federal Constitution of 1988, such as the right to the natural and urban environment and the others corresponding to the dignity of the human person, to present and future generations.KEYWORDS: Urbanistic Law; Neighborhood Impact Study; Requirement