Concept for an event-triggered wireless sensor network for vibration-based diagnosis in trams

Trams are the most durable and resource efficient forms of public transportation. However, because of the varying wear in dependence on their operation mode and load levels, there is a need for condition monitoring and early maintenance. Vibration sensors provide interesting possibilities to monitor the relevant tram drive components. In this contribution we investigate their use under real conditions. On the basis of cable bound vibration measurements, the influence of the crossed track section, the tram speed and the tram condition is shown. Based on the investigation results, a concept is proposed in which a meshed and wireless sensor network, event-triggered, can acquire vibration measurement data, which are suitable for the diagnosis of tram drive components. The proposed concept has the potential to operate the sensor nodes in an energy efficient way through decentralized data evaluation taking place on the sensor node

Integration of egocentric and allocentric information during memory-guided reaching to images of a natural environment

When interacting with our environment we generally make use of egocentric and allocentric object information by coding object positions relative to the observer or relative to the environment, respectively. Bayesian theories suggest that the brain integrates both sources of information optimally for perception and action. However, experimental evidence for egocentric and allocentric integration is sparse and has only been studied using abstract stimuli lacking ecological relevance. Here, we investigated the use of egocentric and allocentric information during memory-guided reaching to images of naturalistic scenes. Participants encoded a breakfast scene containing six objects on a table (local objects) and three objects in the environment (global objects). After a 2 s delay, a visual test scene reappeared for 1 s in which 1 local object was missing (= target) and of the remaining, 1, 3 or 5 local objects or one of the global objects were shifted to the left or to the right. The offset of the test scene prompted participants to reach to the target as precisely as possible. Only local objects served as potential reach targets and thus were task-relevant. When shifting objects we predicted accurate reaching if participants only used egocentric coding of object position and systematic shifts of reach endpoints if allocentric information were used for movement planning. We found that reaching movements were largely affected by allocentric shifts showing an increase in endpoint errors in the direction of object shifts with the number of local objects shifted. No effect occurred when one local or one global object was shifted. Our findings suggest that allocentric cues are indeed used by the brain for memory-guided reaching towards targets in naturalistic visual scenes. Moreover, the integration of egocentric and allocentric object information seems to depend on the extent of changes in the scene

Neonatological and pulmonological management of bilateral pulmonary sequestration in a neonate

Background: Bronchopulmonary sequestration is a lung malformation characterized by nonfunctioning lung tissue without primary communication with the tracheobronchial tree. Intrauterine complications such as mediastinal shift, pleural effusion or fetal hydrothorax can be present. We present the case of a newborn with bilateral intralobar pulmonary sequestration. Methods: Prenatal ultrasonography in a primigravida at 20 weeks of gestation revealed echogenic masses in the right fetal hemithorax with mediastinal shift towards the left side. Serial ultrasound confirmed persistence of the lesion with otherwise appropriate fetal development. Delivery was uneventful and physical examination revealed an isolated intermittent tachypnea. Chest CT scan and CT angiography showed a bilateral intrathoracic lesion with arterial supply from the aorta. Baby lung function testing suggested possible multiple functional compartments. Results: Right and left thoracotomy was performed at the age of 7 months. A bilateral intralobar sequestration with vascularisation from the aorta was resected. Pathological and histological examination of the resected tissue confirmed the surgical diagnosis. At the age of 24 months, the child was doing well without pulmonary complications. Conclusions: Bilateral pulmonary sequestration requires intensive prenatal and postnatal surveillance. Though given the fact of a bilateral pulmonary sequestration, postnatal outcome showed similar favourable characteristics to an unilateral presentation. Baby lung function testing could provide additional information for optimal postnatal management and timing of surgical interventio

Enhancing Flow Batteries: Topology Optimization of Electrode Porosity and Shape Optimization of Cell Design

This research focuses on the improvement of porosity distribution within the electrode of an all-vanadium redox flow battery (VRFB) and on optimizing novel cell designs. A half-cell model, coupled with topology and shape optimization framework, is introduced. The multiobjective functional in both cases aims to minimize pressure drop while maximizing reaction rate within the cell. Topology optimization results reveal dependencies on initial value, porosity constraint, and flow rate. The distribution with lower porosity is preferred downstream of the inlet manifold. This design enhances active surface area, thus facilitating more effective conversion of incoming educts and improving mass transport of products. Compared to homogeneous electrodes, two-part design demonstrates superior performance at specific porosity values. For combined porosities of 0.7 and 0.95, optimized distribution results in 81 % reduction in pressure drop, while conversion rate decreases by 7%. As regards various cell designs, optimization suggests a need to reconsider the vertical format of a rectangular cell. Horizontal cells are favored for nearly all porosities and flow rates. Trapezoidal and radial designs characterized by reduced downstream cross sections lead to higher pressure drops and are not preferred. This work provides further valuable insight into optimizing VRFB electrodes and challenges conventional cell design assumptions

Grundlagen der Suchtechnologie

Nach einem kurzen historischen Abriss (vom ersten Register, über die ersten Idee einer Suchmaschine bis zu Google) wird die Vorgehensweise bei der automatischen Indexierung von Dokumenten vorgestellt. Wie gelangt ein Dokument in den Index und wie und welcher Reihenfolge (Ranking) wird es wieder ausgegeben. Anschließend werden die verschiedenen Suchtechnologie-Arten (Zeichenabgleichung, Reguläre Ausdrücke, Fuzzy-Suche, Phonetische Suche, Semantische Suche) und Ranking-Verfahren (Formale Sortierung, On-Page-Faktoren, On-Site-Faktoren, Link-Faktoren, Eigenschaften und Verhalten der Nutzer) vorgestellt. Zum Abschluss wird ein kurzer Ausblick auf Suchmaschinenoptimierung gegeben

Concurrently Secure Blind Schnorr Signatures

Many applications of blind signatures (notably in blockchains) require the resulting signatures to be compatible with the existing system. This makes schemes that produce Schnorr signatures (now being standardized and supported by major cryptocurrencies like Bitcoin) desirable. Unfortunately, the existing blind-signing protocol has been shown insecure when users can open signing sessions concurrently (Eurocrypt\u2721). On the other hand, only allowing sequential sessions opens the door to denial-of-service attacks. We present the first practical, concurrently secure blind-signing protocol for Schnorr signatures, using the standard primitives NIZK and PKE and assuming that Schnorr signatures themselves are unforgeable. We cast our scheme as a generalization of blind and partially blind signatures: we introduce the notion of predicate blind signatures, in which the signer can define a predicate that the blindly signed message must satisfy. We provide proof-of-concept implementations and benchmarks for various choices of primitives and scenarios, including blindly signing Bitcoin transactions conditioned on certain properties

Grundlagen der Suchtechnologie

Nach einem kurzen historischen Abriss (vom ersten Register, über die ersten Idee einer Suchmaschine bis zu Google) wird die Vorgehensweise bei der automatischen Indexierung von Dokumenten vorgestellt. Wie gelangt ein Dokument in den Index und wie und welcher Reihenfolge (Ranking) wird es wieder ausgegeben. Anschließend werden die verschiedenen Suchtechnologie-Arten (Zeichenabgleichung, Reguläre Ausdrücke, Fuzzy-Suche, Phonetische Suche, Semantische Suche) und Ranking-Verfahren (Formale Sortierung, On-Page-Faktoren, On-Site-Faktoren, Link-Faktoren, Eigenschaften und Verhalten der Nutzer) vorgestellt. Zum Abschluss wird ein kurzer Ausblick auf Suchmaschinenoptimierung gegeben

Highly Sensitive Detection of the Antibiotic Ciprofloxacin by Means of Fiber Enhanced Raman Spectroscopy

Sepsis and septic shock exhibit a rapid course and a high fatality rate. Antibiotic treatment is time-critical and precise knowledge of the antibiotic concentration during the patients’ treatment would allow individual dose adaption. Over- and underdosing will increase the antimicrobial efficacy and reduce toxicity. We demonstrated that fiber enhanced Raman spectroscopy (FERS) can be used to detect very low concentrations of ciprofloxacin in clinically relevant doses, down to 1.5 µM. Fiber enhancement was achieved in bandgap shifted photonic crystal fibers. The high linearity between the Raman signals and the drug concentrations allows a robust calibration for drug quantification. The needed sample volume was very low (0.58 µL) and an acquisition time of 30 s allowed the rapid monitoring of ciprofloxacin levels in a less invasive way than conventional techniques. These results demonstrate that FERS has a high potential for clinical in-situ monitoring of ciprofloxacin levels

Comparison of the Effects of Early Pregnancy with Human Interferon, Alpha 2 (IFNA2), on Gene Expression in Bovine Endometrium

Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. To elucidate specific effects of bovine IFNT and of other conceptus-derived factors, endometrial gene expression changes during early pregnancy were compared to gene expression changes after intrauterine application of human IFNA2. In experiment 1, endometrial tissue samples were obtained on Day (D) 12, D15, and D18 postmating from nonpregnant or pregnant heifers. In experiment 2, heifers were treated from D14 to D16 of the estrous cycle with an intrauterine device releasing IFNA2 or, as controls, placebo lipid extrudates or PBS only. Endometrial biopsies were performed after flushing the uterus. All samples from both experiments were analyzed with an Affymetrix Bovine Genome Array. Experiment 1 revealed differential gene expression between pregnant and nonpregnant endometria on D15 and D18. In experiment 2, IFNA2 treatment resulted in differential gene expression in the bovine endometrium. Comparison of the data sets from both studies identified genes that were differentially expressed in response to IFNA2 but not in response to pregnancy on D15 or D18. In addition, genes were found that were differentially expressed during pregnancy but not after IFNA2 treatment. In experiment 3, spatiotemporal alterations in expression of selected genes were determined in uteri from nonpregnant and early pregnant heifers using in situ hybridization. The overall findings of this study suggest differential effects of bovine IFNT compared to human IFNA2 and that some pregnancy-specific changes in the endometrium are elicited by conceptus-derived factors other than IFNT