11 research outputs found
Home enteral nutrition in childrenâ2010 nationwide survey of the polish society for clinical nutrition of children
Published epidemiologic data on the administration rates of enteral/parenteral home nutrition is very limited. The aim of this first nationwide study was to assess the availability of pediatric home enteral nutrition (HEN) services in Poland. The questionnaire was sent to all regional centers providing pediatric HEN services in Poland (nâ=â14). The analysis included the number of pediatric patients who received HEN in 2010, their demographic characteristics and geographical distribution. Furthermore, the distributions of indications and methods of enteral nutrition administration were analyzed, along with the reasons of withdrawal from the HEN program. The number and fraction of children receiving HEN increased in 2010, from 433 (11.34 per 1 million inhabitants) on January 1st to 525 (13.75) on December 31st. Marked differences were observed in geographical distribution of this parameter, from zero to up to 30 pediatric patients per 1 million inhabitants. Median age of patients was 6Â years (range: 9Â monthsâ18Â years). In most cases, HEN was prescribed due to neurological disorders (nâ=â337, 64.2%), and administered by means of gastrostomy (nâ=â450, 85.71%). This study revealed the dynamic development of pediatric HEN services in Poland but also documented their potential regional shortages
Measures of body habitus are associated with lung function in adults with cystic fibrosis: a population-based study
Background
Body habitus differences may explain some of the variation in lung function between individuals with cystic fibrosis (CF). We tested the hypothesis that measures of lean muscle mass and obesity are independently associated with lung function in CF.
Methods
Cross-sectional study design using UK CF registry data from 2096 clinically stable adults.
Results
Serum creatinine and BMI were positively and independently associated with FEV1 and FVC. One standard deviation increment in serum creatinine was associated with an FEV1 increase of 171 ml (95% confidence intervals CI: + 116 to + 227 ml) in males and 90 ml (95% CI: + 46 to + 133 ml) in females. Compared to the reference group of 20â24.9 kg/m2, those with a BMI < 20 kg/m2 had lower FEV1 with values of â 642 ml (95%CI: â 784 to â 500 ml) for males and â 468 ml (95%CI: â 564 to â 372 ml) for females.
Conclusions
Prospective studies and controlled trials are required to ascertain if these associations have therapeutic potential in modifying disease progression