Beacon in the Dark

Setting the Stage for Sr. Mary Mark\u27s Memoir Beacon in the Dark, Kathleen M. Washy Beacon in the Dark, Mary Mark Mull CS

Lithofacies of the Pliocene-Pleistocene Lucayan Limestone, Great Abaco Island, Little Bahama Bank

Petrographic and sedimentologic analyses of eleven shallow subsurface cores (3 to 19 meters in length) from the Lucayan Limestone where it occurs along northeastern Great Abaco Island (little Bahama Bank) are used to delineate five carbonate lithofacies. The most prevalent lithofacies is a mottled, nonskeletal, peloidal packstone to grainstone. Other lithofacies include a rudstone, a laminated nonskeletal grainstone, a crossbedded grainstone and a mudstone-wackestone. Cementation varies from poor to very well cemented core intervals. Cements observed included equant granular, equant blocky, drusy, meniscus, and needle fiber whisker cements. These cements reflect a variety of diagenetic environments such as the vadose, meteoric, and phreatic zones. It is not possible to use the cement types to define past sea level positions. However, the cement types indicate periods of subaerial exposure that may have been a result of sea level fluctuations. The near surface carbonates of northeastern Great Abaco Island can be correlated with the upper Lucayan Limestone found on Little Bahama Bank, northwestern Great Bahama Bank and in the southeastern Bahama

Beacon in the Dark, Part 2

Beacon in the Dark Part 2, Mary Mark Mullen CSJFlying Tigers, ‘Warphans,’ Homeward Bound: Historical Background for Sister Mary Mark’s Beacon in the Dark, Part 2, Kathleen M. Wash

Afterwards

https://digitalcommons.library.umaine.edu/mmb-vp/3930/thumbnail.jp

The Experience of Ethical Dilemmas, Burnout, and Stress Among Practicing Counselors

The authors reported findings from a correlational investigation examining the relationship between counselors \u27 (N = 140) experiences with ethical dilemmas and their reported levels of burnout and stress. Using structural equation modeling, the authors identified that a higher rate of encountering ethical dilemmas related to an increased level of counselor burnout and stress among the participants. However, higher rates of reflecting on the ethical dilemmas did not have a relationship with participants\u27 burnout and stress. The authors present implications of these findings for counselors, along with future research directions

Polymerization-incompetent uromodulin in the pregnant stroke-prone spontaneously hypertensive rat

The kidney is centrally involved in blood pressure regulation and undergoes extensive changes during pregnancy. Hypertension during pregnancy may result in an altered urinary peptidome that could be used to indicate new targets of therapeutic or diagnostic interest. The stroke-prone spontaneously hypertensive rat (SHRSP) is a model of maternal chronic hypertension. Capillary electrophoresis-mass spectrometry was conducted to interrogate the urinary peptidome in SHRSP and the control Wistar–Kyoto strain at three time points: prepregnancy and gestational days 12 and 18. The comparison within and between the Wistar–Kyoto and SHRSP peptidome at all time points detected 123 differentially expressed peptides (fold change >1.5; P<0.05). Sequencing of these peptides identified fragments of collagen α-chains, albumin, prothrombin, actin, serpin A3K, proepidermal growth factor, and uromodulin. Uromodulin peptides showed a pregnancy-specific alteration in SHRSP with a 7.8-fold (P<0.01) and 8.8-fold (P<0.05) increase at gestational days 12 and 18, respectively, relative to the Wistar–Kyoto. Further investigation revealed that these peptides belonged to the polymerization-inhibitory region of uromodulin. Two forms of uromodulin (polymerization competent and polymerization incompetent) were found in urine from both Wistar–Kyoto and SHRSP, where the polymerizationincompetent form was increased in a pregnancy-specific manner in SHRSP. Nifedipine-treated pregnant SHRSP showed only polymerization-competent uromodulin, indicating that calcium may be mechanistically involved in uromodulin polymerization. This study highlights, for the first time, a potential role of uromodulin and its polymerization in hypertensive pregnancy

Induced hyperlipaemia and immune challenge in locusts

Injections of immunogens, such as β-1,3-glucan or lipopolysaccharide (LPS), bring about a marked hyperlipaemia with associated changes in lipophorins and apolipophorin-III in the haemolymph of Locusta migratoria. These changes are similar to those observed after injection of adipokinetic hormone (AKH). The possibility that endogenous AKH is released as part of the response to these immunogens is investigated using passive immunisation against AKH-I, and measurement of AKH-I titre in the haemolymph after injection of immunogens. The data presented show that, despite the similarity of the changes brought about by the presence of immunogens in the haemolymph to those brought about by AKH, there is no release of endogenous AKH after injection of laminarin or LPS. A direct effect of the immunogens on release of neutral lipids by the fat body cannot be demonstrated in vitro, and the mechanism by which hyperlipaemia is induced during immune challenge remains uncertain