Vertex importance extension of betweenness centrality algorithm

Variety of real-life structures can be simplified by a graph. Such simplification emphasizes the structure represented by vertices connected via edges. A common method for the analysis of the vertices importance in a network is betweenness centrality. The centrality is computed using the information about the shortest paths that exist in a graph. This approach puts the importance on the edges that connect the vertices. However, not all vertices are equal. Some of them might be more important than others or have more significant influence on the behavior of the network. Therefore, we introduce the modification of the betweenness centrality algorithm that takes into account the vertex importance. This approach allows the further refinement of the betweenness centrality score to fulfill the needs of the network better. We show this idea on an example of the real traffic network. We test the performance of the algorithm on the traffic network data from the city of Bratislava, Slovakia to prove that the inclusion of the modification does not hinder the original algorithm much. We also provide a visualization of the traffic network of the city of Ostrava, the Czech Republic to show the effect of the vertex importance adjustment. The algorithm was parallelized by MPI (http://www.mpi-forum.org/) and was tested on the supercomputer Salomon (https://docs.it4i.cz/) at IT4Innovations National Supercomputing Center, the Czech Republic.808726

Real time traffic simulator for self-adaptive navigation system validation

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Inbreeding and osteoporosis in Croatian island isolates

The aim of this study was to investigate a recessive genetic component in susceptibility to osteoporosis (OP) by comparing its prevalence in isolated villages of three Croatian islands: Brač, Hvar and Korčula with different levels of inbreeding. A random sample of 20-30% adults from 14 villages was obtained, including a total of 1, 389 examinees. The average inbreeding coefficient (F) of examinees from each village population was estimated using Wright's path method (based on genealogical information), isonymy data and average deviation from Hardy-Weinberg expectations for classic set of serogenetic polymorphisms. The variation in environmental, cultural and socio-economic factors between villages was investigated and shown to be minimal. The morphometry of the metacarpal bones was performed on hand-wrist radiographs of both hands in all examinees. OP was defined as values of cortical index smaller than 2 standard deviations based on distribution of values in examinees of the same sex under 45 years of age. Mean values of cortical index (CI) and prevalence of OP (both standardized by age and weighted for the sample size) in each village were correlated to the mean inbreeding coefficient (F). The coefficient of correlation (r) between F values and CI was -0.28 in males (p=0.08) and -0.42 in females (p=0.005), and between F and OP prevalence 0.32 in males (p<0.001) and 0.43 in females (p<0.001). These results indicate a trend of increased susceptibility to osteoporosis with increasing level of inbreeding in isolated communities of Croatian islands

Slike poratnog Zadra

Prikaz izložbe: Zadar. Poslijeratna urbanističko-arhitektonska obnova, 1944.-1958., Kneževa palača Zadar, 27. travnja–6. lipnja 2017.; autori izložbe Antonija Mlikota, Dubravka Kisić, Nevena Štokić, Denis Martinovi

Izolacija i karakterizacija bakterijske flore iz autohtonih fermentisanih proizvoda Srbije i Crne Gore

The natural community of lactic acid bacteria isolated from farmhouse fermented milk products has been investigated. In such products, where no starters are added, fermentation occurs as a result of natural flora present in the surrounding environment. A total of 200 isolated strains were examined for their acidification activity and EPS formation. Out of the 200 isolated strains, 27 strains were selected for further investigation. They were further identified by 16S rRNA sequencing in order to obtain the identification at species level, which showed that 14 strains belong to Lactococcus lactis subsp. lactis, 10 of them to Lactobacillus sp and 3 strains belongs to Leuconostoc sp. To differentiate between strains the pulsed-field gel electrophoresis (PFGE) patterns, of 15 isolated lactococcal strains, was generated using Smal or Ascl. Unrelated strains yielded different patterns of digestion products. The plasmid isolation of these strains has also been conducted in order to compare these results to patterns of PFGE. Phage typing of the Lactococcus sp. strains has been conducted. All lactococcal strains were resistant against 41 phages (Chr. Hansen phage collection) representing the major phage groups known for Lactococcus. These results indicate that the strains represent a possible tool for cultures that have not been exposed to any industrial selection.U ovom radu su proučavani sojevi bakterija mlečne kiseline izolovani iz autohtonih fermentisanih mlečnih proizvoda. Kod ovih proizvoda, kojima se ne dodaju starter kulture, fermentacija se odigrava kao rezultat aktivnosti prirodne mikroflore koja je prisutna u okolnoj sredini. Kod ukupno 200 sojeva proučavana je njihova sposobnost acidifikacije i sposobnost stvaranja egzopolisaharida (EPS). Od ukupno 200 izolovanih sojeva selektovano je njih 27 koji su podvrgnuti daljem proučavanju. Nakon ove selekcije, sojevi su identifikovani 16S rRNA sekvenciranjem u cilju njihove identifikacije na nivou vrste. Od 27 selektovanih sojeva, 14 je pripadalo vrsti Lactococcus lactis subsp. Lactis, 3 soja je pripadalo vrsti Leuconostoc spp., dok je 10 sojeva pripadalo vrsti Lactobacillus sp. Da bi se utvrdile razlike između različitih sojeva urađena je analiza uz korišćenje elektroforeze u pulsirajućem električnom polju (PFGE), a matrice su dobijene uz korišćenje Smal i AscI restrikcionih enzima. Sojevi koji nisu u srodstvu dali su različite matrice digestionih produkata. Izvršena je i izolacija plazmida iz ovih sojeva kako bi se potvrdili rezultati dobijeni PFGE tehnikom. Takođe je izvršena i fagotipizacija sojeva za sve sojeve za koje je dokazano da pripadaju vrsti Lactococcus sp. Svi laktokokni sojevi su bili rezistentni na 41 fag (kolekcija faga kompanije Chr. Hansen) koji predstavljaju grupu bakteriofaga koji su najčešći za vrstu Lactococcus. Dobijeni rezultati ukazuju na to da proučavani sojevi predstavljaju mogući izvor kultura koji do sada nisu bili izloženi bilo kakvoj industrijskoj selekciji

Forensic Efficiency Parameters for the 15 STR Loci in the Population of the Island of Cres (Croatia)

Forensic parameters based on 15 AmpFlSTR Identifiler short tandem repeat (STR) loci (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, VWA, TPOX, D18S51, D5S818 and FGA) were evaluated in the sample of 122 unrelated, autochthonous, adult individuals from the Island of Cres (Croatia). PCR amplification was performed with the AmpFlSTR Identifiler PCR Amplification Kit and the amplified products were separated and detected using the ABI 3130 DNA genetic analyzer. The agreement with Hardy Weinberg Equilibrium (HWE) was confirmed for all loci (p>0.05). The combined power of discrimination (PD) and the combined power of exclusion (PE) for the 15 tested STR loci were 0.99999999999999997988728679 and 0.999997397, respectively. According to the presented data, D18S51 proved to be the most informative marker followed by markers D2S1338 and D21S11. Interpopulation comparisons in allele frequencies with other East Adriatic Islands revealed significant differences for all analyzed population pairs ranging from 4 loci (Cres vs. Hvar) to 1 locus (Cres vs. Krk). Furthermore, allele frequencies comparisons of Cres and Croatian mainland revealed the lack of statistically significant differences at all studied loci. The results of the current study indicate that the examined fifteen STR loci are useful genetic markers for individual identification and paternity testing in Croatian population from the Island of Cres

Prilog flori otoka Malog Drvenika

Since there has been to date no account of the flora of the island of Mali Drvenik, we have begun floristic research that is still in progress. We have found 100 taxa of vascular plants (36 families), recorded for this island for the first time.Prigodom florističkih istraživanja na otoku Malom Drveniku pronašli smo 100 svojti vaskularnih biljaka (svrstanih u 36 porodice) koje dosad nisu bile zabilježene na ovom otoku. Floristička istraživanja se nastavljaju