Analytical prediction of reverse buckling pressure for thin shells

Analytical technique is developed for prediction of reverse buckling in thin curved shells. Test data indicate technique predicts actual reverse buckling pressure within 10 percent, and should be useful for analytical prediction of reversed condition failure for problems such as explosive decomposition through vacuum failure

Understanding Database Reconstruction Attacks on Public Data

In 2020 the U.S. Census Bureau will conduct the Constitutionally mandated decennial Census of Population and Housing. Because a census involves collecting large amounts of private data under the promise of confidentiality, traditionally statistics are published only at high levels of aggregation. Published statistical tables are vulnerable to DRAs (database reconstruction attacks), in which the underlying microdata is recovered merely by finding a set of microdata that is consistent with the published statistical tabulations. A DRA can be performed by using the tables to create a set of mathematical constraints and then solving the resulting set of simultaneous equations. This article shows how such an attack can be addressed by adding noise to the published tabulations, so that the reconstruction no longer results in the original data

Disease and psychological status in ankylosing spondylitis.

Objectives. Psychological factors may be important in the assessment and management of ankylosing spondylitis (AS). Our primary objective was to describe associations between disease and psychological status in AS, using AS-specific assessment tools and questionnaires. Our secondary objectives were to identify patient subgroups based on such associations and to determine the stability of the measures over time. Methods. A total of 110 patients were assessed at 6-monthly intervals up to four times using tools to measure disease [Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI) and the Bath Ankylosing Spondylitis Metrology Index (BASMI)], psychological [Hospital Anxiety and Depression Questionnaire (HADS), Health Locus of Control—Form C Questionnaire (HLC-C)] and generic health [Short form (SF)-36] status. Results. Eighty-nine participants completed all four assessments. Throughout the study, BASDAI, BASFI and BASMI scores correlated significantly with anxiety, depression, internality and health status, but not with levels of belief in chance or powerful others. Clinically anxious or depressed subgroups had significantly worse BASDAI and BASFI, but not BASMI, scores. BASMI scores were the least closely linked to psychological status. Mean scores for disease, psychological and health status were clinically stable over the 18 months period. Conclusions. Disease status scores in AS correlated significantly with anxiety, depression, internality and health status. Interpretation of AS disease scores should take an account of psychological status and the choice of measures used. These findings have important potential applications in AS management and monitoring, including the identification of patients for biological therapies

Cost effective use of liquid nitrogen in cryogenic wind tunnels

A method of reliquefying from 12 to 19% of the nitrogen exhaust gas from a cryogenic wind tunnel has been developed. Technical feasibility and cost effectiveness of the system depends on performance of an innovative positive displacement expander which requires scale model testing to confirm design studies. The existing cryogenic system at the 0.3-m transonic cryogenic tunnel has been surveyed and extensive upgrades proposed. Upgrades are generally cost effective and may be implemented immediately since they are based on established technology

Magnetic field independence of the spin gap in YBa_2Cu_3O_{7-delta}

We report, for magnetic fields of 0, 8.8, and 14.8 Tesla, measurements of the temperature dependent ^{63}Cu NMR spin lattice relaxation rate for near optimally doped YBa_2Cu_3O_{7-delta}, near and above T_c. In sharp contrast with previous work we find no magnetic field dependence. We discuss experimental issues arising in measurements of this required precision, and implications of the experiment regarding issues including the spin or pseudo gap.Comment: 4 pages, 3 figures, as accepted for publication in Physical Review Letter

The RNA-binding protein HuR contributes to neuroinflammation by promoting C-C chemokine receptor 6 (CCR6) expression on Th17 cells.

In both multiple sclerosis and experimental autoimmune encephalomyelitis (EAE), the C-C chemokine receptor 6 (CCR6) is critical for pathogenic T helper 17 (Th17) cell migration to the central nervous system (CNS). Whereas many cytokines and their receptors are potently regulated via post-transcriptional mechanisms in response to various stimuli, how CCR6 expression is post-transcriptionally regulated in Th17 cells is unknown. Here, using RNA-binding protein HuR conditional knock-out (KO) and wild-type (WT) mice, we present evidence that HuR post-transcriptionally regulates CCR6 expression by binding to and stabilizing Ccr6 mRNA and by promoting CCR6 translation. We also found that HuR down-regulates several microRNA expressions, which could target the 3\u27-UTR of Ccr6 mRNA for decay. Accordingly, knock-out of HuR reduced CCR6 expression on Th17 cells and impaired their migration to CNS compared with the response of WT Th17 cells and thereby ameliorated EAE. Together, these findings highlight how HuR contributes to Th17 cell-mediated autoimmune neuroinflammation and support the notion that targeting HuR might be a potential therapeutic intervention for managing autoimmune disorders of the CNS

Performance Evaluation of Inverted Tee (IT) Bridge System

The Inverted Tee (IT) girder bridge system was originally developed in 1996 by the University of Nebraska–Lincoln (UNL) researchers and Nebraska Department of Transportation (NDOT) engineers. This bridge system currently accounts for over 110 bridges in Nebraska used for both state highways and local county roads. Extensive longitudinal and transverse deck cracking have been observed and noted in numerous bridge inspection reports. Since the IT girder bridge system is relatively new, limited data and knowledge exist on its structural performance and behavior. This study evaluates the IT girder bridge system by conducting twenty field observations as well as recording accelerometer, strain gauge, and LVDT time histories and lidar scans for a selected subset of these bridges and then a three-dimensional finite element analysis (FEA) was conducted. The field observations included visual inspection for damage and developing deck crack maps to identify a trend for the damage. System identification of the bridge deck and girders helped investigate the global and local structural responses, respectively. Operational modal analysis quantified the natural frequencies, damping ratios, and operational deflected shapes for the instrumented IT girder bridges. These results helped diagnose the reason for the longitudinal deck cracking. The IT girders respond non- uniformly for the first operational deflected shape and independently for higher modes. Two comparable bridges, namely one slab and one NU girder bridge, were instrumented to verify and demonstrate that the IT girder behavior is unique. An advanced geospatial analysis was conducted for the IT girder bridges to develop lidar depth maps of the deck and girders elevations. These depth maps help identify locations of potential water/chloride penetration and girders set at various elevations and/or where the deck thickness is non-uniform. Live load tests helped quantify the transverse dynamic behavior of the bridge girders. Quantifying the transverse dynamic behavior helped validate the source of longitudinal deck cracking in IT girder bridges, which was determined to be the differential deflection between adjacent IT girders. The FEA analysis was conducted to evaluate the live load moment and shear distribution factors and compare that to the predicted values calculated from the AASHTO Standard and LRFD bridge design specifications. The comparison indicated that the predicted distribution factors were conservative. Also, interviews with IT bridge producers and contractors were conducted to determine production and construction advantages and challenges of this bridge system

A-STAR: The All-Sky Transient Astrophysics Reporter

The small mission A-STAR (All-Sky Transient Astrophysics Reporter) aims to locate the X-ray counterparts to ALIGO and other gravitational wave detector sources, to study the poorly-understood low luminosity gamma-ray bursts, and to find a wide variety of transient high-energy source types, A-STAR will survey the entire available sky twice per 24 hours. The payload consists of a coded mask instrument, Owl, operating in the novel low energy band 4-150 keV, and a sensitive wide-field focussing soft X-ray instrument, Lobster, working over 0.15-5 keV. A-STAR will trigger on ~100 GRBs/yr, rapidly distributing their locations.Comment: Accepted for the European Astronomical Society Publications Series: Proceedings of the Fall 2012 Gamma-Ray Burst Symposium held in Marbella, Spain, 8-12 Oct 201

#Scanners 2 – The MOMENT: a new brain-controlled movie

While many still consider interactive movies an unrealistic idea, current delivery platforms like Netflix, commercial VR, and the proliferation of wearable sensors mean that adaptive and responsive entertainment experiences are an immediate reality. Our prior work demonstrated a brain-responsive movie that showed different views of scenes depending on levels of attention and meditation produced by a commercialised home-entertainment brain sensor. Based on lessons learned, this demonstration exhibits the new interactions designed for our new brain-controlled movie, The MOMENT, being released in 2018