34 research outputs found
Use of social networks by college students: A study case in the Iberian Peninsula
La investigaciĂłn que aquĂ se presenta se desarrollĂł durante el segundo
semestre del curso académico 2014/2015, y versa sobre el uso del software
social por parte de los estudiantes del Grado de EducaciĂłn Primaria
pertenecientes a dos instituciones de Educación Superior: Universidad de Jaén
(España) y la Escuela Superior de Educación del Instituto Politécnico de Viana
do Castelo (Portugal). Los objetivos se centran en conocer qué herramientas
de software social utilizan preferentemente el alumnado, cuĂĄles son sus
percepciones sobre estas herramientas para sus posibilidades académicas y si
hay diferencias en funciĂłn de la universidad de procedencia. Se empleĂł como
instrumento de recogida de datos un cuestionario. Se concluye que la red
social mĂĄs conocida y utilizada es Facebook. El hallazgo principal reside en las
diferencias encontradas entre las dos muestras estudiadas en lo concerniente a
su utilizaciĂłnThe research presented here was developed during the second semester of the
academic year 2014/2015, and relates to the use of social software by students
of the Degree in Primary Education from two higher education institutions:
University of Jaén (Spain) and the School of Education at the Polytechnic
Institute of Viana do Castelo (Portugal). The objectives are to know what social
software tools are used mainly by the students, what are their perceptions about
these tools about their academic potential and whether there are differences
depending on the university. It was used as data collection instrument a
questionnaire. We conclude that the best known and used social network is
Facebook. The main finding lies in the differences between the two samples
studied with regard to their us
Los videojuegos: Una nueva estrategia de comunicaciĂłn
En la actualidad, vivimos en un mundo globalizado, dominado por la tecnologĂa donde cada vez resulta mĂĄs difĂcil conseguir una herramienta de entretenimiento que sea efectiva. En las Ășltimas tres dĂ©cadas, los videojuegos han continuado desempeñando el mismo rol que los juegos, pero expandiendo el potencial de los mismos aprovechando las facilidades tecnolĂłgicas con las que contamos en la sociedad actual. El poder de los videojuegos para hacer que sus usuarios sientan las mismas emociones que sienten en la vida real, pero causadas por una realidad alterna o virtual, es lo que hace a esta herramienta tan poderosa. Por ello, no han sido pocas las empresas que han querido aprovechar los videojuegos como herramientas de marketing con el principal objetivo de expandir su imagen de marca.Nowadays, we live in a globalized world, dominated by technology where it is increasingly difficult to find an entertainment tool which is effective. In the last three decades, video games have continued to play the same role as games, but expanding their potential by taking advantage of the technological facilities that we have in today's society. The power of video games to make their users feel the same emotions they feel in real life, but caused by an alternate or virtual reality, is what makes it a powerful tool. For this reason, there have been a lot of companies that have wanted to take advantage of video games as marketing tools with the main objective of expanding their brand image
Impact of FLT3âITD Mutation Status and Its Ratio in a Cohort of 2901 Patients Undergoing Upfront Intensive Chemotherapy: A PETHEMA Registry Study
FLT3âITD results in a poor prognosis in terms of overall survival (OS) and relapse-free survival (RFS) in acute myeloid leukemia (AML). However, the prognostic usefulness of the allelic ratio (AR) to select post-remission therapy remains controversial. Our study focuses on the prognostic impact of FLT3âITD and its ratio in a series of 2901 adult patients treated intensively in the pre-FLT3 inhibitor era and reported in the PETHEMA registry. A total of 579 of these patients (20%) harbored FLT3âITD mutations. In multivariate analyses, patients with an FLT3âITD allele ratio (AR) of >0.5 showed a lower complete remission (CR rate) and OS (HR 1.47, p = 0.009), while AR > 0.8 was associated with poorer RFS (HR 2.1; p 0.5). Using the maximally selected log-rank statistics, we established an optimal cutoff of FLT3âITD AR of 0.44 for OS, and 0.8 for RFS. We analyzed the OS and RFS according to FLT3âITD status in all patients, and we found that the group of FLT3âITD-positive patients with AR 0.44, allo-HSCT was superior to auto-HSCT in terms of OS and RFS. This study provides more evidence for a better characterization of patients with AML harboring FLT3âITD mutations.This study was fundedby Instituto de Salud Carlos III (ISCIII) through the project PI19/01518 and PI19/00730 and co- funded by the European Union, the CRIS Against Cancer Foundation, grant 2018/001, and by the Instituto de InvestigaciĂłn Hospital 12 de Octubre (IMAS12). APeer reviewe
Effectiveness of a cognitive behavioral intervention in patients with medically unexplained symptoms: cluster randomized trial
BACKGROUND: Medically unexplained symptoms are an important mental health problem in primary care and generate a high cost in health services.Cognitive behavioral therapy and psychodynamic therapy have proven effective in these patients. However, there are few studies on the effectiveness of psychosocial interventions by primary health care. The project aims to determine whether a cognitive-behavioral group intervention in patients with medically unexplained symptoms, is more effective than routine clinical practice to improve the quality of life measured by the SF-12 questionary at 12 month. METHODS/DESIGN: This study involves a community based cluster randomized trial in primary healthcare centres in Madrid (Spain). The number of patients required is 242 (121 in each arm), all between 18 and 65 of age with medically unexplained symptoms that had seeked medical attention in primary care at least 10 times during the previous year. The main outcome variable is the quality of life measured by the SF-12 questionnaire on Mental Healthcare. Secondary outcome variables include number of consultations, number of drug (prescriptions) and number of days of sick leave together with other prognosis and descriptive variables. Main effectiveness will be analyzed by comparing the percentage of patients that improve at least 4 points on the SF-12 questionnaire between intervention and control groups at 12 months. All statistical tests will be performed with intention to treat. Logistic regression with random effects will be used to adjust for prognostic factors. Confounding factors or factors that might alter the effect recorded will be taken into account in this analysis. DISCUSSION: This study aims to provide more insight to address medically unexplained symptoms, highly prevalent in primary care, from a quantitative methodology. It involves intervention group conducted by previously trained nursing staff to diminish the progression to the chronicity of the symptoms, improve quality of life, and reduce frequency of medical consultations. TRIAL REGISTRATION: The trial was registered with ClinicalTrials.gov, number NCT01484223 [http://ClinicalTrials.gov].S
Role of age and comorbidities in mortality of patients with infective endocarditis
[Purpose]: The aim of this study was to analyse the characteristics of patients with IE in three groups of age and to assess the ability of age and the Charlson Comorbidity Index (CCI) to predict mortality.
[Methods]: Prospective cohort study of all patients with IE included in the GAMES Spanish database between 2008 and 2015.Patients were stratified into three age groups:<65âŻyears,65 to 80âŻyears,andâŻâ„âŻ80âŻyears.The area under the receiver-operating characteristic (AUROC) curve was calculated to quantify the diagnostic accuracy of the CCI to predict mortality risk.
[Results]: A total of 3120 patients with IE (1327âŻ<âŻ65âŻyears;1291 65-80âŻyears;502âŻâ„âŻ80âŻyears) were enrolled.Fever and heart failure were the most common presentations of IE, with no differences among age groups.Patients â„80âŻyears who underwent surgery were significantly lower compared with other age groups (14.3%,65âŻyears; 20.5%,65-79âŻyears; 31.3%,â„80âŻyears). In-hospital mortality was lower in the <65-year group (20.3%,<65âŻyears;30.1%,65-79âŻyears;34.7%,â„80âŻyears;pâŻ<âŻ0.001) as well as 1-year mortality (3.2%, <65âŻyears; 5.5%, 65-80âŻyears;7.6%,â„80âŻyears; pâŻ=âŻ0.003).Independent predictors of mortality were ageâŻâ„âŻ80âŻyears (hazard ratio [HR]:2.78;95% confidence interval [CI]:2.32â3.34), CCIâŻâ„âŻ3 (HR:1.62; 95% CI:1.39â1.88),and non-performed surgery (HR:1.64;95% CI:11.16â1.58).When the three age groups were compared,the AUROC curve for CCI was significantly larger for patients aged <65âŻyears(pâŻ<âŻ0.001) for both in-hospital and 1-year mortality.
[Conclusion]: There were no differences in the clinical presentation of IE between the groups. AgeâŻâ„âŻ80âŻyears, high comorbidity (measured by CCI),and non-performance of surgery were independent predictors of mortality in patients with IE.CCI could help to identify those patients with IE and surgical indication who present a lower risk of in-hospital and 1-year mortality after surgery, especially in the <65-year group
¿Qué queda de m�
Este libro es una reclamacioÌn a quienes hemos sido, somos o seremos docentes. A quienes no hemos respetado a las personas que se han puesto junto a nosotros y nosotras, confiando su bien maÌs preciado: la libertad. Estas paÌginas denuncian cada vez que convertimos una visioÌn en la visioÌn, una emocioÌn en la emocioÌn, un saber en el saber, un comportamiento en el comportamiento. Es un grito contra la imposicioÌn, la normalizacioÌn, la neutralizacioÌn y la universalizacioÌn de una perspectiva particular. Una pugna contra cada proceso que no se ha conectado con las vidas de los aprendices.
Un texto colaborativo realizado por alumnado de EducacioÌn y Cambio Social en el Grado en EducacioÌn Infantil de la Universidad de MaÌlaga y coordinado por Ignacio CalderoÌn Almendros
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Dietary αâLinolenic Acid, Marine Ïâ3 Fatty Acids, and Mortality in a Population With High Fish Consumption: Findings From the PREvenciĂłn con DIeta MEDiterrĂĄnea (PREDIMED) Study
Background: Epidemiological evidence suggests a cardioprotective role of αâlinolenic acid (ALA), a plantâderived Ïâ3 fatty acid. It is unclear whether ALA is beneficial in a background of high marine Ïâ3 fatty acids (longâchain nâ3 polyunsaturated fatty acids) intake. In persons at high cardiovascular risk from Spain, a country in which fish consumption is customarily high, we investigated whether meeting the International Society for the Study of Fatty Acids and Lipids recommendation for dietary ALA (0.7% of total energy) at baseline was related to allâcause and cardiovascular disease mortality. We also examined the effect of meeting the society's recommendation for longâchain nâ3 polyunsaturated fatty acids (â„500 mg/day). Methods and Results: We longitudinally evaluated 7202 participants in the PREvenciĂłn con DIeta MEDiterrĂĄnea (PREDIMED) trial. Multivariableâadjusted Cox regression models were fitted to estimate hazard ratios. ALA intake correlated to walnut consumption (r=0.94). During a 5.9ây followâup, 431 deaths occurred (104 cardiovascular disease, 55 coronary heart disease, 32 sudden cardiac death, 25 stroke). The hazard ratios for meeting ALA recommendation (n=1615, 22.4%) were 0.72 (95% CI 0.56â0.92) for allâcause mortality and 0.95 (95% CI 0.58â1.57) for fatal cardiovascular disease. The hazard ratios for meeting the recommendation for longâchain nâ3 polyunsaturated fatty acids (n=5452, 75.7%) were 0.84 (95% CI 0.67â1.05) for allâcause mortality, 0.61 (95% CI 0.39â0.96) for fatal cardiovascular disease, 0.54 (95% CI 0.29â0.99) for fatal coronary heart disease, and 0.49 (95% CI 0.22â1.01) for sudden cardiac death. The highest reduction in allâcause mortality occurred in participants meeting both recommendations (hazard ratio 0.63 [95% CI 0.45â0.87]). Conclusions: In participants without prior cardiovascular disease and high fish consumption, dietary ALA, supplied mainly by walnuts and olive oil, relates inversely to allâcause mortality, whereas protection from cardiac mortality is limited to fishâderived longâchain nâ3 polyunsaturated fatty acids. Clinical Trial Registration URL: http://www.Controlled-trials.com/. Unique identifier: ISRCTN35739639
Early mobilisation in critically ill COVID-19 patients: a subanalysis of the ESICM-initiated UNITE-COVID observational study
Background
Early mobilisation (EM) is an intervention that may improve the outcome of critically ill patients. There is limited data on EM in COVID-19 patients and its use during the first pandemic wave.
Methods
This is a pre-planned subanalysis of the ESICM UNITE-COVID, an international multicenter observational study involving critically ill COVID-19 patients in the ICU between February 15th and May 15th, 2020. We analysed variables associated with the initiation of EM (within 72 h of ICU admission) and explored the impact of EM on mortality, ICU and hospital length of stay, as well as discharge location. Statistical analyses were done using (generalised) linear mixed-effect models and ANOVAs.
Results
Mobilisation data from 4190 patients from 280 ICUs in 45 countries were analysed. 1114 (26.6%) of these patients received mobilisation within 72 h after ICU admission; 3076 (73.4%) did not. In our analysis of factors associated with EM, mechanical ventilation at admission (OR 0.29; 95% CI 0.25, 0.35; pâ=â0.001), higher age (OR 0.99; 95% CI 0.98, 1.00; pââ€â0.001), pre-existing asthma (OR 0.84; 95% CI 0.73, 0.98; pâ=â0.028), and pre-existing kidney disease (OR 0.84; 95% CI 0.71, 0.99; pâ=â0.036) were negatively associated with the initiation of EM. EM was associated with a higher chance of being discharged home (OR 1.31; 95% CI 1.08, 1.58; pâ=â0.007) but was not associated with length of stay in ICU (adj. difference 0.91 days; 95% CI â 0.47, 1.37, pâ=â0.34) and hospital (adj. difference 1.4 days; 95% CI â 0.62, 2.35, pâ=â0.24) or mortality (OR 0.88; 95% CI 0.7, 1.09, pâ=â0.24) when adjusted for covariates.
Conclusions
Our findings demonstrate that a quarter of COVID-19 patients received EM. There was no association found between EM in COVID-19 patients' ICU and hospital length of stay or mortality. However, EM in COVID-19 patients was associated with increased odds of being discharged home rather than to a care facility.
Trial registration ClinicalTrials.gov: NCT04836065 (retrospectively registered April 8th 2021)
EducaciĂłn a padres de niños sometidos a cuidados paliativos. RevisiĂłn sistemĂĄtica de ensayos clĂnicos
Los cuidados paliativos pediĂĄtricos consisten en el cuidado total activo del niño y el apoyo a la familia. Es esencial hacer partĂcipes, involucrar y empoderar a padres y cuidadores para poder llevar a cabo unos cuidados paliativos pediĂĄtricos de calidad, siendo la educaciĂłn para la salud el medio mĂĄs oportuno para poder conseguir esto. El objetivo fue conocer la efectividad de la educaciĂłn de los padres en los cuidados paliativos pediĂĄtricos en base a la informaciĂłn de ensayos clĂnicos. Se realizĂł una revisiĂłn sistemĂĄtica siguiendo el protocolo de las normas de la declaraciĂłn PRISMA. Se seleccionaron ensayos clĂnicos aleatorizados en los que la intervenciĂłn de estudio fuese un programa educativo dirigido a padres de niños sometidos a cuidados paliativos o cuidados terminales. No es posible conocer la efectividad de la educaciĂłn a los padres en los cuidados paliativos pediĂĄtricos ya que no se han encontrado ensayos clĂnicos al respecto. Nos parece necesario el desarrollo de investigaciones experimentales, para poder valorar quĂ© tipo de intervenciones son mĂĄs eficaces en este colectivo.
Abstract
Paediatric palliative care entails a comprehensive and active care for the child and support for the family. It is essential to involve and empower parents and caregivers in order to carry out quality paediatric palliative care, being health education the most appropriate way to achieve this. The objective was to assess the effectiveness of parents' education in paediatric palliative care according to information from clinical trials. A systematic review was carried out following the protocol of the PRISMA declaration standards. Randomized clinical trials were selected in which the study intervention was an educational program aimed at parents of children undergoing palliative care or terminal care. It was not possible to assess the effectiveness of education to parents in paediatric palliative care because there were no clinical trials assessing this matter. We believe it is necessary to develop experimental research in order to assess what type of interventions are most effective in this group