True power consumption labeling and mapping of the health system of the Castilla y León region in Spain by clustering techniques

[EN] The latest revisions in April 2018 of the 2010/31/UE and 2012/27/UE Directives on Energy Efficiency and Energy Savings respectively, point out the need of the development of smart energy indexes for buildings with the aim to (i) supervise the energy consumption on the building sector -that currently represents up to one third of the total final energy consumption- and (ii) lead the appropriate actions to transform the current buildings stock to nearly Zero Energy Buildings and Positive Energy Buildings. From public managed buildings, the Health System is the first energy consumer with great difference with other government administration sectors, such as Education or General Administration. Moreover, the energy bill has great impact on the sustainability of the public health care system. However, very few real data were available to characterize the energy demand on public buildings, which are usually the most intensive energy consumers, and efficiency indexes were usually obtained from simulation results. Nevertheless, thanks to the deployment of Smart Metering systems in the last years, it is possible to access to the true energy demand profiles of hundreds of these buildings. In this paper, with three years historical monthly electrical energy consumption data from the health system of the region of Castilla y León in Spain -including hospitals, outpatient facilities, clinics and other medical institutions- and the application of data mining techniques, an end-use electrical energy analysis was conducted to cluster the building housing according to the energy consumption into several energy use intensity clusters and, then, an average value and a Reference Building Energy Index for each cluster is proposed. Thus, a true energy labeling of these buildings based on their distance to the Reference Building Energy Index is done and presented in georeferenced maps.S

Model of monthly electricity consumption of healthcare buildings based on climatological variables using PCA and linear regression

[EN] At this time, due to the global pandemic that has occurred, public administrations want to optimize resources and reduce greenhouse gases with more interest than before. It is the case of the Energy Regional Entity of the Junta de Castilla y León (Spain) that pursues the optimization of the energy consumption in particular of healthcare sector buildings. For this purpose, this work focuses on estimating electricity consumption for each month, for which different scenarios will be generated and the corresponding model is obtained for each scenario. This model has been developed considering the historical monthly data of consumption and climatic variables for the last 3 years. Electricity consumption in public sanitary buildings is related to their climatology, due to the use of air conditioning to adjust the indoor temperature. Subsequently, from the models obtained, the results will be analyzed. Significant differences have been observed in the estimation of electricity consumption with respect to the real data provided by the Junta de Castilla y León. The results obtained show how the availability of climatic variables increases the accuracy of the model obtained by about 30%.S

Estudio de viabilidad para la implantación de dobles titulaciones en la Facultad de Ciencias

Memoria ID-165. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2018-2019

Paleogeografía y Paleosismicidad: El caso de estudio Bajo Segura, SE España

Trabajo presentado en la XIV Reunión Nacional de Cuaternario, celebrada en Granada (España), del 30 de junio al 2 de julio de 2015El presente trabajo aborda el análisis paleogeográfico de la Depresión del Bajo Segura donde se ubicaba la antigua bahía Ibero-Romana del Sinus ilicitanus. Se confrontan datos de reconstrucciones paleogeográficas, documentos históricos con el análisis geomorfológico del sistema de acequias, azudes y canales de la zona y su desarrollo en diferentes periodos. Se concluye que durante la época musulmana la zona afectada por el terremoto en las inmediaciones de Orihuela era un sistema deltáico palmeado 1048 AD se relacionan con fracturación del terreno y procesos de licuefacción, así como un relevante cambio del curso del rí Segura y abandono del sistema deltaico.This work has been funded by the Spanish research projects CGL2012 (QTECTBETICA -USAL), CGL2012-33430 (CSIC) and CGL2013-42847-R (UNED) and W. G. QTECT-AEQUAPeer reviewe

Punto de fuga. Punto de encuentro : aproximación interdisciplinar a las Vanguardias Artísticas de la segunda mitad del siglo XX

Resumen basado en el del proyecto. Premiado en la convocatoria: Premios para proyectos de innovación concluidos durante el curso 2007-2008, en los centros educativos no universitarios sostenidos con fondos públicos de la Comunidad Autónoma de Castilla-La Mancha (Orden 12-12-2008, de la Consejería de Educación y Ciencia de la Junta de Comunidades de Castilla-La Mancha. Resolución de 5-5-2009, de la Viceconsejería de Educación)El proyecto se desarrolla entre cinco centros: la Escuela de Arte de Guadalajarara, la Escuela de Hostelería y Turismo del IES Antonio Buero Vallejo de Guadalajara, el Conservatorio Provincial de Música de Guadalajara, el IES Profesor Domínguez Ortiz de Azuqueca de Henares y el Colegio Infantil y Primaria Castillo de Pioz. La idea central es la de abordar de forma interdisciplinar un tema común entre centros de distinta naturaleza armonizando el calendario de realización. Se buscan elementos integradores que permitan que el alumno se involucre activamente en un aprendizaje significativo con uno de los elementos clave en la educación, la motivación. Los objetivos son: fomentar la idea de que todas las áreas de conocimiento y creación humanas son producto de épocas y situaciones concretas englobadas en un todo; fomentar la participación activa en el proceso educativo; descubrir que el arte es algo vivo y que puede formar parte de la propia personalidad; fomentar el espíritu colectivo, la relevancia en el cumplimiento de los plazos y la valoración de la mirada del espectador sobre lo realizado; descubrir nuevos modos de comunicación y de relación; promover la reflexión anti-racista, anti-sexista, pacifista y solidaria. El tema elegido, la segunda mitad del siglo XX, especialmente las décadas de los 50, 60 y 70. Años de grandes transformaciones sociales y económicas en Europa. Su aproximación es multidisciplinar, desde la música, las artes plásticas, la literatura, la gastronomía, y el desarrollo del turismo como una industria potente que contribuirá además económicamente a sacar del ostracismo al pais.Castilla La ManchaConsejería de Educación, Ciencia y Cultura. Viceconsejería de Educación y Cultura. Servicio de Documentación; Bulevar del Río Alberche, s. n. - 1 Planta; 45071 Toledo; Tel. +34925286045; Fax +34925247410; [email protected]

Switching TNF antagonists in patients with chronic arthritis: An observational study of 488 patients over a four-year period

The objective of this work is to analyze the survival of infliximab, etanercept and adalimumab in patients who have switched among tumor necrosis factor (TNF) antagonists for the treatment of chronic arthritis. BIOBADASER is a national registry of patients with different forms of chronic arthritis who are treated with biologics. Using this registry, we have analyzed patient switching of TNF antagonists. The cumulative discontinuation rate was calculated using the actuarial method. The log-rank test was used to compare survival curves, and Cox regression models were used to assess independent factors associated with discontinuing medication. Between February 2000 and September 2004, 4,706 patients were registered in BIOBADASER, of whom 68% had rheumatoid arthritis, 11% ankylosing spondylitis, 10% psoriatic arthritis, and 11% other forms of chronic arthritis. One- and two-year drug survival rates of the TNF antagonist were 0.83 and 0.75, respectively. There were 488 patients treated with more than one TNF antagonist. In this situation, survival of the second TNF antagonist decreased to 0.68 and 0.60 at 1 and 2 years, respectively. Survival was better in patients replacing the first TNF antagonist because of adverse events (hazard ratio (HR) for discontinuation 0.55 (95% confidence interval (CI), 0.34-0.84)), and worse in patients older than 60 years (HR 1.10 (95% CI 0.97-2.49)) or who were treated with infliximab (HR 3.22 (95% CI 2.13-4.87)). In summary, in patients who require continuous therapy and have failed to respond to a TNF antagonist, replacement with a different TNF antagonist may be of use under certain situations. This issue will deserve continuous reassessment with the arrival of new medications. © 2006 Gomez-Reino and Loreto Carmona; licensee BioMed Central Ltd