The effect of dyslexia on information retrieval: A pilot study

Purpose – The purpose of the paper is to resolve a gap in our knowledge of how people with dyslexia interact with Information Retrieval (IR) systems, specifically an understanding of their information searching behaviour. Very little research has been undertaken with this particular user group, and given the size of the group (an estimated 10% of the population) this lack of knowledge needs to be addressed. Design/Methodology/Approach - We use elements of the dyslexia cognitive profile to design a logging system recording the difference between two sets of participants: dyslexic and control users. We use a standard Okapi interface together with two standard TREC topics in order to record the information searching behaviour of these users. We gather evidence from various sources, including quantitative information on search logs, together with qualitative information from interviews and questionnaires. We record variables on queries, documents, relevance assessments and sessions in the search logs. We use this evidence to examine the difference in searching between the two sets of users, in order to understand the effect of dyslexia on the information searching behaviour. A topic analysis is also conducted on the quantitative data to show any effect on the results from the information need. Research limitations/implications – As this is a pilot study, only 10 participants were recruited for the study, 5 for each user group. Due to ethical issues, the number of topics per search was restricted to one topic only. The study shows that the methodology applied is useful for distinguishing between the two user groups, taking into account differences between topic. We outline further research on the back of this pilot study in four main areas. A different approach from the proposed methodology is needed to measure the effect on query variables, which takes account of topic variation. More details on users are needed such as reading abilities, speed of language processing and working memory to distinguish the user groups. Effect of topic on search interaction must be measured in order to record the potential impact on the dyslexic user group. Work is needed on relevance assessment and effect on precision and recall for users who may not read many documents. Findings – Using the log data, we establish the differences in information searching behaviour of control and dyslexic users i.e. in the way the two groups interact with Okapi, and that qualitative information collected (such as experience etc) may not be able to account for these differences. Evidence from query variables was unable to distinguish between groups, but differences on topic for the same variables were recorded. Users who view more documents tended to judge more documents as being relevant, either in terms of the user group or topic. Session data indicated that there may be an important difference between the number of iterations used in a search between the user groups, as there may be little effect from the topic on this variable. Originality/Value – This is the first study of the effect of dyslexia on information search behaviour, and provides some evidence to take the field forward

International Committee on Mental Health in Cystic Fibrosis: Cystic Fibrosis Foundation and European Cystic Fibrosis Society consensus statements for screening and treating depression and anxiety

Studies measuring psychological distress in individuals with cystic fibrosis (CF) have found high rates of both depression and anxiety. Psychological symptoms in both individuals with CF and parent caregivers have been associated with decreased lung function, lower body mass index, worse adherence, worse health-related quality of life, more frequent hospitalisations and increased healthcare costs. To identify and treat depression and anxiety in CF, the CF Foundation and the European CF Society invited a panel of experts, including physicians, psychologists, psychiatrists, nurses, social workers, a pharmacist, parents and an individual with CF, to develop consensus recommendations for clinical care. Over 18 months, this 22-member committee was divided into four workgroups: Screening; Psychological Interventions; Pharmacological Treatments and Implementation and Future Research, and used the Population, Intervention, Comparison, Outcome methodology to develop questions for literature search and review. Searches were conducted in PubMed, PsychINFO, ScienceDirect, Google Scholar, Psychiatry online and ABDATA by a methodologist at Dartmouth. The committee reviewed 344 articles, drafted statements and set an 80% acceptance for each recommendation statement as a consensus threshold prior to an anonymous voting process. Fifteen guideline recommendation statements for screening and treatment of depression and anxiety in individuals with CF and parent caregivers were finalised by vote. As these recommendations are implemented in CF centres internationally, the process of dissemination, implementation and resource provision should be closely monitored to assess barriers and concerns, validity and use

Are these data real? Statistical methods for the detection of data fabrication in clinical trials.

OBJECTIVES: To test the application of statistical methods to detect data fabrication in a clinical trial. SETTING: Data from two clinical trials: a trial of a dietary intervention for cardiovascular disease and a trial of a drug intervention for the same problem. OUTCOME MEASURES: Baseline comparisons of means and variances of cardiovascular risk factors; digit preference overall and its pattern by group. RESULTS: In the dietary intervention trial, variances for 16 of the 22 variables available at baseline were significantly different, and 10 significant differences were seen in means for these variables. Some of these P values were extraordinarily small. Distributions of the final recorded digit were significantly different between the intervention and the control group at baseline for 14/22 variables in the dietary trial. In the drug trial, only five variables were available, and no significant differences between the groups for baseline values in means or variances or digit preference were seen. CONCLUSIONS: Several statistical features of the data from the dietary trial are so strongly suggestive of data fabrication that no other explanation is likely

Specificity of amino acid sequence and its role in secondary and supersecondary structure generation

Schematic presentation of loops (7 aa) linking two β-strands (fragments of β-sheets). The left one – helical form represents fuzzy oil drop distribution of hydrophobicity. The right one not able to generate the helical form represents the status recognized as amyloid seed in amyloids discussed in this work

Pal Of My Cradle Days / music by Al Piantadosi; words by Marshall Montgomery

Key of Eb. Cover: a drawing of a woman rocking a Cradle; a photo inset of Harry Rappi; Publisher: Leo Feist Inc. (New York)https://egrove.olemiss.edu/sharris_d/1069/thumbnail.jp

Understanding people: A course on qualitative and quantitative HCI research methods

This course will provide an introduction to methods used in Human-Computer Interaction (HCI) research. An equal focus will be given to both the quantitative and qualitative research traditions used to understand people and interactional contexts. We shall discuss these major research traditions along with their contemporary framings (e.g., in-the-wild research and Interaction Science). By the end of the course attendees will have a detailed understanding of how to select and apply methods to address a range of problems that are of concern to contemporary HCI researchers

Research Methods for HCI: Understanding People Using Interactive Technologies

This course will provide an introduction to methods used in Human-Computer Interaction (HCI) research. An equal focus will be given to both the quantitative and qualitative research traditions used to understand people and interactional contexts. We shall discuss these major philosophical traditions along with their contemporary framings (e.g., in-the-wild research and Interaction Science). By the end of the course attendees will have a detailed understanding of how to select and apply methods to address a range of problems that are of concern to contemporary HCI researchers

Key traveller groups of relevance to spatial malaria transmission: a survey of movement patterns in four sub-Saharan African countries

Background: As malaria prevalence declines in many parts of the world due to widescale control efforts and as drug-resistant parasites begin to emerge, a quantitative understanding of human movement is becoming increasingly relevant to malaria control. However, despite its importance, significant knowledge gaps remain regarding human movement, particularly in sub-Saharan Africa. Methods: A quantitative survey of human movement patterns was conducted in four countries in sub-Saharan Africa: Mali, Burkina Faso, Zambia, and Tanzania, with three to five survey locations chosen in each country. Questions were included on demographic and trip details, malaria risk behaviour, children accompanying travellers, and mobile phone usage to enable phone signal data to be better correlated with movement. A total of 4352 individuals were interviewed and 6411 trips recorded. Results: A cluster analysis of trips highlighted two distinct traveller groups of relevance to malaria transmission: women travelling with children (in all four countries) and youth workers (in Mali). Women travelling with children were more likely to travel to areas of relatively high malaria prevalence in Mali (OR = 4.46, 95 % CI = 3.42–5.83), Burkina Faso (OR = 1.58, 95 % CI = 1.23–1.58), Zambia (OR = 1.50, 95 % CI = 1.20–1.89), and Tanzania (OR = 2.28, 95 % CI = 1.71–3.05) compared to other travellers. They were also more likely to own bed nets in Burkina Faso (OR = 1.77, 95 % CI = 1.25–2.53) and Zambia (OR = 1.74, 95 % CI = 1.34 2.27), and less likely to own a mobile phone in Mali (OR = 0.50, 95 % CI = 0.39–0.65), Burkina Faso (OR = 0.39, 95 % CI = 0.30–0.52), and Zambia (OR = 0.60, 95 % CI = 0.47–0.76). Malian youth workers were more likely to travel to areas of relatively high malaria prevalence (OR = 23, 95 % CI = 17–31) and for longer durations (mean of 70 days cf 21 days, p < 0.001) compared to other travellers. Conclusions: Women travelling with children were a remarkably consistent traveller group across all four countries surveyed. They are expected to contribute greatly towards spatial malaria transmission because the children they travel with tend to have high parasite prevalence. Youth workers were a significant traveller group in Mali and are expected to contribute greatly to spatial malaria transmission because their movements correlate with seasonal rains and hence peak mosquito densities. Interventions aimed at interrupting spatial transmission of parasites should consider these traveller groups

Estimating and modeling the dynamics of the intensity of infection with Schistosoma japonicum in villagers of Leyte, Philippines. Part II: Intensity-specific transmission of S. japonicum. The schistosomiasis transmission and ecology project

A dynamic model of Schistosoma japonicum transmission is presented that incorporates effects of infection intensity, age, and sex. We use four infection intensity classes to investigate the impact of ecologic changes and public health interventions on the burden of infection within communities. Age- and sex-specific infection data from three disease-endemic villages in the Philippines are used to estimate the parameters of the model. The model gives good qualitative agreement with observed fecal egg counts adjusted for the accuracy of the Kato-Katz examination. Our results suggest that differences in infection burden between villages are caused by differences in both the infection process and the recovery process in humans. We describe the potential impact of mass treatment of all humans on the numbers with high infection. Furthermore, we show that a sudden reduction in snail population size would affect high prevalence and low prevalence communities in different ways. Copyright © 2005 by The American Society of Tropical Medicine and Hygiene.published_or_final_versio