6,163 research outputs found
Scattering from Solutions of Star Polymers
We calculate the scattering intensity of dilute and semi-dilute solutions of
star polymers. The star conformation is described by a model introduced by
Daoud and Cotton. In this model, a single star is regarded as a spherical
region of a semi-dilute polymer solution with a local, position dependent
screening length. For high enough concentrations, the outer sections of the
arms overlap and build a semi-dilute solution (a sea of blobs) where the inner
parts of the actual stars are embedded. The scattering function is evaluated
following a method introduced by Auvray and de Gennes. In the dilute regime
there are three regions in the scattering function: the Guinier region (low
wave vectors, q R << 1) from where the radius of the star can be extracted; the
intermediate region (1 << q R << f^(2/5)) that carries the signature of the
form factor of a star with f arms: I(q) ~ q^(-10/3); and a high wavevector zone
(q R >> f^(2/5)) where the local swollen structure of the polymers gives rise
to the usual q^(-5/3) decay. In the semi-dilute regime the different stars
interact strongly, and the scattered intensity acquires two new features: a
liquid peak that develops at a reciprocal position corresponding to the
star-star distances; and a new large wavevector contribution of the form
q^(-5/3) originating from the sea of blobs.Comment: REVTeX, 12 pages, 4 eps figure
Visual analytics of Hebrew manuscripts codicological metadata
This paper presents the CodicoDaViz research project, developed with the goal of applying data visualisation techniques to the field of codicology. Adding to the multidisciplinary nature of digital humanities (DH), this project brings together a group of experts of DH, business intelligence and computer science. Using Hebrew manuscript data as a starting point, CodicoDaViz proposes an environment for exploratory analysis to be used by Humanities experts to deepen their understanding of codicological data, and to formulate new research hypotheses. In this paper we demonstrate how data visualisation was instrumental in understanding and structuring the dataset. Examples of the dashboards that have been designed (in Tableau) to enable an interactive and ad-hoc exploration of data are also discussed.info:eu-repo/semantics/acceptedVersio
The Ultrasensitivity of Living Polymers
Synthetic and biological living polymers are self-assembling chains whose
chain length distributions (CLDs) are dynamic. We show these dynamics are
ultrasensitive: even a small perturbation (e.g. temperature jump) non-linearly
distorts the CLD, eliminating or massively augmenting short chains. The origin
is fast relaxation of mass variables (mean chain length, monomer concentration)
which perturbs CLD shape variables before these can relax via slow chain growth
rate fluctuations. Viscosity relaxation predictions agree with experiments on
the best-studied synthetic system, alpha-methylstyrene.Comment: 4 pages, submitted to Phys. Rev. Let
STEADY STATE FIXED BED COMBUSTION OF WOOD PELLETS. A SIMPLE THEORETICAL MODEL
The combustion of biomass follows a sequence of several distinct phases which begin with drying, the subsequent pyrolysis with the release of volatile components that burn in gaseous phase and finally the combustion of carbonaceous resiue, the time consuming step. For small solid fuel boilers, as it is the case of pellet boilers for domestic heating, biomass particles are continuously burned in fixed bed boilers or heaters. In these appliances the furnace is a metallic basket into which fuel particles are thrown and burn. The combustion air is introduced through orifices drilled in this metallic basket although some lateral air entrances are also found. The gaseous flow is a piston flow, the particles fall under gravity on the upper bed surface and as they burn they slowly move downwards until their size is small enough to fall down through the air entrance orifices or are dragged by the upcoming combustion gas flow. So the gaseous current has an up flow movement while the solid particles move downwards. It is assumed that the bed is at uniform temperature and all the average properties of the gaseous flow are constant with the exception of the oxygen concentration that diminishes as the gas flow rises through the bed. The mathematical development of a simple model that allows the calculation of the steady state burning time of a biomass particle in fixed bed, the amount of energy released, the fixed bed size and its particle inventory, is hereby presented. The pedagogical interest of this model is pertinent because it presents, in a synthetic way, the relative importance of the combustion kinetic, the mass transfer mechanism and the reactor fluid dynamics, upon the lifetime of a biochar particle during its combustion process
Influence of GABA and GABA-producing Lactobacillus brevis DPC 6108 on the development of diabetes in a streptozotocin rat model
peer-reviewedThe aim of this study was to investigate if dietary administration of γ-aminobutyric acid (GABA)-producing Lactobacillus brevis DPC 6108 and pure GABA exert protective effects against the development of diabetes in streptozotocin (STZ)-induced diabetic Sprague Dawley rats. In a first experiment, healthy rats were divided in 3 groups (n=10/group) receiving placebo, 2.6 mg/kg body weight (bw) pure GABA or L. brevis DPC 6108 (~109microorganisms). In a second experiment, rats (n=15/group) were randomised to five groups and four of these received an injection of STZ to induce type 1 diabetes. Diabetic and non-diabetic controls received placebo [4% (w/v) yeast extract in dH2O], while the other three diabetic groups received one of the following dietary supplements: 2.6 mg/kg bw GABA (low GABA), 200 mg/kg bw GABA (high GABA) or ~109 L. brevis DPC 6108. L. brevis DPC 6108 supplementation was associated with increased serum insulin levels (P0.05), compared with non-diabetic controls while all other diabetic groups displayed reduced diversity (P<0.05). L. brevis DPC 6108 attenuated hyperglycaemia induced by diabetes but additional studies are needed to understand the mechanisms involved in this reduction.The authors and their work were supported
by the APC Microbiome Institute. The APC Microbiome Institute is funded by Science Foundation Ireland (SFI).
This publication has emanated from research supported by a research grant from Science Foundation Ireland (SFI) under Grant Number SFI/12/RC/2273
Estudo comparativo de métodos de produção de amostras para identificação de espécies de Trichoderma pela técnica MALDI-TOF MS.
Shift-Symmetric Configurations in Two-Dimensional Cellular Automata: Irreversibility, Insolvability, and Enumeration
The search for symmetry as an unusual yet profoundly appealing phenomenon,
and the origin of regular, repeating configuration patterns have long been a
central focus of complexity science and physics. To better grasp and understand
symmetry of configurations in decentralized toroidal architectures, we employ
group-theoretic methods, which allow us to identify and enumerate these inputs,
and argue about irreversible system behaviors with undesired effects on many
computational problems. The concept of so-called configuration shift-symmetry
is applied to two-dimensional cellular automata as an ideal model of
computation. Regardless of the transition function, the results show the
universal insolvability of crucial distributed tasks, such as leader election,
pattern recognition, hashing, and encryption. By using compact enumeration
formulas and bounding the number of shift-symmetric configurations for a given
lattice size, we efficiently calculate the probability of a configuration being
shift-symmetric for a uniform or density-uniform distribution. Further, we
devise an algorithm detecting the presence of shift-symmetry in a
configuration.
Given the resource constraints, the enumeration and probability formulas can
directly help to lower the minimal expected error and provide recommendations
for system's size and initialization. Besides cellular automata, the
shift-symmetry analysis can be used to study the non-linear behavior in various
synchronous rule-based systems that include inference engines, Boolean
networks, neural networks, and systolic arrays.Comment: 22 pages, 9 figures, 2 appendice
A preliminary study of brain macrovascular reactivity in impaired glucose tolerance and type-2 diabetes: Quantitative internal carotid artery blood flow using magnetic resonance phase contrast angiography.
OBJECTIVE: The aims of this study were (1) to examine cerebrovascular autoregulation in subjects with impaired glucose tolerance and type 2 diabetes and (2) to clarify whether cardiovascular autonomic nerve function is associated with abnormal cerebrovascular autoregulation. RESEARCH DESIGN AND METHODS: Totally, 46 subjects were recruited (12 = impaired glucose tolerance, 17 = type 2 diabetes and 17 = healthy volunteers). Arterial blood flow was assessed within the internal carotid artery at baseline and 20 min after intravenous pharmacological stress (1 g acetazolamide), using quantitative magnetic resonance phase-contrast angiography. Internal carotid artery vascular reactivity and pulsatility index was determined. All subjects underwent baroreceptor reflex sensitivity assessment. RESULTS: Subjects with impaired glucose tolerance and type 2 diabetes had significantly lower internal carotid artery vascular reactivity [40.2%(19.8) and 41.5%(18.7)], respectively, compared with healthy volunteers [57.0%(14.2); analysis of variance, p = 0.02]. There was no significant difference in internal carotid artery vascular reactivity between type 2 diabetes and impaired glucose tolerance groups (p = 0.84). There was a significant positive correlation between baroreceptor reflex sensitivity (low frequency:high frequency) with cardiac rhythm variability (ρ = 0.47, p = 0.04) and PI (ρ = 0.46, p = 0.04). CONCLUSION: We have demonstrated significant cerebrovascular haemodynamic abnormalities in subjects with type 2 diabetes and impaired glucose tolerance. This was associated with greater sympathovagal imbalance. This may provide an important mechanistic explanation for increased risk of cerebrovascular disease in diabetes. It also highlights that these abnormalities may already be present in prediabetes
Non-equilibrium Phase Transitions with Long-Range Interactions
This review article gives an overview of recent progress in the field of
non-equilibrium phase transitions into absorbing states with long-range
interactions. It focuses on two possible types of long-range interactions. The
first one is to replace nearest-neighbor couplings by unrestricted Levy flights
with a power-law distribution P(r) ~ r^(-d-sigma) controlled by an exponent
sigma. Similarly, the temporal evolution can be modified by introducing waiting
times Dt between subsequent moves which are distributed algebraically as P(Dt)~
(Dt)^(-1-kappa). It turns out that such systems with Levy-distributed
long-range interactions still exhibit a continuous phase transition with
critical exponents varying continuously with sigma and/or kappa in certain
ranges of the parameter space. In a field-theoretical framework such
algebraically distributed long-range interactions can be accounted for by
replacing the differential operators nabla^2 and d/dt with fractional
derivatives nabla^sigma and (d/dt)^kappa. As another possibility, one may
introduce algebraically decaying long-range interactions which cannot exceed
the actual distance to the nearest particle. Such interactions are motivated by
studies of non-equilibrium growth processes and may be interpreted as Levy
flights cut off at the actual distance to the nearest particle. In the
continuum limit such truncated Levy flights can be described to leading order
by terms involving fractional powers of the density field while the
differential operators remain short-ranged.Comment: LaTeX, 39 pages, 13 figures, minor revision
Genomic analysis of 18th-century kazakh individuals and their oral microbiome
The Asian Central Steppe, consisting of current-day Kazakhstan and Russia, has acted as a highway for major migrations throughout history. Therefore, describing the genetic composition of past populations in Central Asia holds value to understanding human mobility in this pivotal region. In this study, we analyse paleogenomic data generated from five humans from Kuygenzhar, Kazakhstan. These individuals date to the early to mid-18th century, shortly after the Kazakh Khanate was founded, a union of nomadic tribes of Mongol Golden Horde and Turkic origins. Genomic analysis identifies that these individuals are admixed with varying proportions of East Asian ancestry, indicating a recent admixture event from East Asia. The high amounts of DNA from the anaerobic Gram-negative bacteria Tannerella forsythia, a periodontal pathogen, recovered from their teeth suggest they may have suffered from periodontitis disease. Genomic analysis of this bacterium identified recently evolved virulence and glycosylation genes including the presence of antibiotic resistance genes predating the antibiotic era. This study provides an integrated analysis of individuals with a diet mostly based on meat (mainly horse and lamb), milk, and dairy products and their oral microbiome
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