37 research outputs found
The Impact of Emotional Intelligence on Nurses' Professional Quality of Life in Pre‐Hospital Emergency Settings: A Multicentre Mixed‐Method Study
Background: Pre‐hospital emergency nurses, frequently exposed to high‐stress situations, are at risk for burnout and stress‐related issues, affecting their overall well‐being. The Professional Quality of Life (ProQoL) scale, widely used among hospital nurses, remains untested in pre‐hospital emergency settings. Aim: To adapt and validate the ProQoL scale for pre‐hospital emergency contexts and explore the protective role of emotional intelligence in professional well‐being. Methods: A mixed‐method study was conducted. The qualitative approach involved semi‐structured interviews to inform the modification of items for adapting the ProQoL to the pre‐hospital emergency setting. A quantitative method was applied to assess the relationship between emotional intelligence and professional well‐being through content and face validity measures. Results: Qualitative interviews suggested refining the ProQoL for pre‐hospital emergency settings, emphasising factors such as job satisfaction and professional conduct. The revised 21‐item Pre‐Hospital Emergency‐Professional Quality of Life (PHE‐ProQoL) scale demonstrated strong content validity (I‐CVI: 0.86‐1, S‐CVI: 0.9) and face validity. Significant correlations were observed between emotional intelligence and professional well‐being, with negative correlations between emotional intelligence and both burnout (Pearson's r = −0.859) and post‐traumatic stress (Pearson's r = −0.792), and a positive correlation with compassion satisfaction (Pearson's r = +0.917). Pre‐hospital nurses displayed moderate levels of compassion satisfaction (27.3 ± 9.81), high emotional intelligence (28.0 ± 9.58), especially in empathy, and substantial levels of burnout (22.5 ± 6.09) and stress (21.2 ± 4.3). Discussion: The study found that pre‐hospital emergency nurses exhibit moderate compassion satisfaction and above‐average emotional intelligence, particularly in perceiving and managing others' emotions. However, they also experience significant levels of burnout and post‐traumatic stress. Conclusions: Burnout and post‐traumatic stress significantly affect pre‐hospital emergency nurses. Enhancing emotional intelligence is crucial for their well‐being. Nursing managers now have access to a validated and reliable tool to assess this
The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies
Despite the clinical significance of balanced chromosomal abnormalities (BCAs), their characterization has largely been restricted to cytogenetic resolution. We explored the landscape of BCAs at nucleotide resolution in 273 subjects with a spectrum of congenital anomalies. Whole-genome sequencing revised 93% of karyotypes and demonstrated complexity that was cryptic to karyotyping in 21% of BCAs, highlighting the limitations of conventional cytogenetic approaches. At least 33.9% of BCAs resulted in gene disruption that likely contributed to the developmental phenotype, 5.2% were associated with pathogenic genomic imbalances, and 7.3% disrupted topologically associated domains (TADs) encompassing known syndromic loci. Remarkably, BCA breakpoints in eight subjects altered a single TAD encompassing MEF2C, a known driver of 5q14.3 microdeletion syndrome, resulting in decreased MEF2C expression. We propose that sequence-level resolution dramatically improves prediction of clinical outcomes for balanced rearrangements and provides insight into new pathogenic mechanisms, such as altered regulation due to changes in chromosome topology
Diffraction-specific fringe computation for electro-holography
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1994.Vita.Includes bibliographical references (p. 169-173).by Mark Lucente.Ph.D
Optimization of hologram computation for real-time display
Several methods of increasing the speed and simplicity of the computation of off-axis transmission holograms are presented, with applications to the real-time display of holographic images. A bipolar intensity approach enables a linear summation of interference fringes, a factor of two speed increase, and the elimination of image noise caused by object self-interference. An order of magnitude speed increase is obtained through the use of precomputed look-up tables containing a large array of elemental interference patterns corresponding to point source contributions from each of the possible locations in image space. Results achieved using a data-parallel supercomputer to compute horizontal-parallax-only holographic patterns containing 6 megasamples indicate that an image comprised of 10,000 points with arbitrary brightness (grayscale) can be computed in under one second
[Book chapter for “Holography- The First 50 Years ”. Draft: 2003.] Interactive holographic displays: the first 10 years
This chapter reviews the first ten years of interactive electro-holographic displays- from its first instance in 1990 through innovations in computational approaches and optical modulation schemes. The enormous bandwidths required to image three-dimensional (3-D) holographic images interactively are examined, along with descriptions of techniques used to overcome the limitations placed upon fringe computation and optical modulation. Included are the techniques of diffraction-specific fringe computation, computa-tional stereograms, and bipolar fringe computation, as well the scanned acousto-optic modulation technique used in early display systems. Nearly a century passed between the invention of still photography in the nineteenth century and the subse-quent invention of interactive two-dimensional imaging, such as computer-generated graphics and multimedia and video games. Three-dimensional (3-D) holographic imaging became interactive in les