266 research outputs found
Laboratory development of a vertically oriented penetrometer for shallow seabed characterization
Current site investigation practice for offshore pipeline design relies on soil parameters gathered from boreholes or in-situ test soundings to depths of 1-2 m below the mudline. At these depths, the fine-grained seabed is very soft and possesses low undrained strength, which can be difficult to measure. This paper describes a centrifuge test programme undertaken to evaluate the feasibility and performance of a novel penetrometer designed to assess the shallow strength of soft seabed over continuous horizontal profiles. This device is termed the vertically oriented penetrometer (VOP). Tests were performed on a normally consolidated kaolin sample, with the VOP translated horizontally at velocities ranging from 1
– 30 mm/s, after embedding the VOP at 30 mm and 45 mm depths. All tests involved many cycles of VOP forward and backward movement to assess its potential to derive the ratio of intact to fully remoulded strength. Strength determination is achieved by dragging the VOP at a specified embedment depth along the soil surface, and deriving the soil strength from the measured resistance as if the VOP were a laterally loaded pile. The VOP is shown to yield comparable strength measurements to that of a T-bar penetrometer. The VOP is a potentially valuable addition to the range of tools used to characterize soil strength, both in small scale
centrifuge models and, following practical development, potentially also in the field
Large-Deformation Numerical Modeling of Short-Term Compression and Uplift Capacity of Offshore Shallow Foundations
Extracting structural features of rat sciatic nerve using polarization-sensitive spectral domain optical coherence tomography
We present spectral domain polarization-sensitive optical coherence tomography (SD PS-OCT) imaging of peripheral nerves. Structural and polarization-sensitive OCT imaging of uninjured rat sciatic nerves was evaluated both qualitatively and quantitatively. OCT and its functional extension, PS-OCT, were used to image sciatic nerve structure with clear delineation of the nerve boundaries to muscle and adipose tissues. A long-known optical effect, bands of Fontana, was also observed. Postprocessing analysis of these images provided significant quantitative information, such as epineurium thickness, estimates of extinction coefficient and birefringence of nerve and muscle tissue, frequency of bands of Fontana at different stretch levels of nerve, and change in average birefringence of nerve under stretched condition. We demonstrate that PS-OCT combined with regular-intensity OCT (compared with OCT alone) allows for a clearer determination of the inner and outer boundaries of the epineurium and distinction of nerve and muscle based on their birefringence pattern. PS-OCT measurements on normal nerves show that the technique is promising for studies on peripheral nerve injury. © 2012 Society of Photo-Optical Instrumentation Engineers (SPIE)
Optimization of impact pile driving using optical fiber Bragg-grating measurements
This paper reports the use of optical fiber Bragg-grating (FBG) sensors to monitor the stress waves generated below ground during pile driving, combined with measurements using conventional pile driving analyzer (PDA) sensors mounted at the pile head. Fourteen tubular steel piles with a diameter of 508 mm and embedded length-to-diameter ratios of 6∶20 were impact driven at an established chalk test site in Kent, United Kingdom. The pile shafts were instrumented with multiple FBG strain gauges and pile head PDA sensors, which monitored the piles’ responses under each hammer blow. A high-frequency (5 kHz) fiber optic interrogator allowed a previously unseen resolution of the stress wave propagation along the pile. Estimates of the base soil resistances to driving and distributions of shaft shear resistances were found through signal matching that compared the time series of pile head PDA measurements and FBG strains measured below the ground surface. Numerical solutions of the one-dimensional wave equation were optimized by taking account of the data from multiple FBG gauges, leading to significant advantages that have potential for widespread application in cases where high-resolution strain measuremen
Positive Interspecific Relationship between Temporal Occurrence and Abundance in Insects
One of the most studied macroecological patterns is the interspecific abundance–occupancy relationship, which relates species distribution and abundance across space. Interspecific relationships between temporal distribution and abundance, however, remain largely unexplored. Using data for a natural assemblage of tabanid flies measured daily during spring and summer in Nova Scotia, we found that temporal occurrence (proportion of sampling dates in which a species occurred in an experimental trap) was positively related to temporal mean abundance (number of individuals collected for a species during the study period divided by the total number of sampling dates). Moreover, two models that often describe spatial abundance–occupancy relationships well, the He–Gaston and negative binomial models, explained a high amount of the variation in our temporal data. As for the spatial abundance–occupancy relationship, the (temporal) aggregation parameter, k, emerged as an important component of the hereby named interspecific temporal abundance–occurrence relationship. This may be another case in which a macroecological pattern shows similarities across space and time, and it deserves further research because it may improve our ability to forecast colonization dynamics and biological impacts
Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease
OBJECTIVE:
To determine the percentage of children with nonalcoholic fatty liver disease (NAFLD) in whom intervention for low-density lipoprotein cholesterol or triglycerides was indicated based on National Heart, Lung, and Blood Institute guidelines.
STUDY DESIGN:
This multicenter, longitudinal cohort study included children with NAFLD enrolled in the National Institute of Diabetes and Digestive and Kidney Diseases Nonalcoholic Steatohepatitis Clinical Research Network. Fasting lipid profiles were obtained at diagnosis. Standardized dietary recommendations were provided. After 1 year, lipid profiles were repeated and interpreted according to National Heart, Lung, and Blood Institute Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction. Main outcomes were meeting criteria for clinically actionable dyslipidemia at baseline, and either achieving lipid goal at follow-up or meeting criteria for ongoing intervention.
RESULTS:
There were 585 participants, with a mean age of 12.8 years. The prevalence of children warranting intervention for low-density lipoprotein cholesterol at baseline was 14%. After 1 year of recommended dietary changes, 51% achieved goal low-density lipoprotein cholesterol, 27% qualified for enhanced dietary and lifestyle modifications, and 22% met criteria for pharmacologic intervention. Elevated triglycerides were more prevalent, with 51% meeting criteria for intervention. At 1 year, 25% achieved goal triglycerides with diet and lifestyle changes, 38% met criteria for advanced dietary modifications, and 37% qualified for antihyperlipidemic medications.
CONCLUSIONS:
More than one-half of children with NAFLD met intervention thresholds for dyslipidemia. Based on the burden of clinically relevant dyslipidemia, lipid screening in children with NAFLD is warranted. Clinicians caring for children with NAFLD should be familiar with lipid management
Prime Focus Spectrograph (PFS) for the Subaru Telescope: Overview, recent progress, and future perspectives
PFS (Prime Focus Spectrograph), a next generation facility instrument on the
8.2-meter Subaru Telescope, is a very wide-field, massively multiplexed,
optical and near-infrared spectrograph. Exploiting the Subaru prime focus, 2394
reconfigurable fibers will be distributed over the 1.3 deg field of view. The
spectrograph has been designed with 3 arms of blue, red, and near-infrared
cameras to simultaneously observe spectra from 380nm to 1260nm in one exposure
at a resolution of ~1.6-2.7A. An international collaboration is developing this
instrument under the initiative of Kavli IPMU. The project is now going into
the construction phase aiming at undertaking system integration in 2017-2018
and subsequently carrying out engineering operations in 2018-2019. This article
gives an overview of the instrument, current project status and future paths
forward.Comment: 17 pages, 10 figures. Proceeding of SPIE Astronomical Telescopes and
Instrumentation 201
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