Marktanalyse statischer Codeanalysewerkzeuge für Java

Im Rahmen dieser Fachstudie werden statische Codeanalysewerkzeuge für Java untersucht und bewertet. Die Grundlage der Bewertung entsteht durch Absprache zwischen den Autoren dieser Fachstudie und Herr Ostberg. Codeanalysewerkzeuge welche die grundlegenden Anforderungen überstehen, werden einer genaueren Evaluation unterzogen. Am Ende wird auf Grundlage der Evaluation eine Empfehlung für ein Codeanalysewerkzeug ausgesprochen.In this 'Fachstudie' statistical code analysis tools for Java will be studied and evaluated. The basis of the evaluation is derived through an agreement with the authors of this report an Mr. Ostberg. Code analysis tools which outlast these basic requirements will be evaluated thoroughly. At the end of the report a recommendation for one code analysis tool will be issued based on the evaluation

Admissions to acute adolescent psychiatric units: a prospective study of clinical severity and outcome

<p>Abstract</p> <p>Background</p> <p>Several countries have established or are planning acute psychiatric in-patient services that accept around-the-clock emergency admission of adolescents. Our aim was to investigate the characteristics and clinical outcomes of a cohort of patients at four Norwegian units.</p> <p>Methods</p> <p>We used a prospective pre-post observational design. Four units implemented a clinician-rated outcome measure, the Health of the Nation Outcome Scales for Children and Adolescents (HoNOSCA), which measures mental health problems and their severity. We collected also data about the diagnoses, suicidal problems, family situations, and the involvement of the Child Protection Service. Predictions of outcome (change in HoNOSCA <it>total score</it>) were analysed with a regression model.</p> <p>Results</p> <p>The sample comprised 192 adolescents admitted during one year (response rate 87%). Mean age was 15.7 years (range 10-18) and 70% were girls. Fifty-eight per cent had suicidal problems at intake and the mean <it>intake </it>HoNOSCA <it>total score </it>was 18.5 (SD 6.4). The largest groups of main diagnostic conditions were <it>affective </it>(28%) and <it>externalizing </it>(26%) <it>disorders</it>. Diagnoses and other patient characteristics at intake did not differ between units. Clinical psychiatric disorders and developmental disorders were associated with severity (on HoNOSCA) at intake but not with outcome. Of adolescents ≥ 16 years, 33% were compulsorily admitted. Median length of stay was 8.5 days and 75% of patients stayed less than a month. Compulsory admissions and length of stay varied between units. Mean change (improvement) in the HoNOSCA <it>total score </it>was 5.1 (SD 6.2), with considerable variation between units. Mean discharge score was close to the often-reported outpatient level, and <it>self-injury </it>and <it>emotional symptoms </it>were the most reduced symptoms during the stay. In a regression model, unit, high HoNOSCA <it>total score </it>at intake, or involvement of the Child Protection Service predicted improvement during admission.</p> <p>Conclusions</p> <p>Acute psychiatric in-patient units for adolescents effectively meet important needs for young people with suicidal risks or other severe mental health problems. These units may act in suicide prevention, stabilizing symptom severity at a lower level within a short stay. It is important to explore the differences in outcome, compulsory admissions, and length of stay between units.</p

Defective Carbon for Next‐Generation Stationary Energy Storage Systems: Sodium‐Ion and Vanadium Flow Batteries

This review examines the role of defective carbon-based electrodes in sodium-ion and vanadium flow batteries. Methods for introducing defects into carbon structures are explored and their effectiveness in improving electrode performance is demonstrated. In sodium-based systems, research focuses primarily on various precursor materials and heteroatom doping to optimise hard carbon electrodes. Defect engineering increases interlayer spacing, porosity, and changes the surface chemistry, which improves sodium intercalation and reversible capacities. Heteroatom functionalisation and surface modification affect solid electrolyte interface formation and coulombic efficiencies. For flow batteries, post-fabrication electrode enhancement methods produce defects to improve electrode kinetics, although these methods often introduce oxygen functional groups as well, making isolation of defect effects difficult. Continued research efforts are key to developing carbon-based electrodes that can meet the unique challenges of future battery systems

Prospective Sustainability Screening of Sodium-Ion Battery Cathode Materials

Sodium-ion batteries (SIB) are considered as a promising alternative to overcome existing sustainability challenges related to Lithium-ion batteries (LIB), such as the use of critical and expensive materials with high environmental impacts. In contrast to established LIBs, SIBs are an emerging technology in an early stage of development where a challenge is to identify the most promising and sustainable cathode active materials (CAM) for further research and potential commercialization. Thus, a comprehensive and flexible CAM screening method is developed, providing a fast and comprehensive overview of potential sustainability hotspots for supporting cathode material selection. 42 different SIB cathodes are screened and benchmarked against eight state-of-the-art LIB-cathodes. Potential impacts are quantified for the following categories: i) Cost as ten-year average; ii) Criticality, based on existing raw material criticality indicators, and iii) the life cycle carbon footprint. The results reveal that energy density is one of the most important factors in all three categories, determining the overall material demand. Most SIB CAM shows a very promising performance, obtaining better results than the LIB benchmark. Especially the Prussian Blue derivatives and the manganese-based layered oxides seem to be interesting candidates under the given prospective screening framework

Prospective Sustainability Screening of Sodium-Ion Battery Cathode Materials

Sodium-ion batteries (SIB) are considered as a promising alternative to overcome existing sustainability challenges related to Lithium-ion batteries (LIB), such as the use of critical and expensive materials with high environmental impacts. In contrast to established LIBs, SIBs are an emerging technology in an early stage of development where a challenge is to identify the most promising and sustainable cathode active materials (CAM) for further research and potential commercialization. Thus, a comprehensive and flexible CAM screening method is developed, providing a fast and comprehensive overview of potential sustainability hotspots for supporting cathode material selection. 42 different SIB cathodes are screened and benchmarked against eight state-of-the-art LIB-cathodes. Potential impacts are quantified for the following categories: i) Cost as ten-year average; ii) Criticality, based on existing raw material criticality indicators, and iii) the life cycle carbon footprint. The results reveal that energy density is one of the most important factors in all three categories, determining the overall material demand. Most SIB CAM shows a very promising performance, obtaining better results than the LIB benchmark. Especially the Prussian Blue derivatives and the manganese-based layered oxides seem to be interesting candidates under the given prospective screening framework

LIFEDATA - a framework for traceable active learning projects

Active Learning has become a popular method for iteratively improving data-intensive Artificial Intelligence models. However, it often presents a significant challenge when dealing with large volumes of volatile data in projects, as with an Active Learning loop. This paper introduces LIFEDATA, a Python- based framework designed to assist developers in implementing Active Learning projects focusing on traceability. It supports seamless tracking of all artifacts, from data selection and labeling to model interpretation, thus promoting transparency throughout the entire model learning process and enhancing error debugging efficiency while ensuring experiment reproducibility. To showcase its applicability, we present two life science use cases. Moreover, the paper proposes an algorithm that combines query strategies to demonstrate LIFEDATA’s ability to reduce data labeling effort

Thermoelectric spin voltage in graphene

In recent years, new spin-dependent thermal effects have been discovered in ferromagnets, stimulating a growing interest in spin caloritronics, a field that exploits the interaction between spin and heat currents. Amongst the most intriguing phenomena is the spin Seebeck effect, in which a thermal gradient gives rise to spin currents that are detected through the inverse spin Hall effect. Non-magnetic materials such as graphene are also relevant for spin caloritronics, thanks to efficient spin transport, energy-dependent carrier mobility and unique density of states. Here, we propose and demonstrate that a carrier thermal gradient in a graphene lateral spin valve can lead to a large increase of the spin voltage near to the graphene charge neutrality point. Such an increase results from a thermoelectric spin voltage, which is analogous to the voltage in a thermocouple and that can be enhanced by the presence of hot carriers generated by an applied current. These results could prove crucial to drive graphene spintronic devices and, in particular, to sustain pure spin signals with thermal gradients and to tune the remote spin accumulation by varying the spin-injection bias

A bélrendszer kézi és gépi anastomosisainak nyomással szembeni ellenálló képességének felmérése. In vitro kísérletes tanulmány | Experimental study on the resistance to intraluminal pressure between hand-sewn and stapled anastomosis. In vitro experimental study

Absztrakt: Bevezetés és célkitűzés: Tanulmányunk célja volt felmérni a kézi és gépi bélvarratok nyomásrezisztenciáját sertésbélmodellen. Módszer: Különböző típusú kézi és gépi anastomosisokat készítettünk el, az intraluminalis nyomást pedig differenciált nyomású manométerrel mértük. Eredmények: Tapasztalataink szerint nincs szignifikáns különbség a nyomással szembeni ellenállást tekintve, ami a vég a véghez varratokat illeti (p = 0,49). A csonkzáró varratok közül legellenállóbbnak bizonyult a különálló varratsorral történő, két dohányzacskóvarrattal buktatott varrattehnika (p = 0,004). Nem találtunk szignifikáns eltérést a különböző oldal az oldalhoz varratok rezisztenciáját illetően (p = 0,06). Következtetés: Kísérletünk során arra következtettünk, hogy a legellenállóbb varrattípus a kézi csonkzáró varrat, a többi kézi és gépi varrat között nincs jelentős eltérés, ami a nyomással szembeni rezisztenciát illeti. Orv Hetil. 2017; 158(42): 1674–1680. | Abstract: Intoduction and aim: The aim of the study was to compare the resistance to pressure of stapled and manually handsewn intestinal suture lines on in vitro pig intestine model. Method: We performed different types of stapled and manual sutures and the pressure level was measured using a differential pressure manometer. Results: Although the hand-sewn end-to-end suture turned out to be the most resistant to pressure, statistical analysis revealed no significant differences compared to stapled suture (p = 0.49). In stump closure techniques, we observed a statistically high significance in resistance to pressure in the favour of manual stump closure (p = 0.004).Regarding side-to-side sutures we did not find any statistically significant differences in resistance to pressure between the techniques (p = 0.06). Conclusion: We can conclude that regarding the stump closure, the most resistant to pressure is the hand-sewn procedure, but in the other types of anastomosis, no significant differences was found between the stapled and hand-sewn techniques. Orv Hetil. 2017; 158(42): 1674–1680

Building in Quatar - Field excursion of the Faculty of Civil Engineering of the HTWG Konstanz

Die große Exkursion 2010 der Fakultät Bauingenieurwesen führte in das Emirat Qatar am persischen Golf. Qatar verfügt über 15% der weltweiten Reserven anErdgas und investiert u.a. in Infrastruktur- und Bau¬maßnahmen. Deutsche Firmen sind an diesem Aufbau beteiligt. Bei der Exkursion wurden verschiedene Hoch- und Tiefbaustellen, „Mega-Projekte“ deutscher Unternehmen, aber auch eines arabischen Baukonzerns besucht. Auch das Ausstellungszentrum der Deutschen Bahn stand auf dem Programm. Der Bericht gibt die Eindrücke beim Besuch der Projekte wie auch die Reiseerlebnisse wieder.The student excursion of the University of Applied Sciences, Konstanz, Germany, lead to the Emirat of Qatar at the Persian Gulf. The country possesses 15% of the reserves of natural gas and is investing in building and infrastructures measures. German companies are part of this development. During the excursion different structural sites of “mega-projects” of German and Arabic Companies as well as the exposition Center of the “Deutsche Bahn” have been visited

At a glance:the largest Niemann-Pick type C1 cohort with 602 patients diagnosed over 15 years

Niemann-Pick type C1 disease (NPC1 [OMIM 257220]) is a rare and severe autosomal recessive disorder, characterized by a multitude of neurovisceral clinical manifestations and a fatal outcome with no effective treatment to date. Aiming to gain insights into the genetic aspects of the disease, clinical, genetic, and biomarker PPCS data from 602 patients referred from 47 countries and diagnosed with NPC1 in our laboratory were analyzed. Patients’ clinical data were dissected using Human Phenotype Ontology (HPO) terms, and genotype–phenotype analysis was performed. The median age at diagnosis was 10.6 years (range 0–64.5 years), with 287 unique pathogenic/likely pathogenic (P/LP) variants identified, expanding NPC1 allelic heterogeneity. Importantly, 73 P/LP variants were previously unpublished. The most frequent variants detected were: c.3019C &gt; G, p.(P1007A), c.3104C &gt; T, p.(A1035V), and c.2861C &gt; T, p.(S954L). Loss of function (LoF) variants were significantly associated with earlier age at diagnosis, highly increased biomarker levels, and a visceral phenotype (abnormal abdomen and liver morphology). On the other hand, the variants p.(P1007A) and p.(S954L) were significantly associated with later age at diagnosis (p &lt; 0.001) and mildly elevated biomarker levels (p ≤ 0.002), consistent with the juvenile/adult form of NPC1. In addition, p.(I1061T), p.(S954L), and p.(A1035V) were associated with abnormality of eye movements (vertical supranuclear gaze palsy, p ≤ 0.05). We describe the largest and most heterogenous cohort of NPC1 patients published to date. Our results suggest that besides its utility in variant classification, the biomarker PPCS might serve to indicate disease severity/progression. In addition, we establish new genotype–phenotype relationships for “frequent” NPC1 variants.</p