Subsistema Nacional de Recursos Genéticos Acuáticos: uso de la criopreservación para la conservación de los recursos genéticos acuáticos en México

Due to the relevance of mantaining genetic aquatic resources as well as other genetic resources within the alimentary sovereignty of the country, the Secretary of Agriculture, Livestock, Rural Development, Fishery and Food (SAGARPA) and through the General Direction of Technological Transfer and Development and the National Institute of Fishery (INAPESCA), had established the National Subsystem for Aquatic Genetic Resources (SUBNARGENA) which works as an inter-institutional and interdisciplinary network for the conservation and sustainable use of the aquatic biodiversity of Mexico. The objectives of the SUBNARGENA are to localize, collect, conserve (as in situ, ex situ in vivo and ex situ in vitro) and genetically characterize the germplasm of aquatic organism of biological or commercial interest and declared as a priority for the nation. Thus, the goal of this paper is to present the work performed by SUBNARGENA and the advances made in the criopreservation of select aquatic genetic resources of Mexico.Dada la importancia de mantener los recursos genéticos acuáticos, además de otros recursos genéticos en la soberanía alimentaria del país, la Secretaría de Agricultura, Ganadería, Desarrollo Rural, Pesca y Alimentación (SAGARPA) y a través de la Dirección General de Vinculación y Desarrollo Tecnológico y del Instituto Nacional de Pesca (INAPESCA), han establecido el Subsistema Nacional de Recursos Genéticos Acuáticos (SUBNARGENA), el cual funciona como una red interinstitucional e interdisciplinaria para la conservación y aprovechamiento sostenible de la biodiversidad acuática de México. Los objetivos del SUBNARGENA son localizar, recolectar, conservar (de forma in situ, ex situ in vivo y ex situ in vitro), y caracterizar genéticamente el germoplasma de organismos acuáticos de interés biológico o comercial y que son declarados como una prioridad para la nación. Por tanto, el objetivo de este manuscrito es presentar el trabajo realizado por el SUBNARGENA y los avances hechos en la criopreservación de algunos de los recursos genéticos acuáticos de México

Cadmium, Copper, Lead, and Zinc Contents of Fish Marketed in NW Mexico

To assess if they were within the safety limits for human consumption, the Cd, Cu, Pb, and Zn contents of fish muscles, bought from separate stalls of the fish markets of nine cities of NW Mexico, were determined by atomic absorption spectrophotometry. Considering all fish and markets, the mean contents were Zn: 23.23±5.83, Cu: 1.72±0.63, Cd: 0.27 ± 0.07, and Pb: 0.09 ± 0.04 µg/g (dry weight). Cu, Zn, and Pb did not reach levels of concern for human consumption, but the high Cd values determined in Mazatlán (Mugil cephalus: 0.48±0.15; Diapterus spp.: 0.57±0.33; Lutjanus spp.: 0.72±0.12; small shark: 0.87±0.19 µg/g dry weight) indicate that this was the only metal of concern for human health because the daily individual consumption of fish muscle to reach the PTDI would be within 0.27 and 0.41 kg

Polymorphisms in DNA Repair Genes (APEX1, XPD, XRCC1 and XRCC3) and Risk of Preeclampsia in a Mexican Mestizo Population

Variations in genes involved in DNA repair systems have been proposed as risk factors for the development of preeclampsia (PE). We conducted a case-control study to investigate the association of Human apurinic/apyrimidinic (AP) endonuclease (APEX1) Asp148Glu (rs1130409), Xeroderma Pigmentosum group D (XPD) Lys751Gln (rs13181), X-ray repair cross-complementing group 1 (XRCC) Arg399Gln (rs25487) and X-ray repair cross-complementing group 3 (XRCC3) Thr241Met (rs861539) polymorphisms with PE in a Mexican population. Samples of 202 cases and 350 controls were genotyped using RTPCR. Association analyses based on a χ2 test and binary logistic regression were performed to determine the odds ratio (OR) and a 95% confidence interval (95% CI) for each polymorphism. The allelic frequencies of APEX1 Asp148Glu polymorphism showed statistical significant differences between preeclamptic and normal women (p = 0.036). Although neither of the polymorphisms proved to be a risk factor for the disease, the APEX1 Asp148Glu polymorphism showed a tendency of association (OR: 1.74, 95% CI = 0.96–3.14) and a significant trend (p for trend = 0.048). A subgroup analyses revealed differences in the allelic frequencies of APEX1 Asp148Glu polymorphism between women with mild preeclampsia and severe preeclampsia (p = 0.035). In conclusion, our results reveal no association between XPD Lys751Gln, XRCC Arg399Gln and XRCC3 Thr241Met polymorphisms and the risk of PE in a Mexican mestizo population; however, the results in the APEX1 Asp148Glu polymorphism suggest the need for future studies using a larger sample size

The immunogenetic diversity of the HLA system in Mexico correlates with underlying population genetic structure

International audienc

The immunogenetic diversity of the HLA system in Mexico correlates with underlying population genetic structure

International audienc